id sid tid token lemma pos 3197xk84844 1 1 morphogenesis morphogenesis NOUN 3197xk84844 1 2 is be AUX 3197xk84844 1 3 a a DET 3197xk84844 1 4 complex complex ADJ 3197xk84844 1 5 process process NOUN 3197xk84844 1 6 that that PRON 3197xk84844 1 7 involves involve VERB 3197xk84844 1 8 the the DET 3197xk84844 1 9 integration integration NOUN 3197xk84844 1 10 of of ADP 3197xk84844 1 11 individual individual ADJ 3197xk84844 1 12 behaviors behavior NOUN 3197xk84844 1 13 of of ADP 3197xk84844 1 14 thousands thousand NOUN 3197xk84844 1 15 of of ADP 3197xk84844 1 16 cells cell NOUN 3197xk84844 1 17 throughout throughout ADP 3197xk84844 1 18 time time NOUN 3197xk84844 1 19 and and CCONJ 3197xk84844 1 20 space space NOUN 3197xk84844 1 21 . . PUNCT 3197xk84844 2 1 to to PART 3197xk84844 2 2 elucidate elucidate VERB 3197xk84844 2 3 the the DET 3197xk84844 2 4 process process NOUN 3197xk84844 2 5 is be AUX 3197xk84844 2 6 to to ADP 3197xk84844 2 7 understanding understand VERB 3197xk84844 2 8 communications communication NOUN 3197xk84844 2 9 between between ADP 3197xk84844 2 10 the the DET 3197xk84844 2 11 cells cell NOUN 3197xk84844 2 12 . . PUNCT 3197xk84844 3 1 the the DET 3197xk84844 3 2 mechanisms mechanism NOUN 3197xk84844 3 3 of of ADP 3197xk84844 3 4 communication communication NOUN 3197xk84844 3 5 include include VERB 3197xk84844 3 6 receptors receptor NOUN 3197xk84844 3 7 that that PRON 3197xk84844 3 8 transduce transduce VERB 3197xk84844 3 9 information information NOUN 3197xk84844 3 10 from from ADP 3197xk84844 3 11 extracellular extracellular ADJ 3197xk84844 3 12 to to ADP 3197xk84844 3 13 intracellular intracellular ADJ 3197xk84844 3 14 environment environment NOUN 3197xk84844 3 15 and and CCONJ 3197xk84844 3 16 second second ADJ 3197xk84844 3 17 messengers messenger NOUN 3197xk84844 3 18 that that PRON 3197xk84844 3 19 carry carry VERB 3197xk84844 3 20 the the DET 3197xk84844 3 21 information information NOUN 3197xk84844 3 22 via via ADP 3197xk84844 3 23 their their PRON 3197xk84844 3 24 dynamics dynamic NOUN 3197xk84844 3 25 to to PART 3197xk84844 3 26 inform inform VERB 3197xk84844 3 27 cell cell NOUN 3197xk84844 3 28 decision decision NOUN 3197xk84844 3 29 - - PUNCT 3197xk84844 3 30 making making NOUN 3197xk84844 3 31 . . PUNCT 3197xk84844 4 1 however however ADV 3197xk84844 4 2 , , PUNCT 3197xk84844 4 3 the the DET 3197xk84844 4 4 complexity complexity NOUN 3197xk84844 4 5 of of ADP 3197xk84844 4 6 the the DET 3197xk84844 4 7 system system NOUN 3197xk84844 4 8 poses pose VERB 3197xk84844 4 9 a a DET 3197xk84844 4 10 major major ADJ 3197xk84844 4 11 challenge challenge NOUN 3197xk84844 4 12 in in ADP 3197xk84844 4 13 efficient efficient ADJ 3197xk84844 4 14 dissecting dissect VERB 3197xk84844 4 15 the the DET 3197xk84844 4 16 mechanisms mechanism NOUN 3197xk84844 4 17 of of ADP 3197xk84844 4 18 cellular cellular ADJ 3197xk84844 4 19 and and CCONJ 3197xk84844 4 20 tissue tissue NOUN 3197xk84844 4 21 communication communication NOUN 3197xk84844 4 22 . . PUNCT 3197xk84844 