id	sid	tid	token	lemma	pos
8g84mk63r83	1	1	the	the	DET
8g84mk63r83	1	2	current	current	ADJ
8g84mk63r83	1	3	gold	gold	NOUN
8g84mk63r83	1	4	standard	standard	NOUN
8g84mk63r83	1	5	for	for	ADP
8g84mk63r83	1	6	bone	bone	NOUN
8g84mk63r83	1	7	repair	repair	NOUN
8g84mk63r83	1	8	,	,	PUNCT
8g84mk63r83	1	9	autologous	autologous	ADJ
8g84mk63r83	1	10	bone	bone	NOUN
8g84mk63r83	1	11	graft	graft	NOUN
8g84mk63r83	1	12	,	,	PUNCT
8g84mk63r83	1	13	is	be	AUX
8g84mk63r83	1	14	costly	costly	ADJ
8g84mk63r83	1	15	and	and	CCONJ
8g84mk63r83	1	16	destructive	destructive	ADJ
8g84mk63r83	1	17	to	to	ADP
8g84mk63r83	1	18	the	the	DET
8g84mk63r83	1	19	harvest	harvest	NOUN
8g84mk63r83	1	20	site	site	NOUN
8g84mk63r83	1	21	.	.	PUNCT
8g84mk63r83	2	1	moreover	moreover	ADV
8g84mk63r83	2	2	,	,	PUNCT
8g84mk63r83	2	3	the	the	DET
8g84mk63r83	2	4	amount	amount	NOUN
8g84mk63r83	2	5	of	of	ADP
8g84mk63r83	2	6	available	available	ADJ
8g84mk63r83	2	7	donor	donor	NOUN
8g84mk63r83	2	8	tissue	tissue	NOUN
8g84mk63r83	2	9	is	be	AUX
8g84mk63r83	2	10	limited	limited	ADJ
8g84mk63r83	2	11	,	,	PUNCT
8g84mk63r83	2	12	so	so	CCONJ
8g84mk63r83	2	13	it	it	PRON
8g84mk63r83	2	14	is	be	AUX
8g84mk63r83	2	15	not	not	PART
8g84mk63r83	2	16	always	always	ADV
8g84mk63r83	2	17	a	a	DET
8g84mk63r83	2	18	viable	viable	ADJ
8g84mk63r83	2	19	option	option	NOUN
8g84mk63r83	2	20	.	.	PUNCT
8g84mk63r83	3	1	the	the	DET
8g84mk63r83	3	2	aim	aim	NOUN
8g84mk63r83	3	3	of	of	ADP
8g84mk63r83	3	4	this	this	DET
8g84mk63r83	3	5	work	work	NOUN
8g84mk63r83	3	6	was	be	AUX
8g84mk63r83	3	7	to	to	PART
8g84mk63r83	3	8	investigate	investigate	VERB
8g84mk63r83	3	9	tissue	tissue	NOUN
8g84mk63r83	3	10	engineering	engineering	NOUN
8g84mk63r83	3	11	as	as	ADP
8g84mk63r83	3	12	an	an	DET
8g84mk63r83	3	13	alternative	alternative	NOUN
8g84mk63r83	3	14	to	to	ADP
8g84mk63r83	3	15	autograft	autograft	NOUN
8g84mk63r83	3	16	-	-	PUNCT
8g84mk63r83	3	17	based	base	VERB
8g84mk63r83	3	18	bone	bone	NOUN
8g84mk63r83	3	19	repair	repair	NOUN
8g84mk63r83	3	20	through	through	ADP
8g84mk63r83	3	21	the	the	DET
8g84mk63r83	3	22	combination	combination	NOUN
8g84mk63r83	3	23	of	of	ADP
8g84mk63r83	3	24	donor	donor	NOUN
8g84mk63r83	3	25	cells	cell	NOUN
8g84mk63r83	3	26	and	and	CCONJ
8g84mk63r83	3	27	three	three	NUM
8g84mk63r83	3	28	-	-	PUNCT
8g84mk63r83	3	29	dimensional	dimensional	ADJ
8g84mk63r83	3	30	cell	cell	NOUN
8g84mk63r83	3	31	carriers	carrier	NOUN
8g84mk63r83	3	32	.	.	PUNCT
8g84mk63r83	4	1	the	the	DET
8g84mk63r83	4	2	results	result	NOUN
8g84mk63r83	4	3	presented	present	VERB
8g84mk63r83	4	4	herein	herein	ADV
8g84mk63r83	4	5	describe	describe	VERB
8g84mk63r83	4	6	the	the	DET
8g84mk63r83	4	7	progress	progress	NOUN
