id	sid	tid	token	lemma	pos
b8515m62s7p	1	1	malaria	malaria	NOUN
b8515m62s7p	1	2	is	be	AUX
b8515m62s7p	1	3	a	a	DET
b8515m62s7p	1	4	devastating	devastating	ADJ
b8515m62s7p	1	5	infectious	infectious	ADJ
b8515m62s7p	1	6	disease	disease	NOUN
b8515m62s7p	1	7	that	that	PRON
b8515m62s7p	1	8	has	have	AUX
b8515m62s7p	1	9	caused	cause	VERB
b8515m62s7p	1	10	death	death	NOUN
b8515m62s7p	1	11	and	and	CCONJ
b8515m62s7p	1	12	debilitation	debilitation	NOUN
b8515m62s7p	1	13	for	for	ADP
b8515m62s7p	1	14	centuries	century	NOUN
b8515m62s7p	1	15	.	.	PUNCT
b8515m62s7p	2	1	it	it	PRON
b8515m62s7p	2	2	remains	remain	VERB
b8515m62s7p	2	3	a	a	DET
b8515m62s7p	2	4	globally	globally	ADV
b8515m62s7p	2	5	significant	significant	ADJ
b8515m62s7p	2	6	disease	disease	NOUN
b8515m62s7p	2	7	despite	despite	SCONJ
b8515m62s7p	2	8	relentless	relentless	ADJ
b8515m62s7p	2	9	efforts	effort	NOUN
b8515m62s7p	2	10	to	to	PART
b8515m62s7p	2	11	control	control	VERB
b8515m62s7p	2	12	it	it	PRON
b8515m62s7p	2	13	over	over	ADP
b8515m62s7p	2	14	the	the	DET
b8515m62s7p	2	15	last	last	ADJ
b8515m62s7p	2	16	century	century	NOUN
b8515m62s7p	2	17	.	.	PUNCT
b8515m62s7p	3	1	infections	infection	NOUN
b8515m62s7p	3	2	resulting	result	VERB
b8515m62s7p	3	3	from	from	ADP
b8515m62s7p	3	4	the	the	DET
b8515m62s7p	3	5	malaria	malaria	NOUN
b8515m62s7p	3	6	parasite	parasite	NOUN
b8515m62s7p	3	7	,	,	PUNCT
b8515m62s7p	3	8	plasmodium	plasmodium	ADJ
b8515m62s7p	3	9	falciparum	falciparum	NOUN
b8515m62s7p	3	10	,	,	PUNCT
b8515m62s7p	3	11	cause	cause	VERB
b8515m62s7p	3	12	approximately	approximately	ADV
b8515m62s7p	3	13	300500	300500	NUM
b8515m62s7p	3	14	million	million	NUM
b8515m62s7p	3	15	clinical	clinical	ADJ
b8515m62s7p	3	16	cases	case	NOUN
b8515m62s7p	3	17	and	and	CCONJ
b8515m62s7p	3	18	nearly	nearly	ADV
b8515m62s7p	3	19	a	a	DET
b8515m62s7p	3	20	million	million	NUM
b8515m62s7p	3	21	deaths	death	NOUN
b8515m62s7p	3	22	each	each	DET
b8515m62s7p	3	23	year	year	NOUN
b8515m62s7p	3	24	.	.	PUNCT
b8515m62s7p	4	1	disease	disease	NOUN
b8515m62s7p	4	2	control	control	NOUN
b8515m62s7p	4	3	has	have	AUX
b8515m62s7p	4	4	been	be	AUX
b8515m62s7p	4	5	confounded	confound	VERB
b8515m62s7p	4	6	by	by	ADP
b8515m62s7p	4	7	the	the	DET
b8515m62s7p	4	8	emergence	emergence	NOUN
b8515m62s7p	4	9	of	of	ADP
b8515m62s7p	4	10	multidrug	multidrug	NOUN
b8515m62s7p	4	11	resistant	resistant	ADJ
b8515m62s7p	4	12	(	(	PUNCT
b8515m62s7p	4	13	mdr	mdr	NOUN
b8515m62s7p	4	14	)	)	PUNCT
b8515m62s7p	4	15	parasites	parasite	NOUN
b8515m62s7p	4	16	.	.	PUNCT
b8515m62s7p	5	1	the	the	DET
b8515m62s7p	5	2	success	success	NOUN
b8515m62s7p	5	3	of	of	ADP
b8515m62s7p	5	4	the	the	DET
b8515m62s7p	5	5	parasite	parasite	NOUN
b8515m62s7p	5	6	in	in	ADP
b8515m62s7p	5	7	defeating	defeat	VERB
b8515m62s7p	5	8	eradication	eradication	NOUN
b8515m62s7p	5	9	and	and	CCONJ
b8515m62s7p	5	10	control	control	NOUN
b8515m62s7p	5	11	is	be	AUX
b8515m62s7p	5	12	largely	largely	ADV
