id	sid	tid	token	lemma	pos
8s45q813p6k	1	1	in	in	ADP
8s45q813p6k	1	2	the	the	DET
8s45q813p6k	1	3	era	era	NOUN
8s45q813p6k	1	4	of	of	ADP
8s45q813p6k	1	5	big	big	ADJ
8s45q813p6k	1	6	data	datum	NOUN
8s45q813p6k	1	7	,	,	PUNCT
8s45q813p6k	1	8	there	there	PRON
8s45q813p6k	1	9	is	be	VERB
8s45q813p6k	1	10	an	an	DET
8s45q813p6k	1	11	ever	ever	ADV
8s45q813p6k	1	12	-	-	PUNCT
8s45q813p6k	1	13	increasing	increase	VERB
8s45q813p6k	1	14	breadth	breadth	NOUN
8s45q813p6k	1	15	of	of	ADP
8s45q813p6k	1	16	both	both	DET
8s45q813p6k	1	17	open	open	ADJ
8s45q813p6k	1	18	-	-	PUNCT
8s45q813p6k	1	19	source	source	NOUN
8s45q813p6k	1	20	data	datum	NOUN
8s45q813p6k	1	21	and	and	CCONJ
8s45q813p6k	1	22	advanced	advanced	ADJ
8s45q813p6k	1	23	quantitative	quantitative	ADJ
8s45q813p6k	1	24	tools	tool	NOUN
8s45q813p6k	1	25	available	available	ADJ
8s45q813p6k	1	26	for	for	ADP
8s45q813p6k	1	27	studying	study	VERB
8s45q813p6k	1	28	biology	biology	NOUN
8s45q813p6k	1	29	;	;	PUNCT
8s45q813p6k	1	30	from	from	ADP
8s45q813p6k	1	31	rna	rna	NOUN
8s45q813p6k	1	32	-	-	PUNCT
8s45q813p6k	1	33	sequencing	sequencing	NOUN
8s45q813p6k	1	34	to	to	ADP
8s45q813p6k	1	35	high	high	ADJ
8s45q813p6k	1	36	-	-	PUNCT
8s45q813p6k	1	37	throughput	throughput	NOUN
8s45q813p6k	1	38	screening	screening	NOUN
8s45q813p6k	1	39	(	(	PUNCT
8s45q813p6k	1	40	hts	ht	NOUN
8s45q813p6k	1	41	)	)	PUNCT
8s45q813p6k	1	42	,	,	PUNCT
8s45q813p6k	1	43	advanced	advanced	ADJ
8s45q813p6k	1	44	technologies	technology	NOUN
8s45q813p6k	1	45	have	have	AUX
8s45q813p6k	1	46	changed	change	VERB
8s45q813p6k	1	47	the	the	DET
8s45q813p6k	1	48	landscape	landscape	NOUN
8s45q813p6k	1	49	of	of	ADP
8s45q813p6k	1	50	biological	biological	ADJ
8s45q813p6k	1	51	research	research	NOUN
8s45q813p6k	1	52	and	and	CCONJ
8s45q813p6k	1	53	medicine	medicine	NOUN
8s45q813p6k	1	54	.	.	PUNCT
8s45q813p6k	2	1	however	however	ADV
8s45q813p6k	2	2	,	,	PUNCT
8s45q813p6k	2	3	there	there	PRON
8s45q813p6k	2	4	are	be	VERB
8s45q813p6k	2	5	still	still	ADV
8s45q813p6k	2	6	many	many	ADJ
8s45q813p6k	2	7	challenges	challenge	NOUN
8s45q813p6k	2	8	associated	associate	VERB
8s45q813p6k	2	9	with	with	ADP
8s45q813p6k	2	10	fully	fully	ADV
8s45q813p6k	2	11	harnessing	harness	VERB
8s45q813p6k	2	12	the	the	DET
8s45q813p6k	2	13	available	available	ADJ
8s45q813p6k	2	14	resources	resource	NOUN
8s45q813p6k	2	15	for	for	ADP
8s45q813p6k	2	16	particular	particular	ADJ
8s45q813p6k	2	17	applications	application	NOUN
8s45q813p6k	2	18	;	;	PUNCT
8s45q813p6k	2	19	specifically	specifically	ADV
8s45q813p6k	2	20	,	,	PUNCT
8s45q813p6k	2	21	comparatively	comparatively	ADV
8s45q813p6k	2	22	little	little	ADJ