8g84mk63r83	4	8	made	make	VERB
8g84mk63r83	4	9	toward	toward	ADP
8g84mk63r83	4	10	that	that	DET
8g84mk63r83	4	11	goal	goal	NOUN
8g84mk63r83	4	12	.	.	PUNCT
8g84mk63r83	5	1	to	to	PART
8g84mk63r83	5	2	evaluate	evaluate	VERB
8g84mk63r83	5	3	the	the	DET
8g84mk63r83	5	4	intramembranous	intramembranous	ADJ
8g84mk63r83	5	5	bone	bone	NOUN
8g84mk63r83	5	6	forming	form	VERB
8g84mk63r83	5	7	capacity	capacity	NOUN
8g84mk63r83	5	8	of	of	ADP
8g84mk63r83	5	9	human	human	ADJ
8g84mk63r83	5	10	adipose	adipose	NOUN
8g84mk63r83	5	11	-	-	PUNCT
8g84mk63r83	5	12	derived	derive	VERB
8g84mk63r83	5	13	stem	stem	NOUN
8g84mk63r83	5	14	cells	cell	NOUN
8g84mk63r83	5	15	,	,	PUNCT
8g84mk63r83	5	16	novel	novel	ADJ
8g84mk63r83	5	17	collagen	collagen	NOUN
8g84mk63r83	5	18	scaffolds	scaffold	NOUN
8g84mk63r83	5	19	with	with	ADP
8g84mk63r83	5	20	or	or	CCONJ
8g84mk63r83	5	21	without	without	ADP
8g84mk63r83	5	22	hydroxyapatite	hydroxyapatite	NOUN
8g84mk63r83	5	23	reinforcement	reinforcement	NOUN
8g84mk63r83	5	24	were	be	AUX
8g84mk63r83	5	25	loaded	load	VERB
8g84mk63r83	5	26	with	with	ADP
8g84mk63r83	5	27	cells	cell	NOUN
8g84mk63r83	5	28	and	and	CCONJ
8g84mk63r83	5	29	treated	treat	VERB
8g84mk63r83	5	30	with	with	ADP
8g84mk63r83	5	31	growth	growth	NOUN
8g84mk63r83	5	32	or	or	CCONJ
8g84mk63r83	5	33	an	an	DET
8g84mk63r83	5	34	osteogenic	osteogenic	ADJ
8g84mk63r83	5	35	differentiation	differentiation	NOUN
8g84mk63r83	5	36	medium	medium	NOUN
8g84mk63r83	5	37	.	.	PUNCT
8g84mk63r83	6	1	upon	upon	SCONJ
8g84mk63r83	6	2	implantation	implantation	NOUN
8g84mk63r83	6	3	,	,	PUNCT
8g84mk63r83	6	4	the	the	DET
8g84mk63r83	6	5	cell	cell	NOUN
8g84mk63r83	6	6	-	-	PUNCT
8g84mk63r83	6	7	scaffold	scaffold	NOUN
8g84mk63r83	6	8	constructs	construct	NOUN
8g84mk63r83	6	9	produced	produce	VERB
8g84mk63r83	6	10	varying	vary	VERB
8g84mk63r83	6	11	amounts	amount	NOUN
8g84mk63r83	6	12	of	of	ADP
8g84mk63r83	6	13	immature	immature	ADJ
8g84mk63r83	6	14	bone	bone	NOUN
8g84mk63r83	6	15	characterized	characterize	VERB
8g84mk63r83	6	16	by	by	ADP
8g84mk63r83	6	17	highly	highly	ADV
8g84mk63r83	6	18	vascularized	vascularized	ADJ
8g84mk63r83	6	19	osteocalcin	osteocalcin	NOUN
8g84mk63r83	6	20	and	and	CCONJ
8g84mk63r83	6	21	osteopontin	osteopontin	NOUN
8g84mk63r83	6	22	-	-	PUNCT
8g84mk63r83	6	23	positive	positive	ADJ
8g84mk63r83	6	24	matrix	matrix	NOUN
8g84mk63r83	6	25	and	and	CCONJ
8g84mk63r83	6	26	an	an	DET
8g84mk63r83	6	27	increase	increase	NOUN
8g84mk63r83	6	28	in	in	ADP
8g84mk63r83	6	29	mineralized	mineralized	ADJ
8g84mk63r83	6	30	tissue	tissue	NOUN
8g84mk63r83	6	31	volume	volume	NOUN
8g84mk63r83	6	32	.	.	PUNCT
8g84mk63r83	7	1	hydroxyapatite	hydroxyapatite	NOUN
