id author title date pages extension mime words sentence flesch summary cache txt t148ff39q2r Karlie E. Cox Using Small Molecule Adjuvants to Combat Bacterial Resistance Mechanisms 2021 .txt text/plain 400 19 30 To explore this concept, the National Cancer Institute (NCI) Natural Product Library Set IV was screened for adjuvant activity using four classes of antibiotics (β-lactams, aminoglycosides, macrolides, and polymyxins) against three bacterial pathogens (methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumannii, and Klebsiella pneumoniae). One such approach, is the identification of antibiotic adjuvants that re-sensitize resistant bacteria to an antibiotic, broaden the spectrum of an antibiotic, or decrease the needed antibiotic dose, while possessing limited or no antimicrobial activity itself. cache/t148ff39q2r.txt txt/t148ff39q2r.txt