5 1 therefore therefore ADV 3197xk84844 5 2 , , PUNCT 3197xk84844 5 3 an an DET 3197xk84844 5 4 integrative integrative ADJ 3197xk84844 5 5 approach approach NOUN 3197xk84844 5 6 is be AUX 3197xk84844 5 7 needed need VERB 3197xk84844 5 8 for for ADP 3197xk84844 5 9 the the DET 3197xk84844 5 10 investigating investigating NOUN 3197xk84844 5 11 and and CCONJ 3197xk84844 5 12 the the DET 3197xk84844 5 13 analysis analysis NOUN 3197xk84844 5 14 of of ADP 3197xk84844 5 15 the the DET 3197xk84844 5 16 communication communication NOUN 3197xk84844 5 17 in in ADP 3197xk84844 5 18 multicellular multicellular ADJ 3197xk84844 5 19 systems system NOUN 3197xk84844 5 20 . . PUNCT 3197xk84844 6 1 in in ADP 3197xk84844 6 2 this this DET 3197xk84844 6 3 dissertation dissertation NOUN 3197xk84844 6 4 , , PUNCT 3197xk84844 6 5 i i PRON 3197xk84844 6 6 used use VERB 3197xk84844 6 7 drosophila drosophila NOUN 3197xk84844 6 8 melanogaster melanogaster NOUN 3197xk84844 6 9 — — PUNCT 3197xk84844 6 10 a a DET 3197xk84844 6 11 classic classic ADJ 3197xk84844 6 12 model model NOUN 3197xk84844 6 13 organism organism NOUN 3197xk84844 6 14 — — PUNCT 3197xk84844 6 15 to to PART 3197xk84844 6 16 investigate investigate VERB 3197xk84844 6 17 cellular cellular ADJ 3197xk84844 6 18 and and CCONJ 3197xk84844 6 19 tissue tissue NOUN 3197xk84844 6 20 communication communication NOUN 3197xk84844 6 21 based base VERB 3197xk84844 6 22 on on ADP 3197xk84844 6 23 calcium calcium NOUN 3197xk84844 6 24 ( ( PUNCT 3197xk84844 6 25 ca2 ca2 NOUN 3197xk84844 6 26 + + NUM 3197xk84844 6 27 ) ) PUNCT 3197xk84844 6 28 and and CCONJ 3197xk84844 6 29 g g PROPN 3197xk84844 6 30 protein protein NOUN 3197xk84844 6 31 - - PUNCT 3197xk84844 6 32 coupled couple VERB 3197xk84844 6 33 receptors receptor NOUN 3197xk84844 6 34 ( ( PUNCT 3197xk84844 6 35 gpcrs gpcrs PROPN 3197xk84844 6 36 ) ) PUNCT 3197xk84844 6 37 , , PUNCT 3197xk84844 6 38 in in ADP 3197xk84844 6 39 the the DET 3197xk84844 6 40 context context NOUN 3197xk84844 6 41 of of ADP 3197xk84844 6 42 wound wound NOUN 3197xk84844 6 43 healing healing NOUN 3197xk84844 6 44 and and CCONJ 3197xk84844 6 45 tissue tissue NOUN 3197xk84844 6 46 development development NOUN 3197xk84844 6 47 . . PUNCT 3197xk84844 7 1 i i PRON 3197xk84844 7 2 reviewed review VERB 3197xk84844 7 3 the the DET 3197xk84844 7 4 most most ADJ 3197xk84844 7 5 up up ADP 3197xk84844 7 6 - - PUNCT 3197xk84844 7 7 to to ADP 3197xk84844 7 8 - - PUNCT 3197xk84844 7 9 date date NOUN 3197xk84844 7 10 advances advance NOUN 3197xk84844 7 11 of of ADP 3197xk84844 7 12 technology technology NOUN 3197xk84844 7 13 that that PRON 3197xk84844 7 14 is be AUX 3197xk84844 7 15 used use VERB 3197xk84844 7 16 to to PART 3197xk84844 7 17 reverse reverse VERB 3197xk84844 7 18 - - PUNCT 3197xk84844 7 19 engineer engineer NOUN 3197xk84844 7 20 multicellular multicellular ADJ 3197xk84844 7 21 systems system NOUN 3197xk84844 7 22 ( ( PUNCT 3197xk84844 7 23 chapter chapter NOUN 3197xk84844 7 24 1 1 NUM 3197xk84844 7 25 ) ) PUNCT 3197xk84844 7 