id	sid	tid	token	lemma	pos
3t945q49p7h	1	1	with	with	ADP
3t945q49p7h	1	2	our	our	PRON
3t945q49p7h	1	3	current	current	ADJ
3t945q49p7h	1	4	antibiotic	antibiotic	ADJ
3t945q49p7h	1	5	arsenal	arsenal	NOUN
3t945q49p7h	1	6	dwindling	dwindle	VERB
3t945q49p7h	1	7	,	,	PUNCT
3t945q49p7h	1	8	the	the	DET
3t945q49p7h	1	9	need	need	NOUN
3t945q49p7h	1	10	for	for	ADP
3t945q49p7h	1	11	new	new	ADJ
3t945q49p7h	1	12	antibiotics	antibiotic	NOUN
3t945q49p7h	1	13	with	with	ADP
3t945q49p7h	1	14	novel	novel	ADJ
3t945q49p7h	1	15	mechanisms	mechanism	NOUN
3t945q49p7h	1	16	is	be	AUX
3t945q49p7h	1	17	needed	need	VERB
3t945q49p7h	1	18	.	.	PUNCT
3t945q49p7h	2	1	described	describe	VERB
3t945q49p7h	2	2	herein	herein	ADV
3t945q49p7h	2	3	are	be	AUX
3t945q49p7h	2	4	the	the	DET
3t945q49p7h	2	5	syntheses	synthesis	NOUN
3t945q49p7h	2	6	of	of	ADP
3t945q49p7h	2	7	sets	set	NOUN
3t945q49p7h	2	8	of	of	ADP
3t945q49p7h	2	9	hydroxamate	hydroxamate	NOUN
3t945q49p7h	2	10	containing	contain	VERB
3t945q49p7h	2	11	monobactams	monobactam	NOUN
3t945q49p7h	2	12	,	,	PUNCT
3t945q49p7h	2	13	bicyclic	bicyclic	NOUN
3t945q49p7h	2	14	β	β	NOUN
3t945q49p7h	2	15	-	-	PUNCT
3t945q49p7h	2	16	lactams	lactams	NOUN
3t945q49p7h	2	17	,	,	PUNCT
3t945q49p7h	2	18	and	and	CCONJ
3t945q49p7h	2	19	cephalosporins	cephalosporin	NOUN
3t945q49p7h	2	20	in	in	ADP
3t945q49p7h	2	21	addition	addition	NOUN
3t945q49p7h	2	22	to	to	ADP
3t945q49p7h	2	23	their	their	PRON
3t945q49p7h	2	24	biological	biological	ADJ
3t945q49p7h	2	25	evaluations.chapter	evaluations.chapter	NOUN
3t945q49p7h	2	26	1	1	NUM
3t945q49p7h	2	27	provides	provide	VERB
3t945q49p7h	2	28	a	a	DET
3t945q49p7h	2	29	general	general	ADJ
3t945q49p7h	2	30	introduction	introduction	NOUN
3t945q49p7h	2	31	to	to	ADP
3t945q49p7h	2	32	antibiotics	antibiotic	NOUN
3t945q49p7h	2	33	and	and	CCONJ
3t945q49p7h	2	34	the	the	DET
3t945q49p7h	2	35	β	β	PROPN
3t945q49p7h	2	36	-	-	PUNCT
3t945q49p7h	2	37	lactam	lactam	NOUN
3t945q49p7h	2	38	family	family	NOUN
3t945q49p7h	2	39	with	with	ADP
3t945q49p7h	2	40	an	an	DET
3t945q49p7h	2	41	emphasis	emphasis	NOUN
3t945q49p7h	2	42	on	on	ADP
3t945q49p7h	2	43	utilizing	utilize	VERB
3t945q49p7h	2	44	the	the	DET
3t945q49p7h	2	45	β	β	PROPN
3t945q49p7h	2	46	-	-	PUNCT
3t945q49p7h	2	47	lactam	lactam	NOUN
3t945q49p7h	2	48	core	core	NOUN
3t945q49p7h	2	49	for	for	ADP
3t945q49p7h	2	50	delivery	delivery	NOUN
3t945q49p7h	2	51	of	of	ADP
3t945q49p7h	2	52	medicinal	medicinal	ADJ
3t945q49p7h	2	53	agents	agent	NOUN
3t945q49p7h	2	54	.	.	PUNCT
3t945q49p7h	3	1	the	the	DET
3t945q49p7h	3	2	chapter	chapter	NOUN
3t945q49p7h	3	3	then	then	ADV
3t945q49p7h	3	4	concludes	conclude	VERB
3t945q49p7h	3	5	with	with	ADP
3t945q49p7h	3	6	a	a	DET
3t945q49p7h	3	7	preview	preview	NOUN
