id	sid	tid	token	lemma	pos
c247dr29r9d	1	1	the	the	DET
c247dr29r9d	1	2	communication	communication	NOUN
c247dr29r9d	1	3	between	between	ADP
c247dr29r9d	1	4	cancer	cancer	NOUN
c247dr29r9d	1	5	cells	cell	NOUN
c247dr29r9d	1	6	and	and	CCONJ
c247dr29r9d	1	7	the	the	DET
c247dr29r9d	1	8	tumor	tumor	NOUN
c247dr29r9d	1	9	microenvironments	microenvironment	NOUN
c247dr29r9d	1	10	is	be	AUX
c247dr29r9d	1	11	critical	critical	ADJ
c247dr29r9d	1	12	for	for	ADP
c247dr29r9d	1	13	metastasis	metastasis	NOUN
c247dr29r9d	1	14	.	.	PUNCT
c247dr29r9d	2	1	emerging	emerge	VERB
c247dr29r9d	2	2	evidence	evidence	NOUN
c247dr29r9d	2	3	indicates	indicate	VERB
c247dr29r9d	2	4	that	that	SCONJ
c247dr29r9d	2	5	tumor	tumor	NOUN
c247dr29r9d	2	6	-	-	PUNCT
c247dr29r9d	2	7	derived	derive	VERB
c247dr29r9d	2	8	extracellular	extracellular	ADJ
c247dr29r9d	2	9	vesicles	vesicle	NOUN
c247dr29r9d	2	10	play	play	VERB
c247dr29r9d	2	11	an	an	DET
c247dr29r9d	2	12	important	important	ADJ
c247dr29r9d	2	13	role	role	NOUN
c247dr29r9d	2	14	in	in	ADP
c247dr29r9d	2	15	mediating	mediate	VERB
c247dr29r9d	2	16	such	such	ADJ
c247dr29r9d	2	17	intercommunication	intercommunication	NOUN
c247dr29r9d	2	18	by	by	ADP
c247dr29r9d	2	19	intercellular	intercellular	ADJ
c247dr29r9d	2	20	transport	transport	NOUN
c247dr29r9d	2	21	of	of	ADP
c247dr29r9d	2	22	bioactive	bioactive	ADJ
c247dr29r9d	2	23	materials	material	NOUN
c247dr29r9d	2	24	.	.	PUNCT
c247dr29r9d	3	1	accumulating	accumulate	VERB
c247dr29r9d	3	2	evidence	evidence	NOUN
c247dr29r9d	3	3	has	have	AUX
c247dr29r9d	3	4	shown	show	VERB
c247dr29r9d	3	5	that	that	SCONJ
c247dr29r9d	3	6	the	the	DET
c247dr29r9d	3	7	aberrant	aberrant	ADJ
c247dr29r9d	3	8	release	release	NOUN
c247dr29r9d	3	9	of	of	ADP
c247dr29r9d	3	10	tumor	tumor	NOUN
c247dr29r9d	3	11	-	-	PUNCT
c247dr29r9d	3	12	derived	derive	VERB
c247dr29r9d	3	13	microvesicles	microvesicle	NOUN
c247dr29r9d	3	14	(	(	PUNCT
c247dr29r9d	3	15	tmvs	tmvs	PROPN
c247dr29r9d	3	16	)	)	PUNCT
c247dr29r9d	3	17	,	,	PUNCT
c247dr29r9d	3	18	a	a	DET
c247dr29r9d	3	19	subtype	subtype	NOUN
c247dr29r9d	3	20	of	of	ADP
c247dr29r9d	3	21	extracellular	extracellular	ADJ
c247dr29r9d	3	22	vesicles	vesicle	NOUN
c247dr29r9d	3	23	released	release	VERB
c247dr29r9d	3	24	by	by	ADP
c247dr29r9d	3	25	tumor	tumor	NOUN
c247dr29r9d	3	26	cells	cell	NOUN
c247dr29r9d	3	27	,	,	PUNCT
c247dr29r9d	3	28	correlates	correlate	VERB
c247dr29r9d	3	29	with	with	ADP
c247dr29r9d	3	30	the	the	DET
c247dr29r9d	3	31	onset	onset	NOUN
c247dr29r9d	3	32	and	and	CCONJ
c247dr29r9d	3	33	progression	progression	NOUN
c247dr29r9d	3	34	of	of	ADP
