id	sid	tid	token	lemma	pos
5x21td98h32	1	1	amamistatins	amamistatin	VERB
5x21td98h32	1	2	a	a	PRON
5x21td98h32	1	3	and	and	CCONJ
5x21td98h32	1	4	b	b	NOUN
5x21td98h32	1	5	are	be	AUX
5x21td98h32	1	6	natural	natural	ADJ
5x21td98h32	1	7	products	product	NOUN
5x21td98h32	1	8	that	that	PRON
5x21td98h32	1	9	were	be	AUX
5x21td98h32	1	10	isolated	isolate	VERB
5x21td98h32	1	11	from	from	ADP
5x21td98h32	1	12	the	the	DET
5x21td98h32	1	13	actinomycete	actinomycete	ADJ
5x21td98h32	1	14	nocardia	nocardia	NOUN
5x21td98h32	1	15	asteroides	asteroide	NOUN
5x21td98h32	1	16	after	after	ADP
5x21td98h32	1	17	their	their	PRON
5x21td98h32	1	18	identification	identification	NOUN
5x21td98h32	1	19	during	during	ADP
5x21td98h32	1	20	a	a	DET
5x21td98h32	1	21	screen	screen	NOUN
5x21td98h32	1	22	for	for	ADP
5x21td98h32	1	23	growth	growth	NOUN
5x21td98h32	1	24	inhibitors	inhibitor	NOUN
5x21td98h32	1	25	of	of	ADP
5x21td98h32	1	26	human	human	ADJ
5x21td98h32	1	27	tumor	tumor	NOUN
5x21td98h32	1	28	cells	cell	NOUN
5x21td98h32	1	29	.	.	PUNCT
5x21td98h32	2	1	amamistatin	amamistatin	PROPN
5x21td98h32	2	2	a	a	PRON
5x21td98h32	2	3	was	be	AUX
5x21td98h32	2	4	found	find	VERB
5x21td98h32	2	5	to	to	PART
5x21td98h32	2	6	have	have	VERB
5x21td98h32	2	7	anti	anti	ADJ
5x21td98h32	2	8	-	-	ADJ
5x21td98h32	2	9	proliferative	proliferative	ADJ
5x21td98h32	2	10	effects	effect	NOUN
5x21td98h32	2	11	against	against	ADP
5x21td98h32	2	12	mcf-7	mcf-7	PRON
5x21td98h32	2	13	breast	breast	NOUN
5x21td98h32	2	14	,	,	PUNCT
5x21td98h32	2	15	a549	a549	PROPN
5x21td98h32	2	16	lung	lung	NOUN
5x21td98h32	2	17	,	,	PUNCT
5x21td98h32	2	18	and	and	CCONJ
5x21td98h32	2	19	mkn45	mkn45	ADJ
5x21td98h32	2	20	stomach	stomach	NOUN
5x21td98h32	2	21	tumor	tumor	NOUN
5x21td98h32	2	22	cell	cell	NOUN
5x21td98h32	2	23	lines	line	NOUN
5x21td98h32	2	24	(	(	PUNCT
5x21td98h32	2	25	ic50	ic50	PROPN
5x21td98h32	2	26	0.48	0.48	NUM
5x21td98h32	2	27	,	,	PUNCT
5x21td98h32	2	28	0.56	0.56	NUM
5x21td98h32	2	29	,	,	PUNCT
5x21td98h32	2	30	0.24	0.24	NUM
5x21td98h32	2	31	?	?	PUNCT
5x21td98h32	2	32	m	m	NOUN
5x21td98h32	2	33	,	,	PUNCT
5x21td98h32	2	34	respectively	respectively	ADV
5x21td98h32	2	35	)	)	PUNCT
5x21td98h32	2	36	.	.	PUNCT
5x21td98h32	3	1	both	both	DET
5x21td98h32	3	2	compounds	compound	NOUN
5x21td98h32	3	3	were	be	AUX
5x21td98h32	3	4	also	also	ADV
5x21td98h32	3	5	cytotoxic	cytotoxic	NOUN
5x21td98h32	3	6	to	to	ADP
5x21td98h32	3	7	p388	p388	PROPN
