id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
pr76f190d5t	Kurt Henry Piepenbrink	Understanding the Energetic Basis for T-cell Receptor Recognition	2011		.txt	text/plain	339	12	53	The interaction energy between those two residues is defined as native free energy change minus the free energy changes of the two single mutants, plus the free energy change of the double-mutant; ddGint = dG(Xwt-Ywt) - dG(Xz->A,Ywt) - dG(Xwt,Yz->A) + dG(Xz->A,Yz->A). In a double mutant cycle between two residues, binding experiments are performed between i) the native partners, ii) the two partners with one residue mutated to alanine, iii) the two partners with the other residue mutated to alanine and iv) the two partners with both residues mutated to alanine.	cache/pr76f190d5t.txt	txt/pr76f190d5t.txt