26 . . PUNCT 3197xk84844 8 1 with with ADP 3197xk84844 8 2 these these DET 3197xk84844 8 3 tools tool NOUN 3197xk84844 8 4 , , PUNCT 3197xk84844 8 5 i i PRON 3197xk84844 8 6 conducted conduct VERB 3197xk84844 8 7 detailed detailed ADJ 3197xk84844 8 8 analysis analysis NOUN 3197xk84844 8 9 of of ADP 3197xk84844 8 10 ca2 ca2 SPACE 3197xk84844 8 11 + + CCONJ 3197xk84844 8 12 dynamics dynamic NOUN 3197xk84844 8 13 in in ADP 3197xk84844 8 14 wounded wounded ADJ 3197xk84844 8 15 and and CCONJ 3197xk84844 8 16 developing develop VERB 3197xk84844 8 17 tissues tissue NOUN 3197xk84844 8 18 ( ( PUNCT 3197xk84844 8 19 chapter chapter NOUN 3197xk84844 8 20 2 2 NUM 3197xk84844 8 21 and and CCONJ 3197xk84844 8 22 3 3 NUM 3197xk84844 8 23 ) ) PUNCT 3197xk84844 8 24 . . PUNCT 3197xk84844 9 1 the the DET 3197xk84844 9 2 analysis analysis NOUN 3197xk84844 9 3 revealed reveal VERB 3197xk84844 9 4 that that SCONJ 3197xk84844 9 5 mechanical mechanical ADJ 3197xk84844 9 6 anisotropy anisotropy NOUN 3197xk84844 9 7 within within ADP 3197xk84844 9 8 the the DET 3197xk84844 9 9 tissue tissue NOUN 3197xk84844 9 10 impact impact NOUN 3197xk84844 9 11 the the DET 3197xk84844 9 12 ca2 ca2 SPACE 3197xk84844 9 13 + + NOUN 3197xk84844 9 14 flash flash NOUN 3197xk84844 9 15 propagation propagation NOUN 3197xk84844 9 16 after after ADP 3197xk84844 9 17 wounding wound VERB 3197xk84844 9 18 ( ( PUNCT 3197xk84844 9 19 chapter chapter NOUN 3197xk84844 9 20 2 2 NUM 3197xk84844 9 21 ) ) PUNCT 3197xk84844 9 22 . . PUNCT 3197xk84844 10 1 it it PRON 3197xk84844 10 2 also also ADV 3197xk84844 10 3 demonstrated demonstrate VERB 3197xk84844 10 4 that that SCONJ 3197xk84844 10 5 ca2 ca2 SPACE 3197xk84844 10 6 + + SYM 3197xk84844 10 7 dynamics dynamic NOUN 3197xk84844 10 8 reversely reversely ADV 3197xk84844 10 9 correlate correlate VERB 3197xk84844 10 10 with with ADP 3197xk84844 10 11 progression progression NOUN 3197xk84844 10 12 of of ADP 3197xk84844 10 13 tissue tissue NOUN 3197xk84844 10 14 development development NOUN 3197xk84844 10 15 , , PUNCT 3197xk84844 10 16 potentially potentially ADV 3197xk84844 10 17 serving serve VERB 3197xk84844 10 18 as as ADP 3197xk84844 10 19 a a DET 3197xk84844 10 20 signal signal NOUN 3197xk84844 10 21 to to PART 3197xk84844 10 22 coordinate coordinate VERB 3197xk84844 10 23 collective collective ADJ 3197xk84844 10 24 behaviors behavior NOUN 3197xk84844 10 25 of of ADP 3197xk84844 10 26 cells cell NOUN 3197xk84844 10 27 within within ADP 3197xk84844 10 28 a a DET 3197xk84844 10 29 developing develop VERB 3197xk84844 10 30 tissue tissue NOUN 3197xk84844 10 31 ( ( PUNCT 3197xk84844 10 32 chapter chapter NOUN 3197xk84844 10 33 3 3 NUM 3197xk84844 10 34 ) ) PUNCT 3197xk84844 10 35 . . PUNCT 3197xk84844 11 1 the the DET 3197xk84844 11 2 implicate implicate NOUN 3197xk84844 11 3 of of ADP 3197xk84844 11 4 ca2 ca2 SPACE 3197xk84844 11 5 + + CCONJ 3197xk84844 11 6 in in ADP 3197xk84844 11 7 tissue tissue NOUN 3197xk84844 11 8 development development NOUN 3197xk84844 11 9 led lead VERB 3197xk84844 