id sid tid token lemma pos f4752f77x36 1 1 the the DET f4752f77x36 1 2 appearance appearance NOUN f4752f77x36 1 3 of of ADP f4752f77x36 1 4 oxygen oxygen NOUN f4752f77x36 1 5 in in ADP f4752f77x36 1 6 the the DET f4752f77x36 1 7 earth earth NOUN f4752f77x36 1 8 's 's PART f4752f77x36 1 9 atmosphere atmosphere NOUN f4752f77x36 1 10 approximately approximately ADV f4752f77x36 1 11 2.3 2.3 NUM f4752f77x36 1 12 billion billion NUM f4752f77x36 1 13 years year NOUN f4752f77x36 1 14 ago ago ADV f4752f77x36 1 15 led lead VERB f4752f77x36 1 16 to to ADP f4752f77x36 1 17 considerable considerable ADJ f4752f77x36 1 18 changes change NOUN f4752f77x36 1 19 in in ADP f4752f77x36 1 20 the the DET f4752f77x36 1 21 environment environment NOUN f4752f77x36 1 22 . . PUNCT f4752f77x36 2 1 the the DET f4752f77x36 2 2 species specie NOUN f4752f77x36 2 3 that that PRON f4752f77x36 2 4 inhabited inhabit VERB f4752f77x36 2 5 earth earth NOUN f4752f77x36 2 6 , , PUNCT f4752f77x36 2 7 and and CCONJ f4752f77x36 2 8 wished wish VERB f4752f77x36 2 9 to to PART f4752f77x36 2 10 remain remain VERB f4752f77x36 2 11 , , PUNCT f4752f77x36 2 12 had have VERB f4752f77x36 2 13 to to PART f4752f77x36 2 14 adapt adapt VERB f4752f77x36 2 15 to to ADP f4752f77x36 2 16 an an DET f4752f77x36 2 17 oxygen oxygen NOUN f4752f77x36 2 18 - - PUNCT f4752f77x36 2 19 rich rich ADJ f4752f77x36 2 20 atmosphere atmosphere NOUN f4752f77x36 2 21 . . PUNCT f4752f77x36 3 1 at at ADP f4752f77x36 3 2 the the DET f4752f77x36 3 3 biochemical biochemical ADJ f4752f77x36 3 4 level level NOUN f4752f77x36 3 5 , , PUNCT f4752f77x36 3 6 this this PRON f4752f77x36 3 7 forced force VERB f4752f77x36 3 8 the the DET f4752f77x36 3 9 production production NOUN f4752f77x36 3 10 of of ADP f4752f77x36 3 11 enzymes enzyme NOUN f4752f77x36 3 12 and and CCONJ f4752f77x36 3 13 cofactors cofactor NOUN f4752f77x36 3 14 that that PRON f4752f77x36 3 15 were be AUX f4752f77x36 3 16 able able ADJ f4752f77x36 3 17 to to PART f4752f77x36 3 18 react react VERB f4752f77x36 3 19 with with ADP f4752f77x36 3 20 and and CCONJ f4752f77x36 3 21 bind bind VERB f4752f77x36 3 22 oxygen oxygen NOUN f4752f77x36 3 23 , , PUNCT f4752f77x36 3 24 while while SCONJ f4752f77x36 3 25 limiting limit VERB f4752f77x36 3 26 and and CCONJ f4752f77x36 3 27 elminating elminate VERB f4752f77x36 3 28 the the DET f4752f77x36 3 29 toxic toxic ADJ f4752f77x36 3 30 side side NOUN f4752f77x36 3 31 products product NOUN f4752f77x36 3 32 of of ADP f4752f77x36 3 33 its its PRON f4752f77x36 3 34 reduction reduction NOUN f4752f77x36 3 35 . . PUNCT f4752f77x36 4 1 modern modern ADJ f4752f77x36 4 2 species specie NOUN f4752f77x36 4 3 contain contain VERB f4752f77x36 4 4 several several ADJ f4752f77x36 4 5 oxygen oxygen NOUN f4752f77x36 4 6 - - PUNCT f4752f77x36 4 7 reactive reactive ADJ f4752f77x36 4 8 biomolecules biomolecule NOUN f4752f77x36 4 9 that that PRON f4752f77x36 4 10 are be AUX f4752f77x36 4 11 critical critical ADJ f4752f77x36 4 12 for for ADP f4752f77x36 4 13 survival survival NOUN f4752f77x36 4 14 ; ; PUNCT