id sid tid token lemma pos bg257d29b92 1 1 microtubules microtubule NOUN bg257d29b92 1 2 are be AUX bg257d29b92 1 3 essential essential ADJ bg257d29b92 1 4 to to ADP bg257d29b92 1 5 cellular cellular ADJ bg257d29b92 1 6 organization organization NOUN bg257d29b92 1 7 and and CCONJ bg257d29b92 1 8 are be AUX bg257d29b92 1 9 thus thus ADV bg257d29b92 1 10 regulated regulate VERB bg257d29b92 1 11 by by ADP bg257d29b92 1 12 many many ADJ bg257d29b92 1 13 proteins protein NOUN bg257d29b92 1 14 . . PUNCT bg257d29b92 2 1 one one NUM bg257d29b92 2 2 family family NOUN bg257d29b92 2 3 of of ADP bg257d29b92 2 4 these these DET bg257d29b92 2 5 regulatory regulatory ADJ bg257d29b92 2 6 proteins protein NOUN bg257d29b92 2 7 is be AUX bg257d29b92 2 8 known know VERB bg257d29b92 2 9 as as ADP bg257d29b92 2 10 the the DET bg257d29b92 2 11 clipr clipr X bg257d29b92 2 12 ( ( PUNCT bg257d29b92 2 13 clip-170 clip-170 X bg257d29b92 2 14 related relate VERB bg257d29b92 2 15 ) ) PUNCT bg257d29b92 2 16 family family NOUN bg257d29b92 2 17 , , PUNCT bg257d29b92 2 18 so so ADV bg257d29b92 2 19 - - PUNCT bg257d29b92 2 20 called call VERB bg257d29b92 2 21 because because SCONJ bg257d29b92 2 22 its its PRON bg257d29b92 2 23 members member NOUN bg257d29b92 2 24 contain contain VERB bg257d29b92 2 25 conserved conserve VERB bg257d29b92 2 26 cap cap NOUN bg257d29b92 2 27 - - PUNCT bg257d29b92 2 28 gly gly NOUN bg257d29b92 2 29 domains domain NOUN bg257d29b92 2 30 originally originally ADV bg257d29b92 2 31 found find VERB bg257d29b92 2 32 in in ADP bg257d29b92 2 33 clip-170 clip-170 SPACE bg257d29b92 2 34 . . PUNCT bg257d29b92 3 1 this this DET bg257d29b92 3 2 thesis thesis NOUN bg257d29b92 3 3 describes describe VERB bg257d29b92 3 4 the the DET bg257d29b92 3 5 characterization characterization NOUN bg257d29b92 3 6 of of ADP bg257d29b92 3 7 an an DET bg257d29b92 3 8 alternatively alternatively ADV bg257d29b92 3 9 spliced spliced ADJ bg257d29b92 3 10 member member NOUN bg257d29b92 3 11 of of ADP bg257d29b92 3 12 this this DET bg257d29b92 3 13 family family NOUN bg257d29b92 3 14 , , PUNCT bg257d29b92 3 15 clipr76 clipr76 SPACE bg257d29b92 3 16 , , PUNCT bg257d29b92 3 17 by by ADP bg257d29b92 3 18 a a DET bg257d29b92 3 19 combination combination NOUN bg257d29b92 3 20 of of ADP bg257d29b92 3 21 cell cell NOUN bg257d29b92 3 22 biological biological ADJ bg257d29b92 3 23 , , PUNCT bg257d29b92 3 24 biochemical biochemical ADJ bg257d29b92 3 25 , , PUNCT bg257d29b92 3 26 and and CCONJ bg257d29b92 3 27 bioinformatic bioinformatic ADJ bg257d29b92 3 28 approaches approach NOUN bg257d29b92 3 29 . . PUNCT bg257d29b92 4 1 clipr76 clipr76 SPACE bg257d29b92 4 2 - - PROPN bg257d29b92 4 3 4 4 NUM bg257d29b92 4 4 , , PUNCT bg257d29b92 4 5 the the DET bg257d29b92 4 6 smallest small ADJ bg257d29b92 4 7 human human ADJ bg257d29b92 4 8 splice splice NOUN bg257d29b92 4 9 isoform isoform NOUN bg257d29b92 4 10 , , PUNCT bg257d29b92 4 11 contains