id sid tid token lemma pos 8k71ng4715d 1 1 mitosis mitosis NOUN 8k71ng4715d 1 2 is be AUX 8k71ng4715d 1 3 a a DET 8k71ng4715d 1 4 series series NOUN 8k71ng4715d 1 5 of of ADP 8k71ng4715d 1 6 intricate intricate ADJ 8k71ng4715d 1 7 and and CCONJ 8k71ng4715d 1 8 complex complex ADJ 8k71ng4715d 1 9 events event NOUN 8k71ng4715d 1 10 that that PRON 8k71ng4715d 1 11 take take VERB 8k71ng4715d 1 12 place place NOUN 8k71ng4715d 1 13 during during ADP 8k71ng4715d 1 14 each each DET 8k71ng4715d 1 15 cell cell NOUN 8k71ng4715d 1 16 cycle cycle NOUN 8k71ng4715d 1 17 . . PUNCT 8k71ng4715d 2 1 regulation regulation NOUN 8k71ng4715d 2 2 of of ADP 8k71ng4715d 2 3 mitosis mitosis NOUN 8k71ng4715d 2 4 is be AUX 8k71ng4715d 2 5 especially especially ADV 8k71ng4715d 2 6 important important ADJ 8k71ng4715d 2 7 at at ADP 8k71ng4715d 2 8 the the DET 8k71ng4715d 2 9 kinetochore kinetochore NOUN 8k71ng4715d 2 10 , , PUNCT 8k71ng4715d 2 11 the the DET 8k71ng4715d 2 12 protein protein NOUN 8k71ng4715d 2 13 - - PUNCT 8k71ng4715d 2 14 rich rich ADJ 8k71ng4715d 2 15 area area NOUN 8k71ng4715d 2 16 between between ADP 8k71ng4715d 2 17 the the DET 8k71ng4715d 2 18 chromosome chromosome NOUN 8k71ng4715d 2 19 arms arm NOUN 8k71ng4715d 2 20 . . PUNCT 8k71ng4715d 3 1 kinetochores kinetochore NOUN 8k71ng4715d 3 2 are be AUX 8k71ng4715d 3 3 required require VERB 8k71ng4715d 3 4 for for ADP 8k71ng4715d 3 5 several several ADJ 8k71ng4715d 3 6 aspects aspect NOUN 8k71ng4715d 3 7 of of ADP 8k71ng4715d 3 8 mitosis mitosis NOUN 8k71ng4715d 3 9 , , PUNCT 8k71ng4715d 3 10 including include VERB 8k71ng4715d 3 11 initial initial ADJ 8k71ng4715d 3 12 interactions interaction NOUN 8k71ng4715d 3 13 between between ADP 8k71ng4715d 3 14 chromosomes chromosome NOUN 8k71ng4715d 3 15 and and CCONJ 8k71ng4715d 3 16 microtubules microtubule NOUN 8k71ng4715d 3 17 ( ( PUNCT 8k71ng4715d 3 18 mts mts NOUN 8k71ng4715d 3 19 ) ) PUNCT 8k71ng4715d 3 20 , , PUNCT 8k71ng4715d 3 21 chromosome chromosome NOUN 8k71ng4715d 3 22 movement movement NOUN 8k71ng4715d 3 23 , , PUNCT 8k71ng4715d 3 24 and and CCONJ 8k71ng4715d 3 25 activities activity NOUN 8k71ng4715d 3 26 associated associate VERB 8k71ng4715d 3 27 with with ADP 8k71ng4715d 3 28 the the DET 8k71ng4715d 3 29 spindle spindle NOUN 8k71ng4715d 3 30 assembly assembly NOUN 8k71ng4715d 3 31 checkpoint checkpoint NOUN 8k71ng4715d 3 32 ( ( PUNCT 8k71ng4715d 3 33 sac sac NOUN 8k71ng4715d 3 34 ) ) PUNCT 8k71ng4715d 3 35 . . PUNCT 8k71ng4715d 4 1 cytoplasmic