id sid tid token lemma pos dv13zs2842v 1 1 the the DET dv13zs2842v 1 2 biological biological ADJ dv13zs2842v 1 3 membrane membrane NOUN dv13zs2842v 1 4 is be AUX dv13zs2842v 1 5 made make VERB dv13zs2842v 1 6 up up ADP dv13zs2842v 1 7 of of ADP dv13zs2842v 1 8 primarily primarily ADV dv13zs2842v 1 9 polar polar ADJ dv13zs2842v 1 10 lipids lipid NOUN dv13zs2842v 1 11 and and CCONJ dv13zs2842v 1 12 integral integral ADJ dv13zs2842v 1 13 membrane membrane NOUN dv13zs2842v 1 14 proteins protein NOUN dv13zs2842v 1 15 . . PUNCT dv13zs2842v 2 1 polar polar ADJ dv13zs2842v 2 2 lipids lipid NOUN dv13zs2842v 2 3 are be AUX dv13zs2842v 2 4 a a DET dv13zs2842v 2 5 broad broad ADJ dv13zs2842v 2 6 class class NOUN dv13zs2842v 2 7 of of ADP dv13zs2842v 2 8 amphiphilic amphiphilic ADJ dv13zs2842v 2 9 biomolecules biomolecule NOUN dv13zs2842v 2 10 that that PRON dv13zs2842v 2 11 serve serve VERB dv13zs2842v 2 12 diverse diverse ADJ dv13zs2842v 2 13 biological biological ADJ dv13zs2842v 2 14 roles role NOUN dv13zs2842v 2 15 encompassing encompass VERB dv13zs2842v 2 16 energy energy NOUN dv13zs2842v 2 17 storage storage NOUN dv13zs2842v 2 18 , , PUNCT dv13zs2842v 2 19 cell cell NOUN dv13zs2842v 2 20 compartmentalization compartmentalization NOUN dv13zs2842v 2 21 , , PUNCT dv13zs2842v 2 22 and and CCONJ dv13zs2842v 2 23 cell cell NOUN dv13zs2842v 2 24 signaling signaling NOUN dv13zs2842v 2 25 . . PUNCT dv13zs2842v 3 1 the the DET dv13zs2842v 3 2 first first ADJ dv13zs2842v 3 3 part part NOUN dv13zs2842v 3 4 of of ADP dv13zs2842v 3 5 the the DET dv13zs2842v 3 6 dissertation dissertation NOUN dv13zs2842v 3 7 is be AUX dv13zs2842v 3 8 an an DET dv13zs2842v 3 9 introduction introduction NOUN dv13zs2842v 3 10 to to ADP dv13zs2842v 3 11 the the DET dv13zs2842v 3 12 structures structure NOUN dv13zs2842v 3 13 of of ADP dv13zs2842v 3 14 polar polar ADJ dv13zs2842v 3 15 lipids lipid NOUN dv13zs2842v 3 16 and and CCONJ dv13zs2842v 3 17 their their PRON dv13zs2842v 3 18 self self NOUN dv13zs2842v 3 19 - - PUNCT dv13zs2842v 3 20 assembly assembly NOUN dv13zs2842v 3 21 properties property NOUN dv13zs2842v 3 22 followed follow VERB dv13zs2842v 3 23 by by ADP dv13zs2842v 3 24 a a DET dv13zs2842v 3 25 summary summary NOUN dv13zs2842v 3 26 of of ADP dv13zs2842v 3 27 biological biological ADJ dv13zs2842v 3 28 strategies strategy NOUN dv13zs2842v 3 29 for for ADP dv13zs2842v 3 30 polar polar ADJ dv13zs2842v 3 31 lipid lipid NOUN dv13zs2842v 3 32 recognition recognition NOUN dv13zs2842v 3 33 . . PUNCT dv13zs2842v 4 1 the the DET dv13zs2842v 4 2 final final ADJ dv13zs2842v 4 3 section section NOUN dv13zs2842v 4 4 of of ADP dv13zs2842v 4 5 the the DET dv13zs2842v 4 6 first first ADJ dv13zs2842v 4 7 chapter chapter NOUN dv13zs2842v 4 8 is be AUX dv13zs2842v 4 9 an an DET dv13zs2842v 4 10 introduction introduction NOUN dv13zs2842v 4 11 to to ADP dv13zs2842v 4 12 synthetic synthetic ADJ dv13zs2842v 4 13 receptors receptor NOUN dv13zs2842v 4 14 for for ADP dv13zs2842v 4 15 polar polar ADJ dv13zs2842v 4 16 lipids lipid NOUN dv13zs2842v 4 17 . . PUNCT