id	sid	tid	token	lemma	pos
work_clhxj3r6pndirghkema3cc6pny	1	1	From	from	IN
work_clhxj3r6pndirghkema3cc6pny	1	2	Individualized	individualized	JJ
work_clhxj3r6pndirghkema3cc6pny	1	3	Treatment	Treatment	NNP
work_clhxj3r6pndirghkema3cc6pny	1	4	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	1	5	Sickle	Sickle	NNP
work_clhxj3r6pndirghkema3cc6pny	1	6	Cell	Cell	NNP
work_clhxj3r6pndirghkema3cc6pny	1	7	Pain	Pain	NNP
work_clhxj3r6pndirghkema3cc6pny	1	8	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	1	9	Precision	Precision	NNP
work_clhxj3r6pndirghkema3cc6pny	1	10	Medicine	Medicine	NNP
work_clhxj3r6pndirghkema3cc6pny	1	11	:	:	:
work_clhxj3r6pndirghkema3cc6pny	1	12	A	a	DT
work_clhxj3r6pndirghkema3cc6pny	1	13	40-Year	40-year	CD
work_clhxj3r6pndirghkema3cc6pny	1	14	Journey	Journey	NNP
work_clhxj3r6pndirghkema3cc6pny	1	15	Articles	Articles	NNPS
work_clhxj3r6pndirghkema3cc6pny	1	16	©	©	NNP
work_clhxj3r6pndirghkema3cc6pny	1	17	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	1	18	authors	author	NNS
work_clhxj3r6pndirghkema3cc6pny	1	19	|	|	NNP
work_clhxj3r6pndirghkema3cc6pny	1	20	Journal	Journal	NNP
work_clhxj3r6pndirghkema3cc6pny	1	21	compilation	compilation	NN
work_clhxj3r6pndirghkema3cc6pny	1	22	©	©	NNP
work_clhxj3r6pndirghkema3cc6pny	1	23	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	1	24	Clin	Clin	NNP
work_clhxj3r6pndirghkema3cc6pny	1	25	Med	Med	NNP
work_clhxj3r6pndirghkema3cc6pny	1	26	Res	Res	NNP
work_clhxj3r6pndirghkema3cc6pny	1	27	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	1	28	Elmer	Elmer	NNP
work_clhxj3r6pndirghkema3cc6pny	1	29	Press	Press	NNP
work_clhxj3r6pndirghkema3cc6pny	1	30	Inc	Inc	NNP
work_clhxj3r6pndirghkema3cc6pny	1	31	™	™	CD
work_clhxj3r6pndirghkema3cc6pny	1	32	|	|	NNP
work_clhxj3r6pndirghkema3cc6pny	1	33	www.jocmr.org	www.jocmr.org	IN
work_clhxj3r6pndirghkema3cc6pny	1	34	This	this	DT
work_clhxj3r6pndirghkema3cc6pny	1	35	is	be	VBZ
work_clhxj3r6pndirghkema3cc6pny	1	36	an	an	DT
work_clhxj3r6pndirghkema3cc6pny	1	37	open	open	JJ
work_clhxj3r6pndirghkema3cc6pny	1	38	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	1	39	access	access	NN
work_clhxj3r6pndirghkema3cc6pny	1	40	article	article	NN
work_clhxj3r6pndirghkema3cc6pny	1	41	distributed	distribute	VBN
work_clhxj3r6pndirghkema3cc6pny	1	42	under	under	IN
work_clhxj3r6pndirghkema3cc6pny	1	43	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	1	44	terms	term	NNS
work_clhxj3r6pndirghkema3cc6pny	1	45	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	1	46	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	1	47	Creative	Creative	NNP
work_clhxj3r6pndirghkema3cc6pny	1	48	Commons	Commons	NNP
work_clhxj3r6pndirghkema3cc6pny	1	49	Attribution	Attribution	NNP
work_clhxj3r6pndirghkema3cc6pny	1	50	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	1	51	NonCommercial	NonCommercial	NNP
work_clhxj3r6pndirghkema3cc6pny	1	52	4.0	4.0	CD
work_clhxj3r6pndirghkema3cc6pny	1	53	International	International	NNP
work_clhxj3r6pndirghkema3cc6pny	1	54	License	License	NNP
work_clhxj3r6pndirghkema3cc6pny	1	55	,	,	,
work_clhxj3r6pndirghkema3cc6pny	1	56	which	which	WDT
work_clhxj3r6pndirghkema3cc6pny	1	57	permits	permit	VBZ
work_clhxj3r6pndirghkema3cc6pny	1	58	unrestricted	unrestricte	VBD
work_clhxj3r6pndirghkema3cc6pny	1	59	non	non	JJ
work_clhxj3r6pndirghkema3cc6pny	1	60	-	-	JJ
work_clhxj3r6pndirghkema3cc6pny	1	61	commercial	commercial	JJ
work_clhxj3r6pndirghkema3cc6pny	1	62	use	use	NN
work_clhxj3r6pndirghkema3cc6pny	1	63	,	,	,
work_clhxj3r6pndirghkema3cc6pny	1	64	distribution	distribution	NN
work_clhxj3r6pndirghkema3cc6pny	1	65	,	,	,
work_clhxj3r6pndirghkema3cc6pny	1	66	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	1	67	reproduction	reproduction	NN
work_clhxj3r6pndirghkema3cc6pny	1	68	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	1	69	any	any	DT
work_clhxj3r6pndirghkema3cc6pny	1	70	medium	medium	NN
work_clhxj3r6pndirghkema3cc6pny	1	71	,	,	,
work_clhxj3r6pndirghkema3cc6pny	1	72	provided	provide	VBD
work_clhxj3r6pndirghkema3cc6pny	1	73	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	1	74	original	original	JJ
work_clhxj3r6pndirghkema3cc6pny	1	75	work	work	NN
work_clhxj3r6pndirghkema3cc6pny	1	76	is	be	VBZ
work_clhxj3r6pndirghkema3cc6pny	1	77	properly	properly	RB
work_clhxj3r6pndirghkema3cc6pny	1	78	cited	cite	VBN
work_clhxj3r6pndirghkema3cc6pny	1	79	357	357	CD
work_clhxj3r6pndirghkema3cc6pny	1	80	Review	Review	NNP
work_clhxj3r6pndirghkema3cc6pny	1	81	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	1	82	Clin	Clin	NNP
work_clhxj3r6pndirghkema3cc6pny	1	83	Med	Med	NNP
work_clhxj3r6pndirghkema3cc6pny	1	84	Res	Res	NNP
work_clhxj3r6pndirghkema3cc6pny	1	85	.	.	.