contain VERB bg257d29b92 4 12 a a DET bg257d29b92 4 13 hydrophobic hydrophobic NOUN bg257d29b92 4 14 c c NOUN bg257d29b92 4 15 - - NOUN bg257d29b92 4 16 terminus terminus NOUN bg257d29b92 4 17 that that PRON bg257d29b92 4 18 drives drive VERB bg257d29b92 4 19 er er INTJ bg257d29b92 4 20 localization localization NOUN bg257d29b92 4 21 and and CCONJ bg257d29b92 4 22 aligns align VERB bg257d29b92 4 23 with with ADP bg257d29b92 4 24 the the DET bg257d29b92 4 25 c c NOUN bg257d29b92 4 26 - - PUNCT bg257d29b92 4 27 terminal terminal NOUN bg257d29b92 4 28 golgi golgi NOUN bg257d29b92 4 29 - - PUNCT bg257d29b92 4 30 localizing localize VERB bg257d29b92 4 31 domain domain NOUN bg257d29b92 4 32 of of ADP bg257d29b92 4 33 the the DET bg257d29b92 4 34 clipr76 clipr76 ADJ bg257d29b92 4 35 relative relative NOUN bg257d29b92 4 36 clipr-59 clipr-59 ADV bg257d29b92 4 37 . . PUNCT bg257d29b92 5 1 the the DET bg257d29b92 5 2 mechanism mechanism NOUN bg257d29b92 5 3 of of ADP bg257d29b92 5 4 clipr76 clipr76 SPACE bg257d29b92 5 5 - - PUNCT bg257d29b92 5 6 4 4 NUM bg257d29b92 5 7 membrane membrane NOUN bg257d29b92 5 8 localization localization NOUN bg257d29b92 5 9 was be AUX bg257d29b92 5 10 investigated investigate VERB bg257d29b92 5 11 by by ADP bg257d29b92 5 12 mutating mutate VERB bg257d29b92 5 13 a a DET bg257d29b92 5 14 key key ADJ bg257d29b92 5 15 conserved conserve VERB bg257d29b92 5 16 cysteine cysteine NOUN bg257d29b92 5 17 necessary necessary ADJ bg257d29b92 5 18 for for ADP bg257d29b92 5 19 clipr-59 clipr-59 NOUN bg257d29b92 5 20 localization localization NOUN bg257d29b92 5 21 . . PUNCT bg257d29b92 6 1 cells cell NOUN bg257d29b92 6 2 transfected transfecte VERB bg257d29b92 6 3 with with ADP bg257d29b92 6 4 gfp gfp ADJ bg257d29b92 6 5 - - PUNCT bg257d29b92 6 6 fusion fusion NOUN bg257d29b92 6 7 mutant mutant NOUN bg257d29b92 6 8 clipr76 clipr76 SPACE bg257d29b92 6 9 - - PUNCT bg257d29b92 6 10 4 4 NUM bg257d29b92 6 11 were be AUX bg257d29b92 6 12 visualized visualize VERB bg257d29b92 6 13 by by ADP bg257d29b92 6 14 immunofluorescence immunofluorescence NOUN bg257d29b92 6 15 microscopy microscopy NOUN bg257d29b92 6 16 displayed display VERB bg257d29b92 6 17 unperturbed unperturbed ADJ bg257d29b92 6 18 er er INTJ bg257d29b92 6 19 localization localization NOUN bg257d29b92 6 20 . . PUNCT bg257d29b92 7 1 this this PRON bg257d29b92 7 2 indicates indicate VERB bg257d29b92 7 3 that that SCONJ bg257d29b92 7 4 clipr76 clipr76 SPACE bg257d29b92 7 5 - - PUNCT bg257d29b92 7 6 4 4 NUM bg257d29b92 7 7 and and CCONJ bg257d29b92 7 8 clipr-59 clipr-59 AUX bg257d29b92 7 9 target target VERB bg257d29b92 7 10 their their PRON bg257d29b92 7 11 membranes membrane NOUN bg257d29b92 7 12 via via ADP bg257d29b92 7 13 distinct distinct ADJ bg257d29b92 7 14 mechanisms mechanism NOUN bg257d29b92 7 15 . . PUNCT bg257d29b92 8 1 the the DET bg257d29b92 8 2 nature nature NOUN bg257d29b92 8 3 of of ADP bg257d29b92 8 4 the the DET