id sid tid token lemma pos 3b59183375t 1 1 the the DET 3b59183375t 1 2 natriuretic natriuretic ADJ 3b59183375t 1 3 peptide peptide NOUN 3b59183375t 1 4 ( ( PUNCT 3b59183375t 1 5 np np PROPN 3b59183375t 1 6 ) ) PUNCT 3b59183375t 1 7 system system NOUN 3b59183375t 1 8 is be AUX 3b59183375t 1 9 a a DET 3b59183375t 1 10 remarkably remarkably ADV 3b59183375t 1 11 efficacious efficacious ADJ 3b59183375t 1 12 hypotensive hypotensive NOUN 3b59183375t 1 13 , , PUNCT 3b59183375t 1 14 antihypertrophic antihypertrophic ADJ 3b59183375t 1 15 cardiovascular cardiovascular ADJ 3b59183375t 1 16 hormone hormone NOUN 3b59183375t 1 17 and and CCONJ 3b59183375t 1 18 receptor receptor NOUN 3b59183375t 1 19 family family NOUN 3b59183375t 1 20 . . PUNCT 3b59183375t 2 1 comparative comparative ADJ 3b59183375t 2 2 empirical empirical ADJ 3b59183375t 2 3 research research NOUN 3b59183375t 2 4 of of ADP 3b59183375t 2 5 the the DET 3b59183375t 2 6 np np PROPN 3b59183375t 2 7 system system NOUN 3b59183375t 2 8 in in ADP 3b59183375t 2 9 fish fish NOUN 3b59183375t 2 10 has have AUX 3b59183375t 2 11 yielded yield VERB 3b59183375t 2 12 two two NUM 3b59183375t 2 13 prominent prominent ADJ 3b59183375t 2 14 theories theory NOUN 3b59183375t 2 15 , , PUNCT 3b59183375t 2 16 the the DET 3b59183375t 2 17 osmoregulatory osmoregulatory NOUN 3b59183375t 2 18 and and CCONJ 3b59183375t 2 19 cardioprotective cardioprotective ADJ 3b59183375t 2 20 hypotheses hypothesis NOUN 3b59183375t 2 21 . . PUNCT 3b59183375t 3 1 the the DET 3b59183375t 3 2 osmoregulatory osmoregulatory ADJ 3b59183375t 3 3 hypothesis hypothesis NOUN 3b59183375t 3 4 is be AUX 3b59183375t 3 5 based base VERB 3b59183375t 3 6 largely largely ADV 3b59183375t 3 7 on on ADP 3b59183375t 3 8 physiological physiological ADJ 3b59183375t 3 9 actions action NOUN 3b59183375t 3 10 and and CCONJ 3b59183375t 3 11 stimuli stimulus NOUN 3b59183375t 3 12 of of ADP 3b59183375t 3 13 the the DET 3b59183375t 3 14 np np PROPN 3b59183375t 3 15 system system NOUN 3b59183375t 3 16 in in ADP 3b59183375t 3 17 the the DET 3b59183375t 3 18 eel eel NOUN 3b59183375t 3 19 , , PUNCT 3b59183375t 3 20 and and CCONJ 3b59183375t 3 21 implies imply VERB 3b59183375t 3 22 that that SCONJ 3b59183375t 3 23 the the DET 3b59183375t 3 24 np np PROPN 3b59183375t 3 25 system system NOUN 3b59183375t 3 26 functions function NOUN 3b59183375t 3 27 to to PART 3b59183375t 3 28 reduce reduce VERB 3b59183375t 3 29 the the DET 3b59183375t 3 30 salt salt NOUN 3b59183375t 3 31 burden burden NOUN 3b59183375t 3 32 on on ADP 3b59183375t 3 33 euryhaline euryhaline ADJ 3b59183375t 3 34 teleosts teleost NOUN 3b59183375t 3 35 following follow VERB 3b59183375t 3 36 transfer transfer NOUN 3b59183375t 3 37 from from ADP 3b59183375t 3 38 freshwater freshwater NOUN 3b59183375t 3 39 to to ADP 3b59183375t 3 40 saltwater saltwater NOUN 3b59183375t 3 41 . . PUNCT 