id sid tid token lemma pos 1c18df68m7d 1 1 understanding understand VERB 1c18df68m7d 1 2 the the DET 1c18df68m7d 1 3 mechanism mechanism NOUN 1c18df68m7d 1 4 of of ADP 1c18df68m7d 1 5 enzymes enzyme NOUN 1c18df68m7d 1 6 has have VERB 1c18df68m7d 1 7 a a DET 1c18df68m7d 1 8 paramount paramount ADJ 1c18df68m7d 1 9 role role NOUN 1c18df68m7d 1 10 in in ADP 1c18df68m7d 1 11 drug drug NOUN 1c18df68m7d 1 12 discovery discovery NOUN 1c18df68m7d 1 13 and and CCONJ 1c18df68m7d 1 14 chemical chemical NOUN 1c18df68m7d 1 15 biology biology NOUN 1c18df68m7d 1 16 . . PUNCT 1c18df68m7d 2 1 to to PART 1c18df68m7d 2 2 reach reach VERB 1c18df68m7d 2 3 these these DET 1c18df68m7d 2 4 goals goal NOUN 1c18df68m7d 2 5 , , PUNCT 1c18df68m7d 2 6 it it PRON 1c18df68m7d 2 7 is be AUX 1c18df68m7d 2 8 necessary necessary ADJ 1c18df68m7d 2 9 to to PART 1c18df68m7d 2 10 have have VERB 1c18df68m7d 2 11 access access NOUN 1c18df68m7d 2 12 to to ADP 1c18df68m7d 2 13 chemical chemical ADJ 1c18df68m7d 2 14 tools tool NOUN 1c18df68m7d 2 15 , , PUNCT 1c18df68m7d 2 16 which which PRON 1c18df68m7d 2 17 improve improve VERB 1c18df68m7d 2 18 our our PRON 1c18df68m7d 2 19 understanding understanding NOUN 1c18df68m7d 2 20 about about ADP 1c18df68m7d 2 21 the the DET 1c18df68m7d 2 22 biochemical biochemical ADJ 1c18df68m7d 2 23 pathways pathway NOUN 1c18df68m7d 2 24 . . PUNCT 1c18df68m7d 3 1 in in ADP 1c18df68m7d 3 2 this this DET 1c18df68m7d 3 3 thesis thesis NOUN 1c18df68m7d 3 4 , , PUNCT 1c18df68m7d 3 5 the the DET 1c18df68m7d 3 6 synthesis synthesis NOUN 1c18df68m7d 3 7 of of ADP 1c18df68m7d 3 8 photocaged photocaged ADJ 1c18df68m7d 3 9 nicotinamide nicotinamide NOUN 1c18df68m7d 3 10 using use VERB 1c18df68m7d 3 11 p p NOUN 1c18df68m7d 3 12 - - PUNCT 1c18df68m7d 3 13 hydroxyphenacyl hydroxyphenacyl PROPN 1c18df68m7d 3 14 as as SCONJ 1c18df68m7d 3 15 the the DET 1c18df68m7d 3 16 caging cage VERB 1c18df68m7d 3 17 group group NOUN 1c18df68m7d 3 18 has have AUX 1c18df68m7d 3 19 been be AUX 1c18df68m7d 3 20 accomplished accomplish VERB 1c18df68m7d 3 21 and and CCONJ 1c18df68m7d 3 22 the the DET 1c18df68m7d 3 23 photophysical photophysical ADJ 1c18df68m7d 3 24 and and CCONJ 1c18df68m7d 3 25 photolytic photolytic ADJ 1c18df68m7d 3 26 properties property NOUN 1c18df68m7d 3 27 were be AUX 1c18df68m7d 3 28 established establish VERB 1c18df68m7d 3 29 . . PUNCT 1c18df68m7d 4 1 nad+ nad+ PROPN 1c18df68m7d 4 2 as as ADP 1c18df68m7d 4 3 a a DET 1c18df68m7d 4 4 redox redox ADJ 1c18df68m7d 4 5 cofactor cofactor NOUN 1c18df68m7d 4 6 plays play VERB 1c18df68m7d 4 7 a a DET 1c18df68m7d 4 8 pivotal pivotal ADJ 1c18df68m7d 4 9 role role NOUN 1c18df68m7d 4 10 in in ADP 1c18df68m7d 4 11 metabolism metabolism NOUN 1c18df68m7d 4 12 . . PUNCT 1c18df68m7d 5 1 different