id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
ng451g08f94	Hope B. Pearson	BMP-2 Indirectly Induces Angiogenesis During Large Bone Defect Regeneration	1904		.txt	text/plain	350	16	30	To determine whether the angiogenic response to growth factor stimulation was a direct effect of endothelial cell activation or a paracrine effect induced by bone formation, we treated endothelial colony forming cells (ECFCs) with BMP-2, TPO, or hMSC conditioned media and evaluated migration, tubulogenesis, and SMAD 1/5/9 nuclear localization in vitro. These data suggest that the effect of BMP-2 on angiogenesis is secondary to bone formation-induced vascular recruitment rather than direct endothelial cell activation.	cache/ng451g08f94.txt	txt/ng451g08f94.txt