id author title date pages extension mime words sentence flesch summary cache txt tb09j388g0m Matthew Ryan Wilson Synthesis, Conformational Analysis, and Biological Evaluation of the Potent Microtubule-Stabilizing Agents, (–)-Zampanolide and (–)-Dactylolide 2015 .txt text/plain 352 14 25 A detailed knowledge of zampanolide and dactylolide's solution conformational preferences not only helped identify its bioactive conformation but also significantly aided in the development of simplified analogues. Interestingly, Riccio and co-workers isolated a structurally related natural product, (+)-dactylolide, off the coast of the Vanuatu islands and reported dactylolide displays moderate cytotoxicity in the low μM range. cache/tb09j388g0m.txt txt/tb09j388g0m.txt