id sid tid token lemma pos cz30pr78h8x 1 1 plasmodium plasmodium PROPN cz30pr78h8x 1 2 vivax vivax NOUN cz30pr78h8x 1 3 is be AUX cz30pr78h8x 1 4 responsible responsible ADJ cz30pr78h8x 1 5 for for ADP cz30pr78h8x 1 6 70 70 NUM cz30pr78h8x 1 7 - - SYM cz30pr78h8x 1 8 80 80 NUM cz30pr78h8x 1 9 million million NUM cz30pr78h8x 1 10 cases case NOUN cz30pr78h8x 1 11 of of ADP cz30pr78h8x 1 12 malaria malaria NOUN cz30pr78h8x 1 13 annually annually ADV cz30pr78h8x 1 14 and and CCONJ cz30pr78h8x 1 15 has have VERB cz30pr78h8x 1 16 the the DET cz30pr78h8x 1 17 widest wide ADJ cz30pr78h8x 1 18 geographical geographical ADJ cz30pr78h8x 1 19 distribution distribution NOUN cz30pr78h8x 1 20 of of ADP cz30pr78h8x 1 21 the the DET cz30pr78h8x 1 22 human human ADJ cz30pr78h8x 1 23 malaria malaria NOUN cz30pr78h8x 1 24 parasites parasite NOUN cz30pr78h8x 1 25 . . PUNCT cz30pr78h8x 2 1 although although SCONJ cz30pr78h8x 2 2 not not PART cz30pr78h8x 2 3 as as ADV cz30pr78h8x 2 4 deadly deadly ADJ cz30pr78h8x 2 5 as as SCONJ cz30pr78h8x 2 6 the the DET cz30pr78h8x 2 7 human human ADJ cz30pr78h8x 2 8 malaria malaria NOUN cz30pr78h8x 2 9 parasite parasite NOUN cz30pr78h8x 2 10 , , PUNCT cz30pr78h8x 2 11 plasmodium plasmodium NOUN cz30pr78h8x 2 12 falciparum falciparum NOUN cz30pr78h8x 2 13 , , PUNCT cz30pr78h8x 2 14 its its PRON cz30pr78h8x 2 15 widespread widespread ADJ cz30pr78h8x 2 16 distribution distribution NOUN cz30pr78h8x 2 17 and and CCONJ cz30pr78h8x 2 18 the the DET cz30pr78h8x 2 19 lack lack NOUN cz30pr78h8x 2 20 of of ADP cz30pr78h8x 2 21 sustained sustain VERB cz30pr78h8x 2 22 naturally naturally ADV cz30pr78h8x 2 23 acquired acquire VERB cz30pr78h8x 2 24 immunity immunity NOUN cz30pr78h8x 2 25 cause cause SCONJ cz30pr78h8x 2 26 it it PRON cz30pr78h8x 2 27 to to PART cz30pr78h8x 2 28 be be AUX cz30pr78h8x 2 29 a a DET cz30pr78h8x 2 30 very very ADV cz30pr78h8x 2 31 heavy heavy ADJ cz30pr78h8x 2 32 public public ADJ cz30pr78h8x 2 33 health health NOUN cz30pr78h8x 2 34 and and CCONJ cz30pr78h8x 2 35 economic economic ADJ cz30pr78h8x 2 36 burden burden NOUN cz30pr78h8x 2 37 worldwide worldwide ADV cz30pr78h8x 2 38 . . PUNCT cz30pr78h8x 3 1 development development NOUN cz30pr78h8x 3 2 of of ADP cz30pr78h8x 3 3 an an DET cz30pr78h8x 3 4 effective effective ADJ cz30pr78h8x 3 5 vaccine vaccine NOUN cz30pr78h8x 3 6 against against ADP cz30pr78h8x 3 7 this this DET cz30pr78h8x 3 8 parasite parasite NOUN cz30pr78h8x 3 9 is be AUX cz30pr78h8x 3 10 a a DET cz30pr78h8x 3 11 public public ADJ cz30pr78h8x 3 12 health health NOUN cz30pr78h8x 3 13 imperative imperative NOUN cz30pr78h8x 3 14 . . PUNCT cz30pr78h8x 4 1 clinical clinical ADJ cz30pr78h8x 