id sid tid token lemma pos 41687h16573 1 1 bone bone NOUN 41687h16573 1 2 , , PUNCT 41687h16573 1 3 is be AUX 41687h16573 1 4 a a DET 41687h16573 1 5 dynamic dynamic ADJ 41687h16573 1 6 tissue tissue NOUN 41687h16573 1 7 that that PRON 41687h16573 1 8 is be AUX 41687h16573 1 9 continually continually ADV 41687h16573 1 10 being be AUX 41687h16573 1 11 renewed renew VERB 41687h16573 1 12 at at ADP 41687h16573 1 13 a a DET 41687h16573 1 14 rate rate NOUN 41687h16573 1 15 dependent dependent ADJ 41687h16573 1 16 on on ADP 41687h16573 1 17 the the DET 41687h16573 1 18 health health NOUN 41687h16573 1 19 of of ADP 41687h16573 1 20 its its PRON 41687h16573 1 21 cells cell NOUN 41687h16573 1 22 , , PUNCT 41687h16573 1 23 which which PRON 41687h16573 1 24 is be AUX 41687h16573 1 25 linked link VERB 41687h16573 1 26 to to ADP 41687h16573 1 27 nutrient nutrient ADJ 41687h16573 1 28 availability availability NOUN 41687h16573 1 29 and and CCONJ 41687h16573 1 30 other other ADJ 41687h16573 1 31 incompletely incompletely ADV 41687h16573 1 32 understood understand VERB 41687h16573 1 33 factors factor NOUN 41687h16573 1 34 . . PUNCT 41687h16573 2 1 it it PRON 41687h16573 2 2 is be AUX 41687h16573 2 3 known know VERB 41687h16573 2 4 that that SCONJ 41687h16573 2 5 weight weight NOUN 41687h16573 2 6 - - PUNCT 41687h16573 2 7 bearing bear VERB 41687h16573 2 8 exercise exercise NOUN 41687h16573 2 9 can can AUX 41687h16573 2 10 noticeably noticeably ADV 41687h16573 2 11 affect affect VERB 41687h16573 2 12 bone bone NOUN 41687h16573 2 13 density density NOUN 41687h16573 2 14 and and CCONJ 41687h16573 2 15 has have AUX 41687h16573 2 16 been be AUX 41687h16573 2 17 hypothesized hypothesize VERB 41687h16573 2 18 as as ADP 41687h16573 2 19 a a DET 41687h16573 2 20 mechanism mechanism NOUN 41687h16573 2 21 for for ADP 41687h16573 2 22 increased increase VERB 41687h16573 2 23 nutrient nutrient NOUN 41687h16573 2 24 delivery delivery NOUN 41687h16573 2 25 in in ADP 41687h16573 2 26 bone bone NOUN 41687h16573 2 27 . . PUNCT 41687h16573 3 1 to to ADP 41687h16573 3 2 date date NOUN 41687h16573 3 3 the the DET 41687h16573 3 4 only only ADJ 41687h16573 3 5 model model NOUN 41687h16573 3 6 for for ADP 41687h16573 3 7 mass mass ADJ 41687h16573 3 8 transport transport NOUN 41687h16573 3 9 in in ADP 41687h16573 3 10 bone bone NOUN 41687h16573 3 11 is be AUX 41687h16573 3 12 passive passive ADJ 41687h16573 3 13 diffusion diffusion NOUN 41687h16573 3 14 , , PUNCT 41687h16573 3 15 which which PRON 41687h16573 3 16 insufficiently insufficiently ADV 41687h16573 3 17 meets meet VERB 41687h16573 3 18 bone bone NOUN 41687h16573 3 19 cell cell NOUN 41687h16573 3 20 metabolic metabolic NOUN 41687h16573 3 21 requirements requirement NOUN 41687h16573 3 22 and and CCONJ 41687h16573 3 23 is be AUX 41687h16573 3 24 independent independent ADJ 41687h16573 3 25 of of ADP 41687h16573 3 26 mechanical mechanical ADJ 41687h16573 3 27 stress stress NOUN 41687h16573 3 28 . . PUNCT 41687h16573 4 1 the the DET 41687h16573 4 2 objective objective NOUN 41687h16573 4 3 of of ADP 41687h16573 4 4 this this DET 41687h16573 4 5 research research NOUN 41687h16573 4 6 was be AUX 41687h16573 4 7 to to AUX 41687h16573 4 8 : : PUNCT 41687h16573 4 9 1 1 X 41687h16573 4 10 ) ) PUNCT 41687h16573 4 11 propose propose VERB 41687h16573 4 12 a a DET 41687h16573 4 13 theoretical theoretical ADJ 41687h16573 4 14 model model NOUN 41687h16573 4 15 for for ADP 41687h16573 