id	sid	tid	token	lemma	pos
1z40ks6797n	1	1	understanding	understand	VERB
1z40ks6797n	1	2	the	the	DET
1z40ks6797n	1	3	underlying	underlying	ADJ
1z40ks6797n	1	4	mechanisms	mechanism	NOUN
1z40ks6797n	1	5	of	of	ADP
1z40ks6797n	1	6	mesenchymal	mesenchymal	NOUN
1z40ks6797n	1	7	stem	stem	NOUN
1z40ks6797n	1	8	cell	cell	NOUN
1z40ks6797n	1	9	(	(	PUNCT
1z40ks6797n	1	10	msc	msc	PROPN
1z40ks6797n	1	11	)	)	PUNCT
1z40ks6797n	1	12	mechanotransduction	mechanotransduction	NOUN
1z40ks6797n	1	13	has	have	VERB
1z40ks6797n	1	14	important	important	ADJ
1z40ks6797n	1	15	implications	implication	NOUN
1z40ks6797n	1	16	for	for	ADP
1z40ks6797n	1	17	tissue	tissue	NOUN
1z40ks6797n	1	18	engineering	engineering	NOUN
1z40ks6797n	1	19	and	and	CCONJ
1z40ks6797n	1	20	regenerative	regenerative	ADJ
1z40ks6797n	1	21	medicine	medicine	NOUN
1z40ks6797n	1	22	.	.	PUNCT
1z40ks6797n	2	1	hydrostatic	hydrostatic	ADJ
1z40ks6797n	2	2	pressure	pressure	NOUN
1z40ks6797n	2	3	(	(	PUNCT
1z40ks6797n	2	4	hp	hp	PROPN
1z40ks6797n	2	5	)	)	PUNCT
1z40ks6797n	2	6	is	be	AUX
1z40ks6797n	2	7	the	the	DET
1z40ks6797n	2	8	dominant	dominant	ADJ
1z40ks6797n	2	9	load	load	NOUN
1z40ks6797n	2	10	bearing	bear	VERB
1z40ks6797n	2	11	mechanism	mechanism	NOUN
1z40ks6797n	2	12	in	in	ADP
1z40ks6797n	2	13	joints	joint	NOUN
1z40ks6797n	2	14	;	;	PUNCT
1z40ks6797n	2	15	however	however	ADV
1z40ks6797n	2	16	,	,	PUNCT
1z40ks6797n	2	17	the	the	DET
1z40ks6797n	2	18	mechanotransductive	mechanotransductive	ADJ
1z40ks6797n	2	19	pathways	pathway	NOUN
1z40ks6797n	2	20	utilized	utilize	VERB
1z40ks6797n	2	21	in	in	ADP
1z40ks6797n	2	22	response	response	NOUN
1z40ks6797n	2	23	to	to	ADP
1z40ks6797n	2	24	hp	hp	PROPN
1z40ks6797n	2	25	are	be	AUX
1z40ks6797n	2	26	not	not	PART
1z40ks6797n	2	27	well	well	ADV
1z40ks6797n	2	28	understood	understand	VERB
1z40ks6797n	2	29	.	.	PUNCT
1z40ks6797n	3	1	cell	cell	NOUN
1z40ks6797n	3	2	-	-	PUNCT
1z40ks6797n	3	3	matrix	matrix	NOUN
1z40ks6797n	3	4	interactions	interaction	NOUN
1z40ks6797n	3	5	,	,	PUNCT
1z40ks6797n	3	6	cytoskeletal	cytoskeletal	ADJ
1z40ks6797n	3	7	organization	organization	NOUN
1z40ks6797n	3	8	,	,	PUNCT
1z40ks6797n	3	9	and	and	CCONJ
1z40ks6797n	3	10	calcium	calcium	NOUN
1z40ks6797n	3	11	ion	ion	NOUN
1z40ks6797n	3	12	(	(	PUNCT
1z40ks6797n	3	13	ca++	ca++	PROPN
1z40ks6797n	3	14	)	)	PUNCT