8g84mk63r83	7	2	reinforcement	reinforcement	NOUN
8g84mk63r83	7	3	and	and	CCONJ
8g84mk63r83	7	4	the	the	DET
8g84mk63r83	7	5	particular	particular	ADJ
8g84mk63r83	7	6	pretreatment	pretreatment	NOUN
8g84mk63r83	7	7	of	of	ADP
8g84mk63r83	7	8	the	the	DET
8g84mk63r83	7	9	cells	cell	NOUN
8g84mk63r83	7	10	were	be	AUX
8g84mk63r83	7	11	identified	identify	VERB
8g84mk63r83	7	12	as	as	ADP
8g84mk63r83	7	13	key	key	ADJ
8g84mk63r83	7	14	factors	factor	NOUN
8g84mk63r83	7	15	influencing	influence	VERB
8g84mk63r83	7	16	tissue	tissue	NOUN
8g84mk63r83	7	17	formation	formation	NOUN
8g84mk63r83	7	18	in	in	ADP
8g84mk63r83	7	19	vivo	vivo	PROPN
8g84mk63r83	7	20	.	.	PUNCT
8g84mk63r83	8	1	in	in	SCONJ
8g84mk63r83	8	2	order	order	NOUN
8g84mk63r83	8	3	to	to	PART
8g84mk63r83	8	4	determine	determine	VERB
8g84mk63r83	8	5	important	important	ADJ
8g84mk63r83	8	6	characteristics	characteristic	NOUN
8g84mk63r83	8	7	for	for	ADP
8g84mk63r83	8	8	engineered	engineer	VERB
8g84mk63r83	8	9	constructs	construct	NOUN
8g84mk63r83	8	10	capable	capable	ADJ
8g84mk63r83	8	11	of	of	ADP
8g84mk63r83	8	12	inducing	induce	VERB
8g84mk63r83	8	13	an	an	DET
8g84mk63r83	8	14	endochondral	endochondral	ADJ
8g84mk63r83	8	15	response	response	NOUN
8g84mk63r83	8	16	in	in	ADP
8g84mk63r83	8	17	vivo	vivo	PROPN
8g84mk63r83	8	18	,	,	PUNCT
8g84mk63r83	8	19	an	an	DET
8g84mk63r83	8	20	ectopic	ectopic	ADJ
8g84mk63r83	8	21	model	model	NOUN
8g84mk63r83	8	22	of	of	ADP
8g84mk63r83	8	23	endochondral	endochondral	ADJ
8g84mk63r83	8	24	ossification	ossification	NOUN
8g84mk63r83	8	25	was	be	AUX
8g84mk63r83	8	26	developed	develop	VERB
8g84mk63r83	8	27	with	with	ADP
8g84mk63r83	8	28	pre	pre	ADJ
8g84mk63r83	8	29	-	-	ADJ
8g84mk63r83	8	30	chondrogenic	chondrogenic	ADJ
8g84mk63r83	8	31	murine	murine	NOUN
8g84mk63r83	8	32	cell	cell	NOUN
8g84mk63r83	8	33	line	line	NOUN
8g84mk63r83	8	34	atdc5	atdc5	PROPN
8g84mk63r83	8	35	.	.	PUNCT
8g84mk63r83	9	1	when	when	SCONJ
8g84mk63r83	9	2	coupled	couple	VERB
8g84mk63r83	9	3	with	with	ADP
8g84mk63r83	9	4	an	an	DET
8g84mk63r83	9	5	osteoinductive	osteoinductive	ADJ
8g84mk63r83	9	6	scaffold	scaffold	NOUN
8g84mk63r83	9	7	in	in	ADP
8g84mk63r83	9	8	vivo	vivo	PROPN
8g84mk63r83	9	9	,	,	PUNCT
8g84mk63r83	9	10	pellets	pellet	NOUN
8g84mk63r83	9	11	been	be	AUX
8g84mk63r83	9	12	pre	pre	VERB
8g84mk63r83	9	13	-	-	VERB
8g84mk63r83	9	14	treated	treat	VERB
8g84mk63r83	9	15	in	in	ADP
8g84mk63r83	9	16	an	an	DET
8g84mk63r83	9	17	optimized	optimize	VERB
8g84mk63r83	9	18	chondrogenic	chondrogenic	NOUN
8g84mk63r83	9	19	differentiation	differentiation	NOUN
8g84mk63r83	9	20	medium	medium	NOUN
8g84mk63r83	9	21	underwent	undergo	VERB
8g84mk63r83	9	22	chondrogenic	chondrogenic	ADJ
