id sid tid token lemma pos 4x51hh66t0w 1 1 while while SCONJ 4x51hh66t0w 1 2 the the DET 4x51hh66t0w 1 3 framework framework NOUN 4x51hh66t0w 1 4 for for ADP 4x51hh66t0w 1 5 cytosolic cytosolic NOUN 4x51hh66t0w 1 6 delivery delivery NOUN 4x51hh66t0w 1 7 has have AUX 4x51hh66t0w 1 8 been be AUX 4x51hh66t0w 1 9 well well ADV 4x51hh66t0w 1 10 established establish VERB 4x51hh66t0w 1 11 , , PUNCT 4x51hh66t0w 1 12 there there PRON 4x51hh66t0w 1 13 is be VERB 4x51hh66t0w 1 14 a a DET 4x51hh66t0w 1 15 need need NOUN 4x51hh66t0w 1 16 to to PART 4x51hh66t0w 1 17 develop develop VERB 4x51hh66t0w 1 18 new new ADJ 4x51hh66t0w 1 19 ways way NOUN 4x51hh66t0w 1 20 to to PART 4x51hh66t0w 1 21 enhance enhance VERB 4x51hh66t0w 1 22 cell cell NOUN 4x51hh66t0w 1 23 permeation permeation NOUN 4x51hh66t0w 1 24 and and CCONJ 4x51hh66t0w 1 25 intracellular intracellular ADJ 4x51hh66t0w 1 26 targeting targeting NOUN 4x51hh66t0w 1 27 of of ADP 4x51hh66t0w 1 28 drugs drug NOUN 4x51hh66t0w 1 29 and and CCONJ 4x51hh66t0w 1 30 imaging image VERB 4x51hh66t0w 1 31 agents agent NOUN 4x51hh66t0w 1 32 . . PUNCT 4x51hh66t0w 2 1 theranostics theranostic NOUN 4x51hh66t0w 2 2 , , PUNCT 4x51hh66t0w 2 3 which which PRON 4x51hh66t0w 2 4 combines combine VERB 4x51hh66t0w 2 5 these these DET 4x51hh66t0w 2 6 features feature NOUN 4x51hh66t0w 2 7 into into ADP 4x51hh66t0w 2 8 one one NUM 4x51hh66t0w 2 9 system system NOUN 4x51hh66t0w 2 10 , , PUNCT 4x51hh66t0w 2 11 needs need VERB 4x51hh66t0w 2 12 new new ADJ 4x51hh66t0w 2 13 molecular molecular ADJ 4x51hh66t0w 2 14 strategies strategy NOUN 4x51hh66t0w 2 15 to to PART 4x51hh66t0w 2 16 overcome overcome VERB 4x51hh66t0w 2 17 undesirable undesirable ADJ 4x51hh66t0w 2 18 differences difference NOUN 4x51hh66t0w 2 19 in in ADP 4x51hh66t0w 2 20 biodistribution biodistribution NOUN 4x51hh66t0w 2 21 and and CCONJ 4x51hh66t0w 2 22 selectivity selectivity NOUN 4x51hh66t0w 2 23 that that PRON 4x51hh66t0w 2 24 currently currently ADV 4x51hh66t0w 2 25 exist exist VERB 4x51hh66t0w 2 26 between between ADP 4x51hh66t0w 2 27 distinct distinct ADJ 4x51hh66t0w 2 28 therapeutic therapeutic ADJ 4x51hh66t0w 2 29 and and CCONJ 4x51hh66t0w 2 30 diagnostic diagnostic ADJ 4x51hh66t0w 2 31 agents.this agents.this DET 4x51hh66t0w 2 32 thesis thesis NOUN 4x51hh66t0w 2 33 investigates investigate VERB 4x51hh66t0w 2 34 different different ADJ 4x51hh66t0w 2 35 supramolecular supramolecular ADJ 4x51hh66t0w 2 36 methods method NOUN 4x51hh66t0w 2 37 to to PART 4x51hh66t0w 2 38 deliver deliver VERB 4x51hh66t0w 2 39 fluorescent fluorescent ADJ 4x51hh66t0w 2 40 payloads payload NOUN 4x51hh66t0w 2 41 into into ADP 4x51hh66t0w 2 42 the the DET 4x51hh66t0w 2 43 cell cell NOUN 4x51hh66t0w 2 44 including include VERB 4x51hh66t0w 2 45 the the DET 4x51hh66t0w 2 46 use use NOUN 4x51hh66t0w 2 47 of of ADP 4x51hh66t0w 2 48 nanoparticle nanoparticle NOUN 4x51hh66t0w 2 49 delivery delivery