f4752f77x36 4 15 the the DET f4752f77x36 4 16 following following NOUN f4752f77x36 4 17 describes describe VERB f4752f77x36 4 18 an an DET f4752f77x36 4 19 in in ADP f4752f77x36 4 20 - - PUNCT f4752f77x36 4 21 depth depth NOUN f4752f77x36 4 22 examination examination NOUN f4752f77x36 4 23 of of ADP f4752f77x36 4 24 two two NUM f4752f77x36 4 25 enzyme enzyme NOUN f4752f77x36 4 26 systems system NOUN f4752f77x36 4 27 with with ADP f4752f77x36 4 28 evolved evolve VERB f4752f77x36 4 29 highly highly ADV f4752f77x36 4 30 sophisticated sophisticated ADJ f4752f77x36 4 31 mechanisms mechanism NOUN f4752f77x36 4 32 for for ADP f4752f77x36 4 33 the the DET f4752f77x36 4 34 use use NOUN f4752f77x36 4 35 and and CCONJ f4752f77x36 4 36 production production NOUN f4752f77x36 4 37 of of ADP f4752f77x36 4 38 molecular molecular ADJ f4752f77x36 4 39 oxygen oxygen NOUN f4752f77x36 4 40 , , PUNCT f4752f77x36 4 41 respectively respectively ADV f4752f77x36 4 42 . . PUNCT f4752f77x36 5 1 the the DET f4752f77x36 5 2 first first ADJ f4752f77x36 5 3 part part NOUN f4752f77x36 5 4 of of ADP f4752f77x36 5 5 the the DET f4752f77x36 5 6 thesis thesis NOUN f4752f77x36 5 7 describes describe VERB f4752f77x36 5 8 mechanistic mechanistic ADJ f4752f77x36 5 9 studies study NOUN f4752f77x36 5 10 of of ADP f4752f77x36 5 11 a a DET f4752f77x36 5 12 member member NOUN f4752f77x36 5 13 of of ADP f4752f77x36 5 14 a a DET f4752f77x36 5 15 novel novel ADJ f4752f77x36 5 16 subclass subclass NOUN f4752f77x36 5 17 of of ADP f4752f77x36 5 18 n n NOUN f4752f77x36 5 19 - - PUNCT f4752f77x36 5 20 hydroxylating hydroxylate VERB f4752f77x36 5 21 flavin flavin NOUN f4752f77x36 5 22 - - PUNCT f4752f77x36 5 23 dependent dependent ADJ f4752f77x36 5 24 monooxygenases monooxygenase NOUN f4752f77x36 5 25 . . PUNCT f4752f77x36 6 1 the the DET f4752f77x36 6 2 enzyme enzyme PROPN f4752f77x36 6 3 , , PUNCT f4752f77x36 6 4 l l NOUN f4752f77x36 6 5 - - PUNCT f4752f77x36 6 6 ornithine ornithine NOUN f4752f77x36 6 7 monooxygenase monooxygenase NOUN f4752f77x36 6 8 ( ( PUNCT f4752f77x36 6 9 omo omo PROPN f4752f77x36 6 10 ) ) PUNCT f4752f77x36 6 11 , , PUNCT f4752f77x36 6 12 activates activate VERB f4752f77x36 6 13 oxygen oxygen NOUN f4752f77x36 6 14 to to ADP f4752f77x36 6 15 a a DET f4752f77x36 6 16 reactive reactive ADJ f4752f77x36 6 17 flavin flavin NOUN f4752f77x36 6 18 hydroperoxide hydroperoxide NOUN f4752f77x36 6 19 intermediate intermediate ADJ f4752f77x36 6 20 to to PART f4752f77x36 6 21 hydroxylate hydroxylate VERB f4752f77x36 6 22 the the DET f4752f77x36 6 23 primary primary ADJ f4752f77x36 6 24 amine amine NOUN f4752f77x36 6 25 of of ADP f4752f77x36 6 26 l l NOUN f4752f77x36 6 27 - - NOUN f4752f77x36 6 28 ornithine ornithine NOUN f4752f77x36 6 29 in in ADP f4752f77x36 6 30 a a DET f4752f77x36 6 31 critical critical ADJ f4752f77x36 6 32 step step NOUN f4752f77x36 6 33 for for ADP f4752f77x36 6 34 the the DET f4752f77x36 6 35 biosynthesis biosynthesis NOUN f4752f77x36 6 36 of of ADP f4752f77x36 6 37 iron iron NOUN f4752f77x36 6 38 - - PUNCT f4752f77x36 