11 10 to to ADP 3197xk84844 11 11 the the DET 3197xk84844 11 12 investigation investigation NOUN 3197xk84844 11 13 of of ADP 3197xk84844 11 14 the the DET 3197xk84844 11 15 roles role NOUN 3197xk84844 11 16 of of ADP 3197xk84844 11 17 gpcrs gpcrs PROPN 3197xk84844 11 18 , , PUNCT 3197xk84844 11 19 a a DET 3197xk84844 11 20 group group NOUN 3197xk84844 11 21 of of ADP 3197xk84844 11 22 upstream upstream ADJ 3197xk84844 11 23 regulators regulator NOUN 3197xk84844 11 24 of of ADP 3197xk84844 11 25 ca2 ca2 SPACE 3197xk84844 11 26 + + CCONJ 3197xk84844 11 27 dynamics dynamic NOUN 3197xk84844 11 28 , , PUNCT 3197xk84844 11 29 during during ADP 3197xk84844 11 30 epithelial epithelial ADJ 3197xk84844 11 31 development development NOUN 3197xk84844 11 32 ( ( PUNCT 3197xk84844 11 33 chapter chapter NOUN 3197xk84844 11 34 4 4 NUM 3197xk84844 11 35 ) ) PUNCT 3197xk84844 11 36 . . PUNCT 3197xk84844 12 1 we we PRON 3197xk84844 12 2 demonstrated demonstrate VERB 3197xk84844 12 3 the the DET 3197xk84844 12 4 power power NOUN 3197xk84844 12 5 of of ADP 3197xk84844 12 6 neural neural ADJ 3197xk84844 12 7 networks network NOUN 3197xk84844 12 8 in in ADP 3197xk84844 12 9 handling handle VERB 3197xk84844 12 10 bio bio NOUN 3197xk84844 12 11 - - NOUN 3197xk84844 12 12 images image NOUN 3197xk84844 12 13 and and CCONJ 3197xk84844 12 14 the the DET 3197xk84844 12 15 efficiency efficiency NOUN 3197xk84844 12 16 of of ADP 3197xk84844 12 17 statistical statistical ADJ 3197xk84844 12 18 models model NOUN 3197xk84844 12 19 in in ADP 3197xk84844 12 20 analyzing analyze VERB 3197xk84844 12 21 complex complex ADJ 3197xk84844 12 22 structures structure NOUN 3197xk84844 12 23 of of ADP 3197xk84844 12 24 data datum NOUN 3197xk84844 12 25 . . PUNCT 3197xk84844 13 1 interestingly interestingly ADV 3197xk84844 13 2 , , PUNCT 3197xk84844 13 3 many many ADJ 3197xk84844 13 4 neuropeptide neuropeptide NOUN 3197xk84844 13 5 and and CCONJ 3197xk84844 13 6 neurotransmitter neurotransmitter NOUN 3197xk84844 13 7 receptors receptor NOUN 3197xk84844 13 8 , , PUNCT 3197xk84844 13 9 which which PRON 3197xk84844 13 10 previously previously ADV 3197xk84844 13 11 were be AUX 3197xk84844 13 12 not not PART 3197xk84844 13 13 known know VERB 3197xk84844 13 14 to to PART 3197xk84844 13 15 have have VERB 3197xk84844 13 16 functions function NOUN 3197xk84844 13 17 in in ADP 3197xk84844 13 18 morphogenesis morphogenesis PROPN 3197xk84844 13 19 , , PUNCT 3197xk84844 13 20 were be AUX 3197xk84844 13 21 shown show VERB 3197xk84844 13 22 to to PART 3197xk84844 13 23 regulate regulate VERB 3197xk84844 13 24 drosophila drosophila NOUN 3197xk84844 13 25 wing wing NOUN 3197xk84844 13 26 development development NOUN 3197xk84844 13 27 . . PUNCT 3197xk84844 14 1 the the DET 3197xk84844 14 2 finding finding NOUN 3197xk84844 14 3 demonstrated demonstrate VERB 3197xk84844 14 4 the the DET 3197xk84844 14 5 connection connection NOUN 3197xk84844 14 6 between between ADP 3197xk84844 14 7 nervous nervous ADJ 3197xk84844 14 8 - - PUNCT 3197xk84844 