id sid tid token lemma pos 9g54xg97m8b 1 1 ischemic ischemic ADJ 9g54xg97m8b 1 2 heart heart NOUN 9g54xg97m8b 1 3 disease disease NOUN 9g54xg97m8b 1 4 perennially perennially ADV 9g54xg97m8b 1 5 is be AUX 9g54xg97m8b 1 6 the the DET 9g54xg97m8b 1 7 most most ADV 9g54xg97m8b 1 8 common common ADJ 9g54xg97m8b 1 9 cause cause NOUN 9g54xg97m8b 1 10 of of ADP 9g54xg97m8b 1 11 death death NOUN 9g54xg97m8b 1 12 in in ADP 9g54xg97m8b 1 13 the the DET 9g54xg97m8b 1 14 us us PROPN 9g54xg97m8b 1 15 and and CCONJ 9g54xg97m8b 1 16 the the DET 9g54xg97m8b 1 17 world world NOUN 9g54xg97m8b 1 18 . . PUNCT 9g54xg97m8b 2 1 myocardial myocardial ADJ 9g54xg97m8b 2 2 infarction infarction NOUN 9g54xg97m8b 2 3 ( ( PUNCT 9g54xg97m8b 2 4 mi mi PROPN 9g54xg97m8b 2 5 ) ) PUNCT 9g54xg97m8b 2 6 is be AUX 9g54xg97m8b 2 7 the the DET 9g54xg97m8b 2 8 most most ADV 9g54xg97m8b 2 9 lethal lethal ADJ 9g54xg97m8b 2 10 and and CCONJ 9g54xg97m8b 2 11 rapid rapid ADJ 9g54xg97m8b 2 12 pathology pathology NOUN 9g54xg97m8b 2 13 in in ADP 9g54xg97m8b 2 14 this this DET 9g54xg97m8b 2 15 category category NOUN 9g54xg97m8b 2 16 and and CCONJ 9g54xg97m8b 2 17 requires require VERB 9g54xg97m8b 2 18 rapid rapid ADJ 9g54xg97m8b 2 19 diagnosis diagnosis NOUN 9g54xg97m8b 2 20 , , PUNCT 9g54xg97m8b 2 21 time time NOUN 9g54xg97m8b 2 22 - - PUNCT 9g54xg97m8b 2 23 critical critical ADJ 9g54xg97m8b 2 24 treatment treatment NOUN 9g54xg97m8b 2 25 , , PUNCT 9g54xg97m8b 2 26 and and CCONJ 9g54xg97m8b 2 27 disease disease NOUN 9g54xg97m8b 2 28 progression progression NOUN 9g54xg97m8b 2 29 monitoring monitoring NOUN 9g54xg97m8b 2 30 . . PUNCT 9g54xg97m8b 3 1 herein herein ADV 9g54xg97m8b 3 2 a a DET 9g54xg97m8b 3 3 process process NOUN 9g54xg97m8b 3 4 to to PART 9g54xg97m8b 3 5 mimic mimic VERB 9g54xg97m8b 3 6 the the DET 9g54xg97m8b 3 7 mi mi PROPN 9g54xg97m8b 3 8 experience experience NOUN 9g54xg97m8b 3 9 in in ADP 9g54xg97m8b 3 10 vitro vitro X 9g54xg97m8b 3 11 through through ADP 9g54xg97m8b 3 12 iteratively iteratively ADV 9g54xg97m8b 3 13 more more ADV 9g54xg97m8b 3 14 complex complex ADJ 9g54xg97m8b 3 15 culture culture NOUN 9g54xg97m8b 3 16 models model NOUN 9g54xg97m8b 3 17 is be AUX 9g54xg97m8b 3 18 described describe VERB 9g54xg97m8b 3 19 in in ADP 9g54xg97m8b 3 20 lieu lieu NOUN 9g54xg97m8b 3 21 of of ADP 9g54xg97m8b 3 22 a a DET 9g54xg97m8b 3 23 microrna microrna PROPN 9g54xg97m8b 3 24 ( ( PUNCT 9g54xg97m8b 3 25 mir mir PROPN 9g54xg97m8b 3 26 ) ) PUNCT 9g54xg97m8b 3 27 detection detection NOUN 9g54xg97m8b 3 28 platform platform NOUN 9g54xg97m8b 