6 39 chelating chelate VERB f4752f77x36 6 40 siderophores siderophore NOUN f4752f77x36 6 41 . . PUNCT f4752f77x36 7 1 the the DET f4752f77x36 7 2 second second ADJ f4752f77x36 7 3 half half NOUN f4752f77x36 7 4 describes describe VERB f4752f77x36 7 5 the the DET f4752f77x36 7 6 cde cde PROPN f4752f77x36 7 7 ( ( PUNCT f4752f77x36 7 8 chlorite chlorite PROPN f4752f77x36 7 9 dismutase dismutase PROPN f4752f77x36 7 10 , , PUNCT f4752f77x36 7 11 dyp dyp NOUN f4752f77x36 7 12 - - PUNCT f4752f77x36 7 13 type type NOUN f4752f77x36 7 14 peroxidase peroxidase NOUN f4752f77x36 7 15 , , PUNCT f4752f77x36 7 16 efeb efeb PROPN f4752f77x36 7 17 ) ) PUNCT f4752f77x36 7 18 protein protein NOUN f4752f77x36 7 19 - - PUNCT f4752f77x36 7 20 family family NOUN f4752f77x36 7 21 . . PUNCT f4752f77x36 8 1 this this DET f4752f77x36 8 2 microbial microbial ADJ f4752f77x36 8 3 protein protein NOUN f4752f77x36 8 4 family family NOUN f4752f77x36 8 5 contains contain VERB f4752f77x36 8 6 the the DET f4752f77x36 8 7 enzyme enzyme NOUN f4752f77x36 8 8 chlorite chlorite NOUN f4752f77x36 8 9 dismutase dismutase NOUN f4752f77x36 8 10 ( ( PUNCT f4752f77x36 8 11 cld cld PROPN f4752f77x36 8 12 ) ) PUNCT f4752f77x36 8 13 , , PUNCT f4752f77x36 8 14 a a DET f4752f77x36 8 15 recently recently ADV f4752f77x36 8 16 discovered discover VERB f4752f77x36 8 17 enzyme enzyme NOUN f4752f77x36 8 18 from from ADP f4752f77x36 8 19 perchlorate perchlorate NOUN f4752f77x36 8 20 ( ( PUNCT f4752f77x36 8 21 clo4- clo4- PROPN f4752f77x36 8 22 ) ) PUNCT f4752f77x36 8 23 respiring respire VERB f4752f77x36 8 24 bacteria bacteria NOUN f4752f77x36 8 25 . . PUNCT f4752f77x36 9 1 these these DET f4752f77x36 9 2 organisms organism NOUN f4752f77x36 9 3 have have AUX f4752f77x36 9 4 achieved achieve VERB f4752f77x36 9 5 the the DET f4752f77x36 9 6 ability ability NOUN f4752f77x36 9 7 to to PART f4752f77x36 9 8 respire respire NOUN f4752f77x36 9 9 oxochlorates oxochlorate NOUN f4752f77x36 9 10 and and CCONJ f4752f77x36 9 11 make make VERB f4752f77x36 9 12 use use NOUN f4752f77x36 9 13 of of ADP f4752f77x36 9 14 the the DET f4752f77x36 9 15 man man NOUN f4752f77x36 9 16 - - PUNCT f4752f77x36 9 17 made make VERB f4752f77x36 9 18 molecules molecule NOUN f4752f77x36 9 19 for for ADP f4752f77x36 9 20 their their PRON f4752f77x36 9 21 survival survival NOUN f4752f77x36 9 22 . . PUNCT f4752f77x36 10 1 cld cld PROPN f4752f77x36 10 2 is be AUX f4752f77x36 10 3 a a DET f4752f77x36 10 4 heme heme NOUN f4752f77x36 10 5 - - PUNCT f4752f77x36 10 6 dependent dependent ADJ f4752f77x36 10 7 enzyme enzyme NOUN f4752f77x36 10 8 that that PRON f4752f77x36 10 9 catalyzes catalyze VERB f4752f77x36 10 10 the the DET f4752f77x36 10 11 conversion conversion NOUN f4752f77x36 10 12 of of ADP f4752f77x36 10 13 chlorite chlorite NOUN f4752f77x36 10 14 ( ( PUNCT f4752f77x36 10 15 clo2- clo2- PROPN f4752f77x36 10 16 ) ) PUNCT f4752f77x36 10 17 , , PUNCT f4752f77x36 10 18 the the DET f4752f77x36 10 19 toxic toxic ADJ f4752f77x36 10 20 end end NOUN f4752f77x36 10 21 product product NOUN