id sid tid token lemma pos 7653708153k 1 1 people people NOUN 7653708153k 1 2 who who PRON 7653708153k 1 3 have have AUX 7653708153k 1 4 experienced experience VERB 7653708153k 1 5 early early ADJ 7653708153k 1 6 adversity adversity NOUN 7653708153k 1 7 ( ( PUNCT 7653708153k 1 8 ea ea NOUN 7653708153k 1 9 ) ) PUNCT 7653708153k 1 10 often often ADV 7653708153k 1 11 have have VERB 7653708153k 1 12 a a DET 7653708153k 1 13 more more ADV 7653708153k 1 14 severe severe ADJ 7653708153k 1 15 and and CCONJ 7653708153k 1 16 chronic chronic ADJ 7653708153k 1 17 course course NOUN 7653708153k 1 18 of of ADP 7653708153k 1 19 depression depression NOUN 7653708153k 1 20 compared compare VERB 7653708153k 1 21 to to ADP 7653708153k 1 22 those those PRON 7653708153k 1 23 who who PRON 7653708153k 1 24 never never ADV 7653708153k 1 25 experienced experience VERB 7653708153k 1 26 ea ea PROPN 7653708153k 1 27 . . PUNCT 7653708153k 2 1 the the DET 7653708153k 2 2 pernicious pernicious ADJ 7653708153k 2 3 depressive depressive ADJ 7653708153k 2 4 outcomes outcome NOUN 7653708153k 2 5 associated associate VERB 7653708153k 2 6 with with ADP 7653708153k 2 7 ea ea NOUN 7653708153k 2 8 have have AUX 7653708153k 2 9 prompted prompt VERB 7653708153k 2 10 research research NOUN 7653708153k 2 11 on on ADP 7653708153k 2 12 the the DET 7653708153k 2 13 possible possible ADJ 7653708153k 2 14 mechanisms mechanism NOUN 7653708153k 2 15 by by ADP 7653708153k 2 16 which which PRON 7653708153k 2 17 those those PRON 7653708153k 2 18 with with ADP 7653708153k 2 19 ea ea NOUN 7653708153k 2 20 develop develop VERB 7653708153k 2 21 such such DET 7653708153k 2 22 a a DET 7653708153k 2 23 difficult difficult ADJ 7653708153k 2 24 course course NOUN 7653708153k 2 25 . . PUNCT 7653708153k 3 1 one one NUM 7653708153k 3 2 potential potential ADJ 7653708153k 3 3 mechanism mechanism NOUN 7653708153k 3 4 involves involve VERB 7653708153k 3 5 the the DET 7653708153k 3 6 dysregulation dysregulation NOUN 7653708153k 3 7 of of ADP 7653708153k 3 8 a a DET 7653708153k 3 9 critical critical ADJ 7653708153k 3 10 component component NOUN 7653708153k 3 11 of of ADP 7653708153k 3 12 the the DET 7653708153k 3 13 internal internal ADJ 7653708153k 3 14 stress stress NOUN 7653708153k 3 15 response response NOUN 7653708153k 3 16 system system NOUN 7653708153k 3 17 , , PUNCT 7653708153k 3 18 the the DET 7653708153k 3 19 hypothalamic hypothalamic NOUN 7653708153k 3 20 - - PUNCT 7653708153k 3 21 pituitary pituitary ADJ 7653708153k 3 22 - - PUNCT 7653708153k 3 23 adrenal adrenal ADJ 7653708153k 3 24 ( ( PUNCT 7653708153k 3 25 hpa hpa PROPN 7653708153k 3 26 ) ) PUNCT 7653708153k 3 27 axis axis NOUN 7653708153k 3 28 . . PUNCT 7653708153k 4 1 preclinical preclinical ADJ 7653708153k 4 2 research research NOUN 7653708153k 4 3 with with ADP 7653708153k 4 4 non non ADJ 7653708153k 4 5 - - ADJ 7653708153k 4 6 human human