4 2 symptoms symptom NOUN cz30pr78h8x 4 3 of of ADP cz30pr78h8x 4 4 malaria malaria NOUN cz30pr78h8x 4 5 are be AUX cz30pr78h8x 4 6 caused cause VERB cz30pr78h8x 4 7 by by ADP cz30pr78h8x 4 8 the the DET cz30pr78h8x 4 9 blood blood NOUN cz30pr78h8x 4 10 stage stage NOUN cz30pr78h8x 4 11 of of ADP cz30pr78h8x 4 12 the the DET cz30pr78h8x 4 13 disease disease NOUN cz30pr78h8x 4 14 in in ADP cz30pr78h8x 4 15 which which PRON cz30pr78h8x 4 16 the the DET cz30pr78h8x 4 17 parasites parasite NOUN cz30pr78h8x 4 18 invade invade VERB cz30pr78h8x 4 19 red red ADJ cz30pr78h8x 4 20 blood blood NOUN cz30pr78h8x 4 21 cells cell NOUN cz30pr78h8x 4 22 , , PUNCT cz30pr78h8x 4 23 replicate replicate VERB cz30pr78h8x 4 24 inside inside ADP cz30pr78h8x 4 25 them they PRON cz30pr78h8x 4 26 and and CCONJ cz30pr78h8x 4 27 then then ADV cz30pr78h8x 4 28 are be AUX cz30pr78h8x 4 29 released release VERB cz30pr78h8x 4 30 into into ADP cz30pr78h8x 4 31 the the DET cz30pr78h8x 4 32 circulation circulation NOUN cz30pr78h8x 4 33 to to PART cz30pr78h8x 4 34 invade invade VERB cz30pr78h8x 4 35 new new ADJ cz30pr78h8x 4 36 red red ADJ cz30pr78h8x 4 37 blood blood NOUN cz30pr78h8x 4 38 cells cell NOUN cz30pr78h8x 4 39 . . PUNCT cz30pr78h8x 5 1 this this DET cz30pr78h8x 5 2 process process NOUN cz30pr78h8x 5 3 results result VERB cz30pr78h8x 5 4 in in ADP cz30pr78h8x 5 5 the the DET cz30pr78h8x 5 6 destruction destruction NOUN cz30pr78h8x 5 7 of of ADP cz30pr78h8x 5 8 large large ADJ cz30pr78h8x 5 9 numbers number NOUN cz30pr78h8x 5 10 of of ADP cz30pr78h8x 5 11 red red ADJ cz30pr78h8x 5 12 blood blood NOUN cz30pr78h8x 5 13 cells cell NOUN cz30pr78h8x 5 14 causing cause VERB cz30pr78h8x 5 15 fever fever NOUN cz30pr78h8x 5 16 and and CCONJ cz30pr78h8x 5 17 chills chill NOUN cz30pr78h8x 5 18 and and CCONJ cz30pr78h8x 5 19 severe severe ADJ cz30pr78h8x 5 20 anemia anemia NOUN cz30pr78h8x 5 21 among among ADP cz30pr78h8x 5 22 other other ADJ cz30pr78h8x 5 23 symptoms symptom NOUN cz30pr78h8x 5 24 . . PUNCT cz30pr78h8x 6 1 the the DET cz30pr78h8x 6 2 invasion invasion NOUN cz30pr78h8x 6 3 process process NOUN cz30pr78h8x 6 4 is be AUX cz30pr78h8x 6 5 reliant reliant ADJ cz30pr78h8x 6 6 upon upon SCONJ cz30pr78h8x 6 7 specific specific ADJ cz30pr78h8x 6 8 interactions interaction NOUN cz30pr78h8x 6 9 between between ADP cz30pr78h8x 6 10 parasite parasite NOUN cz30pr78h8x 6 11 ligands ligand NOUN cz30pr78h8x 6 12 and and CCONJ cz30pr78h8x 6 13 host host NOUN cz30pr78h8x 6 14 cell cell NOUN cz30pr78h8x 6 15 receptors receptor NOUN cz30pr78h8x 6 16 . . PUNCT cz30pr78h8x 7 1 in in ADP cz30pr78h8x 7 2 the the DET cz30pr78h8x 7 3 p. p. PROPN cz30pr78h8x 7 4 vivax