3b59183375t 4 1 in in ADP 3b59183375t 4 2 contrast contrast NOUN 3b59183375t 4 3 , , PUNCT 3b59183375t 4 4 the the DET 3b59183375t 4 5 cardioprotective cardioprotective ADJ 3b59183375t 4 6 hypothesis hypothesis NOUN 3b59183375t 4 7 is be AUX 3b59183375t 4 8 formulated formulate VERB 3b59183375t 4 9 from from ADP 3b59183375t 4 10 empirical empirical ADJ 3b59183375t 4 11 evidence evidence NOUN 3b59183375t 4 12 from from ADP 3b59183375t 4 13 the the DET 3b59183375t 4 14 eel eel NOUN 3b59183375t 4 15 and and CCONJ 3b59183375t 4 16 trout trout NOUN 3b59183375t 4 17 , , PUNCT 3b59183375t 4 18 and and CCONJ 3b59183375t 4 19 contends contend VERB 3b59183375t 4 20 that that SCONJ 3b59183375t 4 21 the the DET 3b59183375t 4 22 np np PROPN 3b59183375t 4 23 system system NOUN 3b59183375t 4 24 in in ADP 3b59183375t 4 25 fishes fish NOUN 3b59183375t 4 26 functions function NOUN 3b59183375t 4 27 primarily primarily ADV 3b59183375t 4 28 to to PART 3b59183375t 4 29 protect protect VERB 3b59183375t 4 30 the the DET 3b59183375t 4 31 heart heart NOUN 3b59183375t 4 32 from from ADP 3b59183375t 4 33 volume volume NOUN 3b59183375t 4 34 - - PUNCT 3b59183375t 4 35 loading loading NOUN 3b59183375t 4 36 cardiodilation cardiodilation NOUN 3b59183375t 4 37 . . PUNCT 3b59183375t 5 1 results result NOUN 3b59183375t 5 2 from from ADP 3b59183375t 5 3 the the DET 3b59183375t 5 4 present present ADJ 3b59183375t 5 5 studies study NOUN 3b59183375t 5 6 support support VERB 3b59183375t 5 7 the the DET 3b59183375t 5 8 cardioprotective cardioprotective ADJ 3b59183375t 5 9 hypothesis hypothesis NOUN 3b59183375t 5 10 for for ADP 3b59183375t 5 11 the the DET 3b59183375t 5 12 np np PROPN 3b59183375t 5 13 system system NOUN 3b59183375t 5 14 in in ADP 3b59183375t 5 15 trout trout NOUN 3b59183375t 5 16 . . PUNCT 3b59183375t 6 1 following follow VERB 3b59183375t 6 2 adaptation adaptation NOUN 3b59183375t 6 3 to to ADP 3b59183375t 6 4 a a DET 3b59183375t 6 5 freshwater freshwater NOUN 3b59183375t 6 6 high high ADJ 3b59183375t 6 7 - - PUNCT 3b59183375t 6 8 salt salt NOUN 3b59183375t 6 9 diet diet NOUN 3b59183375t 6 10 ( ( PUNCT 3b59183375t 6 11 fw fw PROPN 3b59183375t 6 12 - - PUNCT 3b59183375t 6 13 hsd hsd PROPN 3b59183375t 6 14 ) ) PUNCT 3b59183375t 6 15 , , PUNCT 3b59183375t 6 16 cardiac cardiac ADJ 3b59183375t 6 17 np np PROPN 3b59183375t 6 18 transcription transcription NOUN 3b59183375t 6 19 and and CCONJ 3b59183375t 6 20 pro pro ADJ 3b59183375t 6 21 - - ADJ 3b59183375t 6 22 peptide peptide ADJ 3b59183375t 6 23 levels level NOUN 3b59183375t 6 24 were be AUX 3b59183375t 6 25 significantly significantly ADV 3b59183375t 6 26 elevated elevate VERB 3b59183375t 6 27 over over ADP 3b59183375t 6 28 levels level NOUN 3b59183375t 6 29 in in ADP 3b59183375t 6 30 freshwater freshwater NOUN 3b59183375t 6 31 ( ( PUNCT 3b59183375t 6 32 fw fw PROPN 3b59183375t 6 33 ) ) PUNCT 3b59183375t 6 34 and and CCONJ 3b59183375t 6 35 saltwater saltwater NOUN 3b59183375t 6 36 ( ( PUNCT 3b59183375t 6 37 sw sw PROPN 3b59183375t 6 38 ) ) PUNCT 3b59183375t 6 39 adapted adapt VERB 3b59183375t 6 40 fish fish NOUN 3b59183375t 6 41 . . PUNCT 3b59183375t 7 1 cardiac cardiac ADJ 3b59183375t 7 2 np np NOUN 3b59183375t 7 3 - - PUNCT 3b59183375t 7 4 receptors receptor NOUN 3b59183375t 7 5 ( ( PUNCT 3b59183375t 7 6 nprs nprs NOUN 3b59183375t 7 7 ) ) PUNCT 3b59183375t 7 8 were be AUX 3b59183375t 7 9 also also ADV 3b59183375t 7 10 significantly significantly ADV 3b59183375t 7 11 elevated elevate VERB 3b59183375t 7 12 in in ADP 3b59183375t 7 13 fw fw PROPN 3b59183375t 7 14 - - PUNCT 3b59183375t 7 15 hsd hsd PROPN 3b59183375t 7 16 trout trout NOUN 3b59183375t 7 17 as as SCONJ 3b59183375t 7 18 comared comare VERB 3b59183375t 7 19 to to ADP 3b59183375t 7 20 fw fw PROPN 3b59183375t 7 21 and and CCONJ 3b59183375t 7 22 sw sw PROPN 3b59183375t 7 23 trout trout PROPN 3b59183375t 7 24 . . PUNCT 3b59183375t 8 1 following follow VERB 3b59183375t 8 2 acute acute ADJ 3b59183375t 8 3 volume volume NOUN 3b59183375t 8 4 loading loading NOUN 3b59183375t 8 5 cardiac cardiac PROPN 3b59183375t 8 6 np np PROPN 3b59183375t 8 7 mrna mrna PROPN 3b59183375t 8 8 levels level NOUN 3b59183375t 8 9 were be AUX 3b59183375t 8 10 significantly significantly ADV 3b59183375t 8 11 elevated elevate VERB 3b59183375t 8 12 over over ADP 3b59183375t 8 13 control control NOUN 3b59183375t 8 14 , , PUNCT 3b59183375t 8 15 while while SCONJ 3b59183375t 8 16 acute acute ADJ 3b59183375t 8 17 volume volume NOUN 3b59183375t 8 18 depletion depletion NOUN 3b59183375t 8 19 typically typically ADV 3b59183375t 8 20 resulted result VERB 3b59183375t 8 21 in in ADP 3b59183375t 8 22 a a DET 3b59183375t 8 23 reduction reduction NOUN 3b59183375t 8 24 of of ADP 3b59183375t 8 25 cardiac cardiac ADJ 3b59183375t 8 26 np np PROPN 3b59183375t 8 27 mrna mrna PROPN 3b59183375t 8 28 . . PUNCT 3b59183375t 9 1 identification identification NOUN 3b59183375t 9 2 of of ADP 3b59183375t 9 3 extra extra ADJ 3b59183375t 9 4 - - ADJ 3b59183375t 9 5 cardiac cardiac ADJ 3b59183375t 9 6 np np PROPN 3b59183375t 9 7 production production NOUN 3b59183375t 9 8 sites site NOUN 3b59183375t 9 9 in in ADP 3b59183375t 9 10 the the DET 3b59183375t 9 11 brain brain NOUN 3b59183375t 9 12 and and CCONJ 3b59183375t 9 13 vasculature vasculature NOUN 3b59183375t 9 14 further far ADV 3b59183375t 9 15 supports support VERB 3b59183375t 9 16 a a DET 3b59183375t 9 17 cardioprotective cardioprotective ADJ 3b59183375t 9 18 role role NOUN 3b59183375t 9 19 for for ADP 3b59183375t 9 20 the the DET 3b59183375t 9 21 np np PROPN 3b59183375t 9 22 system system NOUN 3b59183375t 9 23 in in ADP 3b59183375t 9 24 trout trout NOUN 3b59183375t 9 25 . . PUNCT 3b59183375t 10 1 following follow VERB 3b59183375t 10 2 