1z40ks6797n	3	15	signaling	signal	VERB
1z40ks6797n	3	16	have	have	AUX
1z40ks6797n	3	17	all	all	PRON
1z40ks6797n	3	18	been	be	AUX
1z40ks6797n	3	19	proposed	propose	VERB
1z40ks6797n	3	20	to	to	PART
1z40ks6797n	3	21	regulate	regulate	VERB
1z40ks6797n	3	22	msc	msc	PROPN
1z40ks6797n	3	23	mechanotransduction	mechanotransduction	NOUN
1z40ks6797n	3	24	.	.	PUNCT
1z40ks6797n	4	1	this	this	DET
1z40ks6797n	4	2	dissertation	dissertation	NOUN
1z40ks6797n	4	3	aims	aim	VERB
1z40ks6797n	4	4	to	to	PART
1z40ks6797n	4	5	provide	provide	VERB
1z40ks6797n	4	6	insight	insight	NOUN
1z40ks6797n	4	7	into	into	ADP
1z40ks6797n	4	8	the	the	DET
1z40ks6797n	4	9	roles	role	NOUN
1z40ks6797n	4	10	of	of	ADP
1z40ks6797n	4	11	these	these	DET
1z40ks6797n	4	12	pathways	pathway	NOUN
1z40ks6797n	4	13	in	in	ADP
1z40ks6797n	4	14	the	the	DET
1z40ks6797n	4	15	response	response	NOUN
1z40ks6797n	4	16	of	of	ADP
1z40ks6797n	4	17	mscs	msc	NOUN
1z40ks6797n	4	18	to	to	ADP
1z40ks6797n	4	19	hp	hp	PROPN
1z40ks6797n	4	20	.	.	PROPN
1z40ks6797n	5	1	to	to	PART
1z40ks6797n	5	2	test	test	VERB
1z40ks6797n	5	3	whether	whether	SCONJ
1z40ks6797n	5	4	the	the	DET
1z40ks6797n	5	5	response	response	NOUN
1z40ks6797n	5	6	of	of	ADP
1z40ks6797n	5	7	mscs	msc	NOUN
1z40ks6797n	5	8	to	to	ADP
1z40ks6797n	5	9	hp	hp	PROPN
1z40ks6797n	5	10	depends	depend	VERB
1z40ks6797n	5	11	on	on	ADP
1z40ks6797n	5	12	cell	cell	NOUN
1z40ks6797n	5	13	-	-	PUNCT
1z40ks6797n	5	14	matrix	matrix	NOUN
1z40ks6797n	5	15	interactions	interaction	NOUN
1z40ks6797n	5	16	,	,	PUNCT
1z40ks6797n	5	17	mscs	msc	NOUN
1z40ks6797n	5	18	were	be	AUX
1z40ks6797n	5	19	seeded	seed	VERB
1z40ks6797n	5	20	into	into	ADP
1z40ks6797n	5	21	either	either	PRON
1z40ks6797n	5	22	agarose	agarose	NOUN
1z40ks6797n	5	23	or	or	CCONJ
1z40ks6797n	5	24	fibrin	fibrin	NOUN
1z40ks6797n	5	25	hydrogels	hydrogel	NOUN
1z40ks6797n	5	26	and	and	CCONJ
1z40ks6797n	5	27	exposed	expose	VERB
1z40ks6797n	5	28	to	to	PART
1z40ks6797n	5	29	cyclic	cyclic	VERB
1z40ks6797n	5	30	hp	hp	PROPN
1z40ks6797n	5	31	.	.	PROPN
1z40ks6797n	6	1	agarose	agarose	NOUN
1z40ks6797n	6	2	hydrogels	hydrogel	NOUN
1z40ks6797n	6	3	were	be	AUX
1z40ks6797n	6	4	found	find	VERB
1z40ks6797n	6	5	to	to	PART
1z40ks6797n	6	6	support	support	VERB
1z40ks6797n	6	7	a	a	DET
1z40ks6797n	6	8	spherical	spherical	ADJ
