id sid tid token lemma pos b8515m62t1x 1 1 the the DET b8515m62t1x 1 2 research research NOUN b8515m62t1x 1 3 in in ADP b8515m62t1x 1 4 this this DET b8515m62t1x 1 5 dissertation dissertation NOUN b8515m62t1x 1 6 focuses focus VERB b8515m62t1x 1 7 on on ADP b8515m62t1x 1 8 the the DET b8515m62t1x 1 9 synthesis synthesis NOUN b8515m62t1x 1 10 and and CCONJ b8515m62t1x 1 11 in in ADP b8515m62t1x 1 12 vitro vitro X b8515m62t1x 1 13 testing testing NOUN b8515m62t1x 1 14 of of ADP b8515m62t1x 1 15 structurally structurally ADV b8515m62t1x 1 16 novel novel ADJ b8515m62t1x 1 17 antibacterial antibacterial ADJ b8515m62t1x 1 18 agents agent NOUN b8515m62t1x 1 19 derived derive VERB b8515m62t1x 1 20 from from ADP b8515m62t1x 1 21 acylnitroso acylnitroso PROPN b8515m62t1x 1 22 diels diel NOUN b8515m62t1x 1 23 alder alder NOUN b8515m62t1x 1 24 adducts adduct NOUN b8515m62t1x 1 25 . . PUNCT b8515m62t1x 2 1 the the DET b8515m62t1x 2 2 striking striking ADJ b8515m62t1x 2 3 structural structural ADJ b8515m62t1x 2 4 similarity similarity NOUN b8515m62t1x 2 5 of of ADP b8515m62t1x 2 6 ? ? PUNCT b8515m62t1x 2 7 -lactam -lactam VERB b8515m62t1x 2 8 antibacterial antibacterial ADJ b8515m62t1x 2 9 agents agent NOUN b8515m62t1x 2 10 to to ADP b8515m62t1x 2 11 isoxazolidines isoxazolidine NOUN b8515m62t1x 2 12 derived derive VERB b8515m62t1x 2 13 from from ADP b8515m62t1x 2 14 acylnitroso acylnitroso PROPN b8515m62t1x 2 15 diels diel NOUN b8515m62t1x 2 16 alder alder NOUN b8515m62t1x 2 17 adducts adduct NOUN b8515m62t1x 2 18 led lead VERB b8515m62t1x 2 19 to to ADP b8515m62t1x 2 20 the the DET b8515m62t1x 2 21 hypothesis hypothesis NOUN b8515m62t1x 2 22 that that SCONJ b8515m62t1x 2 23 appropriately appropriately ADV b8515m62t1x 2 24 elaborated elaborate VERB b8515m62t1x 2 25 isoxazolidines isoxazolidine NOUN b8515m62t1x 2 26 might might AUX b8515m62t1x 2 27 act act VERB b8515m62t1x 2 28 as as ADP b8515m62t1x 2 29 a a DET b8515m62t1x 2 30 ? ? PROPN b8515m62t1x 2 31 -lactam -lactam ADJ b8515m62t1x 2 32 surrogate surrogate NOUN b8515m62t1x 2 33 . . PUNCT b8515m62t1x 3 1 in in ADP b8515m62t1x 3 2 order order NOUN b8515m62t1x 3 3 to to PART b8515m62t1x 3 4 test test VERB b8515m62t1x 3 5 this this DET b8515m62t1x 3 6 hypothesis hypothesis NOUN b8515m62t1x 3 7 , , PUNCT b8515m62t1x 3 8 several several ADJ b8515m62t1x 3 9 isoxazolidines isoxazolidine NOUN b8515m62t1x 3 10 were be AUX b8515m62t1x 3 11 synthesized synthesize VERB b8515m62t1x 3 12 and and CCONJ b8515m62t1x 3 13 tested test VERB b8515m62t1x 3 14 against against ADP b8515m62t1x 3 15 e. e. PROPN b8515m62t1x 3 16 coli coli PROPN b8515m62t1x 3 17 x-580 x-580 SPACE b8515m62t1x 3 18 , , PUNCT b8515m62t1x 3 19 which which PRON b8515m62t1x 3 20 is be AUX b8515m62t1x 3 21 a a DET b8515m62t1x 3 22 stain stain NOUN b8515m62t1x 3 23 of of ADP b8515m62t1x 3 24 e. e. PROPN b8515m62t1x 3 25 coli coli PROPN b8515m62t1x 3 26 that that PRON b8515m62t1x 3 27 is be AUX b8515m62t1x 3 28 hypersensitive hypersensitive ADJ b8515m62t1x 3 29 to to ADP b8515m62t1x 3 30 ? ? PUNCT b8515m62t1x 3 31 -lactam -lactam VERB b8515m62t1x 3 32 antibacterial antibacterial ADJ b8515m62t1x 3 33 agents agent NOUN b8515m62t1x 3 34 , , PUNCT b8515m62t1x 3 35 and and CCONJ b8515m62t1x 3 36 were be AUX b8515m62t1x 3 37 found find VERB b8515m62t1x 3 38 to to PART b8515m62t1x 3 39 have have VERB b8515m62t1x 3 40 activity activity NOUN b8515m62t1x 3 41 . . PUNCT b8515m62t1x 