id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
w0892805b86	Casey Duchesne Stefanski	Adenomatous Polyposis Coli Regulates ABC Transporters and DNA Repair Mechanisms to Cause Doxorubicin Resistance	2022		.txt	text/plain	370	18	37	We hypothesized that APC loss prevents DOX-mediated apoptosis through: 1) reduced intracellular DOX and 2) alterations in DNA damage and repair with the goal to discover new combination therapies for APC-deficient cancer. Taken together, APC loss decreased intracellular DOX accumulation through increased efflux and decreased DOX-induced DNA damage.	cache/w0892805b86.txt	txt/w0892805b86.txt