id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
73666398x1n	Taylor R. Quinn	Microsecond Simulations of the PmHMGR Second Hydride Transfer Transition State and Investigations into Molecule and Enzyme Dynamics	2020		.txt	text/plain	282	11	41	In this thesis, I will primarily discuss how molecular dynamics simulations of the transition state of PmHMGR compared to ground state simulations facilitated the prediction of allosteric residues that help stabilize the transition state of the enzyme. Molecular dynamics was used to help drug discovery efforts for the epigenetic HDAC and P300/CBP systems, which, in the case of the latter, shed light on the role of protein dynamics on the ligand-protein and protein-protein interface.	cache/73666398x1n.txt	txt/73666398x1n.txt