work_clhxj3r6pndirghkema3cc6pny	2	1	2016;8(5):357	2016;8(5):357	CD
work_clhxj3r6pndirghkema3cc6pny	2	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	2	3	360	360	CD
work_clhxj3r6pndirghkema3cc6pny	2	4	ressElmer	resselmer	NN
work_clhxj3r6pndirghkema3cc6pny	2	5	From	from	IN
work_clhxj3r6pndirghkema3cc6pny	2	6	Individualized	individualized	JJ
work_clhxj3r6pndirghkema3cc6pny	2	7	Treatment	Treatment	NNP
work_clhxj3r6pndirghkema3cc6pny	2	8	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	2	9	Sickle	Sickle	NNP
work_clhxj3r6pndirghkema3cc6pny	2	10	Cell	Cell	NNP
work_clhxj3r6pndirghkema3cc6pny	2	11	Pain	Pain	NNP
work_clhxj3r6pndirghkema3cc6pny	2	12	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	2	13	Precision	Precision	NNP
work_clhxj3r6pndirghkema3cc6pny	2	14	Medicine	Medicine	NNP
work_clhxj3r6pndirghkema3cc6pny	2	15	:	:	:
work_clhxj3r6pndirghkema3cc6pny	2	16	A	a	DT
work_clhxj3r6pndirghkema3cc6pny	2	17	40-Year	40-year	CD
work_clhxj3r6pndirghkema3cc6pny	2	18	Journey	Journey	NNP
work_clhxj3r6pndirghkema3cc6pny	2	19	Samir	Samir	NNP
work_clhxj3r6pndirghkema3cc6pny	2	20	K.	K.	NNP
work_clhxj3r6pndirghkema3cc6pny	2	21	Ballas	Ballas	NNP
work_clhxj3r6pndirghkema3cc6pny	2	22	Abstract	Abstract	NNP
work_clhxj3r6pndirghkema3cc6pny	2	23	In	in	IN
work_clhxj3r6pndirghkema3cc6pny	2	24	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	2	25	1970s	1970	NNS
work_clhxj3r6pndirghkema3cc6pny	2	26	,	,	,
work_clhxj3r6pndirghkema3cc6pny	2	27	sickle	sickle	NN
work_clhxj3r6pndirghkema3cc6pny	2	28	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	2	29	pain	pain	NN
work_clhxj3r6pndirghkema3cc6pny	2	30	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	2	31	treated	treat	VBN
work_clhxj3r6pndirghkema3cc6pny	2	32	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	2	33	trial	trial	NN
work_clhxj3r6pndirghkema3cc6pny	2	34	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	2	35	error	error	NN
work_clhxj3r6pndirghkema3cc6pny	2	36	approach	approach	NN
work_clhxj3r6pndirghkema3cc6pny	2	37	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	2	38	increasing	increase	VBG
work_clhxj3r6pndirghkema3cc6pny	2	39	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	2	40	decreasing	decrease	VBG
work_clhxj3r6pndirghkema3cc6pny	2	41	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	2	42	dose	dose	NN
work_clhxj3r6pndirghkema3cc6pny	2	43	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	2	44	an	an	DT
work_clhxj3r6pndirghkema3cc6pny	2	45	opioid	opioid	NN
work_clhxj3r6pndirghkema3cc6pny	2	46	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	2	47	switching	switch	VBG
work_clhxj3r6pndirghkema3cc6pny	2	48	from	from	IN
work_clhxj3r6pndirghkema3cc6pny	2	49	one	one	CD
work_clhxj3r6pndirghkema3cc6pny	2	50	analgesic	analgesic	NN
work_clhxj3r6pndirghkema3cc6pny	2	51	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	2	52	another	another	DT
work_clhxj3r6pndirghkema3cc6pny	2	53	.	.	.
