id author title date pages extension mime words sentence flesch summary cache txt mc87pn92m5k Sara M. Brackett Using Small Molecules to Disarm Antibiotic Resistance 2019 .txt text/plain 362 16 24 This work describes a structure activity relationship (SAR) study based on a lead compound that has previously displayed biofilm inhibition and dispersion activity and β-lactam potentiation against Mycobacterium tuberculosis. This SAR study revealed that the meridianin D analogues lack β-lactam potentiation capabilities, but replacing the 2-aminopyrimidine moiety attached to the indole with a 2-aminoimidazole group led to enhanced biofilm inhibition and dispersion activity. cache/mc87pn92m5k.txt txt/mc87pn92m5k.txt