id sid tid token lemma pos 8w32r496x4v 1 1 pertactin pertactin PROPN 8w32r496x4v 1 2 is be AUX 8w32r496x4v 1 3 localized localize VERB 8w32r496x4v 1 4 on on ADP 8w32r496x4v 1 5 the the DET 8w32r496x4v 1 6 outer outer ADJ 8w32r496x4v 1 7 membrane membrane NOUN 8w32r496x4v 1 8 of of ADP 8w32r496x4v 1 9 b. b. NOUN 8w32r496x4v 1 10 pertussis pertussis NOUN 8w32r496x4v 1 11 and and CCONJ 8w32r496x4v 1 12 is be AUX 8w32r496x4v 1 13 one one NUM 8w32r496x4v 1 14 of of ADP 8w32r496x4v 1 15 the the DET 8w32r496x4v 1 16 virulence virulence NOUN 8w32r496x4v 1 17 factors factor NOUN 8w32r496x4v 1 18 believed believe VERB 8w32r496x4v 1 19 to to PART 8w32r496x4v 1 20 contribute contribute VERB 8w32r496x4v 1 21 to to ADP 8w32r496x4v 1 22 the the DET 8w32r496x4v 1 23 disease disease NOUN 8w32r496x4v 1 24 state state NOUN 8w32r496x4v 1 25 of of ADP 8w32r496x4v 1 26 whooping whooping ADJ 8w32r496x4v 1 27 cough cough NOUN 8w32r496x4v 1 28 , , PUNCT 8w32r496x4v 1 29 an an DET 8w32r496x4v 1 30 acute acute ADJ 8w32r496x4v 1 31 respiratory respiratory ADJ 8w32r496x4v 1 32 disease disease NOUN 8w32r496x4v 1 33 of of ADP 8w32r496x4v 1 34 children child NOUN 8w32r496x4v 1 35 . . PUNCT 8w32r496x4v 2 1 as as ADP 8w32r496x4v 2 2 the the DET 8w32r496x4v 2 3 precursor precursor PROPN 8w32r496x4v 2 4 protein protein NOUN 8w32r496x4v 2 5 , , PUNCT 8w32r496x4v 2 6 p.93 p.93 PRON 8w32r496x4v 2 7 pertactin pertactin PROPN 8w32r496x4v 2 8 has have AUX 8w32r496x4v 2 9 been be AUX 8w32r496x4v 2 10 identified identify VERB 8w32r496x4v 2 11 as as ADP 8w32r496x4v 2 12 an an DET 8w32r496x4v 2 13 autotransporter autotransporter NOUN 8w32r496x4v 2 14 ( ( PUNCT 8w32r496x4v 2 15 at at ADP 8w32r496x4v 2 16 ) ) PUNCT 8w32r496x4v 2 17 . . PUNCT 8w32r496x4v 3 1 it it PRON 8w32r496x4v 3 2 is be AUX 8w32r496x4v 3 3 translocated translocate VERB 8w32r496x4v 3 4 across across ADP 8w32r496x4v 3 5 the the DET 8w32r496x4v 3 6 inner inner ADJ 8w32r496x4v 3 7 membrane membrane NOUN 8w32r496x4v 3 8 ( ( PUNCT 8w32r496x4v 3 9 i i PRON 8w32r496x4v 3 10 m m VERB 8w32r496x4v 3 11 ) ) PUNCT 8w32r496x4v 3 12 , , PUNCT 8w32r496x4v 3 13 and and CCONJ 8w32r496x4v 3 14 then then ADV 8w32r496x4v 3 15 it it PRON 8w32r496x4v 3 16 is be AUX 8w32r496x4v 3 17 secreted secrete VERB 8w32r496x4v 3 18 across across ADP 8w32r496x4v 3 19 the the DET 8w32r496x4v 3 20 outer outer ADJ 8w32r496x4v 3 21 membrane membrane NOUN 8w32r496x4v 3 22 ( ( PUNCT 8w32r496x4v 3 23 om om NOUN 8w32r496x4v 3 24 ) ) PUNCT 8w32r496x4v 3 25 with with ADP 8w32r496x4v 3 26 its its PRON 8w32r496x4v 3 27 c c ADJ 8w32r496x4v 3 28 - - PUNCT 8w32r496x4v 3 29 terminal terminal NOUN 8w32r496x4v 3 30 porin porin NOUN 8w32r496x4v 3 31 domain domain NOUN 8w32r496x4v 3 32 forming form VERB 8w32r496x4v 3 33 a a DET 8w32r496x4v 3 34 pore pore NOUN 8w32r496x4v 3 35 through through ADP 8w32r496x4v 3 36 which which PRON 8w32r496x4v 3 37 the the DET 8w32r496x4v 3 38 p.69 p.69 NOUN 8w32r496x4v 3 39 passenger passenger NOUN 8w32r496x4v 3 40 domain domain NOUN 8w32r496x4v 3 41 is be AUX 8w32r496x4v 3 42 transported transport VERB 8w32r496x4v 3 43 out out ADP 8w32r496x4v 3 44 of of ADP 8w32r496x4v 3 45 the the DET 8w32r496x4v 3 46 cell cell NOUN 8w32r496x4v 3 47 . . PUNCT 8w32r496x4v 4 1 during during