b8515m62s7p	5	13	attributable	attributable	ADJ
b8515m62s7p	5	14	to	to	ADP
b8515m62s7p	5	15	its	its	PRON
b8515m62s7p	5	16	genetic	genetic	ADJ
b8515m62s7p	5	17	variability	variability	NOUN
b8515m62s7p	5	18	,	,	PUNCT
b8515m62s7p	5	19	which	which	PRON
b8515m62s7p	5	20	allows	allow	VERB
b8515m62s7p	5	21	the	the	DET
b8515m62s7p	5	22	parasite	parasite	NOUN
b8515m62s7p	5	23	to	to	PART
b8515m62s7p	5	24	overcome	overcome	VERB
b8515m62s7p	5	25	human	human	ADJ
b8515m62s7p	5	26	host	host	NOUN
b8515m62s7p	5	27	immunity	immunity	NOUN
b8515m62s7p	5	28	,	,	PUNCT
b8515m62s7p	5	29	and	and	CCONJ
b8515m62s7p	5	30	drug	drug	NOUN
b8515m62s7p	5	31	treatment	treatment	NOUN
b8515m62s7p	5	32	regimens	regimen	NOUN
b8515m62s7p	5	33	.	.	PUNCT
b8515m62s7p	6	1	recombination	recombination	NOUN
b8515m62s7p	6	2	is	be	AUX
b8515m62s7p	6	3	a	a	DET
b8515m62s7p	6	4	fundamental	fundamental	ADJ
b8515m62s7p	6	5	mechanism	mechanism	NOUN
b8515m62s7p	6	6	by	by	ADP
b8515m62s7p	6	7	which	which	PRON
b8515m62s7p	6	8	genetic	genetic	ADJ
b8515m62s7p	6	9	variation	variation	NOUN
b8515m62s7p	6	10	is	be	AUX
b8515m62s7p	6	11	introduced	introduce	VERB
b8515m62s7p	6	12	from	from	ADP
b8515m62s7p	6	13	the	the	DET
b8515m62s7p	6	14	parent	parent	NOUN
b8515m62s7p	6	15	to	to	ADP
b8515m62s7p	6	16	subsequent	subsequent	ADJ
b8515m62s7p	6	17	generations	generation	NOUN
b8515m62s7p	6	18	by	by	ADP
b8515m62s7p	6	19	reshuffling	reshuffle	VERB
b8515m62s7p	6	20	parent	parent	NOUN
b8515m62s7p	6	21	genome	genome	NOUN
b8515m62s7p	6	22	material	material	NOUN
b8515m62s7p	6	23	and	and	CCONJ
b8515m62s7p	6	24	breaks	break	VERB
b8515m62s7p	6	25	up	up	ADP
b8515m62s7p	6	26	linkage	linkage	NOUN
b8515m62s7p	6	27	between	between	ADP
b8515m62s7p	6	28	loci	locus	NOUN
b8515m62s7p	6	29	,	,	PUNCT
b8515m62s7p	6	30	allowing	allow	VERB
b8515m62s7p	6	31	for	for	ADP
b8515m62s7p	6	32	independent	independent	ADJ
b8515m62s7p	6	33	evolution	evolution	NOUN
b8515m62s7p	6	34	of	of	ADP
b8515m62s7p	6	35	sites	site	NOUN
b8515m62s7p	6	36	.	.	PUNCT
b8515m62s7p	7	1	knowledge	knowledge	NOUN
b8515m62s7p	7	2	of	of	ADP
b8515m62s7p	7	3	the	the	DET
b8515m62s7p	7	4	extent	extent	NOUN
b8515m62s7p	7	5	and	and	CCONJ
b8515m62s7p	7	6	distribution	distribution	NOUN
b8515m62s7p	7	7	of	of	ADP
b8515m62s7p	7	8	genetic	genetic	ADJ
b8515m62s7p	7	9	variation	variation	NOUN
b8515m62s7p	7	10	,	,	PUNCT
b8515m62s7p	7	11	as	as	ADV
b8515m62s7p	7	12	well	well	ADV
b8515m62s7p	7	13	as	as	ADP
b8515m62s7p	7	14	the	the	DET
b8515m62s7p	7	15	mechanisms	mechanism	NOUN
b8515m62s7p	7	16	that	that	PRON
b8515m62s7p	7	17	generate	generate	VERB
b8515m62s7p	7	18	variation	variation	NOUN
b8515m62s7p	7	19	is	be	AUX
b8515m62s7p	7	20	fundamental	fundamental	ADJ
b8515m62s7p	7	21	to	to	ADP
b8515m62s7p	7	22	understanding	understand	VERB
b8515m62s7p	7	23	the	the	DET
b8515m62s7p	7	24	evolution	evolution	NOUN
b8515m62s7p	7	25	of	of	ADP
b8515m62s7p	7	26	parasite	parasite	NOUN