dv13zs2842v 5 1 the the DET dv13zs2842v 5 2 next next ADJ dv13zs2842v 5 3 two two NUM dv13zs2842v 5 4 chapters chapter NOUN dv13zs2842v 5 5 focus focus VERB dv13zs2842v 5 6 on on ADP dv13zs2842v 5 7 research research NOUN dv13zs2842v 5 8 towards towards ADP dv13zs2842v 5 9 new new ADJ dv13zs2842v 5 10 probes probe NOUN dv13zs2842v 5 11 for for ADP dv13zs2842v 5 12 anionic anionic ADJ dv13zs2842v 5 13 phospholipids phospholipid NOUN dv13zs2842v 5 14 such such ADJ dv13zs2842v 5 15 as as ADP dv13zs2842v 5 16 phosphatidylserine phosphatidylserine NOUN dv13zs2842v 5 17 ( ( PUNCT dv13zs2842v 5 18 ps ps NOUN dv13zs2842v 5 19 ) ) PUNCT dv13zs2842v 5 20 using use VERB dv13zs2842v 5 21 synthetic synthetic ADJ dv13zs2842v 5 22 zinc(ii)-bis(dipicolylamine zinc(ii)-bis(dipicolylamine NOUN dv13zs2842v 5 23 ) ) PUNCT dv13zs2842v 5 24 ( ( PUNCT dv13zs2842v 5 25 zn2bdpa zn2bdpa SPACE dv13zs2842v 5 26 ) ) PUNCT dv13zs2842v 5 27 coordination coordination NOUN dv13zs2842v 5 28 complexes complex NOUN dv13zs2842v 5 29 . . PUNCT dv13zs2842v 6 1 ps ps PROPN dv13zs2842v 6 2 targeting target VERB dv13zs2842v 6 3 is be AUX dv13zs2842v 6 4 relevant relevant ADJ dv13zs2842v 6 5 to to PART dv13zs2842v 6 6 cell cell NOUN dv13zs2842v 6 7 death death NOUN dv13zs2842v 6 8 since since SCONJ dv13zs2842v 6 9 ps ps PRON dv13zs2842v 6 10 is be AUX dv13zs2842v 6 11 exposed expose VERB dv13zs2842v 6 12 on on ADP dv13zs2842v 6 13 the the DET dv13zs2842v 6 14 surface surface NOUN dv13zs2842v 6 15 of of ADP dv13zs2842v 6 16 dead dead ADJ dv13zs2842v 6 17 and and CCONJ dv13zs2842v 6 18 dying die VERB dv13zs2842v 6 19 cells cell NOUN dv13zs2842v 6 20 . . PUNCT dv13zs2842v 6 21 zn2bdpa zn2bdpa PUNCT dv13zs2842v 7 1 coordination coordination NOUN dv13zs2842v 7 2 complexes complex NOUN dv13zs2842v 7 3 are be AUX dv13zs2842v 7 4 known know VERB dv13zs2842v 7 5 to to PART dv13zs2842v 7 6 selectively selectively ADV dv13zs2842v 7 7 recognize recognize VERB dv13zs2842v 7 8 ps ps PROPN dv13zs2842v 7 9 - - PUNCT dv13zs2842v 7 10 rich rich ADJ dv13zs2842v 7 11 membranes membrane NOUN dv13zs2842v 7 12 and and CCONJ dv13zs2842v 7 13 act act VERB dv13zs2842v 7 14 as as ADP dv13zs2842v 7 15 cell cell NOUN dv13zs2842v 7 16 death death NOUN dv13zs2842v 7 17 molecular molecular ADJ dv13zs2842v 7 18 imaging image VERB dv13zs2842v 7 19 agents agent NOUN dv13zs2842v 7 20 . . PUNCT dv13zs2842v 8 1 however however ADV dv13zs2842v 8 2 , , PUNCT dv13zs2842v 8 3 there there PRON dv13zs2842v 8 4 is be VERB dv13zs2842v 8 5 a a DET dv13zs2842v 8 6 need need NOUN dv13zs2842v 8 7 to to PART dv13zs2842v 8 8 improve improve VERB dv13zs2842v 8 9 in in ADP dv13zs2842v 8 10 vivo vivo NOUN dv13zs2842v 8 11 imaging imaging NOUN dv13zs2842v 8 12 performance performance NOUN dv13zs2842v 8 13 by by ADP dv13zs2842v 8 14 selectively selectively ADV dv13zs2842v 8 15 increasing increase VERB dv13zs2842v 8 16 target target NOUN dv13zs2842v 8 17 affinity affinity NOUN dv13zs2842v 8 18 and and CCONJ dv13zs2842v 8 19 decreasing decrease VERB dv13zs2842v 8 20 off off ADP dv13zs2842v 8 21 - - PUNCT dv13zs2842v 