adaptation adaptation NOUN 3b59183375t 10 3 to to ADP 3b59183375t 10 4 fw fw PROPN 3b59183375t 10 5 - - PUNCT 3b59183375t 10 6 hsd hsd PROPN 3b59183375t 10 7 , , PUNCT 3b59183375t 10 8 brain brain NOUN 3b59183375t 10 9 pro pro NOUN 3b59183375t 10 10 - - NOUN 3b59183375t 10 11 bnp bnp ADJ 3b59183375t 10 12 , , PUNCT 3b59183375t 10 13 npr npr PROPN 3b59183375t 10 14 - - PUNCT 3b59183375t 10 15 a a PROPN 3b59183375t 10 16 and and CCONJ 3b59183375t 10 17 npr npr PROPN 3b59183375t 10 18 - - PUNCT 3b59183375t 10 19 b b NOUN 3b59183375t 10 20 mrna mrna PROPN 3b59183375t 10 21 levels level NOUN 3b59183375t 10 22 were be AUX 3b59183375t 10 23 significantly significantly ADV 3b59183375t 10 24 elevated elevate VERB 3b59183375t 10 25 over over ADP 3b59183375t 10 26 fw fw PROPN 3b59183375t 10 27 and and CCONJ 3b59183375t 10 28 sw sw PROPN 3b59183375t 10 29 adapted adapted PROPN 3b59183375t 10 30 fish fish NOUN 3b59183375t 10 31 . . PUNCT 3b59183375t 11 1 furthermore furthermore ADV 3b59183375t 11 2 , , PUNCT 3b59183375t 11 3 local local ADJ 3b59183375t 11 4 production production NOUN 3b59183375t 11 5 of of ADP 3b59183375t 11 6 bnp bnp NOUN 3b59183375t 11 7 and and CCONJ 3b59183375t 11 8 cnp cnp ADJ 3b59183375t 11 9 in in ADP 3b59183375t 11 10 the the DET 3b59183375t 11 11 trout trout NOUN 3b59183375t 11 12 vasculature vasculature NOUN 3b59183375t 11 13 supports support VERB 3b59183375t 11 14 a a DET 3b59183375t 11 15 blood blood NOUN 3b59183375t 11 16 volume volume NOUN 3b59183375t 11 17 - - PUNCT 3b59183375t 11 18 sensitive sensitive ADJ 3b59183375t 11 19 response response NOUN 3b59183375t 11 20 . . PUNCT 3b59183375t 12 1 npr npr PROPN 3b59183375t 12 2 production production NOUN 3b59183375t 12 3 in in ADP 3b59183375t 12 4 the the DET 3b59183375t 12 5 efferent efferent PROPN 3b59183375t 12 6 branchial branchial NOUN 3b59183375t 12 7 artery artery NOUN 3b59183375t 12 8 ( ( PUNCT 3b59183375t 12 9 eba eba NOUN 3b59183375t 12 10 ) ) PUNCT 3b59183375t 12 11 was be AUX 3b59183375t 12 12 not not PART 3b59183375t 12 13 significantly significantly ADV 3b59183375t 12 14 affected affect VERB 3b59183375t 12 15 by by ADP 3b59183375t 12 16 fw fw PROPN 3b59183375t 12 17 - - PUNCT 3b59183375t 12 18 hsd hsd PROPN 3b59183375t 12 19 or or CCONJ 3b59183375t 12 20 sw sw PROPN 3b59183375t 12 21 adaptation adaptation NOUN 3b59183375t 12 22 as as SCONJ 3b59183375t 12 23 compared compare VERB 3b59183375t 12 24 to to ADP 3b59183375t 12 25 fw fw PROPN 3b59183375t 12 26 , , PUNCT 3b59183375t 12 27 though though SCONJ 3b59183375t 12 28 in in ADP 3b59183375t 12 29 vitro vitro X 3b59183375t 12 30 vascular vascular ADJ 3b59183375t 12 31 sensitivity sensitivity NOUN 3b59183375t 12 32 assays assay VERB 3b59183375t 12 33 for for ADP 3b59183375t 12 34 either either CCONJ 3b59183375t 12 35 anp anp PROPN 3b59183375t 12 36 or or CCONJ 3b59183375t 12 37 cnp