b8515m62s7p	7	27	phenotypes	phenotype	NOUN
b8515m62s7p	7	28	,	,	PUNCT
b8515m62s7p	7	29	including	include	VERB
b8515m62s7p	7	30	drug	drug	NOUN
b8515m62s7p	7	31	resistance	resistance	NOUN
b8515m62s7p	7	32	,	,	PUNCT
b8515m62s7p	7	33	prevalence	prevalence	NOUN
b8515m62s7p	7	34	and	and	CCONJ
b8515m62s7p	7	35	severity	severity	NOUN
b8515m62s7p	7	36	of	of	ADP
b8515m62s7p	7	37	the	the	DET
b8515m62s7p	7	38	disease	disease	NOUN
b8515m62s7p	7	39	in	in	ADP
b8515m62s7p	7	40	humans	human	NOUN
b8515m62s7p	7	41	.	.	PUNCT
b8515m62s7p	8	1	this	this	DET
b8515m62s7p	8	2	dissertation	dissertation	NOUN
b8515m62s7p	8	3	focused	focus	VERB
b8515m62s7p	8	4	on	on	ADP
b8515m62s7p	8	5	revealing	reveal	VERB
b8515m62s7p	8	6	the	the	DET
b8515m62s7p	8	7	role	role	NOUN
b8515m62s7p	8	8	of	of	ADP
b8515m62s7p	8	9	recombination	recombination	NOUN
b8515m62s7p	8	10	on	on	ADP
b8515m62s7p	8	11	the	the	DET
b8515m62s7p	8	12	genetic	genetic	ADJ
b8515m62s7p	8	13	variability	variability	NOUN
b8515m62s7p	8	14	of	of	ADP
b8515m62s7p	8	15	the	the	DET
b8515m62s7p	8	16	malaria	malaria	NOUN
b8515m62s7p	8	17	parasite	parasite	NOUN
b8515m62s7p	8	18	.	.	PUNCT
b8515m62s7p	9	1	we	we	PRON
b8515m62s7p	9	2	used	use	VERB
b8515m62s7p	9	3	an	an	DET
b8515m62s7p	9	4	experimental	experimental	ADJ
b8515m62s7p	9	5	system	system	NOUN
b8515m62s7p	9	6	based	base	VERB
b8515m62s7p	9	7	on	on	ADP
b8515m62s7p	9	8	a	a	DET
b8515m62s7p	9	9	well	well	ADV
b8515m62s7p	9	10	-	-	PUNCT
b8515m62s7p	9	11	known	know	VERB
b8515m62s7p	9	12	genetic	genetic	ADJ
b8515m62s7p	9	13	cross	cross	NOUN
b8515m62s7p	9	14	,	,	PUNCT
b8515m62s7p	9	15	hb3ìä	hb3ìä	SPACE
b8515m62s7p	9	16	'	'	PUNCT
b8515m62s7p	9	17	dd2	dd2	NOUN
b8515m62s7p	9	18	,	,	PUNCT
b8515m62s7p	9	19	to	to	PART
b8515m62s7p	9	20	directly	directly	ADV
b8515m62s7p	9	21	observe	observe	VERB
b8515m62s7p	9	22	the	the	DET
b8515m62s7p	9	23	products	product	NOUN
b8515m62s7p	9	24	of	of	ADP
b8515m62s7p	9	25	recombination	recombination	NOUN
b8515m62s7p	9	26	.	.	PUNCT
b8515m62s7p	10	1	in	in	ADP
b8515m62s7p	10	2	the	the	DET
b8515m62s7p	10	3	context	context	NOUN
b8515m62s7p	10	4	of	of	ADP
b8515m62s7p	10	5	the	the	DET
b8515m62s7p	10	6	genetic	genetic	ADJ
b8515m62s7p	10	7	cross	cross	PROPN
b8515m62s7p	10	8	,	,	PUNCT
b8515m62s7p	10	9	we	we	PRON
b8515m62s7p	10	10	carried	carry	VERB
b8515m62s7p	10	11	out	out	ADP
b8515m62s7p	10	12	linkage	linkage	NOUN
b8515m62s7p	10	13	analysis	analysis	NOUN
b8515m62s7p	10	14	,	,	PUNCT
b8515m62s7p	10	15	detected	detect	VERB
b8515m62s7p	10	16	the	the	DET
b8515m62s7p	10	17	fine	fine	ADJ
b8515m62s7p	10	18	structure	structure	NOUN
b8515m62s7p	10	19	of	of	ADP
b8515m62s7p	10	20	recombinant	recombinant	ADJ
b8515m62s7p	10	21	products	product	NOUN
b8515m62s7p	10	22	,	,	PUNCT
b8515m62s7p	10	23	and	and	CCONJ
b8515m62s7p	10	24	revealed	reveal	VERB
b8515m62s7p	10	25	the	the	DET
b8515m62s7p	10	26	dynamics	dynamic	NOUN
b8515m62s7p	10	27	and	and	CCONJ
b8515m62s7p	10	28	mechanisms	mechanism	NOUN
