id	sid	tid	token	lemma	pos
8s45q813n68	1	1	single	single	ADJ
8s45q813n68	1	2	-	-	PUNCT
8s45q813n68	1	3	molecule	molecule	NOUN
8s45q813n68	1	4	studies	study	NOUN
8s45q813n68	1	5	with	with	ADP
8s45q813n68	1	6	optical	optical	ADJ
8s45q813n68	1	7	techniques	technique	NOUN
8s45q813n68	1	8	have	have	AUX
8s45q813n68	1	9	become	become	VERB
8s45q813n68	1	10	instrumental	instrumental	ADJ
8s45q813n68	1	11	in	in	ADP
8s45q813n68	1	12	shedding	shed	VERB
8s45q813n68	1	13	light	light	NOUN
8s45q813n68	1	14	upon	upon	SCONJ
8s45q813n68	1	15	the	the	DET
8s45q813n68	1	16	heterogeneities	heterogeneity	NOUN
8s45q813n68	1	17	in	in	ADP
8s45q813n68	1	18	molecular	molecular	ADJ
8s45q813n68	1	19	property	property	NOUN
8s45q813n68	1	20	distributions	distribution	NOUN
8s45q813n68	1	21	,	,	PUNCT
8s45q813n68	1	22	which	which	PRON
8s45q813n68	1	23	are	be	AUX
8s45q813n68	1	24	averaged	average	VERB
8s45q813n68	1	25	out	out	ADP
8s45q813n68	1	26	in	in	ADP
8s45q813n68	1	27	ensemble	ensemble	ADJ
8s45q813n68	1	28	measurements	measurement	NOUN
8s45q813n68	1	29	.	.	PUNCT
8s45q813n68	2	1	gaining	gain	VERB
8s45q813n68	2	2	insights	insight	NOUN
8s45q813n68	2	3	into	into	ADP
8s45q813n68	2	4	the	the	DET
8s45q813n68	2	5	nature	nature	NOUN
8s45q813n68	2	6	and	and	CCONJ
8s45q813n68	2	7	magnitude	magnitude	NOUN
8s45q813n68	2	8	of	of	ADP
8s45q813n68	2	9	such	such	ADJ
8s45q813n68	2	10	heterogeneities	heterogeneity	NOUN
8s45q813n68	2	11	in	in	ADP
8s45q813n68	2	12	molecular	molecular	ADJ
8s45q813n68	2	13	systems	system	NOUN
8s45q813n68	2	14	,	,	PUNCT
8s45q813n68	2	15	particularly	particularly	ADV
8s45q813n68	2	16	when	when	SCONJ
8s45q813n68	2	17	they	they	PRON
8s45q813n68	2	18	are	be	AUX
8s45q813n68	2	19	subject	subject	ADJ
8s45q813n68	2	20	to	to	ADP
8s45q813n68	2	21	anisotropic	anisotropic	NOUN
8s45q813n68	2	22	chemical	chemical	NOUN
8s45q813n68	2	23	,	,	PUNCT
8s45q813n68	2	24	optical	optical	ADJ
8s45q813n68	2	25	,	,	PUNCT
8s45q813n68	2	26	electrical	electrical	ADJ
8s45q813n68	2	27	,	,	PUNCT
8s45q813n68	2	28	or	or	CCONJ
8s45q813n68	2	29	other	other	ADJ
8s45q813n68	2	30	perturbations	perturbation	NOUN
8s45q813n68	2	31	,	,	PUNCT
8s45q813n68	2	32	has	have	VERB
8s45q813n68	2	33	important	important	ADJ
8s45q813n68	2	34	implications	implication	NOUN
8s45q813n68	2	35	in	in	ADP
8s45q813n68	2	36	the	the	DET
8s45q813n68	2	37	design	design	NOUN
8s45q813n68	2	38	of	of	ADP
8s45q813n68	2	39	targeted	target	VERB
8s45q813n68	2	40	detection	detection	NOUN
8s45q813n68	2	41	schemes	scheme	NOUN
8s45q813n68	2	42	.	.	PUNCT
8s45q813n68	3	1	strategies	strategy	NOUN
8s45q813n68	3	2	that	that	PRON
8s45q813n68	3	3	enable	enable	VERB
8s45q813n68	3	4	detection	detection	NOUN
8s45q813n68	3	5	and	and	CCONJ