work_clhxj3r6pndirghkema3cc6pny	3	1	This	this	DT
work_clhxj3r6pndirghkema3cc6pny	3	2	approach	approach	NN
work_clhxj3r6pndirghkema3cc6pny	3	3	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	3	4	controversial	controversial	JJ
work_clhxj3r6pndirghkema3cc6pny	3	5	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	3	6	criti-	criti-	NNP
work_clhxj3r6pndirghkema3cc6pny	3	7	cism	cism	NNP
work_clhxj3r6pndirghkema3cc6pny	3	8	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	3	9	doubt	doubt	NN
work_clhxj3r6pndirghkema3cc6pny	3	10	about	about	IN
work_clhxj3r6pndirghkema3cc6pny	3	11	its	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	3	12	usefulness	usefulness	NN
work_clhxj3r6pndirghkema3cc6pny	3	13	.	.	.
work_clhxj3r6pndirghkema3cc6pny	4	1	Since	since	IN
work_clhxj3r6pndirghkema3cc6pny	4	2	then	then	RB
work_clhxj3r6pndirghkema3cc6pny	4	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	4	4	advances	advance	NNS
work_clhxj3r6pndirghkema3cc6pny	4	5	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	4	6	deter-	deter-	NN
work_clhxj3r6pndirghkema3cc6pny	4	7	mining	mine	VBG
work_clhxj3r6pndirghkema3cc6pny	4	8	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	4	9	structure	structure	NN
work_clhxj3r6pndirghkema3cc6pny	4	10	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	4	11	opioid	opioid	JJ
work_clhxj3r6pndirghkema3cc6pny	4	12	receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	4	13	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	4	14	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	4	15	role	role	NN
work_clhxj3r6pndirghkema3cc6pny	4	16	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	4	17	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	4	18	CYP450	CYP450	NNP
work_clhxj3r6pndirghkema3cc6pny	4	19	enzymes	enzyme	NNS
work_clhxj3r6pndirghkema3cc6pny	4	20	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	4	21	metabolizing	metabolize	VBG
work_clhxj3r6pndirghkema3cc6pny	4	22	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	4	23	revealed	reveal	VBD
work_clhxj3r6pndirghkema3cc6pny	4	24	that	that	IN
work_clhxj3r6pndirghkema3cc6pny	4	25	these	these	DT
work_clhxj3r6pndirghkema3cc6pny	4	26	anatomic	anatomic	JJ
work_clhxj3r6pndirghkema3cc6pny	4	27	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	4	28	metabolic	metabolic	JJ
work_clhxj3r6pndirghkema3cc6pny	4	29	findings	finding	NNS
work_clhxj3r6pndirghkema3cc6pny	4	30	are	be	VBP
work_clhxj3r6pndirghkema3cc6pny	4	31	not	not	RB
work_clhxj3r6pndirghkema3cc6pny	4	32	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	4	33	same	same	JJ
work_clhxj3r6pndirghkema3cc6pny	4	34	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	4	35	all	all	DT
work_clhxj3r6pndirghkema3cc6pny	4	36	persons	person	NNS
work_clhxj3r6pndirghkema3cc6pny	4	37	,	,	,
work_clhxj3r6pndirghkema3cc6pny	4	38	thus	thus	RB
work_clhxj3r6pndirghkema3cc6pny	4	39	explaining	explain	VBG
work_clhxj3r6pndirghkema3cc6pny	4	40	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	4	41	variability	variability	NN
work_clhxj3r6pndirghkema3cc6pny	4	42	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	4	43	response	response	NN
work_clhxj3r6pndirghkema3cc6pny	4	44	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	4	45	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	4	46	among	among	IN
work_clhxj3r6pndirghkema3cc6pny	4	47	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	4	48	.	.	.
work_clhxj3r6pndirghkema3cc6pny	5	1	Thus	thus	RB
work_clhxj3r6pndirghkema3cc6pny	5	2	,	,	,
work_clhxj3r6pndirghkema3cc6pny	5	3	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	5	4	“	"	``
work_clhxj3r6pndirghkema3cc6pny	5	5	trial	trial	NN
work_clhxj3r6pndirghkema3cc6pny	5	6	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	5	7	error	error	NN
work_clhxj3r6pndirghkema3cc6pny	5	8	approach	approach	NN
work_clhxj3r6pndirghkema3cc6pny	5	9	”	"	''
work_clhxj3r6pndirghkema3cc6pny	5	10	has	have	VBZ
work_clhxj3r6pndirghkema3cc6pny	5	11	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	5	12	scientific	scientific	JJ
work_clhxj3r6pndirghkema3cc6pny	5	13	basis	basis	NN
work_clhxj3r6pndirghkema3cc6pny	5	14	after	after	RB
work_clhxj3r6pndirghkema3cc6pny	5	15	all	all	RB
work_clhxj3r6pndirghkema3cc6pny	5	16	.	.	.