8 22 target target NOUN dv13zs2842v 8 23 accumulation accumulation NOUN dv13zs2842v 8 24 . . PUNCT dv13zs2842v 9 1 the the DET dv13zs2842v 9 2 first first ADJ dv13zs2842v 9 3 study study NOUN dv13zs2842v 9 4 ( ( PUNCT dv13zs2842v 9 5 chapter chapter NOUN dv13zs2842v 9 6 2 2 NUM dv13zs2842v 9 7 ) ) PUNCT dv13zs2842v 9 8 focuses focus VERB dv13zs2842v 9 9 on on ADP dv13zs2842v 9 10 the the DET dv13zs2842v 9 11 synthesis synthesis NOUN dv13zs2842v 9 12 and and CCONJ dv13zs2842v 9 13 screening screening NOUN dv13zs2842v 9 14 of of ADP dv13zs2842v 9 15 a a DET dv13zs2842v 9 16 small small ADJ dv13zs2842v 9 17 library library NOUN dv13zs2842v 9 18 of of ADP dv13zs2842v 9 19 modified modify VERB dv13zs2842v 9 20 zn2bdpa zn2bdpa PUNCT dv13zs2842v 9 21 complexes complex NOUN dv13zs2842v 9 22 constructed construct VERB dv13zs2842v 9 23 through through ADP dv13zs2842v 9 24 the the DET dv13zs2842v 9 25 oxime oxime ADJ dv13zs2842v 9 26 ligation ligation NOUN dv13zs2842v 9 27 to to PART dv13zs2842v 9 28 better well ADV dv13zs2842v 9 29 understand understand VERB dv13zs2842v 9 30 the the DET dv13zs2842v 9 31 structural structural ADJ dv13zs2842v 9 32 requirements requirement NOUN dv13zs2842v 9 33 for for ADP dv13zs2842v 9 34 membrane membrane NOUN dv13zs2842v 9 35 ps ps PROPN dv13zs2842v 9 36 recognition recognition NOUN dv13zs2842v 9 37 . . PUNCT dv13zs2842v 10 1 the the DET dv13zs2842v 10 2 second second ADJ dv13zs2842v 10 3 study study NOUN dv13zs2842v 10 4 ( ( PUNCT dv13zs2842v 10 5 chapter chapter NOUN dv13zs2842v 10 6 3 3 NUM dv13zs2842v 10 7 ) ) PUNCT dv13zs2842v 10 8 compares compare VERB dv13zs2842v 10 9 the the DET dv13zs2842v 10 10 cell cell NOUN dv13zs2842v 10 11 death death NOUN dv13zs2842v 10 12 targeting target VERB dv13zs2842v 10 13 ability ability NOUN dv13zs2842v 10 14 of of ADP dv13zs2842v 10 15 two two NUM dv13zs2842v 10 16 new new ADJ dv13zs2842v 10 17 phenoxide phenoxide NOUN dv13zs2842v 10 18 - - PUNCT dv13zs2842v 10 19 bridged bridge VERB dv13zs2842v 10 20 zn2bdpa zn2bdpa X dv13zs2842v 10 21 deep deep ADJ dv13zs2842v 10 22 - - PUNCT dv13zs2842v 10 23 red red ADJ dv13zs2842v 10 24 fluorescent fluorescent NOUN dv13zs2842v 10 25 probes probe NOUN dv13zs2842v 10 26 in in ADP dv13zs2842v 10 27 cells cell NOUN dv13zs2842v 10 28 and and CCONJ dv13zs2842v 10 29 two two NUM dv13zs2842v 10 30 animal animal NOUN dv13zs2842v 10 31 models model NOUN dv13zs2842v 10 32 of of ADP dv13zs2842v 10 33 cell cell NOUN dv13zs2842v 10 34 death death NOUN dv13zs2842v 10 35 . . PUNCT dv13zs2842v 11 1 an an DET dv13zs2842v 11 2 [ [ X dv13zs2842v 11 3 111]in 111]in NUM dv13zs2842v 11 4 - - PUNCT dv13zs2842v 11 5 labelled label VERB dv13zs2842v 11 6 radiotracer radiotracer ADJ dv13zs2842v 11 7 version version NOUN dv13zs2842v 11 8 of of ADP dv13zs2842v 11 9 the the DET dv13zs2842v 11 10 monovalent monovalent NOUN dv13zs2842v 11 11 probe probe NOUN dv13zs2842v 11 12 also also ADV dv13zs2842v 11 13 exhibited exhibit VERB dv13zs2842v 11 14 selective selective ADJ dv13zs2842v 11 15 cell cell NOUN dv13zs2842v 11 16 death death