8s45q813n68	3	6	manipulation	manipulation	NOUN
8s45q813n68	3	7	of	of	ADP
8s45q813n68	3	8	subpopulations	subpopulation	NOUN
8s45q813n68	3	9	of	of	ADP
8s45q813n68	3	10	molecules	molecule	NOUN
8s45q813n68	3	11	have	have	VERB
8s45q813n68	3	12	the	the	DET
8s45q813n68	3	13	potential	potential	NOUN
8s45q813n68	3	14	to	to	PART
8s45q813n68	3	15	contribute	contribute	VERB
8s45q813n68	3	16	in	in	ADP
8s45q813n68	3	17	transformational	transformational	ADJ
8s45q813n68	3	18	ways	way	NOUN
8s45q813n68	3	19	to	to	ADP
8s45q813n68	3	20	lab	lab	NOUN
8s45q813n68	3	21	-	-	PUNCT
8s45q813n68	3	22	on	on	ADP
8s45q813n68	3	23	-	-	PUNCT
8s45q813n68	3	24	a	a	DET
8s45q813n68	3	25	-	-	PUNCT
8s45q813n68	3	26	chip	chip	NOUN
8s45q813n68	3	27	(	(	PUNCT
8s45q813n68	3	28	loc	loc	PROPN
8s45q813n68	3	29	)	)	PUNCT
8s45q813n68	3	30	analytical	analytical	ADJ
8s45q813n68	3	31	systems	system	NOUN
8s45q813n68	3	32	and	and	CCONJ
8s45q813n68	3	33	point	point	NOUN
8s45q813n68	3	34	-	-	PUNCT
8s45q813n68	3	35	of	of	ADP
8s45q813n68	3	36	-	-	PUNCT
8s45q813n68	3	37	care	care	NOUN
8s45q813n68	3	38	(	(	PUNCT
8s45q813n68	3	39	poc	poc	X
8s45q813n68	3	40	)	)	PUNCT
8s45q813n68	3	41	diagnostic	diagnostic	ADJ
8s45q813n68	3	42	devices.the	devices.the	DET
8s45q813n68	3	43	work	work	NOUN
8s45q813n68	3	44	in	in	ADP
8s45q813n68	3	45	this	this	DET
8s45q813n68	3	46	dissertation	dissertation	NOUN
8s45q813n68	3	47	aims	aim	VERB
8s45q813n68	3	48	to	to	PART
8s45q813n68	3	49	provide	provide	VERB
8s45q813n68	3	50	a	a	DET
8s45q813n68	3	51	novel	novel	ADJ
8s45q813n68	3	52	approach	approach	NOUN
8s45q813n68	3	53	for	for	ADP
8s45q813n68	3	54	the	the	DET
8s45q813n68	3	55	electrochemical	electrochemical	ADJ
8s45q813n68	3	56	manipulation	manipulation	NOUN
8s45q813n68	3	57	of	of	ADP
8s45q813n68	3	58	redox	redox	ADJ
8s45q813n68	3	59	-	-	PUNCT
8s45q813n68	3	60	active	active	ADJ
8s45q813n68	3	61	fluorophores	fluorophore	NOUN
8s45q813n68	3	62	coupled	couple	VERB
8s45q813n68	3	63	with	with	ADP
8s45q813n68	3	64	spectroscopic	spectroscopic	ADJ
8s45q813n68	3	65	measurements	measurement	NOUN
8s45q813n68	3	66	.	.	PUNCT
8s45q813n68	4	1	the	the	DET
8s45q813n68	4	2	design	design	NOUN
8s45q813n68	4	3	,	,	PUNCT
8s45q813n68	4	4	construction	construction	NOUN
8s45q813n68	4	5	,	,	PUNCT
8s45q813n68	4	6	and	and	CCONJ
8s45q813n68	4	7	utilization	utilization	NOUN
8s45q813n68	4	8	of	of	ADP
8s45q813n68	4	9	a	a	DET
8s45q813n68	4	10	fluorescence	fluorescence	ADJ
8s45q813n68	4	11	correlation	correlation	NOUN
8s45q813n68	4	12	spectroscopy	spectroscopy	NOUN
8s45q813n68	4	13	(	(	PUNCT
8s45q813n68	4	14	fcs	fcs	ADJ
8s45q813n68	4	15	)	)	PUNCT
8s45q813n68	4	16	optical	optical	ADJ
8s45q813n68	4	17	system	system	NOUN
8s45q813n68	4	18	for	for	ADP
8s45q813n68	4	19	the	the	DET