5x21td98h32	3	8	mouse	mouse	VERB
5x21td98h32	3	9	lymphocytic	lymphocytic	ADJ
5x21td98h32	3	10	leukemia	leukemia	NOUN
5x21td98h32	3	11	cells	cell	NOUN
5x21td98h32	3	12	(	(	PUNCT
5x21td98h32	3	13	ic50	ic50	PROPN
5x21td98h32	3	14	15	15	NUM
5x21td98h32	3	15	and	and	CCONJ
5x21td98h32	3	16	16	16	NUM
5x21td98h32	3	17	nm	nm	NOUN
5x21td98h32	3	18	)	)	PUNCT
5x21td98h32	3	19	.	.	PUNCT
5x21td98h32	4	1	amamistatins	amamistatin	NOUN
5x21td98h32	4	2	share	share	VERB
5x21td98h32	4	3	important	important	ADJ
5x21td98h32	4	4	structural	structural	ADJ
5x21td98h32	4	5	features	feature	NOUN
5x21td98h32	4	6	with	with	ADP
5x21td98h32	4	7	iron	iron	NOUN
5x21td98h32	4	8	-	-	PUNCT
5x21td98h32	4	9	binding	bind	VERB
5x21td98h32	4	10	mycobacterial	mycobacterial	ADJ
5x21td98h32	4	11	siderophores	siderophore	NOUN
5x21td98h32	4	12	(	(	PUNCT
5x21td98h32	4	13	mycobactins	mycobactin	NOUN
5x21td98h32	4	14	and	and	CCONJ
5x21td98h32	4	15	carboxymycobactins	carboxymycobactin	NOUN
5x21td98h32	4	16	)	)	PUNCT
5x21td98h32	4	17	and	and	CCONJ
5x21td98h32	4	18	retrohydroxamate	retrohydroxamate	NOUN
5x21td98h32	4	19	hdac	hdac	PROPN
5x21td98h32	4	20	inhibitors	inhibitor	NOUN
5x21td98h32	4	21	.	.	PUNCT
5x21td98h32	5	1	based	base	VERB
5x21td98h32	5	2	on	on	ADP
5x21td98h32	5	3	this	this	DET
5x21td98h32	5	4	structural	structural	ADJ
5x21td98h32	5	5	similarity	similarity	NOUN
5x21td98h32	5	6	,	,	PUNCT
5x21td98h32	5	7	two	two	NUM
5x21td98h32	5	8	possible	possible	ADJ
5x21td98h32	5	9	mechanisms	mechanism	NOUN
5x21td98h32	5	10	of	of	ADP
5x21td98h32	5	11	tumor	tumor	NOUN
5x21td98h32	5	12	cell	cell	NOUN
5x21td98h32	5	13	inhibition	inhibition	NOUN
5x21td98h32	5	14	were	be	AUX
5x21td98h32	5	15	proposed	propose	VERB
5x21td98h32	5	16	,	,	PUNCT
5x21td98h32	5	17	both	both	PRON
5x21td98h32	5	18	involving	involve	VERB
5x21td98h32	5	19	metal	metal	NOUN
5x21td98h32	5	20	binding	bind	VERB
5x21td98h32	5	21	.	.	PUNCT
5x21td98h32	6	1	in	in	ADP
5x21td98h32	6	2	order	order	NOUN
5x21td98h32	6	3	to	to	PART
5x21td98h32	6	4	probe	probe	VERB
5x21td98h32	6	5	the	the	DET
5x21td98h32	6	6	biological	biological	ADJ
5x21td98h32	6	7	activity	activity	NOUN
5x21td98h32	6	8	of	of	ADP
5x21td98h32	6	9	the	the	DET
5x21td98h32	6	10	amamistatin	amamistatin	PROPN
5x21td98h32	6	11	family	family	PROPN
5x21td98h32	6	12	,	,	PUNCT
5x21td98h32	6	13	synthetic	synthetic	ADJ
5x21td98h32	6	14	compounds	compound	NOUN
5x21td98h32	6	15	with	with	ADP
5x21td98h32	6	16	specific	specific	ADJ