f4752f77x36 10 22 of of ADP f4752f77x36 10 23 perchlorate perchlorate NOUN f4752f77x36 10 24 respiration respiration NOUN f4752f77x36 10 25 , , PUNCT f4752f77x36 10 26 to to ADP f4752f77x36 10 27 molecular molecular ADJ f4752f77x36 10 28 oxygen oxygen NOUN f4752f77x36 10 29 ( ( PUNCT f4752f77x36 10 30 o2 o2 PROPN f4752f77x36 10 31 ) ) PUNCT f4752f77x36 10 32 and and CCONJ f4752f77x36 10 33 chloride chloride PROPN f4752f77x36 10 34 ( ( PUNCT f4752f77x36 10 35 cl- cl- SPACE f4752f77x36 10 36 ) ) PUNCT f4752f77x36 10 37 . . PUNCT f4752f77x36 11 1 studies study NOUN f4752f77x36 11 2 to to PART f4752f77x36 11 3 understand understand VERB f4752f77x36 11 4 cld cld PROPN f4752f77x36 11 5 's 's PART f4752f77x36 11 6 detailed detailed ADJ f4752f77x36 11 7 chemical chemical NOUN f4752f77x36 11 8 mechanism mechanism NOUN f4752f77x36 11 9 and and CCONJ f4752f77x36 11 10 the the DET f4752f77x36 11 11 protein protein NOUN f4752f77x36 11 12 residues residue VERB f4752f77x36 11 13 essential essential ADJ f4752f77x36 11 14 for for ADP f4752f77x36 11 15 its its PRON f4752f77x36 11 16 function function NOUN f4752f77x36 11 17 are be AUX f4752f77x36 11 18 described describe VERB f4752f77x36 11 19 . . PUNCT f4752f77x36 12 1 the the DET f4752f77x36 12 2 large large ADJ f4752f77x36 12 3 cde cde PROPN f4752f77x36 12 4 protein protein NOUN f4752f77x36 12 5 - - PUNCT f4752f77x36 12 6 family family NOUN f4752f77x36 12 7 , , PUNCT f4752f77x36 12 8 to to PART f4752f77x36 12 9 which which PRON f4752f77x36 12 10 cld cld NOUN f4752f77x36 12 11 belongs belong VERB f4752f77x36 12 12 , , PUNCT f4752f77x36 12 13 is be AUX f4752f77x36 12 14 described describe VERB f4752f77x36 12 15 in in ADP f4752f77x36 12 16 detail detail NOUN f4752f77x36 12 17 with with ADP f4752f77x36 12 18 structural structural ADJ f4752f77x36 12 19 and and CCONJ f4752f77x36 12 20 sequence sequence NOUN f4752f77x36 12 21 based base VERB f4752f77x36 12 22 analyses analysis NOUN f4752f77x36 12 23 . . PUNCT f4752f77x36 13 1 work work NOUN f4752f77x36 13 2 shows show VERB f4752f77x36 13 3 that that SCONJ f4752f77x36 13 4 several several ADJ f4752f77x36 13 5 annotated annotate VERB f4752f77x36 13 6 cld cld NOUN f4752f77x36 13 7 genes gene NOUN f4752f77x36 13 8 are be AUX f4752f77x36 13 9 found find VERB f4752f77x36 13 10 in in ADP f4752f77x36 13 11 non non ADJ f4752f77x36 13 12 - - ADJ f4752f77x36 13 13 perchlorate perchlorate ADJ f4752f77x36 13 14 respiring respire VERB f4752f77x36 13 15 bacteria bacteria NOUN f4752f77x36 13 16 and and CCONJ f4752f77x36 13 17 likely likely ADV f4752f77x36 13 18 have have VERB f4752f77x36 13 19 as as ADV f4752f77x36 13 20 yet yet ADV f4752f77x36 13 21 unidentified unidentified ADJ f4752f77x36 13 22 non non ADJ f4752f77x36 13 23 - - ADJ f4752f77x36 13 24 dismutase dismutase ADJ f4752f77x36 13 25 functions function NOUN f4752f77x36 13 26 . . PUNCT f4752f77x36 14 1 in in ADP f4752f77x36 14 2 the the DET f4752f77x36 14 3 last last ADJ f4752f77x36 14 4 chapter chapter NOUN f4752f77x36 14 5 , , PUNCT f4752f77x36 14 6 biochemical biochemical