id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
p8418k74q1b	Brianna R. Mullins (Norris)	Elucidating Mechanisms of Leishmania Signaling Pathways and Parasite Stress Response	1904		.txt	text/plain	396	16	21	In this dissertation, I address the significance of signal transduction cascades during Leishmania parasite differentiation for the purpose of identifying potential drug targets to be used for the treatment of leishmaniasis, a disease characterized by a spectrum of clinical manifestations ranging from ulcerative skin lesions to fatal visceral infections. Though protein kinases, and their downstream targets, have been more actively studied for the potential development of anti-parasitic therapeutics, our understanding of the biology of protein phosphatases in Leishmania is poor despite their implication in critical post-translational modifications and differentiation.	cache/p8418k74q1b.txt	txt/p8418k74q1b.txt