3t945q49p7h	3	8	of	of	ADP
3t945q49p7h	3	9	the	the	DET
3t945q49p7h	3	10	present	present	ADJ
3t945q49p7h	3	11	work	work	NOUN
3t945q49p7h	3	12	in	in	ADP
3t945q49p7h	3	13	addition	addition	NOUN
3t945q49p7h	3	14	to	to	ADP
3t945q49p7h	3	15	key	key	ADJ
3t945q49p7h	3	16	literature	literature	NOUN
3t945q49p7h	3	17	precedent	precedent	NOUN
3t945q49p7h	3	18	.	.	PUNCT
3t945q49p7h	4	1	chapters	chapter	NOUN
3t945q49p7h	4	2	2	2	NUM
3t945q49p7h	4	3	-	-	SYM
3t945q49p7h	4	4	4	4	NUM
3t945q49p7h	4	5	detail	detail	NOUN
3t945q49p7h	4	6	studies	study	NOUN
3t945q49p7h	4	7	on	on	ADP
3t945q49p7h	4	8	the	the	DET
3t945q49p7h	4	9	syntheses	synthesis	NOUN
3t945q49p7h	4	10	of	of	ADP
3t945q49p7h	4	11	monobactams	monobactam	NOUN
3t945q49p7h	4	12	,	,	PUNCT
3t945q49p7h	4	13	bicyclic	bicyclic	NOUN
3t945q49p7h	4	14	hydroxamate	hydroxamate	NOUN
3t945q49p7h	4	15	containing	contain	VERB
3t945q49p7h	4	16	β	β	NOUN
3t945q49p7h	4	17	-	-	PUNCT
3t945q49p7h	4	18	lactams	lactams	NOUN
3t945q49p7h	4	19	,	,	PUNCT
3t945q49p7h	4	20	and	and	CCONJ
3t945q49p7h	4	21	cephalosporins	cephalosporin	NOUN
3t945q49p7h	4	22	bearing	bear	VERB
3t945q49p7h	4	23	hydroxamate	hydroxamate	ADJ
3t945q49p7h	4	24	functionality	functionality	NOUN
3t945q49p7h	4	25	.	.	PUNCT
3t945q49p7h	5	1	as	as	SCONJ
3t945q49p7h	5	2	reported	report	VERB
3t945q49p7h	5	3	,	,	PUNCT
3t945q49p7h	5	4	a	a	DET
3t945q49p7h	5	5	number	number	NOUN
3t945q49p7h	5	6	of	of	ADP
3t945q49p7h	5	7	compounds	compound	NOUN
3t945q49p7h	5	8	exhibited	exhibit	VERB
3t945q49p7h	5	9	notable	notable	ADJ
3t945q49p7h	5	10	antibacterial	antibacterial	ADJ
3t945q49p7h	5	11	activity	activity	NOUN
3t945q49p7h	5	12	and/or	and/or	CCONJ
3t945q49p7h	5	13	β	β	PRON
3t945q49p7h	5	14	-	-	PUNCT
3t945q49p7h	5	15	lactamase	lactamase	ADJ
3t945q49p7h	5	16	inhibitory	inhibitory	ADJ
3t945q49p7h	5	17	activity	activity	NOUN
3t945q49p7h	5	18	.	.	PUNCT
3t945q49p7h	6	1	chapter	chapter	NOUN
3t945q49p7h	6	2	5	5	NUM
3t945q49p7h	6	3	discusses	discuss	VERB
3t945q49p7h	6	4	the	the	DET
3t945q49p7h	6	5	synthesis	synthesis	NOUN
3t945q49p7h	6	6	of	of	ADP
3t945q49p7h	6	7	hydroxamate	hydroxamate	NOUN
3t945q49p7h	6	8	containing	contain	VERB
3t945q49p7h	6	9	β	β	X
3t945q49p7h	6	10	-	-	PUNCT
3t945q49p7h	6	11	lactam	lactam	NOUN
3t945q49p7h	6	12	systems	system	NOUN
3t945q49p7h	6	13	bearing	bear	VERB
3t945q49p7h	6	14	an	an	DET
3t945q49p7h	6	15	alkylthio	alkylthio	NOUN
3t945q49p7h	6	16	linkage	linkage	NOUN
3t945q49p7h	6	17	between	between	ADP
3t945q49p7h	6	18	hydroxamate	hydroxamate	ADJ
3t945q49p7h	6	19	and	and	CCONJ
3t945q49p7h	6	20	β	β	NOUN
3t945q49p7h	6	21	-	-	NOUN
3t945q49p7h	6	22	lactam	lactam	NOUN
3t945q49p7h	6	23	.	.	PUNCT
3t945q49p7h	7	1	chapter	chapter	NOUN