c247dr29r9d	3	35	cancers	cancer	NOUN
c247dr29r9d	3	36	.	.	PUNCT
c247dr29r9d	4	1	this	this	DET
c247dr29r9d	4	2	study	study	NOUN
c247dr29r9d	4	3	investigated	investigate	VERB
c247dr29r9d	4	4	the	the	DET
c247dr29r9d	4	5	mirna	mirna	PROPN
c247dr29r9d	4	6	content	content	NOUN
c247dr29r9d	4	7	of	of	ADP
c247dr29r9d	4	8	tmvs	tmvs	PROPN
c247dr29r9d	4	9	and	and	CCONJ
c247dr29r9d	4	10	delineated	delineate	VERB
c247dr29r9d	4	11	a	a	DET
c247dr29r9d	4	12	mechanism	mechanism	NOUN
c247dr29r9d	4	13	through	through	ADP
c247dr29r9d	4	14	which	which	PRON
c247dr29r9d	4	15	active	active	ADJ
c247dr29r9d	4	16	arf6	arf6	PROPN
c247dr29r9d	4	17	promotes	promote	VERB
c247dr29r9d	4	18	mirna	mirna	PROPN
c247dr29r9d	4	19	abundance	abundance	NOUN
c247dr29r9d	4	20	in	in	ADP
c247dr29r9d	4	21	tmvs.first	tmvs.first	PROPN
c247dr29r9d	4	22	,	,	PUNCT
c247dr29r9d	4	23	the	the	DET
c247dr29r9d	4	24	mirna	mirna	PROPN
c247dr29r9d	4	25	content	content	NOUN
c247dr29r9d	4	26	in	in	ADP
c247dr29r9d	4	27	tmvs	tmvs	PROPN
c247dr29r9d	4	28	shed	shed	VERB
c247dr29r9d	4	29	from	from	ADP
c247dr29r9d	4	30	melanoma	melanoma	ADJ
c247dr29r9d	4	31	cells	cell	NOUN
c247dr29r9d	4	32	was	be	AUX
c247dr29r9d	4	33	characterized	characterize	VERB
c247dr29r9d	4	34	.	.	PUNCT
c247dr29r9d	5	1	a	a	DET
c247dr29r9d	5	2	small	small	ADJ
c247dr29r9d	5	3	set	set	NOUN
c247dr29r9d	5	4	of	of	ADP
c247dr29r9d	5	5	mirnas	mirna	NOUN
c247dr29r9d	5	6	was	be	AUX
c247dr29r9d	5	7	selectively	selectively	ADV
c247dr29r9d	5	8	enriched	enrich	VERB
c247dr29r9d	5	9	in	in	ADP
c247dr29r9d	5	10	tmvs	tmvs	PROPN
c247dr29r9d	5	11	,	,	PUNCT
c247dr29r9d	5	12	although	although	SCONJ
c247dr29r9d	5	13	tmv	tmv	ADJ
c247dr29r9d	5	14	mirna	mirna	PROPN
c247dr29r9d	5	15	profiles	profile	NOUN
c247dr29r9d	5	16	are	be	AUX
c247dr29r9d	5	17	representative	representative	ADJ
c247dr29r9d	5	18	of	of	ADP
c247dr29r9d	5	19	the	the	DET
c247dr29r9d	5	20	mirna	mirna	PROPN
c247dr29r9d	5	21	profiles	profile	NOUN
c247dr29r9d	5	22	of	of	ADP
c247dr29r9d	5	23	their	their	PRON
c247dr29r9d	5	24	cells	cell	NOUN
c247dr29r9d	5	25	of	of	ADP
c247dr29r9d	5	26	origin	origin	NOUN
c247dr29r9d	5	27	.	.	PUNCT
c247dr29r9d	6	1	in	in	ADP
c247dr29r9d	6	2	addition	addition	NOUN
c247dr29r9d	6	3	,	,	PUNCT
c247dr29r9d	6	4	the	the	DET
c247dr29r9d	6	5	data	datum	NOUN
c247dr29r9d	6	6	presented	present	VERB
c247dr29r9d	6	7	here	here	ADV
c247dr29r9d	6	8	indicated	indicate	VERB
c247dr29r9d	6	9	that	that	SCONJ
c247dr29r9d	6	10	tmv	tmv	PROPN
c247dr29r9d	6	11	mir-21	mir-21	PROPN
c247dr29r9d	6	12	plays	play	VERB
c247dr29r9d	6	13	a	a	DET
c247dr29r9d	6	14	central	central	ADJ