4 1 in in ADP b8515m62t1x 4 2 order order NOUN b8515m62t1x 4 3 to to PART b8515m62t1x 4 4 increase increase VERB b8515m62t1x 4 5 the the DET b8515m62t1x 4 6 potency potency ADJ b8515m62t1x 4 7 and and CCONJ b8515m62t1x 4 8 broad broad ADJ b8515m62t1x 4 9 spectrum spectrum NOUN b8515m62t1x 4 10 antibacterial antibacterial ADJ b8515m62t1x 4 11 activity activity NOUN b8515m62t1x 4 12 , , PUNCT b8515m62t1x 4 13 additional additional ADJ b8515m62t1x 4 14 isoxazolidines isoxazolidine NOUN b8515m62t1x 4 15 were be AUX b8515m62t1x 4 16 synthesized synthesize VERB b8515m62t1x 4 17 which which PRON b8515m62t1x 4 18 incorporate incorporate VERB b8515m62t1x 4 19 side side NOUN b8515m62t1x 4 20 chains chain NOUN b8515m62t1x 4 21 which which PRON b8515m62t1x 4 22 are be AUX b8515m62t1x 4 23 analogous analogous ADJ b8515m62t1x 4 24 to to ADP b8515m62t1x 4 25 physiologically physiologically ADV b8515m62t1x 4 26 relevant relevant ADJ b8515m62t1x 4 27 side side NOUN b8515m62t1x 4 28 chains chain NOUN b8515m62t1x 4 29 that that PRON b8515m62t1x 4 30 many many ADJ b8515m62t1x 4 31 effective effective ADJ b8515m62t1x 4 32 ? ? PUNCT b8515m62t1x 5 1 -lactam -lactam ADJ b8515m62t1x 5 2 antibiotics antibiotic NOUN b8515m62t1x 5 3 have have VERB b8515m62t1x 5 4 . . PUNCT b8515m62t1x 6 1 these these DET b8515m62t1x 6 2 side side NOUN b8515m62t1x 6 3 chains chain NOUN b8515m62t1x 6 4 included include VERB b8515m62t1x 6 5 phenylglycine phenylglycine NOUN b8515m62t1x 6 6 and and CCONJ b8515m62t1x 6 7 amino amino NOUN b8515m62t1x 6 8 thiazol thiazol NOUN b8515m62t1x 6 9 methoxy methoxy NOUN b8515m62t1x 6 10 oxime oxime PROPN b8515m62t1x 6 11 ( ( PUNCT b8515m62t1x 6 12 atmo atmo PROPN b8515m62t1x 6 13 ) ) PUNCT b8515m62t1x 6 14 . . PUNCT b8515m62t1x 7 1 the the DET b8515m62t1x 7 2 current current ADJ b8515m62t1x 7 3 progress progress NOUN b8515m62t1x 7 4 towards towards ADP b8515m62t1x 7 5 a a DET b8515m62t1x 7 6 diketopiperzine diketopiperzine NOUN b8515m62t1x 7 7 derived derive VERB b8515m62t1x 7 8 from from ADP b8515m62t1x 7 9 an an DET b8515m62t1x 7 10 isoxazolidine isoxazolidine NOUN b8515m62t1x 7 11 is be AUX b8515m62t1x 7 12 presented present VERB b8515m62t1x 7 13 which which PRON b8515m62t1x 7 14 could could AUX b8515m62t1x 7 15 also also ADV b8515m62t1x 7 16 exhibit exhibit VERB b8515m62t1x 7 17 antibacterial antibacterial ADJ b8515m62t1x 7 18 activity activity NOUN b8515m62t1x 7 19 . . PUNCT b8515m62t1x 8 1 the the DET b8515m62t1x 8 2 efforts effort NOUN b8515m62t1x 8 3 towards towards ADP b8515m62t1x 8 4 an an DET b8515m62t1x 8 5 isoxazolidine isoxazolidine NOUN b8515m62t1x 8 6 containing contain VERB b8515m62t1x 8 7 an an DET b8515m62t1x 8 8 alcohol alcohol NOUN b8515m62t1x 8 9 in in ADP b8515m62t1x 8 10 the the DET b8515m62t1x 8 11 side side NOUN b8515m62t1x 8 12 chain chain NOUN b8515m62t1x 8 13 are be AUX b8515m62t1x 8 14 shown show VERB b8515m62t1x 8 15 and and CCONJ b8515m62t1x 8 16 the the DET b8515m62t1x 8 17 attachment attachment NOUN b8515m62t1x 8 18 of of ADP b8515m62t1x 8 19 it it PRON b8515m62t1x 8 20 to to PART b8515m62t1x 8 21 deferoxamine deferoxamine VERB b8515m62t1x 8 22 ( ( PUNCT b8515m62t1x 8 23 dfo dfo PROPN b8515m62t1x 8 24 ) ) PUNCT b8515m62t1x 8 25 which which PRON b8515m62t1x 8 26 is be AUX b8515m62t1x 8 27 a a DET b8515m62t1x 8 28 siderophore siderophore NOUN b8515m62t1x 8 29 is be AUX b8515m62t1x 8 30 proposed propose VERB b8515m62t1x 8 31 . . PUNCT