b8515m62s7p	10	29	of	of	ADP
b8515m62s7p	10	30	copy	copy	NOUN
b8515m62s7p	10	31	number	number	NOUN
b8515m62s7p	10	32	variation	variation	NOUN
b8515m62s7p	10	33	(	(	PUNCT
b8515m62s7p	10	34	cnv	cnv	PROPN
b8515m62s7p	10	35	)	)	PUNCT
b8515m62s7p	10	36	inheritance	inheritance	NOUN
b8515m62s7p	10	37	in	in	ADP
b8515m62s7p	10	38	the	the	DET
b8515m62s7p	10	39	parasite	parasite	NOUN
b8515m62s7p	10	40	.	.	PUNCT
b8515m62s7p	11	1	this	this	DET
b8515m62s7p	11	2	approach	approach	NOUN
b8515m62s7p	11	3	allowed	allow	VERB
b8515m62s7p	11	4	for	for	ADP
b8515m62s7p	11	5	a	a	DET
b8515m62s7p	11	6	unique	unique	ADJ
b8515m62s7p	11	7	and	and	CCONJ
b8515m62s7p	11	8	previously	previously	ADV
b8515m62s7p	11	9	unappreciated	unappreciated	ADJ
b8515m62s7p	11	10	glimpse	glimpse	NOUN
b8515m62s7p	11	11	in	in	ADP
b8515m62s7p	11	12	to	to	ADP
b8515m62s7p	11	13	the	the	DET
b8515m62s7p	11	14	repertoire	repertoire	NOUN
b8515m62s7p	11	15	of	of	ADP
b8515m62s7p	11	16	genetic	genetic	ADJ
b8515m62s7p	11	17	variability	variability	NOUN
b8515m62s7p	11	18	that	that	PRON
b8515m62s7p	11	19	is	be	AUX
b8515m62s7p	11	20	generated	generate	VERB
b8515m62s7p	11	21	within	within	ADP
b8515m62s7p	11	22	a	a	DET
b8515m62s7p	11	23	life	life	NOUN
b8515m62s7p	11	24	cycle	cycle	NOUN
b8515m62s7p	11	25	of	of	ADP
b8515m62s7p	11	26	the	the	DET
b8515m62s7p	11	27	parasite	parasite	NOUN
b8515m62s7p	11	28	via	via	ADP
b8515m62s7p	11	29	recombination	recombination	NOUN
b8515m62s7p	11	30	.	.	PUNCT
b8515m62s7p	12	1	we	we	PRON
b8515m62s7p	12	2	demonstrated	demonstrate	VERB
b8515m62s7p	12	3	that	that	SCONJ
b8515m62s7p	12	4	combining	combine	VERB
b8515m62s7p	12	5	linkage	linkage	NOUN
b8515m62s7p	12	6	maps	map	NOUN
b8515m62s7p	12	7	from	from	ADP
b8515m62s7p	12	8	different	different	ADJ
b8515m62s7p	12	9	mapping	mapping	NOUN
b8515m62s7p	12	10	populations	population	NOUN
b8515m62s7p	12	11	of	of	ADP
b8515m62s7p	12	12	p.	p.	PROPN
b8515m62s7p	12	13	falciparum	falciparum	NOUN
b8515m62s7p	12	14	strains	strain	VERB
b8515m62s7p	12	15	with	with	ADP
b8515m62s7p	12	16	genome	genome	NOUN
b8515m62s7p	12	17	sequence	sequence	NOUN
b8515m62s7p	12	18	information	information	NOUN
b8515m62s7p	12	19	can	can	AUX
b8515m62s7p	12	20	refine	refine	VERB
b8515m62s7p	12	21	existing	exist	VERB
b8515m62s7p	12	22	maps	map	NOUN
b8515m62s7p	12	23	,	,	PUNCT
b8515m62s7p	12	24	increase	increase	VERB
b8515m62s7p	12	25	map	map	NOUN
b8515m62s7p	12	26	accuracy	accuracy	NOUN
b8515m62s7p	12	27	,	,	PUNCT
b8515m62s7p	12	28	inform	inform	VERB
b8515m62s7p	12	29	genome	genome	NOUN
b8515m62s7p	12	30	assemblies	assembly	NOUN
b8515m62s7p	12	31	,	,	PUNCT
b8515m62s7p	12	32	and	and	CCONJ
b8515m62s7p	12	33	highlight	highlight	VERB
b8515m62s7p	12	34	key	key	ADJ
b8515m62s7p	12	35	aspects	aspect	NOUN
b8515m62s7p	12	36	of	of	ADP
b8515m62s7p	12	37	the	the	DET
b8515m62s7p	12	38	biology	biology	NOUN
b8515m62s7p	12	39	of	of	ADP
b8515m62s7p	12	40	recombination	recombination	NOUN