4 16 enhanced enhanced ADJ 41687h16573 4 17 mass mass ADJ 41687h16573 4 18 transport transport NOUN 41687h16573 4 19 in in ADP 41687h16573 4 20 cortical cortical ADJ 41687h16573 4 21 bone bone NOUN 41687h16573 4 22 due due ADP 41687h16573 4 23 to to ADP 41687h16573 4 24 shearing shear VERB 41687h16573 4 25 oscillatory oscillatory ADJ 41687h16573 4 26 fluid fluid NOUN 41687h16573 4 27 flow flow NOUN 41687h16573 4 28 dependent dependent ADJ 41687h16573 4 29 on on ADP 41687h16573 4 30 molecular molecular ADJ 41687h16573 4 31 size size NOUN 41687h16573 4 32 , , PUNCT 41687h16573 4 33 strain strain NOUN 41687h16573 4 34 magnitude magnitude NOUN 41687h16573 4 35 , , PUNCT 41687h16573 4 36 and and CCONJ 41687h16573 4 37 frequency frequency NOUN 41687h16573 4 38 ; ; PUNCT 41687h16573 4 39 2 2 X 41687h16573 4 40 ) ) PUNCT 41687h16573 4 41 demonstrate demonstrate VERB 41687h16573 4 42 experimentally experimentally ADV 41687h16573 4 43 that that SCONJ 41687h16573 4 44 oscillating oscillate VERB 41687h16573 4 45 fluid fluid NOUN 41687h16573 4 46 flows flow NOUN 41687h16573 4 47 affect affect VERB 41687h16573 4 48 the the DET 41687h16573 4 49 mass mass ADJ 41687h16573 4 50 transport transport NOUN 41687h16573 4 51 of of ADP 41687h16573 4 52 particles particle NOUN 41687h16573 4 53 in in ADP 41687h16573 4 54 sheep sheep NOUN 41687h16573 4 55 cortical cortical ADJ 41687h16573 4 56 bone bone NOUN 41687h16573 4 57 ; ; PUNCT 41687h16573 4 58 3 3 X 41687h16573 4 59 ) ) PUNCT 41687h16573 4 60 prove prove VERB 41687h16573 4 61 that that SCONJ 41687h16573 4 62 increased increase VERB 41687h16573 4 63 nutrient nutrient NOUN 41687h16573 4 64 levels level NOUN 41687h16573 4 65 influence influence NOUN 41687h16573 4 66 bone bone NOUN 41687h16573 4 67 cell cell NOUN 41687h16573 4 68 osteogenesis osteogenesis NOUN 41687h16573 4 69 and and CCONJ 41687h16573 4 70 metabolism metabolism NOUN 41687h16573 4 71 in in ADP 41687h16573 4 72 - - PUNCT 41687h16573 4 73 vitro vitro X 41687h16573 4 74 ; ; PUNCT 41687h16573 4 75 4 4 X 41687h16573 4 76 ) ) PUNCT 41687h16573 4 77 develop develop VERB 41687h16573 4 78 calcium calcium NOUN 41687h16573 4 79 phosphate phosphate NOUN 41687h16573 4 80 nano nano NOUN 41687h16573 4 81 - - PUNCT 41687h16573 4 82 carriers carrier NOUN 41687h16573 4 83 for for ADP 41687h16573 4 84 nutrients nutrient NOUN 41687h16573 4 85 and and CCONJ 41687h16573 4 86 drugs drug NOUN 41687h16573 4 87 deliverable deliverable ADJ 41687h16573 4 88 through through ADP 41687h16573 4 89 the the DET 41687h16573 4 90 new new ADJ 41687h16573 4 91 mechanism mechanism NOUN 41687h16573 4 92 . . PUNCT 41687h16573 5 1 the the DET 41687h16573 5 2 theoretical theoretical ADJ 41687h16573 5 3 model model NOUN 41687h16573 5 4 predicted predict VERB 41687h16573 5 5 transport transport NOUN 41687h16573 5 6 enhancements enhancement NOUN 41687h16573 5 7 of of ADP 41687h16573 5 8 up up ADP 41687h16573 5 9 to to PART 41687h16573 5 10 100 100 NUM 41687h16573 5 11 fold fold NOUN 41687h16573 5 12 for for ADP 41687h16573 5 13 molecules molecule NOUN 41687h16573 5 14 larger large ADJ 41687h16573 5 15 than than ADP 41687h16573 5 16 7 7 NUM 41687h16573 5 17 nm nm NOUN 41687h16573 5 18 in in ADP 41687h16573 5 19 diameter diameter NOUN 41687h16573 5 20 . . PUNCT 41687h16573 6 1 in in ADP 41687h16573 6 2 sheep sheep NOUN 41687h16573 6 3 cortical cortical ADJ 41687h16573 6 4 bone bone NOUN 41687h16573 6 5 , , PUNCT 41687h16573 6 6 for for ADP 