5x21td98h32	6	17	structural	structural	ADJ
5x21td98h32	6	18	variations	variation	NOUN
5x21td98h32	6	19	were	be	AUX
5x21td98h32	6	20	needed	need	VERB
5x21td98h32	6	21	.	.	PUNCT
5x21td98h32	7	1	during	during	ADP
5x21td98h32	7	2	the	the	DET
5x21td98h32	7	3	course	course	NOUN
5x21td98h32	7	4	of	of	ADP
5x21td98h32	7	5	this	this	DET
5x21td98h32	7	6	work	work	NOUN
5x21td98h32	7	7	,	,	PUNCT
5x21td98h32	7	8	the	the	DET
5x21td98h32	7	9	total	total	ADJ
5x21td98h32	7	10	synthesis	synthesis	NOUN
5x21td98h32	7	11	of	of	ADP
5x21td98h32	7	12	amamistatin	amamistatin	PROPN
5x21td98h32	7	13	b	b	PROPN
5x21td98h32	7	14	was	be	AUX
5x21td98h32	7	15	completed	complete	VERB
5x21td98h32	7	16	,	,	PUNCT
5x21td98h32	7	17	along	along	ADP
5x21td98h32	7	18	with	with	ADP
5x21td98h32	7	19	the	the	DET
5x21td98h32	7	20	syntheses	synthesis	NOUN
5x21td98h32	7	21	of	of	ADP
5x21td98h32	7	22	a	a	DET
5x21td98h32	7	23	diastereomer	diastereomer	PROPN
5x21td98h32	7	24	of	of	ADP
5x21td98h32	7	25	amamistatin	amamistatin	PROPN
5x21td98h32	7	26	b	b	PROPN
5x21td98h32	7	27	and	and	CCONJ
5x21td98h32	7	28	a	a	DET
5x21td98h32	7	29	structural	structural	ADJ
5x21td98h32	7	30	variant	variant	NOUN
5x21td98h32	7	31	lacking	lack	VERB
5x21td98h32	7	32	two	two	NUM
5x21td98h32	7	33	metal	metal	NOUN
5x21td98h32	7	34	-	-	PUNCT
5x21td98h32	7	35	binding	bind	VERB
5x21td98h32	7	36	functionalities	functionality	NOUN
5x21td98h32	7	37	.	.	PUNCT
5x21td98h32	8	1	all	all	DET
5x21td98h32	8	2	three	three	NUM
5x21td98h32	8	3	compounds	compound	NOUN
5x21td98h32	8	4	,	,	PUNCT
5x21td98h32	8	5	along	along	ADP
5x21td98h32	8	6	with	with	ADP
5x21td98h32	8	7	synthetic	synthetic	ADJ
5x21td98h32	8	8	intermediates	intermediate	NOUN
5x21td98h32	8	9	,	,	PUNCT
5x21td98h32	8	10	were	be	AUX
5x21td98h32	8	11	screened	screen	VERB
5x21td98h32	8	12	in	in	ADP
5x21td98h32	8	13	several	several	ADJ
5x21td98h32	8	14	assays	assay	NOUN
5x21td98h32	8	15	to	to	PART
5x21td98h32	8	16	study	study	VERB
5x21td98h32	8	17	their	their	PRON
5x21td98h32	8	18	effect	effect	NOUN
5x21td98h32	8	19	on	on	ADP
5x21td98h32	8	20	the	the	DET
5x21td98h32	8	21	growth	growth	NOUN
5x21td98h32	8	22	of	of	ADP
5x21td98h32	8	23	tumor	tumor	NOUN
5x21td98h32	8	24	cells	cell	NOUN
5x21td98h32	8	25	and	and	CCONJ
5x21td98h32	8	26	m.	m.	NOUN
5x21td98h32	8	27	tuberculosis	tuberculosis	NOUN
5x21td98h32	8	28	,	,	PUNCT
5x21td98h32	8	29	as	as	ADV
5x21td98h32	8	30	well	well	ADV