ADP 8w32r496x4v 4 2 this this DET 8w32r496x4v 4 3 secretion secretion NOUN 8w32r496x4v 4 4 process process NOUN 8w32r496x4v 4 5 , , PUNCT 8w32r496x4v 4 6 p.69 p.69 VERB 8w32r496x4v 4 7 pertactin pertactin NOUN 8w32r496x4v 4 8 is be AUX 8w32r496x4v 4 9 cleaved cleave VERB 8w32r496x4v 4 10 from from ADP 8w32r496x4v 4 11 the the DET 8w32r496x4v 4 12 porin porin NOUN 8w32r496x4v 4 13 domain domain NOUN 8w32r496x4v 4 14 by by ADP 8w32r496x4v 4 15 either either CCONJ 8w32r496x4v 4 16 an an DET 8w32r496x4v 4 17 unidentified unidentified ADJ 8w32r496x4v 4 18 om om NOUN 8w32r496x4v 4 19 protease protease NOUN 8w32r496x4v 4 20 , , PUNCT 8w32r496x4v 4 21 or or CCONJ 8w32r496x4v 4 22 an an DET 8w32r496x4v 4 23 autocatalytic autocatalytic ADJ 8w32r496x4v 4 24 mechanism mechanism NOUN 8w32r496x4v 4 25 . . PUNCT 8w32r496x4v 5 1 in in ADP 8w32r496x4v 5 2 this this DET 8w32r496x4v 5 3 study study NOUN 8w32r496x4v 5 4 , , PUNCT 8w32r496x4v 5 5 we we PRON 8w32r496x4v 5 6 investigated investigate VERB 8w32r496x4v 5 7 possible possible ADJ 8w32r496x4v 5 8 candidates candidate NOUN 8w32r496x4v 5 9 of of ADP 8w32r496x4v 5 10 the the DET 8w32r496x4v 5 11 cleavage cleavage NOUN 8w32r496x4v 5 12 site site NOUN 8w32r496x4v 5 13 and and CCONJ 8w32r496x4v 5 14 we we PRON 8w32r496x4v 5 15 found find VERB 8w32r496x4v 5 16 that that SCONJ 8w32r496x4v 5 17 when when SCONJ 8w32r496x4v 5 18 s602 s602 PROPN 8w32r496x4v 5 19 was be AUX 8w32r496x4v 5 20 mutated mutate VERB 8w32r496x4v 5 21 to to ADP 8w32r496x4v 5 22 alanine alanine NOUN 8w32r496x4v 5 23 , , PUNCT 8w32r496x4v 5 24 the the DET 8w32r496x4v 5 25 proteolysis proteolysis NOUN 8w32r496x4v 5 26 occuring occur VERB 8w32r496x4v 5 27 at at ADP 8w32r496x4v 5 28 the the DET 8w32r496x4v 5 29 om om PROPN 8w32r496x4v 5 30 was be AUX 8w32r496x4v 5 31 obviously obviously ADV 8w32r496x4v 5 32 impaired impair VERB 8w32r496x4v 5 33 . . PUNCT 8w32r496x4v 6 1 besides besides SCONJ 8w32r496x4v 6 2 we we PRON 8w32r496x4v 6 3 also also ADV 8w32r496x4v 6 4 found find VERB 8w32r496x4v 6 5 different different ADJ 8w32r496x4v 6 6 effects effect NOUN 8w32r496x4v 6 7 of of ADP 8w32r496x4v 6 8 this this DET 8w32r496x4v 6 9 mutation mutation NOUN 8w32r496x4v 6 10 to to ADP 8w32r496x4v 6 11 the the DET 8w32r496x4v 6 12 proteolytic proteolytic ADJ 8w32r496x4v 6 13 process process NOUN 8w32r496x4v 6 14 occuring occur VERB 8w32r496x4v 6 15 at at ADP 8w32r496x4v 6 16 the the DET 8w32r496x4v 6 17 om om NOUN 8w32r496x4v 6 18 in in ADP 8w32r496x4v 6 19 different different ADJ 8w32r496x4v 6 20 cell cell NOUN 8w32r496x4v 6 21 strains strain NOUN 8w32r496x4v 6 22 of of ADP 8w32r496x4v 6 23 e. e. PROPN 8w32r496x4v 6 24 coli coli NOUN 8w32r496x4v 6 25 cells cell NOUN 8w32r496x4v 6 26 , , PUNCT 8w32r496x4v 6 27 which which PRON 8w32r496x4v 6 28 suggested suggest VERB 8w32r496x4v 6 29 it it PRON 8w32r496x4v 6 30 was be AUX 8w32r496x4v 6 31 unlikely unlikely ADJ 8w32r496x4v 6 32 that that SCONJ 8w32r496x4v 6 33 this this DET 8w32r496x4v 6 34 proteolysis proteolysis NOUN 8w32r496x4v 6 35 occuring occur VERB 8w32r496x4v 6 36 at at ADP 8w32r496x4v 6 37 the the DET 8w32r496x4v 6 38 om om PROPN 8w32r496x4v 6 39 was be AUX 8w32r496x4v 6 40 autocatalytic autocatalytic ADJ 8w32r496x4v 6 41 . . PUNCT