id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
f7623b61c1w	Shahram Jevin Poureetezadi	Prostaglandins as Regulators of Nephrogenesis	1904		.txt	text/plain	271	10	25	Taken together, these findings show for the first time that prostaglandin signaling is an essential component of nephron cell fate choice, and indicate that the prostaglandin family may have considerable implications in understanding how to treat kidney failure that arise from congenital kidney diseases and end-stage renal disease. Genetic abrogation or inhibition of the prostaglandin producing enzymes, Prostaglandin-endoperoxide synthase 1 or 2a (also known as Cox-1/Ptgs1 and Cox-2/Ptgs2a respectively), or the Prostaglandin E receptor 2a or 4a (Ptger2a, Ptger4a), which we found to be expressed in renal progenitors, triggered an alteration in the balance of distal segment fates.	cache/f7623b61c1w.txt	txt/f7623b61c1w.txt