8s45q813p6k	2	23	has	have	AUX
8s45q813p6k	2	24	been	be	AUX
8s45q813p6k	2	25	done	do	VERB
8s45q813p6k	2	26	to	to	PART
8s45q813p6k	2	27	integrate	integrate	VERB
8s45q813p6k	2	28	data	datum	NOUN
8s45q813p6k	2	29	and	and	CCONJ
8s45q813p6k	2	30	disparate	disparate	ADJ
8s45q813p6k	2	31	tools	tool	NOUN
8s45q813p6k	2	32	for	for	ADP
8s45q813p6k	2	33	systems	system	NOUN
8s45q813p6k	2	34	-	-	PUNCT
8s45q813p6k	2	35	level	level	NOUN
8s45q813p6k	2	36	solutions	solution	NOUN
8s45q813p6k	2	37	.	.	PUNCT
8s45q813p6k	3	1	the	the	DET
8s45q813p6k	3	2	work	work	NOUN
8s45q813p6k	3	3	herein	herein	ADV
8s45q813p6k	3	4	describes	describe	VERB
8s45q813p6k	3	5	multiple	multiple	ADJ
8s45q813p6k	3	6	case	case	NOUN
8s45q813p6k	3	7	studies	study	NOUN
8s45q813p6k	3	8	where	where	SCONJ
8s45q813p6k	3	9	integrative	integrative	ADJ
8s45q813p6k	3	10	approaches	approach	NOUN
8s45q813p6k	3	11	were	be	AUX
8s45q813p6k	3	12	applied	apply	VERB
8s45q813p6k	3	13	to	to	PART
8s45q813p6k	3	14	synthesize	synthesize	VERB
8s45q813p6k	3	15	and	and	CCONJ
8s45q813p6k	3	16	build	build	VERB
8s45q813p6k	3	17	on	on	ADP
8s45q813p6k	3	18	the	the	DET
8s45q813p6k	3	19	wealth	wealth	NOUN
8s45q813p6k	3	20	of	of	ADP
8s45q813p6k	3	21	resources	resource	NOUN
8s45q813p6k	3	22	available	available	ADJ
8s45q813p6k	3	23	to	to	PART
8s45q813p6k	3	24	advance	advance	VERB
8s45q813p6k	3	25	biotechnology	biotechnology	NOUN
8s45q813p6k	3	26	,	,	PUNCT
8s45q813p6k	3	27	preclinical	preclinical	ADJ
8s45q813p6k	3	28	medicine	medicine	NOUN
8s45q813p6k	3	29	,	,	PUNCT
8s45q813p6k	3	30	and	and	CCONJ
8s45q813p6k	3	31	more	more	ADV
8s45q813p6k	3	32	fundamentally	fundamentally	ADV
8s45q813p6k	3	33	in	in	ADP
8s45q813p6k	3	34	developmental	developmental	ADJ
8s45q813p6k	3	35	biology	biology	NOUN
8s45q813p6k	3	36	.	.	PUNCT
8s45q813p6k	4	1	this	this	DET
8s45q813p6k	4	2	thesis	thesis	NOUN
8s45q813p6k	4	3	describes	describe	VERB
8s45q813p6k	4	4	several	several	ADJ
8s45q813p6k	4	5	milestone	milestone	NOUN
8s45q813p6k	4	6	applications	application	NOUN
8s45q813p6k	4	7	that	that	PRON
8s45q813p6k	4	8	advance	advance	VERB
8s45q813p6k	4	9	the	the	DET
8s45q813p6k	4	10	state	state	NOUN
8s45q813p6k	4	11	-	-	PUNCT
8s45q813p6k	4	12	of	of	ADP
8s45q813p6k	4	13	-	-	PUNCT
8s45q813p6k	4	14	the	the	DET
8s45q813p6k	4	15	art	art	NOUN
8s45q813p6k	4	16	in	in	ADP
8s45q813p6k	4	17	each	each	DET
8s45q813p6k	4	18	field	field	NOUN
8s45q813p6k	4	19	:	:	PUNCT
8s45q813p6k	4	20	the	the	DET
8s45q813p6k	4	21	generation	generation	NOUN
8s45q813p6k	4	22	of	of	ADP
8s45q813p6k	4	23	the	the	DET
8s45q813p6k	4	24	first	first	ADJ
8s45q813p6k	4	25	chemically	chemically	ADV