NOUN 4x51hh66t0w 2 50 systems system NOUN 4x51hh66t0w 2 51 and and CCONJ 4x51hh66t0w 2 52 small small ADJ 4x51hh66t0w 2 53 molecule molecule NOUN 4x51hh66t0w 2 54 imaging image VERB 4x51hh66t0w 2 55 agents agent NOUN 4x51hh66t0w 2 56 . . PUNCT 4x51hh66t0w 3 1 specifically specifically ADV 4x51hh66t0w 3 2 , , PUNCT 4x51hh66t0w 3 3 chapter chapter NOUN 4x51hh66t0w 3 4 2 2 NUM 4x51hh66t0w 3 5 evaluates evaluate VERB 4x51hh66t0w 3 6 the the DET 4x51hh66t0w 3 7 supramolecular supramolecular ADJ 4x51hh66t0w 3 8 properties property NOUN 4x51hh66t0w 3 9 of of ADP 4x51hh66t0w 3 10 a a DET 4x51hh66t0w 3 11 new new ADJ 4x51hh66t0w 3 12 family family NOUN 4x51hh66t0w 3 13 of of ADP 4x51hh66t0w 3 14 water water NOUN 4x51hh66t0w 3 15 - - PUNCT 4x51hh66t0w 3 16 soluble soluble ADJ 4x51hh66t0w 3 17 hyperbranched hyperbranche VERB 4x51hh66t0w 3 18 polytriazoles polytriazole NOUN 4x51hh66t0w 3 19 that that PRON 4x51hh66t0w 3 20 have have VERB 4x51hh66t0w 3 21 a a DET 4x51hh66t0w 3 22 unique unique ADJ 4x51hh66t0w 3 23 unimolecular unimolecular ADJ 4x51hh66t0w 3 24 micelle micelle PROPN 4x51hh66t0w 3 25 structure structure NOUN 4x51hh66t0w 3 26 that that PRON 4x51hh66t0w 3 27 could could AUX 4x51hh66t0w 3 28 be be AUX 4x51hh66t0w 3 29 broadly broadly ADV 4x51hh66t0w 3 30 useful useful ADJ 4x51hh66t0w 3 31 as as ADP 4x51hh66t0w 3 32 a a DET 4x51hh66t0w 3 33 nanocarrier nanocarrier NOUN 4x51hh66t0w 3 34 for for ADP 4x51hh66t0w 3 35 various various ADJ 4x51hh66t0w 3 36 applications application NOUN 4x51hh66t0w 3 37 in in ADP 4x51hh66t0w 3 38 therapy therapy NOUN 4x51hh66t0w 3 39 , , PUNCT 4x51hh66t0w 3 40 imaging imaging NOUN 4x51hh66t0w 3 41 , , PUNCT 4x51hh66t0w 3 42 or or CCONJ 4x51hh66t0w 3 43 a a DET 4x51hh66t0w 3 44 combination combination NOUN 4x51hh66t0w 3 45 of of ADP 4x51hh66t0w 3 46 the the DET 4x51hh66t0w 3 47 two two NUM 4x51hh66t0w 3 48 . . PUNCT 4x51hh66t0w 4 1 chapter chapter NOUN 4x51hh66t0w 4 2 3 3 NUM 4x51hh66t0w 4 3 describes describe VERB 4x51hh66t0w 4 4 fundamental fundamental ADJ 4x51hh66t0w 4 5 studies study NOUN 4x51hh66t0w 4 6 of of ADP 4x51hh66t0w 4 7 four four NUM 4x51hh66t0w 4 8 liposome liposome NOUN 4x51hh66t0w 4 9 systems system NOUN 4x51hh66t0w 4 10 that that PRON 4x51hh66t0w 4 11 explored explore VERB 4x51hh66t0w 4 12 different different ADJ 4x51hh66t0w 4 13 supramolecular supramolecular ADJ 4x51hh66t0w 4 14 strategies strategy NOUN 4x51hh66t0w 4 15 for for ADP 4x51hh66t0w 4 16 targeted targeted ADJ 4x51hh66t0w 4 17 liposome liposome NOUN 4x51hh66t0w 4 18 delivery delivery NOUN 4x51hh66t0w 4 19 and and CCONJ 4x51hh66t0w 4 20 fusion fusion NOUN 4x51hh66t0w 4 21 , , PUNCT 4x51hh66t0w 4 22 liposome liposome NOUN 4x51hh66t0w 4 23 leakage leakage NOUN 4x51hh66t0w 4 24 , , PUNCT 4x51hh66t0w 4 25 and and CCONJ 4x51hh66t0w 4 26 chemically chemically ADV 4x51hh66t0w 4 27 triggered trigger VERB 4x51hh66t0w 4 28 membrane membrane NOUN 4x51hh66t0w 4 