41687h16573 6 7 20 20 NUM 41687h16573 6 8 and and CCONJ 41687h16573 6 9 40 40 NUM 41687h16573 6 10 nm nm NOUN 41687h16573 6 11 sized sized ADJ 41687h16573 6 12 solutes solute NOUN 41687h16573 6 13 , , PUNCT 41687h16573 6 14 for for ADP 41687h16573 6 15 frequencies frequency NOUN 41687h16573 6 16 of of ADP 41687h16573 6 17 1 1 NUM 41687h16573 6 18 - - SYM 41687h16573 6 19 3 3 NUM 41687h16573 6 20 hz hz NOUN 41687h16573 6 21 and and CCONJ 41687h16573 6 22 20 20 NUM 41687h16573 6 23 khz khz NOUN 41687h16573 6 24 , , PUNCT 41687h16573 6 25 experimental experimental ADJ 41687h16573 6 26 diffusivity diffusivity NOUN 41687h16573 6 27 enhancements enhancement NOUN 41687h16573 6 28 of of ADP 41687h16573 6 29 respectively respectively ADV 41687h16573 6 30 40 40 NUM 41687h16573 6 31 - - SYM 41687h16573 6 32 550 550 NUM 41687h16573 6 33 and and CCONJ 41687h16573 6 34 150 150 NUM 41687h16573 6 35 were be AUX 41687h16573 6 36 observed observe VERB 41687h16573 6 37 , , PUNCT 41687h16573 6 38 in in ADP 41687h16573 6 39 accordance accordance NOUN 41687h16573 6 40 with with ADP 41687h16573 6 41 model model NOUN 41687h16573 6 42 predictions prediction NOUN 41687h16573 6 43 . . PUNCT 41687h16573 7 1 the the DET 41687h16573 7 2 rate rate NOUN 41687h16573 7 3 of of ADP 41687h16573 7 4 bone bone NOUN 41687h16573 7 5 deposition deposition NOUN 41687h16573 7 6 , , PUNCT 41687h16573 7 7 related relate VERB 41687h16573 7 8 to to ADP 41687h16573 7 9 nutrient nutrient NOUN 41687h16573 7 10 level level NOUN 41687h16573 7 11 by by ADP 41687h16573 7 12 michaelis michaelis PROPN 41687h16573 7 13 - - PUNCT 41687h16573 7 14 menten menten PROPN 41687h16573 7 15 kinetics kinetic NOUN 41687h16573 7 16 for for ADP 41687h16573 7 17 human human ADJ 41687h16573 7 18 fetal fetal ADJ 41687h16573 7 19 osteoblast osteoblast NOUN 41687h16573 7 20 , , PUNCT 41687h16573 7 21 was be AUX 41687h16573 7 22 measured measure VERB 41687h16573 7 23 by by ADP 41687h16573 7 24 in in ADP 41687h16573 7 25 - - PUNCT 41687h16573 7 26 vitro vitro X 41687h16573 7 27 experiments experiment NOUN 41687h16573 7 28 , , PUNCT 41687h16573 7 29 which which PRON 41687h16573 7 30 showed show VERB 41687h16573 7 31 that that SCONJ 41687h16573 7 32 if if SCONJ 41687h16573 7 33 passive passive ADJ 41687h16573 7 34 diffusion diffusion NOUN 41687h16573 7 35 in in ADP 41687h16573 7 36 bone bone NOUN 41687h16573 7 37 was be AUX 41687h16573 7 38 increased increase VERB 41687h16573 7 39 by by ADP 41687h16573 7 40 1000 1000 NUM 41687h16573 7 41 using use VERB 41687h16573 7 42 oscillatory oscillatory ADJ 41687h16573 7 43 flow flow NOUN 41687h16573 7 44 mechanisms mechanism NOUN 41687h16573 7 45 , , PUNCT 41687h16573 7 46 then then ADV 41687h16573 7 47 kinetic kinetic NOUN 41687h16573 7 48 and and CCONJ 41687h16573 7 49 diffusional diffusional ADJ 41687h16573 7 50 rates rate NOUN 41687h16573 7 51 would would AUX 41687h16573 7 52 be be AUX 41687h16573 7 53 equal equal ADJ 41687h16573 7 54 , , PUNCT 41687h16573 7 55 and and CCONJ 41687h16573 7 56 bone bone NOUN 41687h16573 7 57 deposition deposition NOUN 41687h16573 7 58 would would AUX 41687h16573 7 59 be be AUX 41687h16573 7 60 an an DET 41687h16573 7 61 ideally ideally ADV 41687h16573 7 62 tuned tune VERB 41687h16573 7 63 biological biological ADJ 41687h16573 7 64 transformation transformation NOUN 41687h16573 7 65 . . PUNCT 41687h16573 8 1 in in ADP 41687h16573 8 2 addition addition NOUN 41687h16573 8 3 , , PUNCT 41687h16573 