cnp ADJ 3b59183375t 12 38 revealed reveal VERB 3b59183375t 12 39 ebas ebas PROPN 3b59183375t 12 40 from from ADP 3b59183375t 12 41 fw fw PROPN 3b59183375t 12 42 - - PUNCT 3b59183375t 12 43 hsd hsd PROPN 3b59183375t 12 44 trout trout NOUN 3b59183375t 12 45 were be AUX 3b59183375t 12 46 significantly significantly ADV 3b59183375t 12 47 less less ADV 3b59183375t 12 48 sensitive sensitive ADJ 3b59183375t 12 49 than than ADP 3b59183375t 12 50 either either CCONJ 3b59183375t 12 51 fw fw PROPN 3b59183375t 12 52 or or CCONJ 3b59183375t 12 53 sw sw PROPN 3b59183375t 12 54 ebas ebas PROPN 3b59183375t 12 55 . . PUNCT 3b59183375t 13 1 these these DET 3b59183375t 13 2 results result NOUN 3b59183375t 13 3 show show VERB 3b59183375t 13 4 that that SCONJ 3b59183375t 13 5 the the DET 3b59183375t 13 6 production production NOUN 3b59183375t 13 7 of of ADP 3b59183375t 13 8 cardiac cardiac PROPN 3b59183375t 13 9 nps nps PROPN 3b59183375t 13 10 and and CCONJ 3b59183375t 13 11 nprs nprs NOUN 3b59183375t 13 12 is be AUX 3b59183375t 13 13 primarily primarily ADV 3b59183375t 13 14 blood blood NOUN 3b59183375t 13 15 volume volume NOUN 3b59183375t 13 16 - - PUNCT 3b59183375t 13 17 responsive responsive ADJ 3b59183375t 13 18 . . PUNCT 3b59183375t 14 1 furthermore furthermore ADV 3b59183375t 14 2 , , PUNCT 3b59183375t 14 3 np np PROPN 3b59183375t 14 4 and and CCONJ 3b59183375t 14 5 npr npr NOUN 3b59183375t 14 6 transcription transcription NOUN 3b59183375t 14 7 of of ADP 3b59183375t 14 8 extra extra ADJ 3b59183375t 14 9 - - PUNCT 3b59183375t 14 10 cardiac cardiac ADJ 3b59183375t 14 11 sites site NOUN 3b59183375t 14 12 suggest suggest VERB 3b59183375t 14 13 a a DET 3b59183375t 14 14 volume volume NOUN 3b59183375t 14 15 - - PUNCT 3b59183375t 14 16 responsive responsive ADJ 3b59183375t 14 17 role role NOUN 3b59183375t 14 18 for for ADP 3b59183375t 14 19 nps nps PROPN 3b59183375t 14 20 and and CCONJ 3b59183375t 14 21 nprs nprs NOUN 3b59183375t 14 22 in in ADP 3b59183375t 14 23 the the DET 3b59183375t 14 24 brain brain NOUN 3b59183375t 14 25 and and CCONJ 3b59183375t 14 26 vasculature vasculature NOUN 3b59183375t 14 27 . . PUNCT 3b59183375t 15 1 overall overall ADJ 3b59183375t 15 2 , , PUNCT 3b59183375t 15 3 these these DET 3b59183375t 15 4 findings finding NOUN 3b59183375t 15 5 in in ADP 3b59183375t 15 6 conjunction conjunction NOUN 3b59183375t 15 7 with with ADP 3b59183375t 15 8 numerous numerous ADJ 3b59183375t 15 9 previous previous ADJ 3b59183375t 15 10 studies study NOUN 3b59183375t 15 11 support support VERB 3b59183375t 15 12 a a DET 3b59183375t 15 13 cardioprotective cardioprotective ADJ 3b59183375t 15 14 role role NOUN 3b59183375t 15 15 for for ADP 3b59183375t 15 16 the the DET 3b59183375t 15 17 np np PROPN 3b59183375t 15 18 system system NOUN 3b59183375t 15 19 in in ADP 3b59183375t 15 20 trout trout NOUN 3b59183375t 15 21 . . PUNCT