cytoplasmic ADJ 8k71ng4715d 4 2 dynein dynein PROPN 8k71ng4715d 4 3 plays play VERB 8k71ng4715d 4 4 a a DET 8k71ng4715d 4 5 role role NOUN 8k71ng4715d 4 6 in in ADP 8k71ng4715d 4 7 one one NUM 8k71ng4715d 4 8 or or CCONJ 8k71ng4715d 4 9 more more ADJ 8k71ng4715d 4 10 of of ADP 8k71ng4715d 4 11 these these DET 8k71ng4715d 4 12 kinetochore kinetochore NOUN 8k71ng4715d 4 13 functions function NOUN 8k71ng4715d 4 14 ; ; PUNCT 8k71ng4715d 4 15 however however ADV 8k71ng4715d 4 16 , , PUNCT 8k71ng4715d 4 17 the the DET 8k71ng4715d 4 18 specific specific ADJ 8k71ng4715d 4 19 contributions contribution NOUN 8k71ng4715d 4 20 of of ADP 8k71ng4715d 4 21 dynein dynein NOUN 8k71ng4715d 4 22 remain remain VERB 8k71ng4715d 4 23 under under ADP 8k71ng4715d 4 24 investigation investigation NOUN 8k71ng4715d 4 25 . . PUNCT 8k71ng4715d 5 1 recent recent ADJ 8k71ng4715d 5 2 work work NOUN 8k71ng4715d 5 3 has have AUX 8k71ng4715d 5 4 suggested suggest VERB 8k71ng4715d 5 5 a a DET 8k71ng4715d 5 6 linked link VERB 8k71ng4715d 5 7 between between ADP 8k71ng4715d 5 8 cytoplasmic cytoplasmic ADJ 8k71ng4715d 5 9 dynein dynein NOUN 8k71ng4715d 5 10 regulation regulation NOUN 8k71ng4715d 5 11 and and CCONJ 8k71ng4715d 5 12 kinetochore kinetochore PROPN 8k71ng4715d 5 13 kinases kinases PROPN 8k71ng4715d 5 14 aurora aurora PROPN 8k71ng4715d 5 15 b b PROPN 8k71ng4715d 5 16 and and CCONJ 8k71ng4715d 5 17 mps-1 mps-1 X 8k71ng4715d 5 18 . . PROPN 8k71ng4715d 5 19 aurora aurora PROPN 8k71ng4715d 5 20 b b PROPN 8k71ng4715d 5 21 is be AUX 8k71ng4715d 5 22 an an DET 8k71ng4715d 5 23 essential essential ADJ 8k71ng4715d 5 24 mitotic mitotic ADJ 8k71ng4715d 5 25 kinase kinase NOUN 8k71ng4715d 5 26 that that PRON 8k71ng4715d 5 27 regulates regulate VERB 8k71ng4715d 5 28 several several ADJ 8k71ng4715d 5 29 aspects aspect NOUN 8k71ng4715d 5 30 of of ADP 8k71ng4715d 5 31 the the DET 8k71ng4715d 5 32 spindle spindle NOUN 8k71ng4715d 5 33 assembly assembly NOUN 8k71ng4715d 5 34 checkpoint checkpoint NOUN 8k71ng4715d 5 35 ( ( PUNCT 8k71ng4715d 5 36 sac sac NOUN 8k71ng4715d 5 37 ) ) PUNCT 8k71ng4715d 5 38 . . PUNCT 8k71ng4715d 6 1 because because SCONJ 8k71ng4715d 6 2 of of ADP 8k71ng4715d 6 3 this this DET 8k71ng4715d 6 4 known know VERB 8k71ng4715d 6 5 function function NOUN 8k71ng4715d 6 6 , , PUNCT 8k71ng4715d 6 7 we we PRON 8k71ng4715d 6 8 investigated investigate VERB 8k71ng4715d 6 9 the the DET 8k71ng4715d 6 10 role role NOUN 8k71ng4715d 6 11 aurora aurora PROPN 8k71ng4715d 6 12 b b