1z40ks6797n	6	9	cellular	cellular	ADJ
1z40ks6797n	6	10	morphology	morphology	NOUN
1z40ks6797n	6	11	,	,	PUNCT
1z40ks6797n	6	12	while	while	SCONJ
1z40ks6797n	6	13	mscs	msc	NOUN
1z40ks6797n	6	14	seeded	seed	VERB
1z40ks6797n	6	15	into	into	ADP
1z40ks6797n	6	16	fibrin	fibrin	ADJ
1z40ks6797n	6	17	hydrogels	hydrogel	NOUN
1z40ks6797n	6	18	attached	attach	VERB
1z40ks6797n	6	19	and	and	CCONJ
1z40ks6797n	6	20	spread	spread	VERB
1z40ks6797n	6	21	.	.	PUNCT
1z40ks6797n	7	1	while	while	SCONJ
1z40ks6797n	7	2	agarose	agarose	NOUN
1z40ks6797n	7	3	hydrogels	hydrogel	NOUN
1z40ks6797n	7	4	better	well	ADV
1z40ks6797n	7	5	supported	support	VERB
1z40ks6797n	7	6	chondrogenesis	chondrogenesis	NOUN
1z40ks6797n	7	7	of	of	ADP
1z40ks6797n	7	8	mscs	msc	NOUN
1z40ks6797n	7	9	,	,	PUNCT
1z40ks6797n	7	10	hp	hp	PROPN
1z40ks6797n	7	11	only	only	ADV
1z40ks6797n	7	12	enhanced	enhance	VERB
1z40ks6797n	7	13	chondrogenesis	chondrogenesis	NOUN
1z40ks6797n	7	14	in	in	ADP
1z40ks6797n	7	15	fibrin	fibrin	ADJ
1z40ks6797n	7	16	hydrogels	hydrogel	NOUN
1z40ks6797n	7	17	.	.	PUNCT
1z40ks6797n	8	1	this	this	DET
1z40ks6797n	8	2	study	study	NOUN
1z40ks6797n	8	3	demonstrates	demonstrate	VERB
1z40ks6797n	8	4	that	that	SCONJ
1z40ks6797n	8	5	a	a	DET
1z40ks6797n	8	6	complex	complex	ADJ
1z40ks6797n	8	7	relationship	relationship	NOUN
1z40ks6797n	8	8	between	between	ADP
1z40ks6797n	8	9	cell	cell	NOUN
1z40ks6797n	8	10	-	-	PUNCT
1z40ks6797n	8	11	matrix	matrix	NOUN
1z40ks6797n	8	12	interactions	interaction	NOUN
1z40ks6797n	8	13	and	and	CCONJ
1z40ks6797n	8	14	hp	hp	PROPN
1z40ks6797n	8	15	mechanotransduction	mechanotransduction	NOUN
1z40ks6797n	8	16	plays	play	VERB
1z40ks6797n	8	17	a	a	DET
1z40ks6797n	8	18	key	key	ADJ
1z40ks6797n	8	19	role	role	NOUN
1z40ks6797n	8	20	in	in	ADP
1z40ks6797n	8	21	regulating	regulate	VERB
1z40ks6797n	8	22	the	the	DET
1z40ks6797n	8	23	chondrogenic	chondrogenic	ADJ
1z40ks6797n	8	24	differentiation	differentiation	NOUN
1z40ks6797n	8	25	of	of	ADP
1z40ks6797n	8	26	mscs	msc	NOUN
1z40ks6797n	8	27	.	.	PUNCT
1z40ks6797n	9	1	next	next	ADV
1z40ks6797n	9	2	,	,	PUNCT
1z40ks6797n	9	3	the	the	DET
1z40ks6797n	9	4	roles	role	NOUN
1z40ks6797n	9	5	of	of	ADP
1z40ks6797n	9	6	integrins	integrin	NOUN
1z40ks6797n	9	7	and	and	CCONJ
1z40ks6797n	9	8	the	the	DET
1z40ks6797n	9	9	cytoskeleton	cytoskeleton	NOUN