c247dr29r9d	6	15	role	role	NOUN
c247dr29r9d	6	16	in	in	ADP
c247dr29r9d	6	17	promoting	promote	VERB
c247dr29r9d	6	18	cell	cell	NOUN
c247dr29r9d	6	19	invasion	invasion	NOUN
c247dr29r9d	6	20	in	in	ADP
c247dr29r9d	6	21	recipient	recipient	ADJ
c247dr29r9d	6	22	tumor	tumor	NOUN
c247dr29r9d	6	23	cells	cell	NOUN
c247dr29r9d	6	24	.	.	PUNCT
c247dr29r9d	7	1	we	we	PRON
c247dr29r9d	7	2	also	also	ADV
c247dr29r9d	7	3	demonstrate	demonstrate	VERB
c247dr29r9d	7	4	that	that	SCONJ
c247dr29r9d	7	5	there	there	PRON
c247dr29r9d	7	6	is	be	VERB
c247dr29r9d	7	7	a	a	DET
c247dr29r9d	7	8	set	set	NOUN
c247dr29r9d	7	9	of	of	ADP
c247dr29r9d	7	10	mirnas	mirna	NOUN
c247dr29r9d	7	11	enriched	enrich	VERB
c247dr29r9d	7	12	in	in	ADP
c247dr29r9d	7	13	tmvs	tmvs	PROPN
c247dr29r9d	7	14	shed	shed	VERB
c247dr29r9d	7	15	from	from	ADP
c247dr29r9d	7	16	breast	breast	NOUN
c247dr29r9d	7	17	,	,	PUNCT
c247dr29r9d	7	18	melanoma	melanoma	ADJ
c247dr29r9d	7	19	,	,	PUNCT
c247dr29r9d	7	20	and	and	CCONJ
c247dr29r9d	7	21	prostate	prostate	NOUN
c247dr29r9d	7	22	cancer	cancer	NOUN
c247dr29r9d	7	23	cell	cell	NOUN
c247dr29r9d	7	24	lines	line	NOUN
c247dr29r9d	7	25	,	,	PUNCT
c247dr29r9d	7	26	that	that	PRON
c247dr29r9d	7	27	may	may	AUX
c247dr29r9d	7	28	represent	represent	VERB
c247dr29r9d	7	29	a	a	DET
c247dr29r9d	7	30	prototype	prototype	NOUN
c247dr29r9d	7	31	of	of	ADP
c247dr29r9d	7	32	a	a	DET
c247dr29r9d	7	33	potential	potential	ADJ
c247dr29r9d	7	34	general	general	ADJ
c247dr29r9d	7	35	mirna	mirna	PROPN
c247dr29r9d	7	36	signature	signature	NOUN
c247dr29r9d	7	37	.	.	PUNCT
c247dr29r9d	8	1	moreover	moreover	ADV
c247dr29r9d	8	2	,	,	PUNCT
c247dr29r9d	8	3	our	our	PRON
c247dr29r9d	8	4	data	datum	NOUN
c247dr29r9d	8	5	indicated	indicate	VERB
c247dr29r9d	8	6	that	that	SCONJ
c247dr29r9d	8	7	the	the	DET
c247dr29r9d	8	8	signature	signature	NOUN
c247dr29r9d	8	9	mirnas	mirnas	PROPN
c247dr29r9d	8	10	have	have	VERB
c247dr29r9d	8	11	a	a	DET
c247dr29r9d	8	12	guanine	guanine	NOUN
c247dr29r9d	8	13	-	-	PUNCT
c247dr29r9d	8	14	rich	rich	ADJ
c247dr29r9d	8	15	motif.previous	motif.previous	ADJ
c247dr29r9d	8	16	research	research	NOUN
c247dr29r9d	8	17	has	have	AUX
c247dr29r9d	8	18	shown	show	VERB
c247dr29r9d	8	19	that	that	SCONJ
c247dr29r9d	8	20	arf6	arf6	PROPN
c247dr29r9d	8	21	activation	activation	NOUN
c247dr29r9d	8	22	promotes	promote	VERB
c247dr29r9d	8	23	the	the	DET
c247dr29r9d	8	24	shedding	shedding	NOUN
c247dr29r9d	8	25	of	of	ADP
c247dr29r9d	8	26	tmvs	tmvs	PROPN
c247dr29r9d	8	27	.	.	PUNCT
c247dr29r9d	9	1	here	here	ADV
c247dr29r9d	9	2	we	we	PRON
c247dr29r9d	9	3	showed	show	VERB