8s45q813n68	4	20	measurement	measurement	NOUN
8s45q813n68	4	21	of	of	ADP
8s45q813n68	4	22	freely	freely	ADV
8s45q813n68	4	23	diffusing	diffuse	VERB
8s45q813n68	4	24	single	single	ADJ
8s45q813n68	4	25	-	-	PUNCT
8s45q813n68	4	26	molecules	molecule	NOUN
8s45q813n68	4	27	form	form	VERB
8s45q813n68	4	28	the	the	DET
8s45q813n68	4	29	basis	basis	NOUN
8s45q813n68	4	30	for	for	ADP
8s45q813n68	4	31	more	more	ADV
8s45q813n68	4	32	advanced	advanced	ADJ
8s45q813n68	4	33	studies	study	NOUN
8s45q813n68	4	34	.	.	PUNCT
8s45q813n68	5	1	piezoelectric	piezoelectric	ADJ
8s45q813n68	5	2	stages	stage	NOUN
8s45q813n68	5	3	for	for	ADP
8s45q813n68	5	4	nanometer	nanometer	NOUN
8s45q813n68	5	5	spatial	spatial	ADJ
8s45q813n68	5	6	resolution	resolution	NOUN
8s45q813n68	5	7	and	and	CCONJ
8s45q813n68	5	8	advanced	advanced	ADJ
8s45q813n68	5	9	acquisition	acquisition	NOUN
8s45q813n68	5	10	hardware	hardware	NOUN
8s45q813n68	5	11	for	for	ADP
8s45q813n68	5	12	sub	sub	ADJ
8s45q813n68	5	13	-	-	ADJ
8s45q813n68	5	14	nanosecond	nanosecond	ADJ
8s45q813n68	5	15	temporal	temporal	ADJ
8s45q813n68	5	16	resolution	resolution	NOUN
8s45q813n68	5	17	are	be	AUX
8s45q813n68	5	18	implemented	implement	VERB
8s45q813n68	5	19	.	.	PUNCT
8s45q813n68	6	1	the	the	DET
8s45q813n68	6	2	fabrication	fabrication	NOUN
8s45q813n68	6	3	of	of	ADP
8s45q813n68	6	4	au	au	ADV
8s45q813n68	6	5	-	-	ADJ
8s45q813n68	6	6	clad	clothe	VERB
8s45q813n68	6	7	zero	zero	NUM
8s45q813n68	6	8	-	-	PUNCT
8s45q813n68	6	9	mode	mode	NOUN
8s45q813n68	6	10	waveguide	waveguide	NOUN
8s45q813n68	6	11	(	(	PUNCT
8s45q813n68	6	12	zmw	zmw	NOUN
8s45q813n68	6	13	)	)	PUNCT
8s45q813n68	6	14	arrays	array	NOUN
8s45q813n68	6	15	by	by	ADP
8s45q813n68	6	16	focused	focused	ADJ
8s45q813n68	6	17	ion	ion	NOUN
8s45q813n68	6	18	beam	beam	NOUN
8s45q813n68	6	19	(	(	PUNCT
8s45q813n68	6	20	fib	fib	NOUN
8s45q813n68	6	21	)	)	PUNCT
8s45q813n68	6	22	milling	milling	NOUN
8s45q813n68	6	23	is	be	AUX
8s45q813n68	6	24	described	describe	VERB
8s45q813n68	6	25	.	.	PUNCT
8s45q813n68	7	1	simulations	simulation	NOUN
8s45q813n68	7	2	of	of	ADP
8s45q813n68	7	3	the	the	DET
8s45q813n68	7	4	decay	decay	NOUN
8s45q813n68	7	5	of	of	ADP
8s45q813n68	7	6	the	the	DET
8s45q813n68	7	7	optical	optical	ADJ
8s45q813n68	7	8	field	field	NOUN
8s45q813n68	7	9	within	within	ADP
8s45q813n68	7	10	zmws	zmws	NOUN
8s45q813n68	7	11	support	support	VERB
8s45q813n68	7	12	the	the	DET
8s45q813n68	7	13	basis	basis	NOUN
8s45q813n68	7	14	for	for	ADP
8s45q813n68	7	15	single	single	ADJ
8s45q813n68	7	16	-	-	PUNCT
8s45q813n68	7	17	molecule	molecule	NOUN
8s45q813n68	7	18	experiments.spectroelectrochemical	experiments.spectroelectrochemical	ADJ
8s45q813n68	7	19	measurements	measurement	NOUN
8s45q813n68	7	20	of	of	ADP