29 fusion fusion NOUN 4x51hh66t0w 4 30 . . PUNCT 4x51hh66t0w 5 1 much much ADJ 4x51hh66t0w 5 2 of of ADP 4x51hh66t0w 5 3 this this DET 4x51hh66t0w 5 4 work work NOUN 4x51hh66t0w 5 5 employs employ VERB 4x51hh66t0w 5 6 synthavidin synthavidin NOUN 4x51hh66t0w 5 7 technology technology NOUN 4x51hh66t0w 5 8 , , PUNCT 4x51hh66t0w 5 9 which which PRON 4x51hh66t0w 5 10 is be AUX 4x51hh66t0w 5 11 based base VERB 4x51hh66t0w 5 12 on on ADP 4x51hh66t0w 5 13 the the DET 4x51hh66t0w 5 14 supramolecular supramolecular ADJ 4x51hh66t0w 5 15 capture capture NOUN 4x51hh66t0w 5 16 of of ADP 4x51hh66t0w 5 17 deep deep ADJ 4x51hh66t0w 5 18 - - PUNCT 4x51hh66t0w 5 19 red red ADJ 4x51hh66t0w 5 20 fluorescent fluorescent NOUN 4x51hh66t0w 5 21 squaraine squaraine ADJ 4x51hh66t0w 5 22 dyes dye NOUN 4x51hh66t0w 5 23 by by ADP 4x51hh66t0w 5 24 tetralactam tetralactam NOUN 4x51hh66t0w 5 25 macrocycles macrocycle NOUN 4x51hh66t0w 5 26 . . PUNCT 4x51hh66t0w 6 1 subsequent subsequent ADJ 4x51hh66t0w 6 2 chapters chapter NOUN 4x51hh66t0w 6 3 focus focus VERB 4x51hh66t0w 6 4 on on ADP 4x51hh66t0w 6 5 microscopy microscopy NOUN 4x51hh66t0w 6 6 using use VERB 4x51hh66t0w 6 7 small small ADJ 4x51hh66t0w 6 8 molecule molecule NOUN 4x51hh66t0w 6 9 fluorescent fluorescent NOUN 4x51hh66t0w 6 10 probes probe NOUN 4x51hh66t0w 6 11 . . PUNCT 4x51hh66t0w 7 1 in in ADP 4x51hh66t0w 7 2 chapter chapter NOUN 4x51hh66t0w 7 3 4 4 NUM 4x51hh66t0w 7 4 , , PUNCT 4x51hh66t0w 7 5 an an DET 4x51hh66t0w 7 6 intracellular intracellular ADJ 4x51hh66t0w 7 7 fluorescence fluorescence ADJ 4x51hh66t0w 7 8 competition competition NOUN 4x51hh66t0w 7 9 assay assay NOUN 4x51hh66t0w 7 10 is be AUX 4x51hh66t0w 7 11 developed develop VERB 4x51hh66t0w 7 12 to to PART 4x51hh66t0w 7 13 assess assess VERB 4x51hh66t0w 7 14 the the DET 4x51hh66t0w 7 15 capability capability NOUN 4x51hh66t0w 7 16 of of ADP 4x51hh66t0w 7 17 inhibitor inhibitor NOUN 4x51hh66t0w 7 18 candidate candidate NOUN 4x51hh66t0w 7 19 molecules molecule NOUN 4x51hh66t0w 7 20 to to PART 4x51hh66t0w 7 21 engage engage VERB 4x51hh66t0w 7 22 the the DET 4x51hh66t0w 7 23 biomedically biomedically ADV 4x51hh66t0w 7 24 important important ADJ 4x51hh66t0w 7 25 enzyme enzyme NOUN 4x51hh66t0w 7 26 histone histone NOUN 4x51hh66t0w 7 27 deacetylase deacetylase NOUN 4x51hh66t0w 7 28 6 6 NUM 4x51hh66t0w 7 29 ( ( PUNCT 4x51hh66t0w 7 30 hdac6 hdac6 PROPN 4x51hh66t0w 7 31 ) ) PUNCT 4x51hh66t0w 7 32 inside inside ADP 4x51hh66t0w 7 33 living living NOUN 4x51hh66t0w 7 34 cells cell NOUN 4x51hh66t0w 7 35 . . PUNCT 4x51hh66t0w 8 1 the the DET 4x51hh66t0w 8 2 assay assay PROPN 4x51hh66t0w 8 3 uses use VERB 4x51hh66t0w 8 4 fluorescence fluorescence ADJ 4x51hh66t0w 8 5 cell cell NOUN 4x51hh66t0w 8 6 microscopy microscopy NOUN 4x51hh66t0w 8 7 and and CCONJ 4x51hh66t0w 8 8 flow flow VERB 4x51hh66t0w 8 9 cytometry cytometry NOUN 4x51hh66t0w 8 10 to to PART 4x51hh66t0w 8 11 quantify