3 29 and and CCONJ 9g54xg97m8b 3 30 extracellular extracellular ADJ 9g54xg97m8b 3 31 vesicle vesicle NOUN 9g54xg97m8b 3 32 ( ( PUNCT 9g54xg97m8b 3 33 ev ev INTJ 9g54xg97m8b 3 34 ) ) PUNCT 9g54xg97m8b 3 35 lysis lysis NOUN 9g54xg97m8b 3 36 chip chip NOUN 9g54xg97m8b 3 37 . . PUNCT 9g54xg97m8b 4 1 this this DET 9g54xg97m8b 4 2 platform platform NOUN 9g54xg97m8b 4 3 will will AUX 9g54xg97m8b 4 4 be be AUX 9g54xg97m8b 4 5 compared compare VERB 9g54xg97m8b 4 6 against against ADP 9g54xg97m8b 4 7 clinical clinical ADJ 9g54xg97m8b 4 8 plasma plasma NOUN 9g54xg97m8b 4 9 samples sample NOUN 9g54xg97m8b 4 10 to to PART 9g54xg97m8b 4 11 better well ADV 9g54xg97m8b 4 12 inform inform VERB 9g54xg97m8b 4 13 the the DET 9g54xg97m8b 4 14 iterative iterative ADJ 9g54xg97m8b 4 15 process process NOUN 9g54xg97m8b 4 16 as as ADV 9g54xg97m8b 4 17 well well ADV 9g54xg97m8b 4 18 as as ADP 9g54xg97m8b 4 19 study study VERB 9g54xg97m8b 4 20 the the DET 9g54xg97m8b 4 21 temporal temporal ADJ 9g54xg97m8b 4 22 mir mir PROPN 9g54xg97m8b 4 23 transients transient NOUN 9g54xg97m8b 4 24 in in ADP 9g54xg97m8b 4 25 st st PROPN 9g54xg97m8b 4 26 - - PUNCT 9g54xg97m8b 4 27 elevated elevated ADJ 9g54xg97m8b 4 28 mi mi PROPN 9g54xg97m8b 4 29 ( ( PUNCT 9g54xg97m8b 4 30 stemi stemi PROPN 9g54xg97m8b 4 31 ) ) PUNCT 9g54xg97m8b 4 32 and and CCONJ 9g54xg97m8b 4 33 how how SCONJ 9g54xg97m8b 4 34 these these PRON 9g54xg97m8b 4 35 compare compare VERB 9g54xg97m8b 4 36 to to ADP 9g54xg97m8b 4 37 mir mir PROPN 9g54xg97m8b 4 38 profiles profile NOUN 9g54xg97m8b 4 39 in in ADP 9g54xg97m8b 4 40 coronary coronary ADJ 9g54xg97m8b 4 41 artery artery NOUN 9g54xg97m8b 4 42 disease disease NOUN 9g54xg97m8b 4 43 ( ( PUNCT 9g54xg97m8b 4 44 cad).of cad).of VERB 9g54xg97m8b 4 45 the the DET 9g54xg97m8b 4 46 mirs mirs PROPN 9g54xg97m8b 4 47 examined examine VERB 9g54xg97m8b 4 48 mir-1 mir-1 SPACE 9g54xg97m8b 4 49 , , PUNCT 9g54xg97m8b 4 50 208 208 NUM 9g54xg97m8b 4 51 , , PUNCT 9g54xg97m8b 4 52 and and CCONJ 9g54xg97m8b 4 53 499 499 NUM 9g54xg97m8b 4 54 exhibit exhibit VERB 9g54xg97m8b 4 55 the the DET 9g54xg97m8b 4 56 most most ADV 9g54xg97m8b 4 57 promising promising ADJ 9g54xg97m8b 4 58 indicators indicator NOUN 9g54xg97m8b 4 59 of of ADP 9g54xg97m8b 4 60 myocardial myocardial ADJ 9g54xg97m8b 4 61 irregularities irregularity NOUN 9g54xg97m8b 4 62 . . PUNCT 9g54xg97m8b 5 1 these these DET 9g54xg97m8b 5 2 targets target NOUN 9g54xg97m8b 5 3 show show VERB 9g54xg97m8b 5 4 differences difference NOUN 9g54xg97m8b 5 5 in in ADP 9g54xg97m8b 5 6 expression