8g84mk63r83	9	23	maturation	maturation	NOUN
8g84mk63r83	9	24	and	and	CCONJ
8g84mk63r83	9	25	partial	partial	ADJ
8g84mk63r83	9	26	ossification	ossification	NOUN
8g84mk63r83	9	27	over	over	ADP
8g84mk63r83	9	28	the	the	DET
8g84mk63r83	9	29	course	course	NOUN
8g84mk63r83	9	30	of	of	ADP
8g84mk63r83	9	31	8	8	NUM
8g84mk63r83	9	32	weeks	week	NOUN
8g84mk63r83	9	33	.	.	PUNCT
8g84mk63r83	10	1	this	this	DET
8g84mk63r83	10	2	effect	effect	NOUN
8g84mk63r83	10	3	was	be	AUX
8g84mk63r83	10	4	dependent	dependent	ADJ
8g84mk63r83	10	5	on	on	ADP
8g84mk63r83	10	6	the	the	DET
8g84mk63r83	10	7	treatment	treatment	NOUN
8g84mk63r83	10	8	medium	medium	NOUN
8g84mk63r83	10	9	applied	apply	VERB
8g84mk63r83	10	10	and	and	CCONJ
8g84mk63r83	10	11	a	a	DET
8g84mk63r83	10	12	three	three	NUM
8g84mk63r83	10	13	-	-	PUNCT
8g84mk63r83	10	14	dimensional	dimensional	ADJ
8g84mk63r83	10	15	culture	culture	NOUN
8g84mk63r83	10	16	environment	environment	NOUN
8g84mk63r83	10	17	.	.	PUNCT
8g84mk63r83	11	1	with	with	ADP
8g84mk63r83	11	2	these	these	DET
8g84mk63r83	11	3	findings	finding	NOUN
8g84mk63r83	11	4	in	in	ADP
8g84mk63r83	11	5	mind	mind	NOUN
8g84mk63r83	11	6	,	,	PUNCT
8g84mk63r83	11	7	chondrogenic	chondrogenic	ADJ
8g84mk63r83	11	8	treatment	treatment	NOUN
8g84mk63r83	11	9	was	be	AUX
8g84mk63r83	11	10	applied	apply	VERB
8g84mk63r83	11	11	to	to	ADP
8g84mk63r83	11	12	human	human	ADJ
8g84mk63r83	11	13	adipose	adipose	NOUN
8g84mk63r83	11	14	-	-	PUNCT
8g84mk63r83	11	15	derived	derive	VERB
8g84mk63r83	11	16	stem	stem	NOUN
8g84mk63r83	11	17	cells	cell	NOUN
8g84mk63r83	11	18	seeded	seed	VERB
8g84mk63r83	11	19	in	in	ADP
8g84mk63r83	11	20	high	high	ADJ
8g84mk63r83	11	21	density	density	NOUN
8g84mk63r83	11	22	pellet	pellet	NOUN
8g84mk63r83	11	23	culture	culture	NOUN
8g84mk63r83	11	24	or	or	CCONJ
8g84mk63r83	11	25	encapsulated	encapsulate	VERB
8g84mk63r83	11	26	in	in	ADP
8g84mk63r83	11	27	alginate	alginate	ADJ
8g84mk63r83	11	28	beads	bead	NOUN
8g84mk63r83	11	29	to	to	PART
8g84mk63r83	11	30	investigate	investigate	VERB
8g84mk63r83	11	31	the	the	DET
8g84mk63r83	11	32	potential	potential	NOUN
8g84mk63r83	11	33	for	for	ADP
8g84mk63r83	11	34	endochondral	endochondral	ADJ
8g84mk63r83	11	35	bone	bone	NOUN
8g84mk63r83	11	36	formation	formation	NOUN
8g84mk63r83	11	37	in	in	ADP
8g84mk63r83	11	38	a	a	DET
8g84mk63r83	11	39	clinically	clinically	ADV
8g84mk63r83	11	40	relevant	relevant	ADJ
8g84mk63r83	11	41	cell	cell	NOUN
8g84mk63r83	11	42	type	type	NOUN
8g84mk63r83	11	43	.	.	PUNCT
8g84mk63r83	12	1	despite	despite	SCONJ
8g84mk63r83	12	2	identical	identical	ADJ
8g84mk63r83	12	3	pre	pre	NOUN
8g84mk63r83	12	4	-	-	NOUN
8g84mk63r83	12	5	treatment	treatment	NOUN
8g84mk63r83	12	6	,	,	PUNCT