1z40ks6797n	9	10	in	in	ADP
1z40ks6797n	9	11	the	the	DET
1z40ks6797n	9	12	mechanotransduction	mechanotransduction	NOUN
1z40ks6797n	9	13	of	of	ADP
1z40ks6797n	9	14	hp	hp	PROPN
1z40ks6797n	9	15	were	be	AUX
1z40ks6797n	9	16	examined	examine	VERB
1z40ks6797n	9	17	.	.	PUNCT
1z40ks6797n	10	1	matrix	matrix	NOUN
1z40ks6797n	10	2	stiffness	stiffness	NOUN
1z40ks6797n	10	3	and/or	and/or	CCONJ
1z40ks6797n	10	4	density	density	NOUN
1z40ks6797n	10	5	modulated	modulate	VERB
1z40ks6797n	10	6	the	the	DET
1z40ks6797n	10	7	development	development	NOUN
1z40ks6797n	10	8	of	of	ADP
1z40ks6797n	10	9	the	the	DET
1z40ks6797n	10	10	pericellular	pericellular	ADJ
1z40ks6797n	10	11	matrix	matrix	NOUN
1z40ks6797n	10	12	and	and	CCONJ
1z40ks6797n	10	13	consequently	consequently	ADV
1z40ks6797n	10	14	integrin	integrin	ADV
1z40ks6797n	10	15	binding	binding	ADJ
1z40ks6797n	10	16	and	and	CCONJ
1z40ks6797n	10	17	cytoskeletal	cytoskeletal	ADJ
1z40ks6797n	10	18	structure	structure	NOUN
1z40ks6797n	10	19	.	.	PUNCT
1z40ks6797n	11	1	this	this	DET
1z40ks6797n	11	2	study	study	NOUN
1z40ks6797n	11	3	suggests	suggest	VERB
1z40ks6797n	11	4	that	that	SCONJ
1z40ks6797n	11	5	physiological	physiological	ADJ
1z40ks6797n	11	6	cues	cue	NOUN
1z40ks6797n	11	7	such	such	ADJ
1z40ks6797n	11	8	as	as	ADP
1z40ks6797n	11	9	hp	hp	PROPN
1z40ks6797n	11	10	enhance	enhance	VERB
1z40ks6797n	11	11	chondrogenesis	chondrogenesis	NOUN
1z40ks6797n	11	12	of	of	ADP
1z40ks6797n	11	13	mscs	msc	NOUN
1z40ks6797n	11	14	as	as	ADP
1z40ks6797n	11	15	the	the	DET
1z40ks6797n	11	16	pericellular	pericellular	ADJ
1z40ks6797n	11	17	environment	environment	NOUN
1z40ks6797n	11	18	matures	mature	NOUN
1z40ks6797n	11	19	and	and	CCONJ
1z40ks6797n	11	20	the	the	DET
1z40ks6797n	11	21	cytoskeleton	cytoskeleton	NOUN
1z40ks6797n	11	22	adapts	adapt	VERB
1z40ks6797n	11	23	,	,	PUNCT
1z40ks6797n	11	24	and	and	CCONJ
1z40ks6797n	11	25	points	point	VERB
1z40ks6797n	11	26	to	to	ADP
1z40ks6797n	11	27	a	a	DET
1z40ks6797n	11	28	novel	novel	ADJ
1z40ks6797n	11	29	role	role	NOUN
1z40ks6797n	11	30	for	for	ADP
1z40ks6797n	11	31	vimentin	vimentin	NOUN
1z40ks6797n	11	32	in	in	ADP
1z40ks6797n	11	33	the	the	DET
1z40ks6797n	11	34	mechanotransduction	mechanotransduction	NOUN
1z40ks6797n	11	35	of	of	ADP
1z40ks6797n	11	36	hp	hp	PROPN
1z40ks6797n	11	37	.	.	PROPN
