id author title date pages extension mime words sentence flesch summary cache txt 44558d00594 Timothy P. Riley Structure Guided Design and Computational Screening in Cellular Immunity 1904 .txt text/plain 193 8 25 Here, we address these hallmarks of TCR recognition, emphasizing the use of computational models and structure guided design to examine the fine details of TCR interfaces. With broad implications to T cell based immunotherapies, we highlight how the 'imperfect' interfaces of TCRs bound to their ligands influences aspects of TCR design, T cell specificity, and epitope recognition of the immune system. cache/44558d00594.txt txt/44558d00594.txt