8g84mk63r83	12	7	the	the	DET
8g84mk63r83	12	8	culture	culture	NOUN
8g84mk63r83	12	9	systems	system	NOUN
8g84mk63r83	12	10	induced	induce	VERB
8g84mk63r83	12	11	significantly	significantly	ADV
8g84mk63r83	12	12	different	different	ADJ
8g84mk63r83	12	13	volumes	volume	NOUN
8g84mk63r83	12	14	of	of	ADP
8g84mk63r83	12	15	mineralized	mineralized	ADJ
8g84mk63r83	12	16	tissue	tissue	NOUN
8g84mk63r83	12	17	formation	formation	NOUN
8g84mk63r83	12	18	in	in	ADP
8g84mk63r83	12	19	vivo	vivo	PROPN
8g84mk63r83	12	20	.	.	PUNCT
8g84mk63r83	13	1	cell	cell	NOUN
8g84mk63r83	13	2	pellets	pellet	NOUN
8g84mk63r83	13	3	resulted	result	VERB
8g84mk63r83	13	4	in	in	ADP
8g84mk63r83	13	5	a	a	DET
8g84mk63r83	13	6	greater	great	ADJ
8g84mk63r83	13	7	amount	amount	NOUN
8g84mk63r83	13	8	of	of	ADP
8g84mk63r83	13	9	mineralized	mineralized	ADJ
8g84mk63r83	13	10	tissue	tissue	NOUN
8g84mk63r83	13	11	which	which	PRON
8g84mk63r83	13	12	accumulated	accumulate	VERB
8g84mk63r83	13	13	around	around	ADP
8g84mk63r83	13	14	a	a	DET
8g84mk63r83	13	15	large	large	ADJ
8g84mk63r83	13	16	volume	volume	NOUN
8g84mk63r83	13	17	exterior	exterior	NOUN
8g84mk63r83	13	18	to	to	ADP
8g84mk63r83	13	19	the	the	DET
8g84mk63r83	13	20	implants	implant	NOUN
8g84mk63r83	13	21	,	,	PUNCT
8g84mk63r83	13	22	while	while	SCONJ
8g84mk63r83	13	23	mineralized	mineralized	ADJ
8g84mk63r83	13	24	tissue	tissue	NOUN
8g84mk63r83	13	25	deposits	deposit	NOUN
8g84mk63r83	13	26	were	be	AUX
8g84mk63r83	13	27	confined	confine	VERB
8g84mk63r83	13	28	to	to	ADP
8g84mk63r83	13	29	a	a	DET
8g84mk63r83	13	30	smaller	small	ADJ
8g84mk63r83	13	31	volume	volume	NOUN
8g84mk63r83	13	32	in	in	ADP
8g84mk63r83	13	33	cell	cell	NOUN
8g84mk63r83	13	34	seeded	seed	VERB
8g84mk63r83	13	35	alginate	alginate	NOUN
8g84mk63r83	13	36	beads	bead	NOUN
8g84mk63r83	13	37	.	.	PUNCT
8g84mk63r83	14	1	these	these	DET
8g84mk63r83	14	2	findings	finding	NOUN
8g84mk63r83	14	3	further	far	ADV
8g84mk63r83	14	4	highlighted	highlight	VERB
8g84mk63r83	14	5	the	the	DET
8g84mk63r83	14	6	importance	importance	NOUN
8g84mk63r83	14	7	of	of	ADP
8g84mk63r83	14	8	pretreatment	pretreatment	NOUN
8g84mk63r83	14	9	and	and	CCONJ
8g84mk63r83	14	10	culture	culture	NOUN
8g84mk63r83	14	11	methods	method	NOUN
8g84mk63r83	14	12	with	with	ADP
8g84mk63r83	14	13	respect	respect	NOUN
8g84mk63r83	14	14	to	to	ADP
8g84mk63r83	14	15	the	the	PRON
8g84mk63r83	14	16	in	in	ADP
8g84mk63r83	14	17	vivo	vivo	ADJ
8g84mk63r83	14	18	response	response	NOUN
8g84mk63r83	14	19	induced	induce	VERB
8g84mk63r83	14	20	by	by	ADP
8g84mk63r83	14	21	tissue	tissue	NOUN
8g84mk63r83	14	22	engineered	engineer	VERB
8g84mk63r83	14	23	constructs	construct	NOUN
8g84mk63r83	14	24	.	.	PUNCT