8s45q813n68	7	21	the	the	DET
8s45q813n68	7	22	redox	redox	ADJ
8s45q813n68	7	23	-	-	PUNCT
8s45q813n68	7	24	active	active	ADJ
8s45q813n68	7	25	fluorophore	fluorophore	NOUN
8s45q813n68	7	26	,	,	PUNCT
8s45q813n68	7	27	flavin	flavin	NOUN
8s45q813n68	7	28	mononucleotide	mononucleotide	PROPN
8s45q813n68	7	29	(	(	PUNCT
8s45q813n68	7	30	fmn	fmn	PROPN
8s45q813n68	7	31	)	)	PUNCT
8s45q813n68	7	32	,	,	PUNCT
8s45q813n68	7	33	were	be	AUX
8s45q813n68	7	34	performed	perform	VERB
8s45q813n68	7	35	at	at	ADP
8s45q813n68	7	36	single	single	ADJ
8s45q813n68	7	37	-	-	PUNCT
8s45q813n68	7	38	molecule	molecule	NOUN
8s45q813n68	7	39	concentrations	concentration	NOUN
8s45q813n68	7	40	in	in	ADP
8s45q813n68	7	41	a	a	DET
8s45q813n68	7	42	bulk	bulk	ADJ
8s45q813n68	7	43	solution	solution	NOUN
8s45q813n68	7	44	above	above	ADP
8s45q813n68	7	45	an	an	DET
8s45q813n68	7	46	indium	indium	NOUN
8s45q813n68	7	47	tin	tin	NOUN
8s45q813n68	7	48	oxide	oxide	NOUN
8s45q813n68	7	49	(	(	PUNCT
8s45q813n68	7	50	ito	ito	PROPN
8s45q813n68	7	51	)	)	PUNCT
8s45q813n68	7	52	electrode	electrode	NOUN
8s45q813n68	7	53	and	and	CCONJ
8s45q813n68	7	54	in	in	ADP
8s45q813n68	7	55	the	the	DET
8s45q813n68	7	56	approximately	approximately	ADV
8s45q813n68	7	57	200	200	NUM
8s45q813n68	7	58	zl	zl	NOUN
8s45q813n68	7	59	observation	observation	NOUN
8s45q813n68	7	60	volumes	volume	NOUN
8s45q813n68	7	61	of	of	ADP
8s45q813n68	7	62	individual	individual	ADJ
8s45q813n68	7	63	electrochemical	electrochemical	ADJ
8s45q813n68	7	64	zmws	zmws	NOUN
8s45q813n68	7	65	(	(	PUNCT
8s45q813n68	7	66	e	e	NOUN
8s45q813n68	7	67	-	-	NOUN
8s45q813n68	7	68	zmws	zmws	VERB
8s45q813n68	7	69	)	)	PUNCT
8s45q813n68	7	70	.	.	PUNCT
8s45q813n68	8	1	fluorescence	fluorescence	ADJ
8s45q813n68	8	2	analogs	analog	NOUN
8s45q813n68	8	3	of	of	ADP
8s45q813n68	8	4	standard	standard	ADJ
8s45q813n68	8	5	electrochemical	electrochemical	ADJ
8s45q813n68	8	6	experiments	experiment	NOUN
8s45q813n68	8	7	were	be	AUX
8s45q813n68	8	8	implemented	implement	VERB
8s45q813n68	8	9	.	.	PUNCT
8s45q813n68	9	1	these	these	PRON
8s45q813n68	9	2	are	be	AUX
8s45q813n68	9	3	fluorescence	fluorescence	ADJ
8s45q813n68	9	4	emission	emission	NOUN
8s45q813n68	9	5	under	under	ADP
8s45q813n68	9	6	static	static	ADJ
8s45q813n68	9	7	control	control	NOUN
8s45q813n68	9	8	and	and	CCONJ
8s45q813n68	9	9	chronofluorometry	chronofluorometry	NOUN
8s45q813n68	9	10	as	as	ADP
8s45q813n68	9	11	analogs	analog	NOUN
8s45q813n68	9	12	to	to	ADP
8s45q813n68	9	13	amperometry	amperometry	NOUN
8s45q813n68	9	14	,	,	PUNCT
8s45q813n68	9	15	and	and	CCONJ
8s45q813n68	9	16	cyclic	cyclic	VERB
8s45q813n68	9	17	potential	potential	ADJ
8s45q813n68	9	18	sweep	sweep	NOUN
8s45q813n68	9	19	fluorometry	fluorometry	NOUN
8s45q813n68	9	20	as	as	ADP
