id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
nc580k25k42	Angela R. Smith	Peptide Anchor Modifications Modulate T Cell Receptor Recognition of a Melanoma-Associated Antigen	2021		.txt	text/plain	258	9	31	Finding that gp100209-specific TCRs are sensitive to peptide anchor modifications, I show that, in contrast to previously published work, the enhanced tumor control properties of the SILv44 TCR are a result of strong TCR binding affinity to the WT peptide antigen. The association between peptide binding affinity and immunogenicity has led to the engineering of modified peptides with improved MHC binding, with the hope that these peptides would be useful for eliciting cross-reactive immune responses directed toward their weak binding, unmodified counterparts.	cache/nc580k25k42.txt	txt/nc580k25k42.txt