work_clhxj3r6pndirghkema3cc6pny	6	1	Keywords	keyword	NNS
work_clhxj3r6pndirghkema3cc6pny	6	2	:	:	:
work_clhxj3r6pndirghkema3cc6pny	6	3	Sickle	sickle	NN
work_clhxj3r6pndirghkema3cc6pny	6	4	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	6	5	disease	disease	NN
work_clhxj3r6pndirghkema3cc6pny	6	6	;	;	:
work_clhxj3r6pndirghkema3cc6pny	6	7	Pain	pain	NN
work_clhxj3r6pndirghkema3cc6pny	6	8	;	;	:
work_clhxj3r6pndirghkema3cc6pny	6	9	Individualized	individualized	JJ
work_clhxj3r6pndirghkema3cc6pny	6	10	treatment	treatment	NN
work_clhxj3r6pndirghkema3cc6pny	6	11	;	;	:
work_clhxj3r6pndirghkema3cc6pny	6	12	Per-	per-	XX
work_clhxj3r6pndirghkema3cc6pny	6	13	sonalized	sonalize	VBD
work_clhxj3r6pndirghkema3cc6pny	6	14	medicine	medicine	NN
work_clhxj3r6pndirghkema3cc6pny	6	15	;	;	:
work_clhxj3r6pndirghkema3cc6pny	6	16	Precision	precision	NN
work_clhxj3r6pndirghkema3cc6pny	6	17	medicine	medicine	NN
work_clhxj3r6pndirghkema3cc6pny	6	18	Introduction	introduction	NN
work_clhxj3r6pndirghkema3cc6pny	6	19	An	an	DT
work_clhxj3r6pndirghkema3cc6pny	6	20	infliction	infliction	NN
work_clhxj3r6pndirghkema3cc6pny	6	21	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	6	22	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	6	23	life	life	NN
work_clhxj3r6pndirghkema3cc6pny	6	24	expectancy	expectancy	NN
work_clhxj3r6pndirghkema3cc6pny	6	25	figure	figure	NN
work_clhxj3r6pndirghkema3cc6pny	6	26	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	6	27	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	6	28	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	6	29	sick-	sick-	NNP
work_clhxj3r6pndirghkema3cc6pny	6	30	le	le	NNP
work_clhxj3r6pndirghkema3cc6pny	6	31	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	6	32	disease	disease	NNP
work_clhxj3r6pndirghkema3cc6pny	6	33	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	6	34	SCD	SCD	NNP
work_clhxj3r6pndirghkema3cc6pny	6	35	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	6	36	occurred	occur	VBD
work_clhxj3r6pndirghkema3cc6pny	6	37	around	around	IN
work_clhxj3r6pndirghkema3cc6pny	6	38	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	6	39	middle	middle	NN
work_clhxj3r6pndirghkema3cc6pny	6	40	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	6	41	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	6	42	1970s	1970	NNS
work_clhxj3r6pndirghkema3cc6pny	6	43	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	6	44	Fig	fig	NN
work_clhxj3r6pndirghkema3cc6pny	6	45	.	.	.
work_clhxj3r6pndirghkema3cc6pny	7	1	1	1	LS
work_clhxj3r6pndirghkema3cc6pny	7	2	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	7	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	8	1	This	this	DT
work_clhxj3r6pndirghkema3cc6pny	8	2	minimal	minimal	JJ
work_clhxj3r6pndirghkema3cc6pny	8	3	increase	increase	NN
work_clhxj3r6pndirghkema3cc6pny	8	4	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	8	5	life	life	NN
work_clhxj3r6pndirghkema3cc6pny	8	6	expectancy	expectancy	NN
work_clhxj3r6pndirghkema3cc6pny	8	7	coincided	coincide	VBD
work_clhxj3r6pndirghkema3cc6pny	8	8	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	8	9	my	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	8	10	appointment	appointment	NN
work_clhxj3r6pndirghkema3cc6pny	8	11	at	at	IN
work_clhxj3r6pndirghkema3cc6pny	8	12	Thomas	Thomas	NNP
work_clhxj3r6pndirghkema3cc6pny	8	13	Jefferson	Jefferson	NNP
work_clhxj3r6pndirghkema3cc6pny	8	14	University	University	NNP
work_clhxj3r6pndirghkema3cc6pny	8	15	as	as	IN
work_clhxj3r6pndirghkema3cc6pny	8	16	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	8	17	Associate	Associate	NNP
work_clhxj3r6pndirghkema3cc6pny	8	18	Director	Director	NNP
work_clhxj3r6pndirghkema3cc6pny	8	19	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	8	20	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	8	21	newly	newly	RB
work_clhxj3r6pndirghkema3cc6pny	8	22	created	create	VBN
work_clhxj3r6pndirghkema3cc6pny	8	23	adult	adult	NN
work_clhxj3r6pndirghkema3cc6pny	8	24	sickle	sickle	NN
work_clhxj3r6pndirghkema3cc6pny	8	25	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	8	26	center	center	NN
work_clhxj3r6pndirghkema3cc6pny	8	27	.	.	.
work_clhxj3r6pndirghkema3cc6pny	9	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	9	2	number	number	NN
work_clhxj3r6pndirghkema3cc6pny	9	3	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	9	4	adults	adult	NNS
work_clhxj3r6pndirghkema3cc6pny	9	5	at	at	IN
work_clhxj3r6pndirghkema3cc6pny	9	6	that	that	DT
work_clhxj3r6pndirghkema3cc6pny	9	7	time	time	NN
work_clhxj3r6pndirghkema3cc6pny	9	8	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	9	9	small	small	JJ
work_clhxj3r6pndirghkema3cc6pny	9	10	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	9	11	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	9	12	transition	transition	NN
work_clhxj3r6pndirghkema3cc6pny	9	13	from	from	IN
work_clhxj3r6pndirghkema3cc6pny	9	14	pediatrics	pediatric	NNS
work_clhxj3r6pndirghkema3cc6pny	9	15	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	9	16	adult	adult	VB
work_clhxj3r6pndirghkema3cc6pny	9	17	programs	program	NNS
work_clhxj3r6pndirghkema3cc6pny	9	18	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	9	19	at	at	IN
work_clhxj3r6pndirghkema3cc6pny	9	20	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	9	21	age	age	NN
work_clhxj3r6pndirghkema3cc6pny	9	22	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	9	23	18	18	CD
work_clhxj3r6pndirghkema3cc6pny	9	24	years	year	NNS
work_clhxj3r6pndirghkema3cc6pny	9	25	.	.	.