3t945q49p7h	7	2	6	6	NUM
3t945q49p7h	7	3	presents	present	VERB
3t945q49p7h	7	4	the	the	DET
3t945q49p7h	7	5	syntheses	synthesis	NOUN
3t945q49p7h	7	6	of	of	ADP
3t945q49p7h	7	7	an	an	DET
3t945q49p7h	7	8	intriguing	intriguing	ADJ
3t945q49p7h	7	9	library	library	NOUN
3t945q49p7h	7	10	of	of	ADP
3t945q49p7h	7	11	hydroxamate	hydroxamate	ADJ
3t945q49p7h	7	12	containing	contain	VERB
3t945q49p7h	7	13	,	,	PUNCT
3t945q49p7h	7	14	n	n	ADV
3t945q49p7h	7	15	-	-	PUNCT
3t945q49p7h	7	16	methylthiolated	methylthiolate	VERB
3t945q49p7h	7	17	monobactams	monobactam	NOUN
3t945q49p7h	7	18	.	.	PUNCT
3t945q49p7h	8	1	a	a	DET
3t945q49p7h	8	2	number	number	NOUN
3t945q49p7h	8	3	of	of	ADP
3t945q49p7h	8	4	compounds	compound	NOUN
3t945q49p7h	8	5	exhibited	exhibit	VERB
3t945q49p7h	8	6	significant	significant	ADJ
3t945q49p7h	8	7	anti	anti	ADJ
3t945q49p7h	8	8	-	-	ADJ
3t945q49p7h	8	9	tb	tb	ADJ
3t945q49p7h	8	10	and	and	CCONJ
3t945q49p7h	8	11	β	β	PROPN
3t945q49p7h	8	12	-	-	PUNCT
3t945q49p7h	8	13	lactamase	lactamase	ADJ
3t945q49p7h	8	14	inhibitory	inhibitory	ADJ
3t945q49p7h	8	15	activity	activity	NOUN
3t945q49p7h	8	16	,	,	PUNCT
3t945q49p7h	8	17	with	with	ADP
3t945q49p7h	8	18	mic	mic	ADJ
3t945q49p7h	8	19	values	value	NOUN
3t945q49p7h	8	20	in	in	ADP
3t945q49p7h	8	21	the	the	DET
3t945q49p7h	8	22	range	range	NOUN
3t945q49p7h	8	23	of	of	ADP
3t945q49p7h	8	24	25	25	NUM
3t945q49p7h	8	25	to	to	ADP
3t945q49p7h	8	26	&	&	CCONJ
3t945q49p7h	8	27	lt;0.19	lt;0.19	X
3t945q49p7h	8	28	μm	μm	VERB
3t945q49p7h	8	29	against	against	ADP
3t945q49p7h	8	30	tb	tb	PROPN
3t945q49p7h	8	31	,	,	PUNCT
3t945q49p7h	8	32	and	and	CCONJ
3t945q49p7h	8	33	ki	ki	PROPN
3t945q49p7h	8	34	values	value	NOUN
3t945q49p7h	8	35	in	in	ADP
3t945q49p7h	8	36	the	the	DET
3t945q49p7h	8	37	range	range	NOUN
3t945q49p7h	8	38	of	of	ADP
3t945q49p7h	8	39	25	25	NUM
3t945q49p7h	8	40	-	-	SYM
3t945q49p7h	8	41	0.03	0.03	NUM
3t945q49p7h	8	42	μm	μm	NOUN
3t945q49p7h	8	43	against	against	ADP
3t945q49p7h	8	44	purified	purify	VERB
3t945q49p7h	8	45	ndm-1	ndm-1	ADP
3t945q49p7h	8	46	and	and	CCONJ
3t945q49p7h	8	47	vim-1	vim-1	PUNCT
3t945q49p7h	8	48	lysate	lysate	VERB
3t945q49p7h	8	49	metallo	metallo	NOUN
3t945q49p7h	8	50	β	β	PROPN
3t945q49p7h	8	51	-	-	PUNCT
3t945q49p7h	8	52	lactamases	lactamases	PROPN
3t945q49p7h	8	53	.	.	PUNCT
3t945q49p7h	9	1	chapter	chapter	NOUN
3t945q49p7h	9	2	7	7	NUM
3t945q49p7h	9	3	then	then	ADV
3t945q49p7h	9	4	focuses	focus	VERB
3t945q49p7h	9	5	on	on	ADP
3t945q49p7h	9	6	the	the	DET
3t945q49p7h	9	7	syntheses	synthesis	NOUN
3t945q49p7h	9	8	and	and	CCONJ
3t945q49p7h	9	9	biological	biological	ADJ
3t945q49p7h	9	10	evaluations	evaluation	NOUN
3t945q49p7h	9	11	of	of	ADP
3t945q49p7h	9	12	penicillins	penicillin	NOUN