PROPN 8k71ng4715d 6 13 activity activity NOUN 8k71ng4715d 6 14 plays play VERB 8k71ng4715d 6 15 in in ADP 8k71ng4715d 6 16 recruitment recruitment NOUN 8k71ng4715d 6 17 of of ADP 8k71ng4715d 6 18 dynein dynein NOUN 8k71ng4715d 6 19 to to ADP 8k71ng4715d 6 20 the the DET 8k71ng4715d 6 21 kinetochore kinetochore NOUN 8k71ng4715d 6 22 . . PUNCT 8k71ng4715d 7 1 our our PRON 8k71ng4715d 7 2 study study NOUN 8k71ng4715d 7 3 determined determine VERB 8k71ng4715d 7 4 that that SCONJ 8k71ng4715d 7 5 aurora aurora PROPN 8k71ng4715d 7 6 b b PROPN 8k71ng4715d 7 7 activity activity NOUN 8k71ng4715d 7 8 works work VERB 8k71ng4715d 7 9 upstream upstream ADV 8k71ng4715d 7 10 of of ADP 8k71ng4715d 7 11 the the DET 8k71ng4715d 7 12 fibrous fibrous ADJ 8k71ng4715d 7 13 corona corona NOUN 8k71ng4715d 7 14 and and CCONJ 8k71ng4715d 7 15 is be AUX 8k71ng4715d 7 16 required require VERB 8k71ng4715d 7 17 for for ADP 8k71ng4715d 7 18 the the DET 8k71ng4715d 7 19 proper proper ADJ 8k71ng4715d 7 20 recruitment recruitment NOUN 8k71ng4715d 7 21 of of ADP 8k71ng4715d 7 22 dynein dynein NOUN 8k71ng4715d 7 23 to to ADP 8k71ng4715d 7 24 the the DET 8k71ng4715d 7 25 kinetochore kinetochore NOUN 8k71ng4715d 7 26 through through ADP 8k71ng4715d 7 27 regulation regulation NOUN 8k71ng4715d 7 28 of of ADP 8k71ng4715d 7 29 dynein dynein NOUN 8k71ng4715d 7 30 - - PUNCT 8k71ng4715d 7 31 binding bind VERB 8k71ng4715d 7 32 platform platform NOUN 8k71ng4715d 7 33 assembly assembly NOUN 8k71ng4715d 7 34 . . PUNCT 8k71ng4715d 8 1 specifically specifically ADV 8k71ng4715d 8 2 , , PUNCT 8k71ng4715d 8 3 aurora aurora PROPN 8k71ng4715d 8 4 b b PROPN 8k71ng4715d 8 5 activity activity NOUN 8k71ng4715d 8 6 regulates regulate VERB 8k71ng4715d 8 7 the the DET 8k71ng4715d 8 8 interaction interaction NOUN 8k71ng4715d 8 9 between between ADP 8k71ng4715d 8 10 zwint-1 zwint-1 NUM 8k71ng4715d 8 11 and and CCONJ 8k71ng4715d 8 12 zw10 zw10 PROPN 8k71ng4715d 8 13 through through ADP 8k71ng4715d 8 14 direct direct ADJ 8k71ng4715d 8 15 phosphorylation phosphorylation NOUN 8k71ng4715d 8 16 of of ADP 8k71ng4715d 8 17 zwint-1 zwint-1 NUM 8k71ng4715d 8 18 . . PUNCT 8k71ng4715d 9 1 further further ADJ 8k71ng4715d 9 2 work work NOUN 8k71ng4715d 9 3 revealed reveal VERB 8k71ng4715d 9 4 that that SCONJ 8k71ng4715d 9 5 phosphorylation phosphorylation NOUN 8k71ng4715d 9 6 and and CCONJ 8k71ng4715d 9 7 dephosphorylation dephosphorylation NOUN 8k71ng4715d 9 8 of of ADP 8k71ng4715d 9 9 zwint-1are zwint-1are NOUN 