1z40ks6797n	11	38	intracellular	intracellular	ADJ
1z40ks6797n	12	1	ca++	ca++	PROPN
1z40ks6797n	12	2	concentrations	concentration	NOUN
1z40ks6797n	12	3	have	have	AUX
1z40ks6797n	12	4	been	be	AUX
1z40ks6797n	12	5	found	find	VERB
1z40ks6797n	12	6	to	to	PART
1z40ks6797n	12	7	increase	increase	VERB
1z40ks6797n	12	8	with	with	ADP
1z40ks6797n	12	9	application	application	NOUN
1z40ks6797n	12	10	of	of	ADP
1z40ks6797n	12	11	hp	hp	PROPN
1z40ks6797n	12	12	,	,	PUNCT
1z40ks6797n	12	13	yet	yet	CCONJ
1z40ks6797n	12	14	the	the	DET
1z40ks6797n	12	15	role	role	NOUN
1z40ks6797n	12	16	of	of	ADP
1z40ks6797n	12	17	ca++	ca++	PROPN
1z40ks6797n	12	18	signaling	signal	VERB
1z40ks6797n	12	19	in	in	ADP
1z40ks6797n	12	20	the	the	DET
1z40ks6797n	12	21	mechanotransduction	mechanotransduction	NOUN
1z40ks6797n	12	22	of	of	ADP
1z40ks6797n	12	23	hp	hp	PROPN
1z40ks6797n	12	24	had	have	VERB
1z40ks6797n	12	25	yet	yet	ADV
1z40ks6797n	12	26	to	to	PART
1z40ks6797n	12	27	be	be	AUX
1z40ks6797n	12	28	investigated	investigate	VERB
1z40ks6797n	12	29	.	.	PUNCT
1z40ks6797n	13	1	ca++	ca++	PROPN
1z40ks6797n	13	2	signaling	signal	VERB
1z40ks6797n	13	3	was	be	AUX
1z40ks6797n	13	4	found	find	VERB
1z40ks6797n	13	5	to	to	PART
1z40ks6797n	13	6	regulate	regulate	VERB
1z40ks6797n	13	7	the	the	DET
1z40ks6797n	13	8	chondrogenic	chondrogenic	ADJ
1z40ks6797n	13	9	response	response	NOUN
1z40ks6797n	13	10	of	of	ADP
1z40ks6797n	13	11	mscs	msc	NOUN
1z40ks6797n	13	12	and	and	CCONJ
1z40ks6797n	13	13	modulate	modulate	VERB
1z40ks6797n	13	14	the	the	DET
1z40ks6797n	13	15	reorganization	reorganization	NOUN
1z40ks6797n	13	16	of	of	ADP
1z40ks6797n	13	17	vimentin	vimentin	NOUN
1z40ks6797n	13	18	in	in	ADP
1z40ks6797n	13	19	response	response	NOUN
1z40ks6797n	13	20	to	to	ADP
1z40ks6797n	13	21	hp	hp	PROPN
1z40ks6797n	13	22	.	.	PROPN
1z40ks6797n	14	1	further	further	PROPN
1z40ks6797n	14	2	,	,	PUNCT
1z40ks6797n	14	3	hp	hp	PROPN
1z40ks6797n	14	4	was	be	AUX
1z40ks6797n	14	5	found	find	VERB
1z40ks6797n	14	6	to	to	PART
1z40ks6797n	14	7	initiate	initiate	VERB
1z40ks6797n	14	8	ca++	ca++	PROPN
1z40ks6797n	14	9	signaling	signal	VERB
1z40ks6797n	14	10	by	by	ADP
1z40ks6797n	14	11	activating	activate	VERB
1z40ks6797n	14	12	the	the	DET
1z40ks6797n	14	13	purinergic	purinergic	NOUN
1z40ks6797n	14	14	signaling	signal	VERB