expression NOUN 9g54xg97m8b 5 7 based base VERB 9g54xg97m8b 5 8 on on ADP 9g54xg97m8b 5 9 tissues tissue NOUN 9g54xg97m8b 5 10 affected affect VERB 9g54xg97m8b 5 11 , , PUNCT 9g54xg97m8b 5 12 flow flow NOUN 9g54xg97m8b 5 13 conditions condition NOUN 9g54xg97m8b 5 14 , , PUNCT 9g54xg97m8b 5 15 oxygen oxygen NOUN 9g54xg97m8b 5 16 content content NOUN 9g54xg97m8b 5 17 , , PUNCT 9g54xg97m8b 5 18 and and CCONJ 9g54xg97m8b 5 19 mir mir PROPN 9g54xg97m8b 5 20 release release NOUN 9g54xg97m8b 5 21 mechanisms mechanism NOUN 9g54xg97m8b 5 22 . . PUNCT 9g54xg97m8b 6 1 mir08 mir08 PROPN 9g54xg97m8b 6 2 appears appear VERB 9g54xg97m8b 6 3 to to PART 9g54xg97m8b 6 4 rule rule VERB 9g54xg97m8b 6 5 in in ADP 9g54xg97m8b 6 6 cardiac cardiac ADJ 9g54xg97m8b 6 7 pathology pathology NOUN 9g54xg97m8b 6 8 , , PUNCT 9g54xg97m8b 6 9 mir-1 mir-1 PRON 9g54xg97m8b 6 10 serves serve VERB 9g54xg97m8b 6 11 to to PART 9g54xg97m8b 6 12 discriminate discriminate VERB 9g54xg97m8b 6 13 between between ADP 9g54xg97m8b 6 14 stemi stemi PROPN 9g54xg97m8b 6 15 and and CCONJ 9g54xg97m8b 6 16 cad cad NOUN 9g54xg97m8b 6 17 as as ADV 9g54xg97m8b 6 18 well well ADV 9g54xg97m8b 6 19 as as ADP 9g54xg97m8b 6 20 between between ADP 9g54xg97m8b 6 21 stemi stemi NOUN 9g54xg97m8b 6 22 and and CCONJ 9g54xg97m8b 6 23 control control NOUN 9g54xg97m8b 6 24 , , PUNCT 9g54xg97m8b 6 25 and and CCONJ 9g54xg97m8b 6 26 mir-499 mir-499 PROPN 9g54xg97m8b 6 27 differentiates differentiate NOUN 9g54xg97m8b 6 28 between between ADP 9g54xg97m8b 6 29 cardiomyocyte cardiomyocyte NOUN 9g54xg97m8b 6 30 and and CCONJ 9g54xg97m8b 6 31 endothelial endothelial ADJ 9g54xg97m8b 6 32 cell cell NOUN 9g54xg97m8b 6 33 disruptions disruption NOUN 9g54xg97m8b 6 34 . . PUNCT 9g54xg97m8b 7 1 herein herein ADV 9g54xg97m8b 7 2 a a DET 9g54xg97m8b 7 3 procedure procedure NOUN 9g54xg97m8b 7 4 to to PART 9g54xg97m8b 7 5 lyse lyse VERB 9g54xg97m8b 7 6 extracellular extracellular ADJ 9g54xg97m8b 7 7 vesicles vesicle NOUN 9g54xg97m8b 7 8 with with ADP 9g54xg97m8b 7 9 minimal minimal ADJ 9g54xg97m8b 7 10 processing processing NOUN 9g54xg97m8b 7 11 time time NOUN 9g54xg97m8b 7 12 and and CCONJ 9g54xg97m8b 7 13 no no DET 9g54xg97m8b 7 14 additional additional ADJ 9g54xg97m8b 7 15 buffers buffer NOUN 9g54xg97m8b 7 16 confounding confound VERB 9g54xg97m8b 7 17 mir mir X 9g54xg97m8b 7 18 quantification.expanding quantification.expande VERB 9g54xg97m8b 7 19 the the DET 9g54xg97m8b 7 20 pool pool NOUN 9g54xg97m8b 7 21 of of ADP 9g54xg97m8b 7 22 clinical clinical ADJ 9g54xg97m8b 7 23 samples