b8515m62s7p	12	41	in	in	ADP
b8515m62s7p	12	42	the	the	DET
b8515m62s7p	12	43	parasite	parasite	NOUN
b8515m62s7p	12	44	.	.	PUNCT
b8515m62s7p	13	1	these	these	DET
b8515m62s7p	13	2	observations	observation	NOUN
b8515m62s7p	13	3	propelled	propel	VERB
b8515m62s7p	13	4	subsequent	subsequent	ADJ
b8515m62s7p	13	5	work	work	NOUN
b8515m62s7p	13	6	to	to	PART
b8515m62s7p	13	7	evaluate	evaluate	VERB
b8515m62s7p	13	8	the	the	DET
b8515m62s7p	13	9	genome	genome	NOUN
b8515m62s7p	13	10	-	-	PUNCT
b8515m62s7p	13	11	wide	wide	ADJ
b8515m62s7p	13	12	distribution	distribution	NOUN
b8515m62s7p	13	13	of	of	ADP
b8515m62s7p	13	14	recombination	recombination	NOUN
b8515m62s7p	13	15	at	at	ADP
b8515m62s7p	13	16	an	an	DET
b8515m62s7p	13	17	even	even	ADV
b8515m62s7p	13	18	higher	high	ADJ
b8515m62s7p	13	19	marker	marker	NOUN
b8515m62s7p	13	20	density	density	NOUN
b8515m62s7p	13	21	.	.	PUNCT
b8515m62s7p	14	1	we	we	PRON
b8515m62s7p	14	2	built	build	VERB
b8515m62s7p	14	3	on	on	ADP
b8515m62s7p	14	4	the	the	DET
b8515m62s7p	14	5	information	information	NOUN
b8515m62s7p	14	6	on	on	ADP
b8515m62s7p	14	7	linkage	linkage	NOUN
b8515m62s7p	14	8	analysis	analysis	NOUN
b8515m62s7p	14	9	and	and	CCONJ
b8515m62s7p	14	10	used	use	VERB
b8515m62s7p	14	11	two	two	NUM
b8515m62s7p	14	12	sibling	sible	VERB
b8515m62s7p	14	13	parasite	parasite	NOUN
b8515m62s7p	14	14	clones	clone	NOUN
b8515m62s7p	14	15	from	from	ADP
b8515m62s7p	14	16	the	the	DET
b8515m62s7p	14	17	hb3	hb3	NOUN
b8515m62s7p	14	18	ìä	ìä	NOUN
b8515m62s7p	14	19	'	'	PUNCT
b8515m62s7p	14	20	dd2	dd2	NOUN
b8515m62s7p	14	21	that	that	PRON
b8515m62s7p	14	22	had	have	VERB
b8515m62s7p	14	23	a	a	DET
b8515m62s7p	14	24	high	high	ADJ
b8515m62s7p	14	25	number	number	NOUN
b8515m62s7p	14	26	of	of	ADP
b8515m62s7p	14	27	crossovers	crossover	NOUN
b8515m62s7p	14	28	(	(	PUNCT
b8515m62s7p	14	29	cos	cos	PROPN
b8515m62s7p	14	30	)	)	PUNCT
b8515m62s7p	14	31	to	to	PART
b8515m62s7p	14	32	describe	describe	VERB
b8515m62s7p	14	33	a	a	DET
b8515m62s7p	14	34	method	method	NOUN
b8515m62s7p	14	35	to	to	PART
b8515m62s7p	14	36	detect	detect	VERB
b8515m62s7p	14	37	genomewide	genomewide	ADJ
b8515m62s7p	14	38	distribution	distribution	NOUN
b8515m62s7p	14	39	of	of	ADP
b8515m62s7p	14	40	cos	cos	PROPN
b8515m62s7p	14	41	,	,	PUNCT
b8515m62s7p	14	42	non	non	PROPN
b8515m62s7p	14	43	-	-	ADJ
b8515m62s7p	14	44	crossovers(ncos	crossovers(ncos	PROPN
b8515m62s7p	14	45	)	)	PUNCT
b8515m62s7p	14	46	and	and	CCONJ
b8515m62s7p	14	47	gene	gene	NOUN
b8515m62s7p	14	48	conversions	conversion	NOUN
b8515m62s7p	14	49	(	(	PUNCT
b8515m62s7p	14	50	gcs	gcs	PROPN
b8515m62s7p	14	51	)	)	PUNCT
b8515m62s7p	14	52	.	.	PUNCT
b8515m62s7p	15	1	this	this	DET
b8515m62s7p	15	2	study	study	NOUN
b8515m62s7p	15	3	was	be	AUX
b8515m62s7p	15	4	the	the	DET
b8515m62s7p	15	5	first	first	ADJ
b8515m62s7p	15	6	to	to	PART
b8515m62s7p	15	7	sequence	sequence	NOUN
b8515m62s7p	15	8	progeny	progeny	NOUN
