id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
gm80ht2727j	Francis Kobina Insaidoo	Dynamics of Peptides Bound to Class I Major Histocompatibility Complex Proteins: Implications for T-Cell Receptor Recognition in the Immune Response	2010		.txt	text/plain	427	14	19	Using the Tax11-19 peptide bound to the 45 kD human class I MHC HLA-A2 as a model system, it is evident that peptides generated in this manner can be well characterized in MHC binding grooves by NMR, providing the opportunity to more precisely study the role of peptide dynamics in TCR recognition, specificity, and cross-reactivity. This study describe methodologies for characterizing peptide dynamics within MHC binding grooves via NMR, using a biosynthetic approach for producing labeled peptide in which the peptide is fused to ubiquitin and a ubiquitin dehydrolase used to liberate the peptide.	cache/gm80ht2727j.txt	txt/gm80ht2727j.txt