8 4 in in ADP 41687h16573 8 5 - - PUNCT 41687h16573 8 6 vitro vitro X 41687h16573 8 7 experiments experiment NOUN 41687h16573 8 8 showed show VERB 41687h16573 8 9 that that SCONJ 41687h16573 8 10 bone bone NOUN 41687h16573 8 11 cell cell NOUN 41687h16573 8 12 osteogenesis osteogenesis NOUN 41687h16573 8 13 was be AUX 41687h16573 8 14 affected affect VERB 41687h16573 8 15 by by ADP 41687h16573 8 16 core core ADJ 41687h16573 8 17 - - PUNCT 41687h16573 8 18 shell shell ADJ 41687h16573 8 19 and and CCONJ 41687h16573 8 20 mesoporous mesoporous ADJ 41687h16573 8 21 calcium calcium NOUN 41687h16573 8 22 phosphate phosphate NOUN 41687h16573 8 23 nano nano PROPN 41687h16573 8 24 - - PUNCT 41687h16573 8 25 carriers carrier NOUN 41687h16573 8 26 . . PUNCT 41687h16573 9 1 the the DET 41687h16573 9 2 transport transport NOUN 41687h16573 9 3 of of ADP 41687h16573 9 4 these these DET 41687h16573 9 5 carriers carrier NOUN 41687h16573 9 6 in in ADP 41687h16573 9 7 bone bone NOUN 41687h16573 9 8 was be AUX 41687h16573 9 9 theoretically theoretically ADV 41687h16573 9 10 predicted predict VERB 41687h16573 9 11 by by ADP 41687h16573 9 12 the the DET 41687h16573 9 13 model model NOUN 41687h16573 9 14 . . PUNCT 41687h16573 10 1 in in ADP 41687h16573 10 2 conclusion conclusion NOUN 41687h16573 10 3 , , PUNCT 41687h16573 10 4 a a DET 41687h16573 10 5 new new ADJ 41687h16573 10 6 model model NOUN 41687h16573 10 7 describing describe VERB 41687h16573 10 8 oscillatory oscillatory ADJ 41687h16573 10 9 fluid fluid ADJ 41687h16573 10 10 shear shear NOUN 41687h16573 10 11 - - PUNCT 41687h16573 10 12 effects effect NOUN 41687h16573 10 13 can can AUX 41687h16573 10 14 enhance enhance VERB 41687h16573 10 15 solute solute ADJ 41687h16573 10 16 transport transport NOUN 41687h16573 10 17 in in ADP 41687h16573 10 18 cortical cortical ADJ 41687h16573 10 19 and and CCONJ 41687h16573 10 20 osteoporotic osteoporotic ADJ 41687h16573 10 21 bone bone NOUN 41687h16573 10 22 by by ADP 41687h16573 10 23 repetitive repetitive ADJ 41687h16573 10 24 strains strain NOUN 41687h16573 10 25 generated generate VERB 41687h16573 10 26 during during ADP 41687h16573 10 27 physical physical ADJ 41687h16573 10 28 activity activity NOUN 41687h16573 10 29 and and CCONJ 41687h16573 10 30 acoustic acoustic ADJ 41687h16573 10 31 healing healing NOUN 41687h16573 10 32 . . PUNCT 41687h16573 11 1 the the DET 41687h16573 11 2 model model NOUN 41687h16573 11 3 gives give VERB 41687h16573 11 4 new new ADJ 41687h16573 11 5 insights insight NOUN 41687h16573 11 6 into into ADP 41687h16573 11 7 the the DET 41687h16573 11 8 mechanisms mechanism NOUN 41687h16573 11 9 behind behind ADP 41687h16573 11 10 bone bone NOUN 41687h16573 11 11 functional functional ADJ 41687h16573 11 12 adaptation adaptation NOUN 41687h16573 11 13 and and CCONJ 41687h16573 11 14 is be AUX 41687h16573 11 15 the the DET 41687h16573 11 16 basis basis NOUN 41687h16573 11 17 for for ADP 41687h16573 11 18 a a DET 41687h16573 11 19 strain strain NOUN 41687h16573 11 20 - - PUNCT 41687h16573 11 21 based base VERB 41687h16573 11 22 therapy therapy NOUN 41687h16573 11 23 involving involve VERB 41687h16573 11 24 bioactive bioactive ADJ 41687h16573 11 25 " " PUNCT 41687h16573 11 26 smart smart ADJ 41687h16573 11 27 ' ' PUNCT 41687h16573 11 28 osteoconductive osteoconductive ADJ 41687h16573 11 29 nano nano NOUN 41687h16573 11 30 - - PUNCT 41687h16573 11 31 device device NOUN 41687h16573 11 32 . . PUNCT