14 9 system system NOUN 3197xk84844 14 10 - - PUNCT 3197xk84844 14 11 related relate VERB 3197xk84844 14 12 gpcrs gpcrs PROPN 3197xk84844 14 13 and and CCONJ 3197xk84844 14 14 epithelial epithelial ADJ 3197xk84844 14 15 development development NOUN 3197xk84844 14 16 . . PUNCT 3197xk84844 15 1 in in ADP 3197xk84844 15 2 addition addition NOUN 3197xk84844 15 3 , , PUNCT 3197xk84844 15 4 drosophila drosophila NOUN 3197xk84844 15 5 brain brain NOUN 3197xk84844 15 6 was be AUX 3197xk84844 15 7 used use VERB 3197xk84844 15 8 as as ADP 3197xk84844 15 9 a a DET 3197xk84844 15 10 drug drug NOUN 3197xk84844 15 11 - - PUNCT 3197xk84844 15 12 discovery discovery NOUN 3197xk84844 15 13 platform platform NOUN 3197xk84844 15 14 for for ADP 3197xk84844 15 15 down down ADJ 3197xk84844 15 16 syndrome syndrome NOUN 3197xk84844 15 17 ( ( PUNCT 3197xk84844 15 18 chapter chapter NOUN 3197xk84844 15 19 5 5 NUM 3197xk84844 15 20 ) ) PUNCT 3197xk84844 15 21 . . PUNCT 3197xk84844 16 1 the the DET 3197xk84844 16 2 drosophila drosophila NOUN 3197xk84844 16 3 platform platform NOUN 3197xk84844 16 4 was be AUX 3197xk84844 16 5 tightly tightly ADV 3197xk84844 16 6 integrated integrate VERB 3197xk84844 16 7 with with ADP 3197xk84844 16 8 drug drug NOUN 3197xk84844 16 9 synthesis synthesis NOUN 3197xk84844 16 10 process process NOUN 3197xk84844 16 11 that that PRON 3197xk84844 16 12 accelerates accelerate VERB 3197xk84844 16 13 the the DET 3197xk84844 16 14 iteration iteration NOUN 3197xk84844 16 15 of of ADP 3197xk84844 16 16 drug drug NOUN 3197xk84844 16 17 development development NOUN 3197xk84844 16 18 and and CCONJ 3197xk84844 16 19 the the DET 3197xk84844 16 20 advancement advancement NOUN 3197xk84844 16 21 of of ADP 3197xk84844 16 22 drugs drug NOUN 3197xk84844 16 23 onto onto ADP 3197xk84844 16 24 next next ADJ 3197xk84844 16 25 - - PUNCT 3197xk84844 16 26 stage stage NOUN 3197xk84844 16 27 mouse mouse NOUN 3197xk84844 16 28 models model NOUN 3197xk84844 16 29 . . PUNCT 3197xk84844 17 1 finally finally ADV 3197xk84844 17 2 , , PUNCT 3197xk84844 17 3 future future ADJ 3197xk84844 17 4 trends trend NOUN 3197xk84844 17 5 in in ADP 3197xk84844 17 6 how how SCONJ 3197xk84844 17 7 the the DET 3197xk84844 17 8 advance advance NOUN 3197xk84844 17 9 in in ADP 3197xk84844 17 10 analytical analytical ADJ 3197xk84844 17 11 tools tool NOUN 3197xk84844 17 12 will will AUX 3197xk84844 17 13 propel propel VERB 3197xk84844 17 14 the the DET 3197xk84844 17 15 study study NOUN 3197xk84844 17 16 of of ADP 3197xk84844 17 17 cell cell NOUN 3197xk84844 17 18 communication communication NOUN 3197xk84844 17 19 and and CCONJ 3197xk84844 17 20 morphogenesis morphogenesis NOUN 3197xk84844 17 21 are be AUX 3197xk84844 17 22 discussed discuss VERB 3197xk84844 17 23 in in ADP 3197xk84844 17 24 the the DET 3197xk84844 17 25 concluding conclude VERB 3197xk84844 17 26 chapter chapter NOUN 3197xk84844 17 27 ( ( PUNCT 3197xk84844 17 28 chapter chapter NOUN 3197xk84844 17 29 6 6 NUM 3197xk84844 17 30 ) ) PUNCT 3197xk84844 17 31 . . PUNCT