id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
d504rj45509	Matthew J. Meagher	Engineering Synthetic Bone Graft Substitutes with Improved Mechanical Properties, Enhanced Bioactivity, and On-Demand Growth Factor Delivery	1904		.txt	text/plain	273	10	11	In a subsequent study using an orthotopic critical-size femoral defect model in rats, collagen scaffolds did not exhibit bone formation, while HA-collagen scaffolds exhibited bone formation but did not result in mechanically competent union, confirming the need to augment scaffolds with exogenous growth factors for functional bone regeneration. HA promoted angiogenesis and osteogenesis in collagen scaffolds that did not otherwise exhibit angiogenesis and osteogenesis, and the effect was dose dependent.	cache/d504rj45509.txt	txt/d504rj45509.txt