work_clhxj3r6pndirghkema3cc6pny	10	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	10	2	trickle	trickle	NN
work_clhxj3r6pndirghkema3cc6pny	10	3	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	10	4	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	10	5	increased	increase	VBD
work_clhxj3r6pndirghkema3cc6pny	10	6	gradually	gradually	RB
work_clhxj3r6pndirghkema3cc6pny	10	7	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	10	8	we	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	10	9	were	be	VBD
work_clhxj3r6pndirghkema3cc6pny	10	10	faced	face	VBN
work_clhxj3r6pndirghkema3cc6pny	10	11	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	10	12	adolescent	adolescent	JJ
work_clhxj3r6pndirghkema3cc6pny	10	13	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	10	14	young	young	JJ
work_clhxj3r6pndirghkema3cc6pny	10	15	adult	adult	NN
work_clhxj3r6pndirghkema3cc6pny	10	16	African	african	JJ
work_clhxj3r6pndirghkema3cc6pny	10	17	American	american	JJ
work_clhxj3r6pndirghkema3cc6pny	10	18	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	10	19	who	who	WP
work_clhxj3r6pndirghkema3cc6pny	10	20	were	be	VBD
work_clhxj3r6pndirghkema3cc6pny	10	21	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	10	22	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	10	23	state	state	NN
work_clhxj3r6pndirghkema3cc6pny	10	24	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	10	25	confusion	confusion	NN
work_clhxj3r6pndirghkema3cc6pny	10	26	.	.	.
work_clhxj3r6pndirghkema3cc6pny	11	1	Stripped	strip	VBN
work_clhxj3r6pndirghkema3cc6pny	11	2	from	from	IN
work_clhxj3r6pndirghkema3cc6pny	11	3	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	11	4	protective	protective	JJ
work_clhxj3r6pndirghkema3cc6pny	11	5	sphere	sphere	NN
work_clhxj3r6pndirghkema3cc6pny	11	6	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	11	7	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	11	8	pediatric	pediatric	JJ
work_clhxj3r6pndirghkema3cc6pny	11	9	world	world	NN
work_clhxj3r6pndirghkema3cc6pny	11	10	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	11	11	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	11	12	empathy	empathy	NN
work_clhxj3r6pndirghkema3cc6pny	11	13	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	11	14	their	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	11	15	pediatric	pediatric	JJ
work_clhxj3r6pndirghkema3cc6pny	11	16	hematologists	hematologist	NNS
work_clhxj3r6pndirghkema3cc6pny	11	17	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	11	18	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	11	19	pediatric	pediatric	JJ
work_clhxj3r6pndirghkema3cc6pny	11	20	ancillary	ancillary	JJ
work_clhxj3r6pndirghkema3cc6pny	11	21	staff	staff	NN
work_clhxj3r6pndirghkema3cc6pny	11	22	,	,	,
work_clhxj3r6pndirghkema3cc6pny	11	23	they	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	11	24	were	be	VBD
work_clhxj3r6pndirghkema3cc6pny	11	25	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	11	26	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	11	27	state	state	NN
work_clhxj3r6pndirghkema3cc6pny	11	28	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	11	29	fear	fear	NN
work_clhxj3r6pndirghkema3cc6pny	11	30	,	,	,
work_clhxj3r6pndirghkema3cc6pny	11	31	anxiety	anxiety	NN
work_clhxj3r6pndirghkema3cc6pny	11	32	,	,	,
work_clhxj3r6pndirghkema3cc6pny	11	33	depression	depression	NN
work_clhxj3r6pndirghkema3cc6pny	11	34	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	11	35	,	,	,
work_clhxj3r6pndirghkema3cc6pny	11	36	worst	bad	JJS
work_clhxj3r6pndirghkema3cc6pny	11	37	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	11	38	all	all	DT
work_clhxj3r6pndirghkema3cc6pny	11	39	,	,	,
work_clhxj3r6pndirghkema3cc6pny	11	40	severe	severe	JJ
work_clhxj3r6pndirghkema3cc6pny	11	41	pain	pain	NN
work_clhxj3r6pndirghkema3cc6pny	11	42	.	.	.
work_clhxj3r6pndirghkema3cc6pny	12	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	12	2	world	world	NN
work_clhxj3r6pndirghkema3cc6pny	12	3	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	12	4	adults	adult	NNS
work_clhxj3r6pndirghkema3cc6pny	12	5	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	12	6	abject	abject	JJ
work_clhxj3r6pndirghkema3cc6pny	12	7	,	,	,
work_clhxj3r6pndirghkema3cc6pny	12	8	withdrawn	withdraw	VBN
work_clhxj3r6pndirghkema3cc6pny	12	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	12	10	busy	busy	JJ
work_clhxj3r6pndirghkema3cc6pny	12	11	,	,	,
work_clhxj3r6pndirghkema3cc6pny	12	12	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	12	13	status	status	NN
work_clhxj3r6pndirghkema3cc6pny	12	14	oriented	orient	VBN
work_clhxj3r6pndirghkema3cc6pny	12	15	.	.	.