b8515m62s7p	15	9	clones	clone	NOUN
b8515m62s7p	15	10	to	to	PART
b8515m62s7p	15	11	capture	capture	VERB
b8515m62s7p	15	12	high	high	ADJ
b8515m62s7p	15	13	resolution	resolution	NOUN
b8515m62s7p	15	14	information	information	NOUN
b8515m62s7p	15	15	on	on	ADP
b8515m62s7p	15	16	cos	cos	PROPN
b8515m62s7p	15	17	,	,	PUNCT
b8515m62s7p	15	18	ncos	nco	NOUN
b8515m62s7p	15	19	and	and	CCONJ
b8515m62s7p	15	20	genetic	genetic	ADJ
b8515m62s7p	15	21	variation	variation	NOUN
b8515m62s7p	15	22	in	in	ADP
b8515m62s7p	15	23	malaria	malaria	NOUN
b8515m62s7p	15	24	parasites	parasite	NOUN
b8515m62s7p	15	25	.	.	PUNCT
b8515m62s7p	16	1	the	the	DET
b8515m62s7p	16	2	work	work	NOUN
b8515m62s7p	16	3	emphasized	emphasize	VERB
b8515m62s7p	16	4	the	the	DET
b8515m62s7p	16	5	importance	importance	NOUN
b8515m62s7p	16	6	of	of	ADP
b8515m62s7p	16	7	nco	nco	PROPN
b8515m62s7p	16	8	/	/	SYM
b8515m62s7p	16	9	gcs	gcs	NOUN
b8515m62s7p	16	10	in	in	ADP
b8515m62s7p	16	11	the	the	DET
b8515m62s7p	16	12	linkage	linkage	NOUN
b8515m62s7p	16	13	and	and	CCONJ
b8515m62s7p	16	14	haplotype	haplotype	NOUN
b8515m62s7p	16	15	analysis	analysis	NOUN
b8515m62s7p	16	16	of	of	ADP
b8515m62s7p	16	17	malaria	malaria	NOUN
b8515m62s7p	16	18	parasites	parasite	NOUN
b8515m62s7p	16	19	and	and	CCONJ
b8515m62s7p	16	20	the	the	DET
b8515m62s7p	16	21	need	need	NOUN
b8515m62s7p	16	22	for	for	ADP
b8515m62s7p	16	23	the	the	DET
b8515m62s7p	16	24	description	description	NOUN
b8515m62s7p	16	25	of	of	ADP
b8515m62s7p	16	26	a	a	DET
b8515m62s7p	16	27	genome	genome	NOUN
b8515m62s7p	16	28	-	-	PUNCT
b8515m62s7p	16	29	wide	wide	ADJ
b8515m62s7p	16	30	rate	rate	NOUN
b8515m62s7p	16	31	of	of	ADP
b8515m62s7p	16	32	gcs	gcs	NOUN
b8515m62s7p	16	33	for	for	ADP
b8515m62s7p	16	34	the	the	DET
b8515m62s7p	16	35	species	specie	NOUN
b8515m62s7p	16	36	to	to	PART
b8515m62s7p	16	37	advance	advance	VERB
b8515m62s7p	16	38	ongoing	ongoing	ADJ
b8515m62s7p	16	39	efforts	effort	NOUN
b8515m62s7p	16	40	in	in	ADP
b8515m62s7p	16	41	haplotype	haplotype	NOUN
b8515m62s7p	16	42	analysis	analysis	NOUN
b8515m62s7p	16	43	and	and	CCONJ
b8515m62s7p	16	44	to	to	PART
b8515m62s7p	16	45	improve	improve	VERB
b8515m62s7p	16	46	the	the	DET
b8515m62s7p	16	47	accuracy	accuracy	NOUN
b8515m62s7p	16	48	of	of	ADP
b8515m62s7p	16	49	genome	genome	NOUN
b8515m62s7p	16	50	-	-	PUNCT
b8515m62s7p	16	51	wide	wide	ADJ
b8515m62s7p	16	52	association	association	NOUN
b8515m62s7p	16	53	studies	study	NOUN
b8515m62s7p	16	54	(	(	PUNCT
b8515m62s7p	16	55	gwas	gwas	PROPN
b8515m62s7p	16	56	)	)	PUNCT
b8515m62s7p	16	57	.	.	PUNCT
b8515m62s7p	17	1	we	we	PRON
b8515m62s7p	17	2	also	also	ADV
b8515m62s7p	17	3	argued	argue	VERB
b8515m62s7p	17	4	that	that	SCONJ
b8515m62s7p	17	5	it	it	PRON
b8515m62s7p	17	6	is	be	AUX
b8515m62s7p	17	7	essential	essential	ADJ
b8515m62s7p	17	8	to	to	PART
b8515m62s7p	17	9	combine	combine	VERB
b8515m62s7p	17	10	linkage	linkage	NOUN
b8515m62s7p	17	11	analysis	analysis	NOUN
