id author title date pages extension mime words sentence flesch summary cache txt qv33rv0753n Julia Beck Plasminogen Activation, Conformation, and Binding in the Context of Group A Streptococcus Virulence Factors, Streptokinase and PAM 1904 .txt text/plain 285 13 55 Plasminogen (hPg) conversion to the serine protease plasmin via host and exogenous factors results in activation of the human fibrinolytic system and ultimately degradation of fibrin and extracellular matrices. Group A Streptococcus (GAS), a bacterial pathogen responsible for diseases including rheumatic heart disease, impetigo, and necrotizing fasciitis; activates Pg through the extracellular protein streptokinase (SK). cache/qv33rv0753n.txt txt/qv33rv0753n.txt