work_clhxj3r6pndirghkema3cc6pny	13	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	13	2	fact	fact	NN
work_clhxj3r6pndirghkema3cc6pny	13	3	that	that	IN
work_clhxj3r6pndirghkema3cc6pny	13	4	most	most	JJS
work_clhxj3r6pndirghkema3cc6pny	13	5	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	13	6	were	be	VBD
work_clhxj3r6pndirghkema3cc6pny	13	7	barely	barely	RB
work_clhxj3r6pndirghkema3cc6pny	13	8	educated	educate	VBN
work_clhxj3r6pndirghkema3cc6pny	13	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	13	10	many	many	JJ
work_clhxj3r6pndirghkema3cc6pny	13	11	without	without	IN
work_clhxj3r6pndirghkema3cc6pny	13	12	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	13	13	high	high	JJ
work_clhxj3r6pndirghkema3cc6pny	13	14	school	school	NN
work_clhxj3r6pndirghkema3cc6pny	13	15	degree	degree	NN
work_clhxj3r6pndirghkema3cc6pny	13	16	,	,	,
work_clhxj3r6pndirghkema3cc6pny	13	17	unemployed	unemployed	JJ
work_clhxj3r6pndirghkema3cc6pny	13	18	,	,	,
work_clhxj3r6pndirghkema3cc6pny	13	19	mediocre	mediocre	JJ
work_clhxj3r6pndirghkema3cc6pny	13	20	health	health	NN
work_clhxj3r6pndirghkema3cc6pny	13	21	coverage	coverage	NN
work_clhxj3r6pndirghkema3cc6pny	13	22	,	,	,
work_clhxj3r6pndirghkema3cc6pny	13	23	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	13	24	dysfunctional	dysfunctional	JJ
work_clhxj3r6pndirghkema3cc6pny	13	25	family	family	NN
work_clhxj3r6pndirghkema3cc6pny	13	26	structure	structure	NN
work_clhxj3r6pndirghkema3cc6pny	13	27	conferred	confer	VBD
work_clhxj3r6pndirghkema3cc6pny	13	28	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	13	29	logarithmic	logarithmic	JJ
work_clhxj3r6pndirghkema3cc6pny	13	30	dimension	dimension	NN
work_clhxj3r6pndirghkema3cc6pny	13	31	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	13	32	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	13	33	problem	problem	NN
work_clhxj3r6pndirghkema3cc6pny	13	34	.	.	.
work_clhxj3r6pndirghkema3cc6pny	14	1	Their	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	14	2	main	main	JJ
work_clhxj3r6pndirghkema3cc6pny	14	3	hope	hope	NN
work_clhxj3r6pndirghkema3cc6pny	14	4	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	14	5	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	14	6	have	have	VB
work_clhxj3r6pndirghkema3cc6pny	14	7	pain	pain	NN
work_clhxj3r6pndirghkema3cc6pny	14	8	relief	relief	NN
work_clhxj3r6pndirghkema3cc6pny	14	9	.	.	.
work_clhxj3r6pndirghkema3cc6pny	15	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	15	2	steady	steady	JJ
work_clhxj3r6pndirghkema3cc6pny	15	3	stream	stream	NN
work_clhxj3r6pndirghkema3cc6pny	15	4	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	15	5	admissions	admission	NNS
work_clhxj3r6pndirghkema3cc6pny	15	6	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	15	7	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	15	8	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	15	9	acute	acute	JJ
work_clhxj3r6pndirghkema3cc6pny	15	10	painful	painful	JJ
work_clhxj3r6pndirghkema3cc6pny	15	11	vaso	vaso	JJ
work_clhxj3r6pndirghkema3cc6pny	15	12	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	15	13	occlusive	occlusive	NN
work_clhxj3r6pndirghkema3cc6pny	15	14	crises	crisis	NNS
work_clhxj3r6pndirghkema3cc6pny	15	15	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	15	16	VOCs	VOCs	NNP
work_clhxj3r6pndirghkema3cc6pny	15	17	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	15	18	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	15	19	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	15	20	emergency	emergency	NN
work_clhxj3r6pndirghkema3cc6pny	15	21	depart-	depart-	VBZ
work_clhxj3r6pndirghkema3cc6pny	15	22	ment	ment	NNP
work_clhxj3r6pndirghkema3cc6pny	15	23	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	15	24	ED	ED	NNP
work_clhxj3r6pndirghkema3cc6pny	15	25	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	15	26	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	15	27	hospital	hospital	NN
work_clhxj3r6pndirghkema3cc6pny	15	28	were	be	VBD
work_clhxj3r6pndirghkema3cc6pny	15	29	not	not	RB
work_clhxj3r6pndirghkema3cc6pny	15	30	welcome	welcome	JJ
work_clhxj3r6pndirghkema3cc6pny	15	31	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	15	32	most	most	JJS
work_clhxj3r6pndirghkema3cc6pny	15	33	providers	provider	NNS
work_clhxj3r6pndirghkema3cc6pny	15	34	,	,	,
work_clhxj3r6pndirghkema3cc6pny	15	35	hospital	hospital	NNP
work_clhxj3r6pndirghkema3cc6pny	15	36	administration	administration	NNP
work_clhxj3r6pndirghkema3cc6pny	15	37	,	,	,
work_clhxj3r6pndirghkema3cc6pny	15	38	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	15	39	house	house	NN
work_clhxj3r6pndirghkema3cc6pny	15	40	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	15	41	nursing	nursing	NN
work_clhxj3r6pndirghkema3cc6pny	15	42	staffs	staff	NNS
work_clhxj3r6pndirghkema3cc6pny	15	43	.	.	.
