id author title date pages extension mime words sentence flesch summary cache txt n296ww74p23 Andrew Ward Improved Synthesis of the Novel Anti-Tuberculosis Drug SQ109 and Synthesis of Nitroso-ene Analogs 2011 .txt text/plain 174 7 46 SQ109 (1) has shown very promising activity against Mycobacterium tuberculosis (Mtb), but exhibits low oral bioavailability. Despite the advances made in the middle of the 20th century to combat tuberculosis, the current short-course therapy has been met with challenges from multi-drug resistant strains of bacteria as well as the inability of providing these drugs to immunocompromised patients with HIV. cache/n296ww74p23.txt txt/n296ww74p23.txt