id author title date pages extension mime words sentence flesch summary cache txt 4j03cz33p96 Matthew Rhodes Investigating the Polyketide Metabolite GEX1A: A Splicing Inhibitor with Implications for Niemann-Pick Type C Disease 2021 .txt text/plain 294 13 32 Accessory domains and post polyketide synthesis tailoring install many oxidative and stereochemically relevant elements necessary for biological activity. Our laboratory has utilized total synthesis, semi-synthesis, and fermentation of bacterial species to produce the natural products and analogs of the natural product to study the structures and conformational preferences and the respective relationships to biological activity. cache/4j03cz33p96.txt txt/4j03cz33p96.txt