bg257d29b92 8 5 clipr76 clipr76 SPACE bg257d29b92 8 6 - - PUNCT bg257d29b92 8 7 microtubule microtubule ADJ bg257d29b92 8 8 interaction interaction NOUN bg257d29b92 8 9 was be AUX bg257d29b92 8 10 then then ADV bg257d29b92 8 11 investigated investigate VERB bg257d29b92 8 12 . . PUNCT bg257d29b92 9 1 microtubule microtubule NOUN bg257d29b92 9 2 cosedimentation cosedimentation NOUN bg257d29b92 9 3 assays assay VERB bg257d29b92 9 4 with with ADP bg257d29b92 9 5 purified purify VERB bg257d29b92 9 6 proteins protein NOUN bg257d29b92 9 7 showed show VERB bg257d29b92 9 8 that that SCONJ bg257d29b92 9 9 two two NUM bg257d29b92 9 10 of of ADP bg257d29b92 9 11 the the DET bg257d29b92 9 12 clipr76 clipr76 ADJ bg257d29b92 9 13 cap cap NOUN bg257d29b92 9 14 - - PUNCT bg257d29b92 9 15 glys gly NOUN bg257d29b92 9 16 , , PUNCT bg257d29b92 9 17 including include VERB bg257d29b92 9 18 one one NUM bg257d29b92 9 19 common common ADJ bg257d29b92 9 20 to to ADP bg257d29b92 9 21 all all DET bg257d29b92 9 22 isoforms isoform NOUN bg257d29b92 9 23 , , PUNCT bg257d29b92 9 24 bind bind VERB bg257d29b92 9 25 mts mts NOUN bg257d29b92 9 26 with with ADP bg257d29b92 9 27 affinities affinity NOUN bg257d29b92 9 28 in in ADP bg257d29b92 9 29 the the DET bg257d29b92 9 30 1åµm 1åµm NUM bg257d29b92 9 31 range range NOUN bg257d29b92 9 32 and and CCONJ bg257d29b92 9 33 also also ADV bg257d29b92 9 34 promote promote VERB bg257d29b92 9 35 mt mt PROPN bg257d29b92 9 36 polymerization polymerization NOUN bg257d29b92 9 37 . . PUNCT bg257d29b92 10 1 these these DET bg257d29b92 10 2 observations observation NOUN bg257d29b92 10 3 demonstrate demonstrate VERB bg257d29b92 10 4 that that SCONJ bg257d29b92 10 5 clipr-76 clipr-76 PROPN bg257d29b92 10 6 proteins protein NOUN bg257d29b92 10 7 act act VERB bg257d29b92 10 8 on on ADP bg257d29b92 10 9 mts mts NOUN bg257d29b92 10 10 directly directly ADV bg257d29b92 10 11 and and CCONJ bg257d29b92 10 12 do do VERB bg257d29b92 10 13 so so ADV bg257d29b92 10 14 through through ADP bg257d29b92 10 15 their their PRON bg257d29b92 10 16 conserved conserved ADJ bg257d29b92 10 17 cap cap NOUN bg257d29b92 10 18 - - PUNCT bg257d29b92 10 19 gly gly NOUN bg257d29b92 10 20 domains domain NOUN bg257d29b92 10 21 . . PUNCT bg257d29b92 11 1 while while SCONJ bg257d29b92 11 2 the the DET bg257d29b92 11 3 mt mt PROPN bg257d29b92 11 4 - - PUNCT bg257d29b92 11 5 binding bind VERB bg257d29b92 11 6 ability ability NOUN bg257d29b92 11 7 of of ADP bg257d29b92 11 8 the the DET bg257d29b92 11 9 clipr76 clipr76 ADJ bg257d29b92 11 10 cap cap NOUN bg257d29b92 11 11 - - PUNCT bg257d29b92 11 12 gly gly NOUN bg257d29b92 11 13 domains domain NOUN bg257d29b92 11 14 is be AUX bg257d29b92 11 15 similar similar ADJ bg257d29b92 11 16 to to ADP bg257d29b92 11 17 that that PRON bg257d29b92 11 18 of of ADP bg257d29b92 11 19 the the DET bg257d29b92 11 20 clip-170 clip-170 X bg257d29b92 11 21 cap cap NOUN bg257d29b92 11 22 - - PUNCT