8k71ng4715d 9 10 necessary necessary ADJ 8k71ng4715d 9 11 for for ADP 8k71ng4715d 9 12 accurate accurate ADJ 8k71ng4715d 9 13 significantly significantly ADV 8k71ng4715d 9 14 impact impact VERB 8k71ng4715d 9 15 mitotic mitotic ADJ 8k71ng4715d 9 16 progression progression NOUN 8k71ng4715d 9 17 . . PUNCT 8k71ng4715d 10 1 zwint-1 zwint-1 NUM 8k71ng4715d 10 2 phosphorylation phosphorylation NOUN 8k71ng4715d 10 3 is be AUX 8k71ng4715d 10 4 required require VERB 8k71ng4715d 10 5 during during ADP 8k71ng4715d 10 6 prometaphase prometaphase NOUN 8k71ng4715d 10 7 for for ADP 8k71ng4715d 10 8 proper proper ADJ 8k71ng4715d 10 9 assembly assembly NOUN 8k71ng4715d 10 10 of of ADP 8k71ng4715d 10 11 the the DET 8k71ng4715d 10 12 kinetochore kinetochore NOUN 8k71ng4715d 10 13 and and CCONJ 8k71ng4715d 10 14 coordinated coordinate VERB 8k71ng4715d 10 15 zwint-1 zwint-1 NUM 8k71ng4715d 10 16 dephoshorylation dephoshorylation NOUN 8k71ng4715d 10 17 is be AUX 8k71ng4715d 10 18 required require VERB 8k71ng4715d 10 19 for for ADP 8k71ng4715d 10 20 entrance entrance NOUN 8k71ng4715d 10 21 into into ADP 8k71ng4715d 10 22 anaphase anaphase NOUN 8k71ng4715d 10 23 and and CCONJ 8k71ng4715d 10 24 sac sac NOUN 8k71ng4715d 10 25 silencing silencing NOUN 8k71ng4715d 10 26 . . PUNCT 8k71ng4715d 11 1 previous previous ADJ 8k71ng4715d 11 2 work work NOUN 8k71ng4715d 11 3 has have AUX 8k71ng4715d 11 4 determined determine VERB 8k71ng4715d 11 5 that that SCONJ 8k71ng4715d 11 6 aurora aurora PROPN 8k71ng4715d 11 7 b b PROPN 8k71ng4715d 11 8 and and CCONJ 8k71ng4715d 11 9 mps-1 mps-1 PRON 8k71ng4715d 11 10 have have AUX 8k71ng4715d 11 11 overlapping overlap VERB 8k71ng4715d 11 12 regulatory regulatory ADJ 8k71ng4715d 11 13 roles role NOUN 8k71ng4715d 11 14 in in ADP 8k71ng4715d 11 15 kinetochore kinetochore NOUN 8k71ng4715d 11 16 - - PUNCT 8k71ng4715d 11 17 based base VERB 8k71ng4715d 11 18 mechanisms mechanism NOUN 8k71ng4715d 11 19 that that PRON 8k71ng4715d 11 20 may may AUX 8k71ng4715d 11 21 be be AUX 8k71ng4715d 11 22 due due ADJ 8k71ng4715d 11 23 to to ADP 8k71ng4715d 11 24 evolutionary evolutionary ADJ 8k71ng4715d 11 25 redundancy redundancy NOUN 8k71ng4715d 11 26 . . PUNCT 8k71ng4715d 12 1 it it PRON 8k71ng4715d 12 2 was be AUX 8k71ng4715d 12 3 determined determine VERB 8k71ng4715d 12 4 that that SCONJ 8k71ng4715d 12 5 aurora aurora PROPN 8k71ng4715d 12 6 b b PROPN 8k71ng4715d 12 7 and and CCONJ 8k71ng4715d 12 8 mps-1 mps-1 ADP 8k71ng4715d 12 9 inhibition inhibition NOUN 