sample NOUN 9g54xg97m8b 7 24 to to ADP 9g54xg97m8b 7 25 multiplexed multiplexed ADJ 9g54xg97m8b 7 26 sensors sensor NOUN 9g54xg97m8b 7 27 measuring measure VERB 9g54xg97m8b 7 28 these these DET 9g54xg97m8b 7 29 mirs mir NOUN 9g54xg97m8b 7 30 in in ADP 9g54xg97m8b 7 31 combination combination NOUN 9g54xg97m8b 7 32 could could AUX 9g54xg97m8b 7 33 provide provide VERB 9g54xg97m8b 7 34 clinically clinically ADV 9g54xg97m8b 7 35 relevant relevant ADJ 9g54xg97m8b 7 36 information information NOUN 9g54xg97m8b 7 37 . . PUNCT 9g54xg97m8b 8 1 as as SCONJ 9g54xg97m8b 8 2 the the DET 9g54xg97m8b 8 3 tissue tissue NOUN 9g54xg97m8b 8 4 culture culture NOUN 9g54xg97m8b 8 5 models model NOUN 9g54xg97m8b 8 6 better well ADV 9g54xg97m8b 8 7 approximate approximate ADJ 9g54xg97m8b 8 8 clinical clinical ADJ 9g54xg97m8b 8 9 samples sample NOUN 9g54xg97m8b 8 10 they they PRON 9g54xg97m8b 8 11 may may AUX 9g54xg97m8b 8 12 branch branch VERB 9g54xg97m8b 8 13 out out ADP 9g54xg97m8b 8 14 beyond beyond ADP 9g54xg97m8b 8 15 mi mi PROPN 9g54xg97m8b 8 16 modeling modeling NOUN 9g54xg97m8b 8 17 and and CCONJ 9g54xg97m8b 8 18 serve serve VERB 9g54xg97m8b 8 19 to to PART 9g54xg97m8b 8 20 model model VERB 9g54xg97m8b 8 21 intersections intersection NOUN 9g54xg97m8b 8 22 between between ADP 9g54xg97m8b 8 23 mi mi PROPN 9g54xg97m8b 8 24 , , PUNCT 9g54xg97m8b 8 25 cad cad NOUN 9g54xg97m8b 8 26 , , PUNCT 9g54xg97m8b 8 27 and and CCONJ 9g54xg97m8b 8 28 other other ADJ 9g54xg97m8b 8 29 cardiac cardiac ADJ 9g54xg97m8b 8 30 pathologies pathology NOUN 9g54xg97m8b 8 31 . . PUNCT 9g54xg97m8b 9 1 employing employ VERB 9g54xg97m8b 9 2 mir mir ADJ 9g54xg97m8b 9 3 quantification quantification NOUN 9g54xg97m8b 9 4 , , PUNCT 9g54xg97m8b 9 5 ev ev INTJ 9g54xg97m8b 9 6 lysis lysis NOUN 9g54xg97m8b 9 7 , , PUNCT 9g54xg97m8b 9 8 and and CCONJ 9g54xg97m8b 9 9 nm nm ADJ 9g54xg97m8b 9 10 - - ADJ 9g54xg97m8b 9 11 sized sized ADJ 9g54xg97m8b 9 12 particle particle NOUN 9g54xg97m8b 9 13 fractionation fractionation NOUN 9g54xg97m8b 9 14 could could AUX 9g54xg97m8b 9 15 open open VERB 9g54xg97m8b 9 16 a a DET 9g54xg97m8b 9 17 series series NOUN 9g54xg97m8b 9 18 of of ADP 9g54xg97m8b 9 19 pathology pathology NOUN 9g54xg97m8b 9 20 indicators indicator NOUN 9g54xg97m8b 9 21 in in ADP 9g54xg97m8b 9 22 a a DET 9g54xg97m8b 9 23 simple simple ADJ 9g54xg97m8b 9 24 point point NOUN 9g54xg97m8b 9 25 - - PUNCT 9g54xg97m8b 9 26 of of ADP 9g54xg97m8b 9 27 - - PUNCT 9g54xg97m8b 9 28 care care NOUN 9g54xg97m8b 9 29 apparatus apparatus NOUN 9g54xg97m8b 9 30 . . PUNCT