id sid tid token lemma pos bn999595x0b 1 1 oxygen oxygen NOUN bn999595x0b 1 2 provision provision NOUN bn999595x0b 1 3 to to ADP bn999595x0b 1 4 hepatocytes hepatocyte NOUN bn999595x0b 1 5 ( ( PUNCT bn999595x0b 1 6 and and CCONJ bn999595x0b 1 7 other other ADJ bn999595x0b 1 8 types type NOUN bn999595x0b 1 9 of of ADP bn999595x0b 1 10 cells cell NOUN bn999595x0b 1 11 ) ) PUNCT bn999595x0b 1 12 maintained maintain VERB bn999595x0b 1 13 within within ADP bn999595x0b 1 14 the the DET bn999595x0b 1 15 extracapillary extracapillary ADJ bn999595x0b 1 16 space space NOUN bn999595x0b 1 17 of of ADP bn999595x0b 1 18 a a DET bn999595x0b 1 19 hollow hollow ADJ bn999595x0b 1 20 fiber fiber NOUN bn999595x0b 1 21 ( ( PUNCT bn999595x0b 1 22 hf hf NOUN bn999595x0b 1 23 ) ) PUNCT bn999595x0b 1 24 bioreactor bioreactor NOUN bn999595x0b 1 25 is be AUX bn999595x0b 1 26 believed believe VERB bn999595x0b 1 27 to to PART bn999595x0b 1 28 be be AUX bn999595x0b 1 29 transport transport NOUN bn999595x0b 1 30 limited limited ADJ bn999595x0b 1 31 because because SCONJ bn999595x0b 1 32 of of ADP bn999595x0b 1 33 the the DET bn999595x0b 1 34 low low ADJ bn999595x0b 1 35 solubility solubility NOUN bn999595x0b 1 36 of of ADP bn999595x0b 1 37 oxygen oxygen NOUN bn999595x0b 1 38 in in ADP bn999595x0b 1 39 aqueous aqueous ADJ bn999595x0b 1 40 media medium NOUN bn999595x0b 1 41 and and CCONJ bn999595x0b 1 42 the the DET bn999595x0b 1 43 high high ADJ bn999595x0b 1 44 cellular cellular ADJ bn999595x0b 1 45 oxygen oxygen NOUN bn999595x0b 1 46 demand demand NOUN bn999595x0b 1 47 . . PUNCT bn999595x0b 2 1 this this DET bn999595x0b 2 2 problem problem NOUN bn999595x0b 2 3 limits limit VERB bn999595x0b 2 4 hepatocyte hepatocyte NOUN bn999595x0b 2 5 functional functional ADJ bn999595x0b 2 6 capabilities capability NOUN bn999595x0b 2 7 . . PUNCT bn999595x0b 3 1 alleviating alleviate VERB bn999595x0b 3 2 this this DET bn999595x0b 3 3 problem problem NOUN bn999595x0b 3 4 is be AUX bn999595x0b 3 5 of of ADP bn999595x0b 3 6 significant significant ADJ bn999595x0b 3 7 biomedical biomedical ADJ bn999595x0b 3 8 interest interest NOUN bn999595x0b 3 9 , , PUNCT bn999595x0b 3 10 since since SCONJ bn999595x0b 3 11 hepatic hepatic ADJ bn999595x0b 3 12 hf hf NOUN bn999595x0b 3 13 bioreactors bioreactor NOUN bn999595x0b 3 14 can can AUX bn999595x0b 3 15 serve serve VERB bn999595x0b 3 16 as as ADP bn999595x0b 3 17 both both PRON bn999595x0b 3 18 an an DET bn999595x0b 3 19 in in ADP bn999595x0b 3 20 vitro vitro X bn999595x0b 3 21 model model NOUN bn999595x0b 3 22 for for ADP bn999595x0b 3 23 studying study VERB bn999595x0b 3 24 liver liver NOUN bn999595x0b 3 25 biotransformation biotransformation NOUN bn999595x0b 3 26 , , PUNCT bn999595x0b 3 27 detoxification detoxification NOUN bn999595x0b 3 28 , , PUNCT bn999595x0b 3 29 and and CCONJ bn999595x0b 3 30 metabolic metabolic NOUN bn999595x0b 3 31 functions function NOUN bn999595x0b 3 32 , , PUNCT bn999595x0b 3 33 and and CCONJ bn999595x0b 3 34 as as ADP bn999595x0b 3 35 a a DET bn999595x0b 3 36 device device NOUN bn999595x0b 3 37 used use VERB bn999595x0b 3 38 to to PART bn999595x0b 3 39 sustain sustain VERB bn999595x0b 3 40 patients