8s45q813p6k	4	26	defined	define	VERB
8s45q813p6k	4	27	cell	cell	NOUN
8s45q813p6k	4	28	culture	culture	NOUN
8s45q813p6k	4	29	medium	medium	NOUN
8s45q813p6k	4	30	enabling	enable	VERB
8s45q813p6k	4	31	long	long	ADJ
8s45q813p6k	4	32	term	term	NOUN
8s45q813p6k	4	33	culture	culture	NOUN
8s45q813p6k	4	34	of	of	ADP
8s45q813p6k	4	35	a	a	DET
8s45q813p6k	4	36	drosophila	drosophila	NOUN
8s45q813p6k	4	37	cell	cell	NOUN
8s45q813p6k	4	38	lines	line	NOUN
8s45q813p6k	4	39	(	(	PUNCT
8s45q813p6k	4	40	chapter	chapter	NOUN
8s45q813p6k	4	41	2	2	NUM
8s45q813p6k	4	42	)	)	PUNCT
8s45q813p6k	4	43	;	;	PUNCT
8s45q813p6k	4	44	building	build	VERB
8s45q813p6k	4	45	on	on	ADP
8s45q813p6k	4	46	these	these	DET
8s45q813p6k	4	47	results	result	NOUN
8s45q813p6k	4	48	led	lead	VERB
8s45q813p6k	4	49	to	to	ADP
8s45q813p6k	4	50	unexpected	unexpected	ADJ
8s45q813p6k	4	51	discoveries	discovery	NOUN
8s45q813p6k	4	52	in	in	ADP
8s45q813p6k	4	53	the	the	DET
8s45q813p6k	4	54	field	field	NOUN
8s45q813p6k	4	55	of	of	ADP
8s45q813p6k	4	56	developmental	developmental	ADJ
8s45q813p6k	4	57	biology	biology	NOUN
8s45q813p6k	4	58	with	with	ADP
8s45q813p6k	4	59	the	the	DET
8s45q813p6k	4	60	discovery	discovery	NOUN
8s45q813p6k	4	61	of	of	ADP
8s45q813p6k	4	62	novel	novel	ADJ
8s45q813p6k	4	63	spatiotemporal	spatiotemporal	ADJ
8s45q813p6k	4	64	patterning	patterning	NOUN
8s45q813p6k	4	65	of	of	ADP
8s45q813p6k	4	66	polyamines	polyamine	NOUN
8s45q813p6k	4	67	during	during	ADP
8s45q813p6k	4	68	organogenesis	organogenesis	NOUN
8s45q813p6k	4	69	(	(	PUNCT
8s45q813p6k	4	70	chapter	chapter	NOUN
8s45q813p6k	4	71	3	3	NUM
8s45q813p6k	4	72	)	)	PUNCT
8s45q813p6k	4	73	;	;	PUNCT
8s45q813p6k	4	74	the	the	DET
8s45q813p6k	4	75	optimization	optimization	NOUN
8s45q813p6k	4	76	and	and	CCONJ
8s45q813p6k	4	77	application	application	NOUN
8s45q813p6k	4	78	of	of	ADP
8s45q813p6k	4	79	an	an	DET
8s45q813p6k	4	80	in	in	ADP
8s45q813p6k	4	81	vivo	vivo	ADJ
8s45q813p6k	4	82	tumor	tumor	NOUN
8s45q813p6k	4	83	screening	screening	NOUN
8s45q813p6k	4	84	approach	approach	NOUN
8s45q813p6k	4	85	to	to	PART
8s45q813p6k	4	86	efficiently	efficiently	ADV
8s45q813p6k	4	87	identify	identify	VERB
8s45q813p6k	4	88	novel	novel	ADJ
8s45q813p6k	4	89	functional	functional	ADJ
8s45q813p6k	4	90	targets	target	NOUN
8s45q813p6k	4	91	during	during	ADP
8s45q813p6k	4	92	secondary	secondary	ADJ
8s45q813p6k	4	93	metastatic	metastatic	ADJ
8s45q813p6k	4	94	outgrowth	outgrowth	NOUN
8s45q813p6k	4	95	in	in	ADP
8s45q813p6k	4	96	tumors	tumor	NOUN
8s45q813p6k	4	97	(	(	PUNCT
8s45q813p6k	4	98	chapter	chapter	NOUN
8s45q813p6k	4	99	4	4	NUM
8s45q813p6k	4	100	)	)	PUNCT
8s45q813p6k	4	101	;	;	PUNCT