work_clhxj3r6pndirghkema3cc6pny	16	1	There	there	EX
work_clhxj3r6pndirghkema3cc6pny	16	2	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	16	3	subtle	subtle	JJ
work_clhxj3r6pndirghkema3cc6pny	16	4	resentment	resentment	NN
work_clhxj3r6pndirghkema3cc6pny	16	5	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	16	6	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	16	7	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	16	8	that	that	WDT
work_clhxj3r6pndirghkema3cc6pny	16	9	sometimes	sometimes	RB
work_clhxj3r6pndirghkema3cc6pny	16	10	extended	extend	VBD
work_clhxj3r6pndirghkema3cc6pny	16	11	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	16	12	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	16	13	hematologists	hematologist	NNS
work_clhxj3r6pndirghkema3cc6pny	16	14	who	who	WP
work_clhxj3r6pndirghkema3cc6pny	16	15	showed	show	VBD
work_clhxj3r6pndirghkema3cc6pny	16	16	compassion	compassion	NN
work_clhxj3r6pndirghkema3cc6pny	16	17	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	16	18	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	16	19	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	16	20	.	.	.
work_clhxj3r6pndirghkema3cc6pny	17	1	Soon	soon	RB
work_clhxj3r6pndirghkema3cc6pny	17	2	labels	label	NNS
work_clhxj3r6pndirghkema3cc6pny	17	3	such	such	JJ
work_clhxj3r6pndirghkema3cc6pny	17	4	as	as	IN
work_clhxj3r6pndirghkema3cc6pny	17	5	drug	drug	NN
work_clhxj3r6pndirghkema3cc6pny	17	6	addicts	addict	NNS
work_clhxj3r6pndirghkema3cc6pny	17	7	,	,	,
work_clhxj3r6pndirghkema3cc6pny	17	8	drug	drug	NN
work_clhxj3r6pndirghkema3cc6pny	17	9	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	17	10	seeking	seek	VBG
work_clhxj3r6pndirghkema3cc6pny	17	11	behavior	behavior	NN
work_clhxj3r6pndirghkema3cc6pny	17	12	,	,	,
work_clhxj3r6pndirghkema3cc6pny	17	13	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	17	14	hospital	hospital	NN
work_clhxj3r6pndirghkema3cc6pny	17	15	hopping	hopping	NN
work_clhxj3r6pndirghkema3cc6pny	17	16	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	17	17	frequent	frequent	JJ
work_clhxj3r6pndirghkema3cc6pny	17	18	flyer	flyer	NN
work_clhxj3r6pndirghkema3cc6pny	17	19	emerged	emerge	VBD
work_clhxj3r6pndirghkema3cc6pny	17	20	.	.	.
work_clhxj3r6pndirghkema3cc6pny	18	1	Listening	listen	VBG
work_clhxj3r6pndirghkema3cc6pny	18	2	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	18	3	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	18	4	believing	believe	VBG
work_clhxj3r6pndirghkema3cc6pny	18	5	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	18	6	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	18	7	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	18	8	keeping	keep	VBG
work_clhxj3r6pndirghkema3cc6pny	18	9	de-	de-	RB
work_clhxj3r6pndirghkema3cc6pny	18	10	tailed	tailed	JJ
work_clhxj3r6pndirghkema3cc6pny	18	11	records	record	NNS
work_clhxj3r6pndirghkema3cc6pny	18	12	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	18	13	ED	ed	NN
work_clhxj3r6pndirghkema3cc6pny	18	14	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	18	15	hospital	hospital	NN
work_clhxj3r6pndirghkema3cc6pny	18	16	admissions	admission	NNS
work_clhxj3r6pndirghkema3cc6pny	18	17	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	18	18	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	18	19	analge-	analge-	JJ
work_clhxj3r6pndirghkema3cc6pny	18	20	sics	sic	NNS
work_clhxj3r6pndirghkema3cc6pny	18	21	prescribed	prescribe	VBN
work_clhxj3r6pndirghkema3cc6pny	18	22	,	,	,
work_clhxj3r6pndirghkema3cc6pny	18	23	revealed	reveal	VBD
work_clhxj3r6pndirghkema3cc6pny	18	24	that	that	IN
work_clhxj3r6pndirghkema3cc6pny	18	25	most	most	JJS
work_clhxj3r6pndirghkema3cc6pny	18	26	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	18	27	genuinely	genuinely	RB
work_clhxj3r6pndirghkema3cc6pny	18	28	do	do	VBP
work_clhxj3r6pndirghkema3cc6pny	18	29	not	not	RB
work_clhxj3r6pndirghkema3cc6pny	18	30	respond	respond	VB
work_clhxj3r6pndirghkema3cc6pny	18	31	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	18	32	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	18	33	certain	certain	JJ
work_clhxj3r6pndirghkema3cc6pny	18	34	analgesic	analgesic	NN
work_clhxj3r6pndirghkema3cc6pny	18	35	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	18	36	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	18	37	certain	certain	JJ
work_clhxj3r6pndirghkema3cc6pny	18	38	dose	dose	NN
work_clhxj3r6pndirghkema3cc6pny	18	39	.	.	.