vivax PROPN cz30pr78h8x 7 5 , , PUNCT cz30pr78h8x 7 6 the the DET cz30pr78h8x 7 7 interaction interaction NOUN cz30pr78h8x 7 8 between between ADP cz30pr78h8x 7 9 the the DET cz30pr78h8x 7 10 parasite parasite NOUN cz30pr78h8x 7 11 duffy duffy NOUN cz30pr78h8x 7 12 binding bind VERB cz30pr78h8x 7 13 protein protein NOUN cz30pr78h8x 7 14 ( ( PUNCT cz30pr78h8x 7 15 pvdbp pvdbp NOUN cz30pr78h8x 7 16 ) ) PUNCT cz30pr78h8x 7 17 and and CCONJ cz30pr78h8x 7 18 the the DET cz30pr78h8x 7 19 host host NOUN cz30pr78h8x 7 20 duffy duffy PROPN cz30pr78h8x 7 21 antigen antigen PROPN cz30pr78h8x 7 22 / / SYM cz30pr78h8x 7 23 receptor receptor NOUN cz30pr78h8x 7 24 for for ADP cz30pr78h8x 7 25 chemokines chemokine NOUN cz30pr78h8x 7 26 ( ( PUNCT cz30pr78h8x 7 27 darc darc X cz30pr78h8x 7 28 ) ) PUNCT cz30pr78h8x 7 29 is be AUX cz30pr78h8x 7 30 absolutely absolutely ADV cz30pr78h8x 7 31 required require VERB cz30pr78h8x 7 32 for for ADP cz30pr78h8x 7 33 invasion invasion NOUN cz30pr78h8x 7 34 . . PUNCT cz30pr78h8x 8 1 individuals individual NOUN cz30pr78h8x 8 2 who who PRON cz30pr78h8x 8 3 lack lack VERB cz30pr78h8x 8 4 darc darc ADJ cz30pr78h8x 8 5 are be AUX cz30pr78h8x 8 6 completely completely ADV cz30pr78h8x 8 7 protected protect VERB cz30pr78h8x 8 8 from from ADP cz30pr78h8x 8 9 blood blood NOUN cz30pr78h8x 8 10 stage stage NOUN cz30pr78h8x 8 11 infection infection NOUN cz30pr78h8x 8 12 and and CCONJ cz30pr78h8x 8 13 therefore therefore ADV cz30pr78h8x 8 14 , , PUNCT cz30pr78h8x 8 15 clinical clinical ADJ cz30pr78h8x 8 16 disease disease NOUN cz30pr78h8x 8 17 . . PUNCT cz30pr78h8x 9 1 pvdbp pvdbp NOUN cz30pr78h8x 9 2 is be AUX cz30pr78h8x 9 3 , , PUNCT cz30pr78h8x 9 4 therefore therefore ADV cz30pr78h8x 9 5 , , PUNCT cz30pr78h8x 9 6 a a DET cz30pr78h8x 9 7 very very ADV cz30pr78h8x 9 8 attractive attractive ADJ cz30pr78h8x 9 9 vaccine vaccine NOUN cz30pr78h8x 9 10 candidate candidate NOUN cz30pr78h8x 9 11 . . PUNCT cz30pr78h8x 10 1 pvdbp pvdbp NOUN cz30pr78h8x 10 2 is be AUX cz30pr78h8x 10 3 a a DET cz30pr78h8x 10 4 highly highly ADV cz30pr78h8x 10 5 polymorphic polymorphic ADJ cz30pr78h8x 10 6 protein protein NOUN cz30pr78h8x 10 7 , , PUNCT cz30pr78h8x 10 8 complicating complicating ADJ cz30pr78h8x 10 9 vaccine vaccine NOUN cz30pr78h8x 10 10 development development NOUN cz30pr78h8x 10 11 . . PUNCT cz30pr78h8x 11 1 understanding understanding NOUN cz30pr78h8x 11 2 of of ADP cz30pr78h8x 11 3 the the DET cz30pr78h8x 11 4 role role NOUN cz30pr78h8x 11 5 of of ADP cz30pr78h8x 11 6 these these DET cz30pr78h8x 11 7 polymorphisms polymorphism NOUN cz30pr78h8x 11 8 in in ADP cz30pr78h8x 11 9 determining determine VERB cz30pr78h8x 11 10 