bg257d29b92 11 23 gly gly NOUN bg257d29b92 11 24 domains domain NOUN bg257d29b92 11 25 , , PUNCT bg257d29b92 11 26 cosedimentation cosedimentation NOUN bg257d29b92 11 27 assays assay VERB bg257d29b92 11 28 in in ADP bg257d29b92 11 29 the the DET bg257d29b92 11 30 presence presence NOUN bg257d29b92 11 31 of of ADP bg257d29b92 11 32 eb1 eb1 PRON bg257d29b92 11 33 showed show VERB bg257d29b92 11 34 that that SCONJ bg257d29b92 11 35 clipr76 clipr76 PROPN bg257d29b92 11 36 lacks lack VERB bg257d29b92 11 37 that that DET bg257d29b92 11 38 ability ability NOUN bg257d29b92 11 39 to to PART bg257d29b92 11 40 bind bind VERB bg257d29b92 11 41 eb1 eb1 PROPN bg257d29b92 11 42 . . PUNCT bg257d29b92 11 43 bioinformatics bioinformatic NOUN bg257d29b92 11 44 was be AUX bg257d29b92 11 45 then then ADV bg257d29b92 11 46 used use VERB bg257d29b92 11 47 to to PART bg257d29b92 11 48 identify identify VERB bg257d29b92 11 49 aspects aspect NOUN bg257d29b92 11 50 of of ADP bg257d29b92 11 51 the the DET bg257d29b92 11 52 cap cap NOUN bg257d29b92 11 53 - - PUNCT bg257d29b92 11 54 gly gly NOUN bg257d29b92 11 55 structures structure NOUN bg257d29b92 11 56 that that PRON bg257d29b92 11 57 could could AUX bg257d29b92 11 58 mediate mediate VERB bg257d29b92 11 59 these these DET bg257d29b92 11 60 different different ADJ bg257d29b92 11 61 activities activity NOUN bg257d29b92 11 62 . . PUNCT bg257d29b92 12 1 multiple multiple ADJ bg257d29b92 12 2 sequence sequence NOUN bg257d29b92 12 3 alignments alignment NOUN bg257d29b92 12 4 of of ADP bg257d29b92 12 5 several several ADJ bg257d29b92 12 6 cap cap NOUN bg257d29b92 12 7 - - PUNCT bg257d29b92 12 8 gly gly NOUN bg257d29b92 12 9 domains domain NOUN bg257d29b92 12 10 were be AUX bg257d29b92 12 11 generated generate VERB bg257d29b92 12 12 and and CCONJ bg257d29b92 12 13 then then ADV bg257d29b92 12 14 mapped map VERB bg257d29b92 12 15 onto onto ADP bg257d29b92 12 16 their their PRON bg257d29b92 12 17 corresponding correspond VERB bg257d29b92 12 18 3d 3d NOUN bg257d29b92 12 19 structures structure NOUN bg257d29b92 12 20 . . PUNCT bg257d29b92 13 1 there there PRON bg257d29b92 13 2 is be VERB bg257d29b92 13 3 a a DET bg257d29b92 13 4 large large ADJ bg257d29b92 13 5 conserved conserved ADJ bg257d29b92 13 6 patch patch NOUN bg257d29b92 13 7 on on ADP bg257d29b92 13 8 all all PRON bg257d29b92 13 9 of of ADP bg257d29b92 13 10 the the DET bg257d29b92 13 11 clipr76 clipr76 ADJ bg257d29b92 13 12 cap cap NOUN bg257d29b92 13 13 - - PUNCT bg257d29b92 13 14 gly gly NOUN bg257d29b92 13 15 domains domain NOUN bg257d29b92 13 16 , , PUNCT bg257d29b92 13 17 corresponding correspond VERB bg257d29b92 13 18 to to ADP bg257d29b92 13 19 residues residue NOUN bg257d29b92 13 20 that that PRON bg257d29b92 13 21 may may AUX bg257d29b92 13 22 mediate mediate VERB bg257d29b92 13 23 mt mt PROPN bg257d29b92 13 24 - - PUNCT bg257d29b92 13 25 cap cap NOUN bg257d29b92 13 26 - - PUNCT bg257d29b92 13 27 gly gly