b8515m62s7p	17	12	and	and	CCONJ
b8515m62s7p	17	13	genome	genome	NOUN
b8515m62s7p	17	14	-	-	PUNCT
b8515m62s7p	17	15	wide	wide	ADJ
b8515m62s7p	17	16	distributions	distribution	NOUN
b8515m62s7p	17	17	of	of	ADP
b8515m62s7p	17	18	cnvs	cnvs	PROPN
b8515m62s7p	17	19	to	to	PART
b8515m62s7p	17	20	determine	determine	VERB
b8515m62s7p	17	21	cnv	cnv	PROPN
b8515m62s7p	17	22	behavior	behavior	NOUN
b8515m62s7p	17	23	,	,	PUNCT
b8515m62s7p	17	24	distributions	distribution	NOUN
b8515m62s7p	17	25	and	and	CCONJ
b8515m62s7p	17	26	frequencies	frequency	NOUN
b8515m62s7p	17	27	across	across	ADP
b8515m62s7p	17	28	genomes	genome	NOUN
b8515m62s7p	17	29	to	to	PART
b8515m62s7p	17	30	understand	understand	VERB
b8515m62s7p	17	31	the	the	DET
b8515m62s7p	17	32	origins	origin	NOUN
b8515m62s7p	17	33	of	of	ADP
b8515m62s7p	17	34	cnv	cnv	NOUN
b8515m62s7p	17	35	in	in	ADP
b8515m62s7p	17	36	both	both	CCONJ
b8515m62s7p	17	37	evolutionary	evolutionary	ADJ
b8515m62s7p	17	38	and	and	CCONJ
b8515m62s7p	17	39	generational	generational	ADJ
b8515m62s7p	17	40	time	time	NOUN
b8515m62s7p	17	41	frames	frame	NOUN
b8515m62s7p	17	42	.	.	PUNCT
b8515m62s7p	18	1	we	we	PRON
b8515m62s7p	18	2	revealed	reveal	VERB
b8515m62s7p	18	3	that	that	SCONJ
b8515m62s7p	18	4	cnvs	cnvs	PROPN
b8515m62s7p	18	5	are	be	AUX
b8515m62s7p	18	6	a	a	DET
b8515m62s7p	18	7	significant	significant	ADJ
b8515m62s7p	18	8	source	source	NOUN
b8515m62s7p	18	9	of	of	ADP
b8515m62s7p	18	10	segregating	segregate	VERB
b8515m62s7p	18	11	and	and	CCONJ
b8515m62s7p	18	12	de	de	X
b8515m62s7p	18	13	novo	novo	PROPN
b8515m62s7p	18	14	genome	genome	NOUN
b8515m62s7p	18	15	variation	variation	NOUN
b8515m62s7p	18	16	.	.	PUNCT
b8515m62s7p	19	1	the	the	DET
b8515m62s7p	19	2	study	study	NOUN
b8515m62s7p	19	3	highlighted	highlight	VERB
b8515m62s7p	19	4	that	that	SCONJ
b8515m62s7p	19	5	the	the	DET
b8515m62s7p	19	6	rate	rate	NOUN
b8515m62s7p	19	7	of	of	ADP
b8515m62s7p	19	8	de	de	X
b8515m62s7p	19	9	novo	novo	ADP
b8515m62s7p	19	10	cnv	cnv	PROPN
b8515m62s7p	19	11	may	may	AUX
b8515m62s7p	19	12	be	be	AUX
b8515m62s7p	19	13	higher	high	ADJ
b8515m62s7p	19	14	than	than	SCONJ
b8515m62s7p	19	15	expected	expect	VERB
b8515m62s7p	19	16	in	in	ADP
b8515m62s7p	19	17	p.	p.	PROPN
b8515m62s7p	19	18	falciparum	falciparum	NOUN
b8515m62s7p	19	19	and	and	CCONJ
b8515m62s7p	19	20	that	that	SCONJ
b8515m62s7p	19	21	both	both	PRON
b8515m62s7p	19	22	by	by	NOUN
b8515m62s7p	19	23	-	-	PUNCT
b8515m62s7p	19	24	products	product	NOUN
b8515m62s7p	19	25	of	of	ADP
b8515m62s7p	19	26	recombination	recombination	NOUN
b8515m62s7p	19	27	,	,	PUNCT
b8515m62s7p	19	28	cos	cos	PROPN
b8515m62s7p	19	29	and	and	CCONJ
b8515m62s7p	19	30	nco	nco	PROPN
b8515m62s7p	19	31	/	/	SYM
b8515m62s7p	19	32	gcs	gcs	PROPN
b8515m62s7p	19	33	,	,	PUNCT
b8515m62s7p	19	34	can	can	AUX
b8515m62s7p	19	35	not	not	PART
b8515m62s7p	19	36	only	only	ADV
b8515m62s7p	19	37	produce	produce	VERB
b8515m62s7p	19	38	de	de	X
b8515m62s7p	19	39	novo	novo	PROPN
