id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
df65v696391	Cristhian Umaña Gamboa	Designing Structural and Conformational Analogs from Polyketide Natural Products	2023		.txt	text/plain	264	11	31	Our laboratory has utilized total synthesis, semi-synthesis, and fermentation of bacterial species to produce natural product analogs to study the relationship between conformational preferences and biological activity. In the case of zampanolide, it was demonstrated that the linear analog exhibited potent biological activity due to the conservation of an allylic strain, which restricted the conformational flexibility of the molecule.	cache/df65v696391.txt	txt/df65v696391.txt