NOUN bg257d29b92 13 28 interactions interaction NOUN bg257d29b92 13 29 . . PUNCT bg257d29b92 14 1 a a DET bg257d29b92 14 2 comparison comparison NOUN bg257d29b92 14 3 of of ADP bg257d29b92 14 4 the the DET bg257d29b92 14 5 two two NUM bg257d29b92 14 6 cap cap NOUN bg257d29b92 14 7 - - PUNCT bg257d29b92 14 8 gly gly NOUN bg257d29b92 14 9 domains domain NOUN bg257d29b92 14 10 of of ADP bg257d29b92 14 11 clip-170 clip-170 PRON bg257d29b92 14 12 revealed reveal VERB bg257d29b92 14 13 a a DET bg257d29b92 14 14 region region NOUN bg257d29b92 14 15 of of ADP bg257d29b92 14 16 non non NOUN bg257d29b92 14 17 - - NOUN bg257d29b92 14 18 conservation conservation NOUN bg257d29b92 14 19 which which PRON bg257d29b92 14 20 could could AUX bg257d29b92 14 21 explain explain VERB bg257d29b92 14 22 the the DET bg257d29b92 14 23 two two NUM bg257d29b92 14 24 cap cap NOUN bg257d29b92 14 25 - - PUNCT bg257d29b92 14 26 glys gly NOUN bg257d29b92 14 27 ' ' PART bg257d29b92 14 28 different different ADJ bg257d29b92 14 29 affinities affinity NOUN bg257d29b92 14 30 for for ADP bg257d29b92 14 31 eb1 eb1 SPACE bg257d29b92 14 32 . . X bg257d29b92 15 1 these these DET bg257d29b92 15 2 regions region NOUN bg257d29b92 15 3 of of ADP bg257d29b92 15 4 non non ADJ bg257d29b92 15 5 - - ADJ bg257d29b92 15 6 conservation conservation NOUN bg257d29b92 15 7 remain remain VERB bg257d29b92 15 8 important important ADJ bg257d29b92 15 9 targets target NOUN bg257d29b92 15 10 for for ADP bg257d29b92 15 11 future future ADJ bg257d29b92 15 12 mutagenesis mutagenesis NOUN bg257d29b92 15 13 studies study NOUN bg257d29b92 15 14 . . PUNCT bg257d29b92 16 1 finally finally ADV bg257d29b92 16 2 , , PUNCT bg257d29b92 16 3 using use VERB bg257d29b92 16 4 a a DET bg257d29b92 16 5 k-12 k-12 PROPN bg257d29b92 16 6 outreach outreach NOUN bg257d29b92 16 7 opportunity opportunity NOUN bg257d29b92 16 8 , , PUNCT bg257d29b92 16 9 a a DET bg257d29b92 16 10 brief brief ADJ bg257d29b92 16 11 survey survey NOUN bg257d29b92 16 12 was be AUX bg257d29b92 16 13 developed develop VERB bg257d29b92 16 14 to to PART bg257d29b92 16 15 rate rate VERB bg257d29b92 16 16 students student NOUN bg257d29b92 16 17 ' ' PART bg257d29b92 16 18 attitudes attitude NOUN bg257d29b92 16 19 towards towards ADP bg257d29b92 16 20 science science NOUN bg257d29b92 16 21 and and CCONJ bg257d29b92 16 22 showed show VERB bg257d29b92 16 23 that that SCONJ bg257d29b92 16 24 interactions interaction NOUN bg257d29b92 16 25 with with ADP bg257d29b92 16 26 scientists scientist NOUN bg257d29b92 16 27 and and CCONJ bg257d29b92 16 28 inquiry inquiry NOUN bg257d29b92 16 29 based base VERB bg257d29b92 16 30 projects project NOUN bg257d29b92 16 31 significantly significantly ADV bg257d29b92 16 32 improved improve VERB bg257d29b92 16 33 student student NOUN bg257d29b92 16 34 attitudes attitude NOUN bg257d29b92 16 35 towards towards ADP bg257d29b92 16 36 science science NOUN bg257d29b92 16 37 . . PUNCT