patient NOUN bn999595x0b 3 41 suffering suffer VERB bn999595x0b 3 42 from from ADP bn999595x0b 3 43 acute acute ADJ bn999595x0b 3 44 liver liver NOUN bn999595x0b 3 45 failure failure NOUN bn999595x0b 3 46 . . PUNCT bn999595x0b 4 1 one one NUM bn999595x0b 4 2 means mean NOUN bn999595x0b 4 3 of of ADP bn999595x0b 4 4 improving improve VERB bn999595x0b 4 5 the the DET bn999595x0b 4 6 oxygen oxygen NOUN bn999595x0b 4 7 carrying carrying NOUN bn999595x0b 4 8 capacity capacity NOUN bn999595x0b 4 9 of of ADP bn999595x0b 4 10 a a DET bn999595x0b 4 11 hf hf NOUN bn999595x0b 4 12 bioreactor bioreactor NOUN bn999595x0b 4 13 media medium NOUN bn999595x0b 4 14 stream stream NOUN bn999595x0b 4 15 is be AUX bn999595x0b 4 16 via via ADP bn999595x0b 4 17 supplementation supplementation NOUN bn999595x0b 4 18 of of ADP bn999595x0b 4 19 the the DET bn999595x0b 4 20 circulating circulate VERB bn999595x0b 4 21 media medium NOUN bn999595x0b 4 22 stream stream NOUN bn999595x0b 4 23 with with ADP bn999595x0b 4 24 bovine bovine ADJ bn999595x0b 4 25 red red ADJ bn999595x0b 4 26 blood blood NOUN bn999595x0b 4 27 cells cell NOUN bn999595x0b 4 28 ( ( PUNCT bn999595x0b 4 29 brbcs brbc NOUN bn999595x0b 4 30 ) ) PUNCT bn999595x0b 4 31 . . PUNCT bn999595x0b 5 1 this this DET bn999595x0b 5 2 dissertation dissertation NOUN bn999595x0b 5 3 describes describe VERB bn999595x0b 5 4 the the DET bn999595x0b 5 5 initiation initiation NOUN bn999595x0b 5 6 and and CCONJ bn999595x0b 5 7 development development NOUN bn999595x0b 5 8 of of ADP bn999595x0b 5 9 a a DET bn999595x0b 5 10 project project NOUN bn999595x0b 5 11 aimed aim VERB bn999595x0b 5 12 at at ADP bn999595x0b 5 13 employing employ VERB bn999595x0b 5 14 brbc brbc PROPN bn999595x0b 5 15 supplementation supplementation NOUN bn999595x0b 5 16 to to PART bn999595x0b 5 17 improve improve VERB bn999595x0b 5 18 the the DET bn999595x0b 5 19 oxygen oxygen NOUN bn999595x0b 5 20 environment environment NOUN bn999595x0b 5 21 within within ADP bn999595x0b 5 22 the the DET bn999595x0b 5 23 hf hf NOUN bn999595x0b 5 24 bioreactor bioreactor NOUN bn999595x0b 5 25 hepatocyte hepatocyte NOUN bn999595x0b 5 26 space space NOUN bn999595x0b 5 27 . . PUNCT bn999595x0b 6 1 the the DET bn999595x0b 6 2 work work NOUN bn999595x0b 6 3 presented present VERB bn999595x0b 6 4 is be AUX bn999595x0b 6 5 organized organize VERB bn999595x0b 6 6 into into ADP bn999595x0b 6 7 three three NUM bn999595x0b 6 8 sections section NOUN bn999595x0b 6 9 . . PUNCT bn999595x0b 7 1 the the DET bn999595x0b 7 2 first first ADJ bn999595x0b 7 3 presents present VERB bn999595x0b 7 4 mathematical mathematical ADJ bn999595x0b 7 5 models model NOUN bn999595x0b 7 6 depicting depict VERB bn999595x0b 7 7 oxygen oxygen NOUN bn999595x0b 7 8 transport transport NOUN bn999595x0b 7 9 within within ADP bn999595x0b 7 10 the the DET bn999595x0b 7 11 bioreactor bioreactor NOUN bn999595x0b 7 12 system system NOUN bn999595x0b 7 13 . . PUNCT bn999595x0b 8 1 one one NUM bn999595x0b 8 2 of of ADP bn999595x0b 8 3 these these DET bn999595x0b 8 4 models model NOUN bn999595x0b 8 5 was be AUX bn999595x0b 8 6 also also ADV bn999595x0b 8 7 utilized utilize VERB bn999595x0b 8 8 to to PART