strain strain NOUN cz30pr78h8x 11 11 - - PUNCT cz30pr78h8x 11 12 specific specific ADJ cz30pr78h8x 11 13 immune immune ADJ cz30pr78h8x 11 14 responses response NOUN cz30pr78h8x 11 15 and and CCONJ cz30pr78h8x 11 16 determination determination NOUN cz30pr78h8x 11 17 of of ADP cz30pr78h8x 11 18 residues residue NOUN cz30pr78h8x 11 19 that that PRON cz30pr78h8x 11 20 form form NOUN cz30pr78h8x 11 21 conserved conserve VERB cz30pr78h8x 11 22 epitopes epitope NOUN cz30pr78h8x 11 23 will will AUX cz30pr78h8x 11 24 be be AUX cz30pr78h8x 11 25 vital vital ADJ cz30pr78h8x 11 26 for for ADP cz30pr78h8x 11 27 successful successful ADJ cz30pr78h8x 11 28 development development NOUN cz30pr78h8x 11 29 of of ADP cz30pr78h8x 11 30 a a DET cz30pr78h8x 11 31 strain strain NOUN cz30pr78h8x 11 32 - - PUNCT cz30pr78h8x 11 33 transcending transcend VERB cz30pr78h8x 11 34 vaccine vaccine NOUN cz30pr78h8x 11 35 . . PUNCT cz30pr78h8x 12 1 we we PRON cz30pr78h8x 12 2 examined examine VERB cz30pr78h8x 12 3 the the DET cz30pr78h8x 12 4 basis basis NOUN cz30pr78h8x 12 5 for for SCONJ cz30pr78h8x 12 6 a a DET cz30pr78h8x 12 7 limited limited ADJ cz30pr78h8x 12 8 polymorphisms polymorphism NOUN cz30pr78h8x 12 9 n417k n417k ADJ cz30pr78h8x 12 10 and and CCONJ cz30pr78h8x 12 11 found find VERB cz30pr78h8x 12 12 that that SCONJ cz30pr78h8x 12 13 a a DET cz30pr78h8x 12 14 number number NOUN cz30pr78h8x 12 15 of of ADP cz30pr78h8x 12 16 amino amino NOUN cz30pr78h8x 12 17 acid acid NOUN cz30pr78h8x 12 18 substitutions substitution NOUN cz30pr78h8x 12 19 are be AUX cz30pr78h8x 12 20 excluded exclude VERB cz30pr78h8x 12 21 from from ADP cz30pr78h8x 12 22 natural natural ADJ cz30pr78h8x 12 23 isolates isolate NOUN cz30pr78h8x 12 24 because because SCONJ cz30pr78h8x 12 25 of of ADP cz30pr78h8x 12 26 their their PRON cz30pr78h8x 12 27 poor poor ADJ cz30pr78h8x 12 28 binding binding ADJ cz30pr78h8x 12 29 phenotypes phenotype NOUN cz30pr78h8x 12 30 and and CCONJ cz30pr78h8x 12 31 that that SCONJ cz30pr78h8x 12 32 the the DET cz30pr78h8x 12 33 naturally naturally ADV cz30pr78h8x 12 34 occurring occur VERB cz30pr78h8x 12 35 residues residue NOUN cz30pr78h8x 12 36 n n ADV cz30pr78h8x 12 37 and and CCONJ cz30pr78h8x 12 38 k k PROPN cz30pr78h8x 12 39 are be AUX cz30pr78h8x 12 40 the the DET cz30pr78h8x 12 41 most most ADV cz30pr78h8x 12 42 antigenically antigenically ADV cz30pr78h8x 12 43 distinct distinct ADJ cz30pr78h8x 12 44 . . PUNCT cz30pr78h8x 13 1 we we PRON cz30pr78h8x 13 2 also also ADV cz30pr78h8x 13 3 created create VERB cz30pr78h8x 13 4 a a DET cz30pr78h8x 13 5 panel panel NOUN cz30pr78h8x 13 6 of of ADP cz30pr78h8x 13 7 pvdbp pvdbp NOUN cz30pr78h8x 13 8 variants