8s45q813n68	9	21	an	an	DET
8s45q813n68	9	22	analog	analog	NOUN
8s45q813n68	9	23	to	to	PART
8s45q813n68	9	24	cyclic	cyclic	VERB
8s45q813n68	9	25	voltammetry	voltammetry	NOUN
8s45q813n68	9	26	.	.	PUNCT
8s45q813n68	10	1	a	a	DET
8s45q813n68	10	2	long	long	ADV
8s45q813n68	10	3	-	-	PUNCT
8s45q813n68	10	4	lived	live	VERB
8s45q813n68	10	5	semiquinone	semiquinone	ADJ
8s45q813n68	10	6	state	state	NOUN
8s45q813n68	10	7	of	of	ADP
8s45q813n68	10	8	fmn	fmn	PROPN
8s45q813n68	10	9	was	be	AUX
8s45q813n68	10	10	stabilized	stabilize	VERB
8s45q813n68	10	11	and	and	CCONJ
8s45q813n68	10	12	observed	observe	VERB
8s45q813n68	10	13	in	in	ADP
8s45q813n68	10	14	a	a	DET
8s45q813n68	10	15	zmw	zmw	NOUN
8s45q813n68	10	16	.	.	PUNCT
8s45q813n68	11	1	the	the	DET
8s45q813n68	11	2	work	work	NOUN
8s45q813n68	11	3	in	in	ADP
8s45q813n68	11	4	this	this	DET
8s45q813n68	11	5	dissertation	dissertation	NOUN
8s45q813n68	11	6	represents	represent	VERB
8s45q813n68	11	7	the	the	DET
8s45q813n68	11	8	first	first	ADJ
8s45q813n68	11	9	single	single	ADJ
8s45q813n68	11	10	-	-	PUNCT
8s45q813n68	11	11	molecule	molecule	NOUN
8s45q813n68	11	12	spectroelectrochemistry	spectroelectrochemistry	NOUN
8s45q813n68	11	13	investigations	investigation	NOUN
8s45q813n68	11	14	in	in	ADP
8s45q813n68	11	15	an	an	DET
8s45q813n68	11	16	e	e	NOUN
8s45q813n68	11	17	-	-	ADJ
8s45q813n68	11	18	zmw	zmw	ADJ
8s45q813n68	11	19	nanophotonic	nanophotonic	ADJ
8s45q813n68	11	20	structure	structure	NOUN
8s45q813n68	11	21	.	.	PUNCT
8s45q813n68	12	1	means	mean	NOUN
8s45q813n68	12	2	of	of	ADP
8s45q813n68	12	3	improving	improve	VERB
8s45q813n68	12	4	the	the	DET
8s45q813n68	12	5	performance	performance	NOUN
8s45q813n68	12	6	of	of	ADP
8s45q813n68	12	7	the	the	DET
8s45q813n68	12	8	fcs	fcs	ADJ
8s45q813n68	12	9	optical	optical	ADJ
8s45q813n68	12	10	system	system	NOUN
8s45q813n68	12	11	and	and	CCONJ
8s45q813n68	12	12	expanding	expand	VERB
8s45q813n68	12	13	its	its	PRON
8s45q813n68	12	14	capabilities	capability	NOUN
8s45q813n68	12	15	are	be	AUX
8s45q813n68	12	16	explored	explore	VERB
8s45q813n68	12	17	.	.	PUNCT
8s45q813n68	13	1	experimental	experimental	ADJ
8s45q813n68	13	2	modifications	modification	NOUN
8s45q813n68	13	3	,	,	PUNCT
8s45q813n68	13	4	device	device	NOUN
8s45q813n68	13	5	design	design	NOUN
8s45q813n68	13	6	variations	variation	NOUN
8s45q813n68	13	7	,	,	PUNCT
8s45q813n68	13	8	and	and	CCONJ
8s45q813n68	13	9	other	other	ADJ
8s45q813n68	13	10	possible	possible	ADJ
8s45q813n68	13	11	redox	redox	ADJ
8s45q813n68	13	12	-	-	PUNCT
8s45q813n68	13	13	active	active	ADJ
8s45q813n68	13	14	chemical	chemical	NOUN
8s45q813n68	13	15	systems	system	NOUN
8s45q813n68	13	16	are	be	AUX
8s45q813n68	13	17	discussed	discuss	VERB
8s45q813n68	13	18	.	.	PUNCT