id author title date pages extension mime words sentence flesch summary cache txt 41687h16573 Stephanie M. Schmidt Shearing Oscillatory Interstitial Fluid Flows affect Solute Transport and Osteogenesis in Cortical Bone 2006 .txt text/plain 363 12 30 The objective of this research was to: 1) propose a theoretical model for enhanced mass transport in cortical bone due to shearing oscillatory fluid flow dependent on molecular size, strain magnitude, and frequency; 2) demonstrate experimentally that oscillating fluid flows affect the mass transport of particles in sheep cortical bone; 3) prove that increased nutrient levels influence bone cell osteogenesis and metabolism in-vitro; 4) develop calcium phosphate nano-carriers for nutrients and drugs deliverable through the new mechanism. In addition, in-vitro experiments showed that bone cell osteogenesis was affected by core-shell and mesoporous calcium phosphate nano-carriers. cache/41687h16573.txt txt/41687h16573.txt