variant NOUN cz30pr78h8x 13 9 representative representative NOUN cz30pr78h8x 13 10 of of ADP cz30pr78h8x 13 11 global global ADJ cz30pr78h8x 13 12 genetic genetic ADJ cz30pr78h8x 13 13 diversity diversity NOUN cz30pr78h8x 13 14 and and CCONJ cz30pr78h8x 13 15 examined examine VERB cz30pr78h8x 13 16 their their PRON cz30pr78h8x 13 17 responses response NOUN cz30pr78h8x 13 18 to to ADP cz30pr78h8x 13 19 immune immune ADJ cz30pr78h8x 13 20 inhibition inhibition NOUN cz30pr78h8x 13 21 , , PUNCT cz30pr78h8x 13 22 demonstrating demonstrate VERB cz30pr78h8x 13 23 that that SCONJ cz30pr78h8x 13 24 they they PRON cz30pr78h8x 13 25 show show VERB cz30pr78h8x 13 26 strain strain NOUN cz30pr78h8x 13 27 - - PUNCT cz30pr78h8x 13 28 specific specific ADJ cz30pr78h8x 13 29 responses response NOUN cz30pr78h8x 13 30 . . PUNCT cz30pr78h8x 14 1 furthermore furthermore ADV cz30pr78h8x 14 2 , , PUNCT cz30pr78h8x 14 3 we we PRON cz30pr78h8x 14 4 compared compare VERB cz30pr78h8x 14 5 pvdbp pvdbp NOUN cz30pr78h8x 14 6 to to ADP cz30pr78h8x 14 7 a a DET cz30pr78h8x 14 8 dbp dbp NOUN cz30pr78h8x 14 9 from from ADP cz30pr78h8x 14 10 plasmodium plasmodium NOUN cz30pr78h8x 14 11 knowlesi knowlesi NOUN cz30pr78h8x 14 12 , , PUNCT cz30pr78h8x 14 13 pkì_å pkì_å SPACE cz30pr78h8x 14 14 _ _ PRON cz30pr78h8x 14 15 , , PUNCT cz30pr78h8x 14 16 to to PART cz30pr78h8x 14 17 determine determine VERB cz30pr78h8x 14 18 the the DET cz30pr78h8x 14 19 molecular molecular ADJ cz30pr78h8x 14 20 basis basis NOUN cz30pr78h8x 14 21 for for ADP cz30pr78h8x 14 22 their their PRON cz30pr78h8x 14 23 host host NOUN cz30pr78h8x 14 24 - - PUNCT cz30pr78h8x 14 25 specific specific ADJ cz30pr78h8x 14 26 invasion invasion NOUN cz30pr78h8x 14 27 phenotypes phenotype NOUN cz30pr78h8x 14 28 . . PUNCT cz30pr78h8x 15 1 we we PRON cz30pr78h8x 15 2 also also ADV cz30pr78h8x 15 3 validated validate VERB cz30pr78h8x 15 4 a a DET cz30pr78h8x 15 5 primate primate ADJ cz30pr78h8x 15 6 model model NOUN cz30pr78h8x 15 7 for for ADP cz30pr78h8x 15 8 use use NOUN cz30pr78h8x 15 9 in in ADP cz30pr78h8x 15 10 vaccine vaccine NOUN cz30pr78h8x 15 11 testing testing NOUN cz30pr78h8x 15 12 , , PUNCT cz30pr78h8x 15 13 demonstrating demonstrate VERB cz30pr78h8x 15 14 that that DET cz30pr78h8x 15 15 invasion invasion NOUN cz30pr78h8x 15 16 of of ADP cz30pr78h8x 15 17 aotus aotus PROPN cz30pr78h8x 15 18 nancymai nancymai PROPN cz30pr78h8x 15 19 erythrocytes erythrocyte NOUN cz30pr78h8x 15 20 by by ADP cz30pr78h8x 15 21 pvdbp pvdbp NOUN cz30pr78h8x 15 22 is be AUX cz30pr78h8x 15 23 duffy duffy ADJ cz30pr78h8x 15 24 antigen antigen NOUN cz30pr78h8x 15 25 dependent dependent ADJ cz30pr78h8x 15 26 . . PUNCT