b8515m62s7p	19	40	cnvs	cnvs	PROPN
b8515m62s7p	19	41	,	,	PUNCT
b8515m62s7p	19	42	but	but	CCONJ
b8515m62s7p	19	43	also	also	ADV
b8515m62s7p	19	44	lead	lead	VERB
b8515m62s7p	19	45	to	to	ADP
b8515m62s7p	19	46	loss	loss	NOUN
b8515m62s7p	19	47	or	or	CCONJ
b8515m62s7p	19	48	gain	gain	NOUN
b8515m62s7p	19	49	of	of	ADP
b8515m62s7p	19	50	copies	copy	NOUN
b8515m62s7p	19	51	at	at	ADP
b8515m62s7p	19	52	an	an	DET
b8515m62s7p	19	53	already	already	ADV
b8515m62s7p	19	54	existing	exist	VERB
b8515m62s7p	19	55	cnv	cnv	PROPN
b8515m62s7p	19	56	locus	locus	NOUN
b8515m62s7p	19	57	.	.	PUNCT
b8515m62s7p	20	1	in	in	ADP
b8515m62s7p	20	2	conclusion	conclusion	NOUN
b8515m62s7p	20	3	,	,	PUNCT
b8515m62s7p	20	4	this	this	DET
b8515m62s7p	20	5	doctoral	doctoral	ADJ
b8515m62s7p	20	6	thesis	thesis	NOUN
b8515m62s7p	20	7	emphasized	emphasize	VERB
b8515m62s7p	20	8	the	the	DET
b8515m62s7p	20	9	significance	significance	NOUN
b8515m62s7p	20	10	of	of	ADP
b8515m62s7p	20	11	recombination	recombination	NOUN
b8515m62s7p	20	12	as	as	ADP
b8515m62s7p	20	13	a	a	DET
b8515m62s7p	20	14	central	central	ADJ
b8515m62s7p	20	15	mechanism	mechanism	NOUN
b8515m62s7p	20	16	generating	generate	VERB
b8515m62s7p	20	17	several	several	ADJ
b8515m62s7p	20	18	distinct	distinct	ADJ
b8515m62s7p	20	19	classes	class	NOUN
b8515m62s7p	20	20	of	of	ADP
b8515m62s7p	20	21	genetic	genetic	ADJ
b8515m62s7p	20	22	variants	variant	NOUN
b8515m62s7p	20	23	in	in	ADP
b8515m62s7p	20	24	p.	p.	PROPN
b8515m62s7p	20	25	falciparum	falciparum	NOUN
b8515m62s7p	20	26	,	,	PUNCT
b8515m62s7p	20	27	ranging	range	VERB
b8515m62s7p	20	28	from	from	ADP
b8515m62s7p	20	29	reshuffling	reshuffling	NOUN
b8515m62s7p	20	30	of	of	ADP
b8515m62s7p	20	31	parent	parent	NOUN
b8515m62s7p	20	32	genomes	genome	NOUN
b8515m62s7p	20	33	to	to	ADP
b8515m62s7p	20	34	gcs	gcs	PROPN
b8515m62s7p	20	35	to	to	PART
b8515m62s7p	20	36	genome	genome	VERB
b8515m62s7p	20	37	structural	structural	ADJ
b8515m62s7p	20	38	variants	variant	NOUN
b8515m62s7p	20	39	.	.	PUNCT
b8515m62s7p	21	1	these	these	DET
b8515m62s7p	21	2	studies	study	NOUN
b8515m62s7p	21	3	are	be	AUX
b8515m62s7p	21	4	fundamental	fundamental	ADJ
b8515m62s7p	21	5	contributions	contribution	NOUN
b8515m62s7p	21	6	to	to	ADP
b8515m62s7p	21	7	establishing	establish	VERB
b8515m62s7p	21	8	a	a	DET
b8515m62s7p	21	9	framework	framework	NOUN
b8515m62s7p	21	10	for	for	ADP
b8515m62s7p	21	11	ongoing	ongoing	ADJ
b8515m62s7p	21	12	studies	study	NOUN
b8515m62s7p	21	13	of	of	ADP
b8515m62s7p	21	14	recombination	recombination	NOUN
b8515m62s7p	21	15	and	and	CCONJ
b8515m62s7p	21	16	the	the	DET
b8515m62s7p	21	17	mechanisms	mechanism	NOUN
b8515m62s7p	21	18	of	of	ADP
b8515m62s7p	21	19	genome	genome	NOUN
b8515m62s7p	21	20	structural	structural	ADJ
b8515m62s7p	21	21	variation	variation	NOUN
b8515m62s7p	21	22	in	in	ADP
b8515m62s7p	21	23	malaria	malaria	NOUN
b8515m62s7p	21	24	parasites	parasite	NOUN
b8515m62s7p	21	25	.	.	PUNCT