NOUN dv13zs2842v 11 17 targeting target VERB dv13zs2842v 11 18 with with ADP dv13zs2842v 11 19 the the DET dv13zs2842v 11 20 most most ADV dv13zs2842v 11 21 favorable favorable ADJ dv13zs2842v 11 22 in in ADP dv13zs2842v 11 23 vivo vivo ADJ dv13zs2842v 11 24 biodistribution biodistribution NOUN dv13zs2842v 11 25 profile profile NOUN dv13zs2842v 11 26 yet yet ADV dv13zs2842v 11 27 reported report VERB dv13zs2842v 11 28 for for ADP dv13zs2842v 11 29 a a DET dv13zs2842v 11 30 zn2bdpa zn2bdpa ADJ dv13zs2842v 11 31 complex complex NOUN dv13zs2842v 11 32 . . PUNCT dv13zs2842v 12 1 thus thus ADV dv13zs2842v 12 2 , , PUNCT dv13zs2842v 12 3 the the DET dv13zs2842v 12 4 monovalent monovalent NOUN dv13zs2842v 12 5 phenoxide phenoxide NOUN dv13zs2842v 12 6 - - PUNCT dv13zs2842v 12 7 bridged bridge VERB dv13zs2842v 12 8 zn2bdpa zn2bdpa PUNCT dv13zs2842v 12 9 scaffold scaffold NOUN dv13zs2842v 12 10 is be AUX dv13zs2842v 12 11 a a DET dv13zs2842v 12 12 promising promising ADJ dv13zs2842v 12 13 candidate candidate NOUN dv13zs2842v 12 14 for for ADP dv13zs2842v 12 15 further further ADJ dv13zs2842v 12 16 development development NOUN dv13zs2842v 12 17 as as ADP dv13zs2842v 12 18 a a DET dv13zs2842v 12 19 cell cell NOUN dv13zs2842v 12 20 death death NOUN dv13zs2842v 12 21 imaging image VERB dv13zs2842v 12 22 agent agent NOUN dv13zs2842v 12 23 in in ADP dv13zs2842v 12 24 living living NOUN dv13zs2842v 12 25 subjects subject NOUN dv13zs2842v 12 26 . . PUNCT dv13zs2842v 13 1 in in ADP dv13zs2842v 13 2 chapters chapter NOUN dv13zs2842v 13 3 4 4 NUM dv13zs2842v 13 4 and and CCONJ dv13zs2842v 13 5 5 5 NUM dv13zs2842v 13 6 , , PUNCT dv13zs2842v 13 7 the the DET dv13zs2842v 13 8 focus focus NOUN dv13zs2842v 13 9 moves move VERB dv13zs2842v 13 10 from from ADP dv13zs2842v 13 11 developing develop VERB dv13zs2842v 13 12 affinity affinity NOUN dv13zs2842v 13 13 ligands ligand NOUN dv13zs2842v 13 14 for for ADP dv13zs2842v 13 15 anionic anionic ADJ dv13zs2842v 13 16 lipid lipid NOUN dv13zs2842v 13 17 recognition recognition NOUN dv13zs2842v 13 18 to to ADP dv13zs2842v 13 19 developing develop VERB dv13zs2842v 13 20 molecular molecular ADJ dv13zs2842v 13 21 design design NOUN dv13zs2842v 13 22 principles principle NOUN dv13zs2842v 13 23 for for ADP dv13zs2842v 13 24 liposomal liposomal ADJ dv13zs2842v 13 25 ph ph NOUN dv13zs2842v 13 26 nanosensors nanosensor NOUN dv13zs2842v 13 27 ( ( PUNCT dv13zs2842v 13 28 chapter chapter NOUN dv13zs2842v 13 29 5 5 NUM dv13zs2842v 13 30 ) ) PUNCT dv13zs2842v 13 31 and and CCONJ dv13zs2842v 13 32 new new ADJ dv13zs2842v 13 33 analytical analytical ADJ dv13zs2842v 13 34 strategies strategy NOUN dv13zs2842v 13 35 for for ADP dv13zs2842v 13 36 anion anion NOUN dv13zs2842v 13 37 detection detection NOUN dv13zs2842v 13 38 using use VERB dv13zs2842v 13 39 indicator indicator NOUN dv13zs2842v 13 40 displacement displacement PROPN dv13zs2842v 13 41 assays assays PROPN dv13zs2842v 13 42 ( ( PUNCT dv13zs2842v 13 43 chapter chapter NOUN dv13zs2842v 13 44 6 6 NUM dv13zs2842v 13 45 ) ) PUNCT dv13zs2842v 13 46 . . PUNCT