8s45q813p6k	4	102	and	and	CCONJ
8s45q813p6k	4	103	through	through	ADP
8s45q813p6k	4	104	a	a	DET
8s45q813p6k	4	105	close	close	ADJ
8s45q813p6k	4	106	,	,	PUNCT
8s45q813p6k	4	107	multidisciplinary	multidisciplinary	ADJ
8s45q813p6k	4	108	collaboration	collaboration	NOUN
8s45q813p6k	4	109	,	,	PUNCT
8s45q813p6k	4	110	the	the	DET
8s45q813p6k	4	111	characterization	characterization	NOUN
8s45q813p6k	4	112	of	of	ADP
8s45q813p6k	4	113	novel	novel	NOUN
8s45q813p6k	4	114	compounds	compound	NOUN
8s45q813p6k	4	115	through	through	ADP
8s45q813p6k	4	116	both	both	CCONJ
8s45q813p6k	4	117	cytotoxicity	cytotoxicity	NOUN
8s45q813p6k	4	118	and	and	CCONJ
8s45q813p6k	4	119	mechanism	mechanism	NOUN
8s45q813p6k	4	120	of	of	ADP
8s45q813p6k	4	121	action	action	NOUN
8s45q813p6k	4	122	studies	study	NOUN
8s45q813p6k	4	123	,	,	PUNCT
8s45q813p6k	4	124	along	along	ADP
8s45q813p6k	4	125	with	with	ADP
8s45q813p6k	4	126	the	the	DET
8s45q813p6k	4	127	preliminary	preliminary	ADJ
8s45q813p6k	4	128	creation	creation	NOUN
8s45q813p6k	4	129	of	of	ADP
8s45q813p6k	4	130	an	an	DET
8s45q813p6k	4	131	ultra	ultra	ADJ
8s45q813p6k	4	132	-	-	ADJ
8s45q813p6k	4	133	high	high	ADJ
8s45q813p6k	4	134	-	-	PUNCT
8s45q813p6k	4	135	content	content	NOUN
8s45q813p6k	4	136	screening	screen	VERB
8s45q813p6k	4	137	platform	platform	NOUN
8s45q813p6k	4	138	for	for	ADP
8s45q813p6k	4	139	structure	structure	NOUN
8s45q813p6k	4	140	-	-	PUNCT
8s45q813p6k	4	141	activity	activity	NOUN
8s45q813p6k	4	142	analysis	analysis	NOUN
8s45q813p6k	4	143	of	of	ADP
8s45q813p6k	4	144	compound	compound	NOUN
8s45q813p6k	4	145	libraries	library	NOUN
8s45q813p6k	4	146	(	(	PUNCT
8s45q813p6k	4	147	chapter	chapter	NOUN
8s45q813p6k	4	148	5	5	NUM
8s45q813p6k	4	149	)	)	PUNCT
8s45q813p6k	4	150	.	.	PUNCT
8s45q813p6k	5	1	for	for	ADP
8s45q813p6k	5	2	each	each	DET
8s45q813p6k	5	3	application	application	NOUN
8s45q813p6k	5	4	,	,	PUNCT
8s45q813p6k	5	5	several	several	ADJ
8s45q813p6k	5	6	avenues	avenue	NOUN
8s45q813p6k	5	7	are	be	AUX
8s45q813p6k	5	8	available	available	ADJ
8s45q813p6k	5	9	to	to	PART
8s45q813p6k	5	10	further	far	ADV
8s45q813p6k	5	11	progress	progress	VERB
8s45q813p6k	5	12	the	the	DET
8s45q813p6k	5	13	technology	technology	NOUN
8s45q813p6k	5	14	,	,	PUNCT
8s45q813p6k	5	15	which	which	PRON
8s45q813p6k	5	16	is	be	AUX
8s45q813p6k	5	17	discussed	discuss	VERB
8s45q813p6k	5	18	in	in	ADP
8s45q813p6k	5	19	the	the	DET
8s45q813p6k	5	20	concluding	conclude	VERB
8s45q813p6k	5	21	chapter	chapter	NOUN
8s45q813p6k	5	22	(	(	PUNCT
8s45q813p6k	5	23	chapter	chapter	NOUN
8s45q813p6k	5	24	6	6	NUM
8s45q813p6k	5	25	)	)	PUNCT
8s45q813p6k	5	26	.	.	PUNCT