id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
pg15bc41d9h	Yingjia Ni	Functional Screen Identifies Triple-Negative Breast Cancer Vulnerability Driven by Death Effector Domain-Containing Protein	2019		.txt	text/plain	248	9	20	Taken together, my study revealed a TNBC-specific vulnerability conferred by DEDD-driven dysregulated cell cycle progression and provided a rationale for the clinical application of CDK4/6 inhibitor containing combinatorial regimens for TNBC patients. Clinically, despite the successes of cyclin D kinase CDK 4/6 inhibitors in breast cancer, TNBC patients have been excluded from CDK 4/6 inhibitors clinical trials due to the perceived high frequency of Rb loss.	cache/pg15bc41d9h.txt	txt/pg15bc41d9h.txt