5x21td98h32	8	31	as	as	ADP
5x21td98h32	8	32	their	their	PRON
5x21td98h32	8	33	ability	ability	NOUN
5x21td98h32	8	34	to	to	PART
5x21td98h32	8	35	inhibit	inhibit	VERB
5x21td98h32	8	36	hdac	hdac	PROPN
5x21td98h32	8	37	.	.	PUNCT
5x21td98h32	9	1	amamisatin	amamisatin	PROPN
5x21td98h32	9	2	b	b	PROPN
5x21td98h32	9	3	strongly	strongly	ADV
5x21td98h32	9	4	inhibited	inhibit	VERB
5x21td98h32	9	5	the	the	DET
5x21td98h32	9	6	growth	growth	NOUN
5x21td98h32	9	7	of	of	ADP
5x21td98h32	9	8	m.	m.	NOUN
5x21td98h32	9	9	tuberculosis	tuberculosis	NOUN
5x21td98h32	9	10	h37rv	h37rv	NOUN
5x21td98h32	9	11	at	at	ADP
5x21td98h32	9	12	high	high	ADJ
5x21td98h32	9	13	concentrations	concentration	NOUN
5x21td98h32	9	14	,	,	PUNCT
5x21td98h32	9	15	but	but	CCONJ
5x21td98h32	9	16	acted	act	VERB
5x21td98h32	9	17	as	as	ADP
5x21td98h32	9	18	a	a	DET
5x21td98h32	9	19	growth	growth	NOUN
5x21td98h32	9	20	promoter	promoter	NOUN
5x21td98h32	9	21	of	of	ADP
5x21td98h32	9	22	m.	m.	NOUN
5x21td98h32	9	23	smegmatis	smegmatis	PROPN
5x21td98h32	9	24	and	and	CCONJ
5x21td98h32	9	25	other	other	ADJ
5x21td98h32	9	26	bacteria	bacteria	NOUN
5x21td98h32	9	27	.	.	PUNCT
5x21td98h32	10	1	synthetic	synthetic	ADJ
5x21td98h32	10	2	analogs	analog	NOUN
5x21td98h32	10	3	and	and	CCONJ
5x21td98h32	10	4	intermediates	intermediate	NOUN
5x21td98h32	10	5	were	be	AUX
5x21td98h32	10	6	largely	largely	ADV
5x21td98h32	10	7	ineffective	ineffective	ADJ
5x21td98h32	10	8	at	at	ADP
5x21td98h32	10	9	inhibiting	inhibit	VERB
5x21td98h32	10	10	mycobacterial	mycobacterial	ADJ
5x21td98h32	10	11	growth	growth	NOUN
5x21td98h32	10	12	.	.	PUNCT
5x21td98h32	11	1	smaller	small	ADJ
5x21td98h32	11	2	amamistatin	amamistatin	NOUN
5x21td98h32	11	3	precursors	precursor	NOUN
5x21td98h32	11	4	displayed	display	VERB
5x21td98h32	11	5	varying	varying	ADJ
5x21td98h32	11	6	levels	level	NOUN
5x21td98h32	11	7	of	of	ADP
5x21td98h32	11	8	inhibition	inhibition	NOUN
5x21td98h32	11	9	against	against	ADP
5x21td98h32	11	10	both	both	CCONJ
5x21td98h32	11	11	the	the	DET
5x21td98h32	11	12	hdac	hdac	PROPN
5x21td98h32	11	13	enzyme	enzyme	NOUN
5x21td98h32	11	14	and	and	CCONJ
5x21td98h32	11	15	two	two	NUM
5x21td98h32	11	16	human	human	ADJ
5x21td98h32	11	17	tumor	tumor	NOUN
5x21td98h32	11	18	cell	cell	NOUN
5x21td98h32	11	19	lines	line	NOUN
5x21td98h32	11	20	(	(	PUNCT
5x21td98h32	11	21	mcf-7	mcf-7	ADP
5x21td98h32	11	22	and	and	CCONJ
5x21td98h32	11	23	pc-3	pc-3	NOUN
5x21td98h32	11	24	)	)	PUNCT