different ADJ 1c18df68m7d 5 2 strategies strategy NOUN 1c18df68m7d 5 3 for for ADP 1c18df68m7d 5 4 the the DET 1c18df68m7d 5 5 synthesis synthesis NOUN 1c18df68m7d 5 6 of of ADP 1c18df68m7d 5 7 nad+ nad+ PROPN 1c18df68m7d 5 8 and and CCONJ 1c18df68m7d 5 9 its its PRON 1c18df68m7d 5 10 analog analog NOUN 1c18df68m7d 5 11 were be AUX 1c18df68m7d 5 12 explored explore VERB 1c18df68m7d 5 13 by by ADP 1c18df68m7d 5 14 applying apply VERB 1c18df68m7d 5 15 the the DET 1c18df68m7d 5 16 zincke zincke PROPN 1c18df68m7d 5 17 reaction reaction NOUN 1c18df68m7d 5 18 and and CCONJ 1c18df68m7d 5 19 the the DET 1c18df68m7d 5 20 addition addition NOUN 1c18df68m7d 5 21 of of ADP 1c18df68m7d 5 22 organozinc organozinc PROPN 1c18df68m7d 5 23 reagents reagent NOUN 1c18df68m7d 5 24 . . PUNCT 1c18df68m7d 6 1 the the DET 1c18df68m7d 6 2 synthesis synthesis NOUN 1c18df68m7d 6 3 of of ADP 1c18df68m7d 6 4 the the DET 1c18df68m7d 6 5 nmn nmn ADJ 1c18df68m7d 6 6 moiety moiety NOUN 1c18df68m7d 6 7 of of ADP 1c18df68m7d 6 8 4 4 NUM 1c18df68m7d 6 9 - - PUNCT 1c18df68m7d 6 10 alkyl alkyl NOUN 1c18df68m7d 6 11 nad+ nad+ PROPN 1c18df68m7d 6 12 was be AUX 1c18df68m7d 6 13 successfully successfully ADV 1c18df68m7d 6 14 developed develop VERB 1c18df68m7d 6 15 by by ADP 1c18df68m7d 6 16 chemoselective chemoselective ADJ 1c18df68m7d 6 17 addition addition NOUN 1c18df68m7d 6 18 of of ADP 1c18df68m7d 6 19 organozinc organozinc PROPN 1c18df68m7d 6 20 reagents reagent NOUN 1c18df68m7d 6 21 . . PUNCT 1c18df68m7d 7 1 finally finally ADV 1c18df68m7d 7 2 , , PUNCT 1c18df68m7d 7 3 palladium palladium NOUN 1c18df68m7d 7 4 catalyzes catalyze VERB 1c18df68m7d 7 5 the the DET 1c18df68m7d 7 6 asymmetric asymmetric ADJ 1c18df68m7d 7 7 conjugation conjugation PROPN 1c18df68m7d 7 8 addition addition NOUN 1c18df68m7d 7 9 to to ADP 1c18df68m7d 7 10 cyclic cyclic ADJ 1c18df68m7d 7 11 enones enones PROPN 1c18df68m7d 7 12 for for ADP 1c18df68m7d 7 13 generating generate VERB 1c18df68m7d 7 14 quaternary quaternary ADJ 1c18df68m7d 7 15 carbon carbon NOUN 1c18df68m7d 7 16 centers center NOUN 1c18df68m7d 7 17 using use VERB 1c18df68m7d 7 18 novel novel ADJ 1c18df68m7d 7 19 chiral chiral ADJ 1c18df68m7d 7 20 pyridine pyridine NOUN 1c18df68m7d 7 21 - - PUNCT 1c18df68m7d 7 22 oxazolines oxazoline NOUN 1c18df68m7d 7 23 ligands ligand NOUN 1c18df68m7d 7 24 , , PUNCT 1c18df68m7d 7 25 which which PRON 1c18df68m7d 7 26 were be AUX 1c18df68m7d 7 27 explored explore VERB 1c18df68m7d 7 28 to to PART 1c18df68m7d 7 29 experimentally experimentally ADV 1c18df68m7d 7 30 test test VERB 1c18df68m7d 7 31 computational computational ADJ 1c18df68m7d 7 32 predictions prediction NOUN 1c18df68m7d 7 33 of of ADP 1c18df68m7d 7 34 stereoselectivity stereoselectivity NOUN 1c18df68m7d 7 35 . . PUNCT