bn999595x0b 8 9 demonstrate demonstrate VERB bn999595x0b 8 10 the the DET bn999595x0b 8 11 potential potential ADJ bn999595x0b 8 12 benefit benefit NOUN bn999595x0b 8 13 of of ADP bn999595x0b 8 14 brbc brbc PROPN bn999595x0b 8 15 supplementation supplementation NOUN bn999595x0b 8 16 . . PUNCT bn999595x0b 9 1 the the DET bn999595x0b 9 2 remaining remain VERB bn999595x0b 9 3 sections section NOUN bn999595x0b 9 4 present present VERB bn999595x0b 9 5 the the DET bn999595x0b 9 6 results result NOUN bn999595x0b 9 7 of of ADP bn999595x0b 9 8 experiments experiment NOUN bn999595x0b 9 9 aimed aim VERB bn999595x0b 9 10 at at ADP bn999595x0b 9 11 evaluating evaluate VERB bn999595x0b 9 12 brbc brbc NOUN bn999595x0b 9 13 supplementation supplementation NOUN bn999595x0b 9 14 within within ADP bn999595x0b 9 15 a a DET bn999595x0b 9 16 c3a c3a NOUN bn999595x0b 9 17 cell cell NOUN bn999595x0b 9 18 containing contain VERB bn999595x0b 9 19 hf hf NOUN bn999595x0b 9 20 bioreactor bioreactor NOUN bn999595x0b 9 21 and and CCONJ bn999595x0b 9 22 at at ADP bn999595x0b 9 23 examining examine VERB bn999595x0b 9 24 the the DET bn999595x0b 9 25 ability ability NOUN bn999595x0b 9 26 to to PART bn999595x0b 9 27 engineer engineer VERB bn999595x0b 9 28 brbc brbc PROPN bn999595x0b 9 29 properties property NOUN bn999595x0b 9 30 . . PUNCT bn999595x0b 10 1 briefly briefly ADV bn999595x0b 10 2 , , PUNCT bn999595x0b 10 3 it it PRON bn999595x0b 10 4 was be AUX bn999595x0b 10 5 found find VERB bn999595x0b 10 6 that that SCONJ bn999595x0b 10 7 a a DET bn999595x0b 10 8 c3a c3a NOUN bn999595x0b 10 9 cell cell NOUN bn999595x0b 10 10 containing contain VERB bn999595x0b 10 11 hf hf NOUN bn999595x0b 10 12 bioreactor bioreactor NOUN bn999595x0b 10 13 maintained maintain VERB bn999595x0b 10 14 with with SCONJ bn999595x0b 10 15 media medium NOUN bn999595x0b 10 16 brbc brbc PROPN bn999595x0b 10 17 supplementation supplementation NOUN bn999595x0b 10 18 exhibited exhibit VERB bn999595x0b 10 19 signs sign NOUN bn999595x0b 10 20 of of ADP bn999595x0b 10 21 an an DET bn999595x0b 10 22 improved improved ADJ bn999595x0b 10 23 c3a c3a NOUN bn999595x0b 10 24 cell cell NOUN bn999595x0b 10 25 space space NOUN bn999595x0b 10 26 oxygen oxygen NOUN bn999595x0b 10 27 environment environment NOUN bn999595x0b 10 28 in in ADP bn999595x0b 10 29 comparison comparison NOUN bn999595x0b 10 30 to to ADP bn999595x0b 10 31 a a DET bn999595x0b 10 32 control control NOUN bn999595x0b 10 33 ( ( PUNCT bn999595x0b 10 34 a a DET bn999595x0b 10 35 c3a c3a NOUN bn999595x0b 10 36 cell cell NOUN bn999595x0b 10 37 containing contain VERB bn999595x0b 10 38 hf hf NOUN bn999595x0b 10 39 bioreactor bioreactor NOUN bn999595x0b 10 40 not not PART bn999595x0b 10 41 maintained maintain VERB bn999595x0b 10 42 with with ADP bn999595x0b 10 43 brbc brbc PROPN bn999595x0b 10 44 supplementation supplementation NOUN bn999595x0b 10 45 ) ) PUNCT bn999595x0b 10 46 . . PUNCT bn999595x0b 11 1 additionally additionally ADV bn999595x0b 11 2 , , PUNCT bn999595x0b 11 3 from from ADP bn999595x0b 11 4 the the DET bn999595x0b 11 5 research research NOUN bn999595x0b 11 6 conducted conduct VERB bn999595x0b 11 7 on on ADP bn999595x0b 11 8 