1z40ks6797n	14	15	pathway	pathway	NOUN
1z40ks6797n	14	16	.	.	PUNCT
1z40ks6797n	15	1	these	these	DET
1z40ks6797n	15	2	results	result	NOUN
1z40ks6797n	15	3	suggest	suggest	VERB
1z40ks6797n	15	4	a	a	DET
1z40ks6797n	15	5	complex	complex	ADJ
1z40ks6797n	15	6	interplay	interplay	NOUN
1z40ks6797n	15	7	between	between	ADP
1z40ks6797n	15	8	cell	cell	NOUN
1z40ks6797n	15	9	-	-	PUNCT
1z40ks6797n	15	10	matrix	matrix	NOUN
1z40ks6797n	15	11	interactions	interaction	NOUN
1z40ks6797n	15	12	and	and	CCONJ
1z40ks6797n	15	13	ca++	ca++	PROPN
1z40ks6797n	15	14	signaling	signaling	NOUN
1z40ks6797n	15	15	may	may	AUX
1z40ks6797n	15	16	transduce	transduce	VERB
1z40ks6797n	15	17	hp	hp	PROPN
1z40ks6797n	15	18	via	via	ADP
1z40ks6797n	15	19	vimentin	vimentin	NOUN
1z40ks6797n	15	20	adaptation	adaptation	NOUN
1z40ks6797n	15	21	to	to	ADP
1z40ks6797n	15	22	loading	loading	NOUN
1z40ks6797n	15	23	,	,	PUNCT
1z40ks6797n	15	24	indicating	indicate	VERB
1z40ks6797n	15	25	that	that	SCONJ
1z40ks6797n	15	26	the	the	DET
1z40ks6797n	15	27	mechanotransduction	mechanotransduction	NOUN
1z40ks6797n	15	28	of	of	ADP
1z40ks6797n	15	29	hp	hp	PROPN
1z40ks6797n	15	30	is	be	AUX
1z40ks6797n	15	31	distinct	distinct	ADJ
1z40ks6797n	15	32	from	from	ADP
1z40ks6797n	15	33	other	other	ADJ
1z40ks6797n	15	34	loading	loading	NOUN
1z40ks6797n	15	35	modalities	modality	NOUN
1z40ks6797n	15	36	.	.	PUNCT
1z40ks6797n	16	1	overall	overall	ADV
1z40ks6797n	16	2	,	,	PUNCT
1z40ks6797n	16	3	the	the	DET
1z40ks6797n	16	4	understanding	understanding	NOUN
1z40ks6797n	16	5	gained	gain	VERB
1z40ks6797n	16	6	about	about	ADP
1z40ks6797n	16	7	the	the	DET
1z40ks6797n	16	8	mechanisms	mechanism	NOUN
1z40ks6797n	16	9	regulating	regulate	VERB
1z40ks6797n	16	10	the	the	DET
1z40ks6797n	16	11	chondrogenic	chondrogenic	ADJ
1z40ks6797n	16	12	response	response	NOUN
1z40ks6797n	16	13	to	to	ADP
1z40ks6797n	16	14	hp	hp	PROPN
1z40ks6797n	16	15	could	could	AUX
1z40ks6797n	16	16	have	have	VERB
1z40ks6797n	16	17	important	important	ADJ
1z40ks6797n	16	18	implications	implication	NOUN
1z40ks6797n	16	19	for	for	ADP
1z40ks6797n	16	20	tissue	tissue	NOUN
1z40ks6797n	16	21	engineering	engineering	NOUN
1z40ks6797n	16	22	and	and	CCONJ
1z40ks6797n	16	23	regenerative	regenerative	ADJ
1z40ks6797n	16	24	medicine	medicine	NOUN
1z40ks6797n	16	25	.	.	PUNCT