c247dr29r9d	9	4	a	a	DET
c247dr29r9d	9	5	mechanism	mechanism	NOUN
c247dr29r9d	9	6	through	through	ADP
c247dr29r9d	9	7	which	which	PRON
c247dr29r9d	9	8	arf6	arf6	PROPN
c247dr29r9d	9	9	regulates	regulate	VERB
c247dr29r9d	9	10	the	the	DET
c247dr29r9d	9	11	trafficking	trafficking	NOUN
c247dr29r9d	9	12	of	of	ADP
c247dr29r9d	9	13	pre	pre	ADJ
c247dr29r9d	9	14	-	-	NOUN
c247dr29r9d	9	15	mirnas	mirna	NOUN
c247dr29r9d	9	16	to	to	ADP
c247dr29r9d	9	17	tmvs	tmvs	PROPN
c247dr29r9d	9	18	.	.	PUNCT
c247dr29r9d	10	1	this	this	PRON
c247dr29r9d	10	2	is	be	AUX
c247dr29r9d	10	3	facilitated	facilitate	VERB
c247dr29r9d	10	4	by	by	ADP
c247dr29r9d	10	5	formation	formation	NOUN
c247dr29r9d	10	6	of	of	ADP
c247dr29r9d	10	7	a	a	DET
c247dr29r9d	10	8	complex	complex	ADJ
c247dr29r9d	10	9	consisting	consist	VERB
c247dr29r9d	10	10	of	of	ADP
c247dr29r9d	10	11	pre	pre	ADJ
c247dr29r9d	10	12	-	-	ADJ
c247dr29r9d	10	13	mirna	mirna	ADJ
c247dr29r9d	10	14	,	,	PUNCT
c247dr29r9d	10	15	arf6	arf6	PROPN
c247dr29r9d	10	16	-	-	PUNCT
c247dr29r9d	10	17	gtp	gtp	PROPN
c247dr29r9d	10	18	,	,	PUNCT
c247dr29r9d	10	19	exportin-5	exportin-5	PROPN
c247dr29r9d	10	20	(	(	PUNCT
c247dr29r9d	10	21	xpo5	xpo5	PROPN
c247dr29r9d	10	22	)	)	PUNCT
c247dr29r9d	10	23	,	,	PUNCT
c247dr29r9d	10	24	and	and	CCONJ
c247dr29r9d	10	25	cytohesin-3	cytohesin-3	PROPN
c247dr29r9d	10	26	(	(	PUNCT
c247dr29r9d	10	27	grp1	grp1	PROPN
c247dr29r9d	10	28	)	)	PUNCT
c247dr29r9d	10	29	.	.	PUNCT
c247dr29r9d	11	1	disruption	disruption	NOUN
c247dr29r9d	11	2	of	of	ADP
c247dr29r9d	11	3	this	this	DET
c247dr29r9d	11	4	complex	complex	ADJ
c247dr29r9d	11	5	results	result	NOUN
c247dr29r9d	11	6	in	in	ADP
c247dr29r9d	11	7	the	the	DET
c247dr29r9d	11	8	release	release	NOUN
c247dr29r9d	11	9	of	of	ADP
c247dr29r9d	11	10	tmvs	tmv	NOUN
c247dr29r9d	11	11	lacking	lack	VERB
c247dr29r9d	11	12	pre	pre	ADJ
c247dr29r9d	11	13	-	-	ADJ
c247dr29r9d	11	14	mirna	mirna	ADJ
c247dr29r9d	11	15	and	and	CCONJ
c247dr29r9d	11	16	mature	mature	VERB
c247dr29r9d	11	17	mirnas	mirna	NOUN
c247dr29r9d	11	18	.	.	PUNCT
c247dr29r9d	12	1	additionally	additionally	ADV
c247dr29r9d	12	2	,	,	PUNCT
c247dr29r9d	12	3	we	we	PRON
c247dr29r9d	12	4	demonstrated	demonstrate	VERB
c247dr29r9d	12	5	that	that	SCONJ
c247dr29r9d	12	6	grp1	grp1	PROPN
c247dr29r9d	12	7	serves	serve	VERB
c247dr29r9d	12	8	as	as	ADP
c247dr29r9d	12	9	a	a	DET
c247dr29r9d	12	10	scaffolding	scaffold	VERB
c247dr29r9d	12	11	protein	protein	NOUN
c247dr29r9d	12	12	and	and	CCONJ
c247dr29r9d	12	13	its	its	PRON
c247dr29r9d	12	14	depletion	depletion	NOUN
c247dr29r9d	12	15	disrupts	disrupt	VERB