5x21td98h32	11	25	,	,	PUNCT
5x21td98h32	11	26	but	but	CCONJ
5x21td98h32	11	27	hdac	hdac	PROPN
5x21td98h32	11	28	activity	activity	NOUN
5x21td98h32	11	29	was	be	AUX
5x21td98h32	11	30	not	not	PART
5x21td98h32	11	31	retained	retain	VERB
5x21td98h32	11	32	by	by	ADP
5x21td98h32	11	33	the	the	DET
5x21td98h32	11	34	larger	large	ADJ
5x21td98h32	11	35	amamistatin	amamistatin	PROPN
5x21td98h32	11	36	compounds	compounds	PROPN
5x21td98h32	11	37	.	.	PUNCT
5x21td98h32	12	1	amamistatin	amamistatin	PROPN
5x21td98h32	12	2	b	b	PROPN
5x21td98h32	12	3	was	be	AUX
5x21td98h32	12	4	,	,	PUNCT
5x21td98h32	12	5	however	however	ADV
5x21td98h32	12	6	,	,	PUNCT
5x21td98h32	12	7	an	an	DET
5x21td98h32	12	8	extremely	extremely	ADV
5x21td98h32	12	9	effective	effective	ADJ
5x21td98h32	12	10	growth	growth	NOUN
5x21td98h32	12	11	inhibitor	inhibitor	NOUN
5x21td98h32	12	12	of	of	ADP
5x21td98h32	12	13	mcf-7	mcf-7	PRON
5x21td98h32	12	14	breast	breast	NOUN
5x21td98h32	12	15	cancer	cancer	NOUN
5x21td98h32	12	16	cells	cell	NOUN
5x21td98h32	12	17	,	,	PUNCT
5x21td98h32	12	18	with	with	ADP
5x21td98h32	12	19	an	an	DET
5x21td98h32	12	20	ic50	ic50	PROPN
5x21td98h32	12	21	of	of	ADP
5x21td98h32	12	22	120	120	NUM
5x21td98h32	12	23	nm	nm	NOUN
5x21td98h32	12	24	.	.	PUNCT
5x21td98h32	13	1	the	the	DET
5x21td98h32	13	2	lower	low	ADJ
5x21td98h32	13	3	level	level	NOUN
5x21td98h32	13	4	of	of	ADP
5x21td98h32	13	5	activity	activity	NOUN
5x21td98h32	13	6	displayed	display	VERB
5x21td98h32	13	7	by	by	ADP
5x21td98h32	13	8	the	the	DET
5x21td98h32	13	9	synthetic	synthetic	ADJ
5x21td98h32	13	10	analog	analog	NOUN
5x21td98h32	13	11	with	with	ADP
5x21td98h32	13	12	reduced	reduce	VERB
5x21td98h32	13	13	metal	metal	NOUN
5x21td98h32	13	14	-	-	PUNCT
5x21td98h32	13	15	binding	bind	VERB
5x21td98h32	13	16	ability	ability	NOUN
5x21td98h32	13	17	supports	support	VERB
5x21td98h32	13	18	the	the	DET
5x21td98h32	13	19	hypothesis	hypothesis	NOUN
5x21td98h32	13	20	that	that	SCONJ
5x21td98h32	13	21	the	the	DET
5x21td98h32	13	22	anti	anti	ADJ
5x21td98h32	13	23	-	-	ADJ
5x21td98h32	13	24	tumor	tumor	ADJ
5x21td98h32	13	25	activity	activity	NOUN
5x21td98h32	13	26	of	of	ADP
5x21td98h32	13	27	amamistatin	amamistatin	PROPN
5x21td98h32	13	28	b	b	PROPN
5x21td98h32	13	29	is	be	AUX
5x21td98h32	13	30	related	relate	VERB
5x21td98h32	13	31	to	to	ADP
5x21td98h32	13	32	iron	iron	NOUN
5x21td98h32	13	33	chelation	chelation	NOUN
5x21td98h32	13	34	.	.	PUNCT