engineering engineer VERB bn999595x0b 11 9 the the DET bn999595x0b 11 10 properties property NOUN bn999595x0b 11 11 of of ADP bn999595x0b 11 12 brbcs brbc NOUN bn999595x0b 11 13 , , PUNCT bn999595x0b 11 14 the the DET bn999595x0b 11 15 ability ability NOUN bn999595x0b 11 16 to to PART bn999595x0b 11 17 improve improve VERB bn999595x0b 11 18 the the DET bn999595x0b 11 19 cell cell NOUN bn999595x0b 11 20 's 's PART bn999595x0b 11 21 osmotic osmotic ADJ bn999595x0b 11 22 stability stability NOUN bn999595x0b 11 23 and and CCONJ bn999595x0b 11 24 to to PART bn999595x0b 11 25 alter alter VERB bn999595x0b 11 26 its its PRON bn999595x0b 11 27 oxygen oxygen NOUN bn999595x0b 11 28 binding bind VERB bn999595x0b 11 29 / / SYM bn999595x0b 11 30 dissociation dissociation NOUN bn999595x0b 11 31 properties property NOUN bn999595x0b 11 32 was be AUX bn999595x0b 11 33 demonstrated demonstrate VERB bn999595x0b 11 34 . . PUNCT bn999595x0b 12 1 this this PRON bn999595x0b 12 2 could could AUX bn999595x0b 12 3 allow allow VERB bn999595x0b 12 4 for for ADP bn999595x0b 12 5 the the DET bn999595x0b 12 6 creation creation NOUN bn999595x0b 12 7 of of ADP bn999595x0b 12 8 a a DET bn999595x0b 12 9 tunable tunable ADJ bn999595x0b 12 10 , , PUNCT bn999595x0b 12 11 novel novel ADJ bn999595x0b 12 12 oxygen oxygen NOUN bn999595x0b 12 13 carrier carrier NOUN bn999595x0b 12 14 well well ADV bn999595x0b 12 15 - - PUNCT bn999595x0b 12 16 suited suit VERB bn999595x0b 12 17 for for ADP bn999595x0b 12 18 use use NOUN bn999595x0b 12 19 within within ADP bn999595x0b 12 20 a a DET bn999595x0b 12 21 hf hf NOUN bn999595x0b 12 22 bioreactor bioreactor NOUN bn999595x0b 12 23 system system NOUN bn999595x0b 12 24 . . PUNCT bn999595x0b 13 1 lastly lastly ADV bn999595x0b 13 2 , , PUNCT bn999595x0b 13 3 the the DET bn999595x0b 13 4 results result NOUN bn999595x0b 13 5 obtained obtain VERB bn999595x0b 13 6 from from ADP bn999595x0b 13 7 this this DET bn999595x0b 13 8 work work NOUN bn999595x0b 13 9 have have AUX bn999595x0b 13 10 led lead VERB bn999595x0b 13 11 to to ADP bn999595x0b 13 12 the the DET bn999595x0b 13 13 design design NOUN bn999595x0b 13 14 of of ADP bn999595x0b 13 15 a a DET bn999595x0b 13 16 rigorous rigorous ADJ bn999595x0b 13 17 set set NOUN bn999595x0b 13 18 of of ADP bn999595x0b 13 19 experiments experiment NOUN bn999595x0b 13 20 which which PRON bn999595x0b 13 21 utilize utilize VERB bn999595x0b 13 22 brbc brbc NOUN bn999595x0b 13 23 supplementation supplementation NOUN bn999595x0b 13 24 to to PART bn999595x0b 13 25 explore explore VERB bn999595x0b 13 26 the the DET bn999595x0b 13 27 impact impact NOUN bn999595x0b 13 28 ( ( PUNCT bn999595x0b 13 29 on on ADP bn999595x0b 13 30 function function NOUN bn999595x0b 13 31 , , PUNCT bn999595x0b 13 32 etc etc X bn999595x0b 13 33 ) ) PUNCT bn999595x0b 13 34 of of ADP bn999595x0b 13 35 oxygen oxygen NOUN bn999595x0b 13 36 provision provision NOUN bn999595x0b 13 37 on on ADP bn999595x0b 13 38 hepatocytes hepatocyte NOUN bn999595x0b 13 39 maintained maintain VERB bn999595x0b 13 40 within within ADP bn999595x0b 13 41 a a DET bn999595x0b 13 42 hf hf NOUN bn999595x0b 13 43 bioreactor bioreactor NOUN bn999595x0b 13 44 . . PUNCT