8k71ng4715d 12 10 give give VERB 8k71ng4715d 12 11 similar similar ADJ 8k71ng4715d 12 12 assembly assembly NOUN 8k71ng4715d 12 13 defects defect NOUN 8k71ng4715d 12 14 in in ADP 8k71ng4715d 12 15 the the DET 8k71ng4715d 12 16 dynein dynein NOUN 8k71ng4715d 12 17 - - PUNCT 8k71ng4715d 12 18 binding bind VERB 8k71ng4715d 12 19 platform platform NOUN 8k71ng4715d 12 20 ; ; PUNCT 8k71ng4715d 12 21 however however ADV 8k71ng4715d 12 22 these these DET 8k71ng4715d 12 23 defects defect NOUN 8k71ng4715d 12 24 arise arise VERB 8k71ng4715d 12 25 from from ADP 8k71ng4715d 12 26 different different ADJ 8k71ng4715d 12 27 mechanisms mechanism NOUN 8k71ng4715d 12 28 . . PUNCT 8k71ng4715d 13 1 this this DET 8k71ng4715d 13 2 study study NOUN 8k71ng4715d 13 3 demonstrated demonstrate VERB 8k71ng4715d 13 4 that that SCONJ 8k71ng4715d 13 5 mps-1 mps-1 ADP 8k71ng4715d 13 6 and and CCONJ 8k71ng4715d 13 7 aurora aurora PROPN 8k71ng4715d 13 8 b b PROPN 8k71ng4715d 13 9 do do AUX 8k71ng4715d 13 10 not not PART 8k71ng4715d 13 11 have have VERB 8k71ng4715d 13 12 substrate substrate NOUN 8k71ng4715d 13 13 redundancy redundancy NOUN 8k71ng4715d 13 14 and and CCONJ 8k71ng4715d 13 15 that that PRON 8k71ng4715d 13 16 mps-1 mps-1 VERB 8k71ng4715d 13 17 directly directly ADV 8k71ng4715d 13 18 phosphorylates phosphorylate VERB 8k71ng4715d 13 19 zwilch zwilch PROPN 8k71ng4715d 13 20 in in ADP 8k71ng4715d 13 21 the the DET 8k71ng4715d 13 22 rzz rzz NOUN 8k71ng4715d 13 23 complex complex NOUN 8k71ng4715d 13 24 , , PUNCT 8k71ng4715d 13 25 whereas whereas SCONJ 8k71ng4715d 13 26 aurora aurora PROPN 8k71ng4715d 13 27 b b PROPN 8k71ng4715d 13 28 directly directly ADV 8k71ng4715d 13 29 phosphorylates phosphorylate VERB 8k71ng4715d 13 30 zwint-1 zwint-1 NUM 8k71ng4715d 13 31 . . PUNCT 8k71ng4715d 14 1 overall overall ADV 8k71ng4715d 14 2 , , PUNCT 8k71ng4715d 14 3 these these DET 8k71ng4715d 14 4 findings finding NOUN 8k71ng4715d 14 5 provide provide VERB 8k71ng4715d 14 6 a a DET 8k71ng4715d 14 7 better well ADJ 8k71ng4715d 14 8 understanding understanding NOUN 8k71ng4715d 14 9 of of ADP 8k71ng4715d 14 10 proper proper ADJ 8k71ng4715d 14 11 kinetochore kinetochore NOUN 8k71ng4715d 14 12 assembly assembly NOUN 8k71ng4715d 14 13 and and CCONJ 8k71ng4715d 14 14 regulation regulation NOUN 8k71ng4715d 14 15 of of ADP 8k71ng4715d 14 16 the the DET 8k71ng4715d 14 17 sac sac NOUN 8k71ng4715d 14 18 by by ADP 8k71ng4715d 14 19 phosphorylation phosphorylation NOUN 8k71ng4715d 14 20 . . PUNCT