id author title date pages extension mime words sentence flesch summary cache txt gm80ht27s0n Jenifer B. Gifford GRP78 Associated Chemoresistance Affects Drug Response in Pancreatic Ductal Adenocarcinoma 1904 .txt text/plain 274 11 50 Because GRP78 has been connected to poor prognosis across cancer types and treatments, it is possible that GRP78 targeting, via IT-139, can be used to improve the efficacy of chemotherapeutics in cancers beyond GEM therapy in PDAC. It was established that induction of GRP78, an endoplasmic reticulum chaperone protein, has a direct relationship with the GEM-resistant status of pancreatic cancer cell lines and tumors. cache/gm80ht27s0n.txt txt/gm80ht27s0n.txt