c247dr29r9d	12	16	the	the	DET
c247dr29r9d	12	17	formation	formation	NOUN
c247dr29r9d	12	18	and	and	CCONJ
c247dr29r9d	12	19	trafficking	trafficking	NOUN
c247dr29r9d	12	20	of	of	ADP
c247dr29r9d	12	21	the	the	DET
c247dr29r9d	12	22	complex	complex	NOUN
c247dr29r9d	12	23	.	.	PUNCT
c247dr29r9d	13	1	finally	finally	ADV
c247dr29r9d	13	2	,	,	PUNCT
c247dr29r9d	13	3	by	by	ADP
c247dr29r9d	13	4	interrogating	interrogate	VERB
c247dr29r9d	13	5	the	the	DET
c247dr29r9d	13	6	cancer	cancer	NOUN
c247dr29r9d	13	7	genome	genome	NOUN
c247dr29r9d	13	8	atlas	atlas	NOUN
c247dr29r9d	13	9	database	database	NOUN
c247dr29r9d	13	10	,	,	PUNCT
c247dr29r9d	13	11	we	we	PRON
c247dr29r9d	13	12	showed	show	VERB
c247dr29r9d	13	13	that	that	SCONJ
c247dr29r9d	13	14	grp1	grp1	PROPN
c247dr29r9d	13	15	expression	expression	NOUN
c247dr29r9d	13	16	negatively	negatively	ADV
c247dr29r9d	13	17	correlates	correlate	VERB
c247dr29r9d	13	18	with	with	ADP
c247dr29r9d	13	19	poor	poor	ADJ
c247dr29r9d	13	20	prognosis	prognosis	NOUN
c247dr29r9d	13	21	for	for	ADP
c247dr29r9d	13	22	breast	breast	NOUN
c247dr29r9d	13	23	,	,	PUNCT
c247dr29r9d	13	24	colorectal	colorectal	ADJ
c247dr29r9d	13	25	,	,	PUNCT
c247dr29r9d	13	26	melanoma	melanoma	ADJ
c247dr29r9d	13	27	,	,	PUNCT
c247dr29r9d	13	28	and	and	CCONJ
c247dr29r9d	13	29	ovarian	ovarian	ADJ
c247dr29r9d	13	30	cancer	cancer	NOUN
c247dr29r9d	13	31	patients	patient	NOUN
c247dr29r9d	13	32	.	.	PUNCT
c247dr29r9d	14	1	together	together	ADV
c247dr29r9d	14	2	,	,	PUNCT
c247dr29r9d	14	3	these	these	DET
c247dr29r9d	14	4	studies	study	NOUN
c247dr29r9d	14	5	suggest	suggest	VERB
c247dr29r9d	14	6	that	that	SCONJ
c247dr29r9d	14	7	tmv	tmv	PROPN
c247dr29r9d	14	8	mirna	mirna	PROPN
c247dr29r9d	14	9	holds	hold	VERB
c247dr29r9d	14	10	great	great	ADJ
c247dr29r9d	14	11	potential	potential	NOUN
c247dr29r9d	14	12	to	to	PART
c247dr29r9d	14	13	be	be	AUX
c247dr29r9d	14	14	used	use	VERB
c247dr29r9d	14	15	as	as	ADP
c247dr29r9d	14	16	biomarkers	biomarker	NOUN
c247dr29r9d	14	17	for	for	ADP
c247dr29r9d	14	18	cancer	cancer	NOUN
c247dr29r9d	14	19	diagnosis	diagnosis	NOUN
c247dr29r9d	14	20	and	and	CCONJ
c247dr29r9d	14	21	the	the	DET
c247dr29r9d	14	22	mirna	mirna	PROPN
c247dr29r9d	14	23	trafficking	trafficking	NOUN
c247dr29r9d	14	24	regulators	regulator	NOUN
c247dr29r9d	14	25	such	such	ADJ
c247dr29r9d	14	26	as	as	SCONJ
c247dr29r9d	14	27	grp1	grp1	PROPN
c247dr29r9d	14	28	is	be	AUX
c247dr29r9d	14	29	a	a	DET
c247dr29r9d	14	30	prospective	prospective	ADJ
c247dr29r9d	14	31	therapeutic	therapeutic	ADJ
c247dr29r9d	14	32	target	target	NOUN
c247dr29r9d	14	33	.	.	PUNCT