ADJ 7653708153k 4 7 primates primate NOUN 7653708153k 4 8 and and CCONJ 7653708153k 4 9 rodents rodent NOUN 7653708153k 4 10 supports support VERB 7653708153k 4 11 that that SCONJ 7653708153k 4 12 the the DET 7653708153k 4 13 hpa hpa PROPN 7653708153k 4 14 system system NOUN 7653708153k 4 15 becomes become VERB 7653708153k 4 16 dysregulated dysregulate VERB 7653708153k 4 17 following follow VERB 7653708153k 4 18 ea ea NOUN 7653708153k 4 19 and and CCONJ 7653708153k 4 20 specific specific ADJ 7653708153k 4 21 symptoms symptom NOUN 7653708153k 4 22 indicative indicative ADJ 7653708153k 4 23 of of ADP 7653708153k 4 24 major major ADJ 7653708153k 4 25 depression depression NOUN 7653708153k 4 26 result result NOUN 7653708153k 4 27 . . PUNCT 7653708153k 5 1 parallel parallel NOUN 7653708153k 5 2 to to ADP 7653708153k 5 3 preclinical preclinical ADJ 7653708153k 5 4 evidence evidence NOUN 7653708153k 5 5 , , PUNCT 7653708153k 5 6 hpa hpa PROPN 7653708153k 5 7 dysregulation dysregulation PROPN 7653708153k 5 8 has have AUX 7653708153k 5 9 also also ADV 7653708153k 5 10 been be AUX 7653708153k 5 11 consistently consistently ADV 7653708153k 5 12 associated associate VERB 7653708153k 5 13 with with ADP 7653708153k 5 14 ea ea NOUN 7653708153k 5 15 and and CCONJ 7653708153k 5 16 depression depression NOUN 7653708153k 5 17 in in ADP 7653708153k 5 18 humans human NOUN 7653708153k 5 19 . . PUNCT 7653708153k 6 1 prolonged prolonged ADJ 7653708153k 6 2 hpa hpa PROPN 7653708153k 6 3 dysregulation dysregulation PROPN 7653708153k 6 4 may may AUX 7653708153k 6 5 influence influence VERB 7653708153k 6 6 the the DET 7653708153k 6 7 manifestation manifestation NOUN 7653708153k 6 8 of of ADP 7653708153k 6 9 certain certain ADJ 7653708153k 6 10 symptoms symptom NOUN 7653708153k 6 11 in in ADP 7653708153k 6 12 depressed depressed ADJ 7653708153k 6 13 individuals individual NOUN 7653708153k 6 14 with with ADP 7653708153k 6 15 ea ea PROPN 7653708153k 6 16 . . PUNCT 7653708153k 7 1 the the DET 7653708153k 7 2 present present ADJ 7653708153k 7 3 study study NOUN 7653708153k 7 4 seeks seek VERB 7653708153k 7 5 to to PART 7653708153k 7 6 extend extend VERB 7653708153k 7 7 this this DET 7653708153k 7 8 line line NOUN 7653708153k 7 9 of of ADP 7653708153k 7 10 research research NOUN 7653708153k 7 11 to to PART 7653708153k 7 12 evaluate evaluate VERB 7653708153k 7 13 whether whether SCONJ 7653708153k 7 14 ea ea NOUN 7653708153k 7 15 predicts predict VERB 7653708153k 7 16 specific specific ADJ 7653708153k 7 17 manifestations manifestation NOUN 7653708153k 7 18 of of ADP 7653708153k 7 19 depressive depressive ADJ 7653708153k 7 20 symptoms symptom NOUN 7653708153k 7 21 in in ADP 7653708153k 7 22 humans human NOUN 7653708153k 7 23 suffering suffer VERB 7653708153k 7 24 from from ADP 7653708153k 7 25 major major ADJ 7653708153k 7 26 depression depression NOUN 7653708153k 7 27 . . PUNCT