ADJ f4752f77x36 14 7 and and CCONJ f4752f77x36 14 8 microbiological microbiological ADJ f4752f77x36 14 9 data datum NOUN f4752f77x36 14 10 are be AUX f4752f77x36 14 11 presented present VERB f4752f77x36 14 12 with with ADP f4752f77x36 14 13 an an DET f4752f77x36 14 14 effort effort NOUN f4752f77x36 14 15 towards towards ADP f4752f77x36 14 16 determining determine VERB f4752f77x36 14 17 the the DET f4752f77x36 14 18 biological biological ADJ f4752f77x36 14 19 function function NOUN f4752f77x36 14 20 of of ADP f4752f77x36 14 21 a a DET f4752f77x36 14 22 cld cld NOUN f4752f77x36 14 23 homolog homolog NOUN f4752f77x36 14 24 in in ADP f4752f77x36 14 25 the the DET f4752f77x36 14 26 pathogenic pathogenic ADJ f4752f77x36 14 27 species specie NOUN f4752f77x36 14 28 staphyloccoccus staphyloccoccus ADJ f4752f77x36 14 29 aureus aureus NOUN f4752f77x36 14 30 . . PUNCT f4752f77x36 15 1 the the DET f4752f77x36 15 2 biological biological ADJ f4752f77x36 15 3 roles role NOUN f4752f77x36 15 4 of of ADP f4752f77x36 15 5 both both CCONJ f4752f77x36 15 6 the the DET f4752f77x36 15 7 l l NOUN f4752f77x36 15 8 - - PUNCT f4752f77x36 15 9 ornithine ornithine NOUN f4752f77x36 15 10 monooxygenase monooxygenase NOUN f4752f77x36 15 11 and and CCONJ f4752f77x36 15 12 chlorite chlorite NOUN f4752f77x36 15 13 dismutase dismutase NOUN f4752f77x36 15 14 center center NOUN f4752f77x36 15 15 around around ADP f4752f77x36 15 16 redox redox ADJ f4752f77x36 15 17 biochemistry biochemistry NOUN f4752f77x36 15 18 , , PUNCT f4752f77x36 15 19 and and CCONJ f4752f77x36 15 20 each each DET f4752f77x36 15 21 story story NOUN f4752f77x36 15 22 will will AUX f4752f77x36 15 23 be be AUX f4752f77x36 15 24 described describe VERB f4752f77x36 15 25 within within ADP f4752f77x36 15 26 the the DET f4752f77x36 15 27 context context NOUN f4752f77x36 15 28 of of ADP f4752f77x36 15 29 microbial microbial ADJ f4752f77x36 15 30 redox redox ADJ f4752f77x36 15 31 cofactor cofactor NOUN f4752f77x36 15 32 acquisition acquisition NOUN f4752f77x36 15 33 , , PUNCT f4752f77x36 15 34 synthesis synthesis NOUN f4752f77x36 15 35 , , PUNCT f4752f77x36 15 36 storage storage NOUN f4752f77x36 15 37 , , PUNCT f4752f77x36 15 38 and and CCONJ f4752f77x36 15 39 utilization utilization NOUN f4752f77x36 15 40 . . PUNCT f4752f77x36 16 1 the the DET f4752f77x36 16 2 importance importance NOUN f4752f77x36 16 3 of of ADP f4752f77x36 16 4 each each PRON f4752f77x36 16 5 is be AUX f4752f77x36 16 6 described describe VERB f4752f77x36 16 7 in in ADP f4752f77x36 16 8 regard regard NOUN f4752f77x36 16 9 to to ADP f4752f77x36 16 10 virulence virulence NOUN f4752f77x36 16 11 in in ADP f4752f77x36 16 12 pathogenic pathogenic ADJ f4752f77x36 16 13 species specie NOUN f4752f77x36 16 14 and and CCONJ f4752f77x36 16 15 the the DET f4752f77x36 16 16 potential potential ADJ f4752f77x36 16 17 development development NOUN f4752f77x36 16 18 of of ADP f4752f77x36 16 19 new new ADJ f4752f77x36 16 20 antimicrobial antimicrobial ADJ f4752f77x36 16 21 targets target NOUN f4752f77x36 16 22 . . PUNCT