quantify VERB 4x51hh66t0w 8 12 cell cell NOUN 4x51hh66t0w 8 13 staining stain VERB 4x51hh66t0w 8 14 by by ADP 4x51hh66t0w 8 15 a a DET 4x51hh66t0w 8 16 hdac hdac PROPN 4x51hh66t0w 8 17 - - PUNCT 4x51hh66t0w 8 18 selective selective ADJ 4x51hh66t0w 8 19 fluorescent fluorescent NOUN 4x51hh66t0w 8 20 probe probe NOUN 4x51hh66t0w 8 21 . . PUNCT 4x51hh66t0w 9 1 in in ADP 4x51hh66t0w 9 2 chapter chapter NOUN 4x51hh66t0w 9 3 5 5 NUM 4x51hh66t0w 9 4 , , PUNCT 4x51hh66t0w 9 5 two two NUM 4x51hh66t0w 9 6 structurally structurally ADV 4x51hh66t0w 9 7 related relate VERB 4x51hh66t0w 9 8 deep deep ADJ 4x51hh66t0w 9 9 - - PUNCT 4x51hh66t0w 9 10 red red ADJ 4x51hh66t0w 9 11 fluorescent fluorescent NOUN 4x51hh66t0w 9 12 probes probe NOUN 4x51hh66t0w 9 13 are be AUX 4x51hh66t0w 9 14 evaluated evaluate VERB 4x51hh66t0w 9 15 for for ADP 4x51hh66t0w 9 16 microscopic microscopic ADJ 4x51hh66t0w 9 17 imaging imaging NOUN 4x51hh66t0w 9 18 . . PUNCT 4x51hh66t0w 10 1 one one NUM 4x51hh66t0w 10 2 of of ADP 4x51hh66t0w 10 3 the the DET 4x51hh66t0w 10 4 probes probe NOUN 4x51hh66t0w 10 5 is be AUX 4x51hh66t0w 10 6 a a DET 4x51hh66t0w 10 7 targeted target VERB 4x51hh66t0w 10 8 fluorescent fluorescent NOUN 4x51hh66t0w 10 9 molecule molecule NOUN 4x51hh66t0w 10 10 with with ADP 4x51hh66t0w 10 11 appended append VERB 4x51hh66t0w 10 12 ni ni ADJ 4x51hh66t0w 10 13 - - PUNCT 4x51hh66t0w 10 14 nitrilotriacetate nitrilotriacetate PROPN 4x51hh66t0w 10 15 groups group NOUN 4x51hh66t0w 10 16 that that PRON 4x51hh66t0w 10 17 provided provide VERB 4x51hh66t0w 10 18 affinity affinity NOUN 4x51hh66t0w 10 19 for for ADP 4x51hh66t0w 10 20 histidine histidine NOUN 4x51hh66t0w 10 21 - - PUNCT 4x51hh66t0w 10 22 tagged tag VERB 4x51hh66t0w 10 23 proteins protein NOUN 4x51hh66t0w 10 24 . . PUNCT 4x51hh66t0w 11 1 the the DET 4x51hh66t0w 11 2 other other ADJ 4x51hh66t0w 11 3 probe probe NOUN 4x51hh66t0w 11 4 is be AUX 4x51hh66t0w 11 5 equipped equip VERB 4x51hh66t0w 11 6 with with ADP 4x51hh66t0w 11 7 polyarginine polyarginine NOUN 4x51hh66t0w 11 8 peptide peptide NOUN 4x51hh66t0w 11 9 that that PRON 4x51hh66t0w 11 10 improve improve VERB 4x51hh66t0w 11 11 cellular cellular ADJ 4x51hh66t0w 11 12 uptake uptake NOUN 4x51hh66t0w 11 13 . . PUNCT 4x51hh66t0w 12 1 together together ADV 4x51hh66t0w 12 2 , , PUNCT 4x51hh66t0w 12 3 these these DET 4x51hh66t0w 12 4 projects project NOUN 4x51hh66t0w 12 5 represent represent VERB 4x51hh66t0w 12 6 a a DET 4x51hh66t0w 12 7 new new ADJ 4x51hh66t0w 12 8 approach approach NOUN 4x51hh66t0w 12 9 to to ADP 4x51hh66t0w 12 10 intracellular intracellular ADJ 4x51hh66t0w 12 11 microscopy microscopy NOUN 4x51hh66t0w 12 12 using use VERB 4x51hh66t0w 12 13 targeted target VERB 4x51hh66t0w 12 14 deep deep ADJ 4x51hh66t0w 12 15 - - PUNCT 4x51hh66t0w 12 16 red red ADJ 4x51hh66t0w 12 17 fluorescent fluorescent NOUN 4x51hh66t0w 12 18 probes probe NOUN 4x51hh66t0w 12 19 . . PUNCT