3t945q49p7h	9	13	and	and	CCONJ
3t945q49p7h	9	14	cephalosporins	cephalosporin	NOUN
3t945q49p7h	9	15	possessing	possess	VERB
3t945q49p7h	9	16	o	o	ADJ
3t945q49p7h	9	17	-	-	ADJ
3t945q49p7h	9	18	substituted	substitute	VERB
3t945q49p7h	9	19	hydroxamates	hydroxamate	NOUN
3t945q49p7h	9	20	as	as	ADP
3t945q49p7h	9	21	alternative	alternative	ADJ
3t945q49p7h	9	22	"	"	PUNCT
3t945q49p7h	9	23	ionizable	ionizable	ADJ
3t945q49p7h	9	24	"	"	PUNCT
3t945q49p7h	9	25	groups	group	NOUN
3t945q49p7h	9	26	in	in	ADP
3t945q49p7h	9	27	place	place	NOUN
3t945q49p7h	9	28	for	for	ADP
3t945q49p7h	9	29	the	the	DET
3t945q49p7h	9	30	carboxylate	carboxylate	NOUN
3t945q49p7h	9	31	.	.	PUNCT
3t945q49p7h	10	1	many	many	ADJ
3t945q49p7h	10	2	of	of	ADP
3t945q49p7h	10	3	these	these	DET
3t945q49p7h	10	4	compounds	compound	NOUN
3t945q49p7h	10	5	have	have	VERB
3t945q49p7h	10	6	potent	potent	ADJ
3t945q49p7h	10	7	activity	activity	NOUN
3t945q49p7h	10	8	against	against	ADP
3t945q49p7h	10	9	a	a	DET
3t945q49p7h	10	10	variety	variety	NOUN
3t945q49p7h	10	11	of	of	ADP
3t945q49p7h	10	12	gram	gram	NOUN
3t945q49p7h	10	13	-	-	PUNCT
3t945q49p7h	10	14	positive	positive	ADJ
3t945q49p7h	10	15	bacteria	bacteria	NOUN
3t945q49p7h	10	16	.	.	PUNCT
3t945q49p7h	11	1	lastly	lastly	ADV
3t945q49p7h	11	2	,	,	PUNCT
3t945q49p7h	11	3	chapter	chapter	NOUN
3t945q49p7h	11	4	8	8	NUM
3t945q49p7h	11	5	discusses	discuss	VERB
3t945q49p7h	11	6	the	the	DET
3t945q49p7h	11	7	design	design	NOUN
3t945q49p7h	11	8	,	,	PUNCT
3t945q49p7h	11	9	syntheses	synthesis	NOUN
3t945q49p7h	11	10	,	,	PUNCT
3t945q49p7h	11	11	and	and	CCONJ
3t945q49p7h	11	12	anti	anti	ADJ
3t945q49p7h	11	13	-	-	ADJ
3t945q49p7h	11	14	tuberculosis	tuberculosis	ADJ
3t945q49p7h	11	15	activities	activity	NOUN
3t945q49p7h	11	16	for	for	ADP
3t945q49p7h	11	17	a	a	DET
3t945q49p7h	11	18	number	number	NOUN
3t945q49p7h	11	19	of	of	ADP
3t945q49p7h	11	20	cephalosproin	cephalosproin	NOUN
3t945q49p7h	11	21	-	-	PUNCT
3t945q49p7h	11	22	pbtz	pbtz	NOUN
3t945q49p7h	11	23	conjugates	conjugate	NOUN
3t945q49p7h	11	24	.	.	PUNCT
3t945q49p7h	12	1	these	these	DET
3t945q49p7h	12	2	conjugates	conjugate	NOUN
3t945q49p7h	12	3	showed	show	VERB
3t945q49p7h	12	4	notable	notable	ADJ
3t945q49p7h	12	5	anti	anti	ADJ
3t945q49p7h	12	6	-	-	ADJ
3t945q49p7h	12	7	tuberculosis	tuberculosis	ADJ
3t945q49p7h	12	8	activity	activity	NOUN
3t945q49p7h	12	9	with	with	ADP
3t945q49p7h	12	10	mic	mic	ADJ
3t945q49p7h	12	11	values	value	NOUN
3t945q49p7h	12	12	in	in	ADP
3t945q49p7h	12	13	the	the	DET
3t945q49p7h	12	14	range	range	NOUN
3t945q49p7h	12	15	of	of	ADP
3t945q49p7h	12	16	4.6	4.6	NUM
3t945q49p7h	12	17	to	to	PART
3t945q49p7h	12	18	1.5	1.5	NUM
3t945q49p7h	12	19	μm	μm	NOUN
3t945q49p7h	12	20	.	.	PUNCT