work_clhxj3r6pndirghkema3cc6pny	19	1	Increasing	increase	VBG
work_clhxj3r6pndirghkema3cc6pny	19	2	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	19	3	doses	dose	NNS
work_clhxj3r6pndirghkema3cc6pny	19	4	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	19	5	an	an	DT
work_clhxj3r6pndirghkema3cc6pny	19	6	analgesic	analgesic	JJ
work_clhxj3r6pndirghkema3cc6pny	19	7	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	19	8	switching	switch	VBG
work_clhxj3r6pndirghkema3cc6pny	19	9	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	19	10	another	another	DT
work_clhxj3r6pndirghkema3cc6pny	19	11	drug	drug	NN
work_clhxj3r6pndirghkema3cc6pny	19	12	solved	solve	VBD
work_clhxj3r6pndirghkema3cc6pny	19	13	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	19	14	problem	problem	NN
work_clhxj3r6pndirghkema3cc6pny	19	15	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	19	16	most	most	JJS
work_clhxj3r6pndirghkema3cc6pny	19	17	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	19	18	.	.	.
work_clhxj3r6pndirghkema3cc6pny	20	1	Soon	soon	RB
work_clhxj3r6pndirghkema3cc6pny	20	2	it	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	20	3	became	become	VBD
work_clhxj3r6pndirghkema3cc6pny	20	4	obvious	obvious	JJ
work_clhxj3r6pndirghkema3cc6pny	20	5	that	that	IN
work_clhxj3r6pndirghkema3cc6pny	20	6	man-	man-	MD
work_clhxj3r6pndirghkema3cc6pny	20	7	agement	agement	NN
work_clhxj3r6pndirghkema3cc6pny	20	8	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	20	9	sickle	sickle	NN
work_clhxj3r6pndirghkema3cc6pny	20	10	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	20	11	pain	pain	NN
work_clhxj3r6pndirghkema3cc6pny	20	12	should	should	MD
work_clhxj3r6pndirghkema3cc6pny	20	13	be	be	VB
work_clhxj3r6pndirghkema3cc6pny	20	14	individualized	individualize	VBN
work_clhxj3r6pndirghkema3cc6pny	20	15	.	.	.
work_clhxj3r6pndirghkema3cc6pny	21	1	Accordingly	accordingly	RB
work_clhxj3r6pndirghkema3cc6pny	21	2	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	21	3	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	21	4	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	21	5	approval	approval	NN
work_clhxj3r6pndirghkema3cc6pny	21	6	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	21	7	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	21	8	institutional	institutional	JJ
work_clhxj3r6pndirghkema3cc6pny	21	9	re-	re-	NNP
work_clhxj3r6pndirghkema3cc6pny	21	10	view	view	NNP
work_clhxj3r6pndirghkema3cc6pny	21	11	board	board	NNP
work_clhxj3r6pndirghkema3cc6pny	21	12	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	21	13	IRB	IRB	NNP
work_clhxj3r6pndirghkema3cc6pny	21	14	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	21	15	,	,	,
work_clhxj3r6pndirghkema3cc6pny	21	16	I	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	21	17	issued	issue	VBD
work_clhxj3r6pndirghkema3cc6pny	21	18	an	an	DT
work_clhxj3r6pndirghkema3cc6pny	21	19	identification	identification	NN
work_clhxj3r6pndirghkema3cc6pny	21	20	wallet	wallet	NN
work_clhxj3r6pndirghkema3cc6pny	21	21	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	21	22	sized	sized	JJ
work_clhxj3r6pndirghkema3cc6pny	21	23	,	,	,
work_clhxj3r6pndirghkema3cc6pny	21	24	plas-	plas-	NNP
work_clhxj3r6pndirghkema3cc6pny	21	25	ticized	ticize	VBD
work_clhxj3r6pndirghkema3cc6pny	21	26	card	card	NN
work_clhxj3r6pndirghkema3cc6pny	21	27	that	that	WDT
work_clhxj3r6pndirghkema3cc6pny	21	28	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	21	29	carried	carry	VBN
work_clhxj3r6pndirghkema3cc6pny	21	30	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	21	31	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	21	32	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	21	33	presented	present	VBD
work_clhxj3r6pndirghkema3cc6pny	21	34	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	21	35	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	21	36	provider	provider	NN
work_clhxj3r6pndirghkema3cc6pny	21	37	treating	treat	VBG
work_clhxj3r6pndirghkema3cc6pny	21	38	their	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	21	39	VOC	voc	NN
work_clhxj3r6pndirghkema3cc6pny	21	40	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	21	41	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	21	42	ED	ED	NNP
work_clhxj3r6pndirghkema3cc6pny	21	43	,	,	,
work_clhxj3r6pndirghkema3cc6pny	21	44	hospital	hospital	NN
work_clhxj3r6pndirghkema3cc6pny	21	45	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	21	46	any	any	DT
work_clhxj3r6pndirghkema3cc6pny	21	47	other	other	JJ
work_clhxj3r6pndirghkema3cc6pny	21	48	medical	medical	JJ
work_clhxj3r6pndirghkema3cc6pny	21	49	facility	facility	NN
work_clhxj3r6pndirghkema3cc6pny	21	50	.	.	.
work_clhxj3r6pndirghkema3cc6pny	22	1	Information	information	NN
work_clhxj3r6pndirghkema3cc6pny	22	2	printed	print	VBN
work_clhxj3r6pndirghkema3cc6pny	22	3	on	on	IN
work_clhxj3r6pndirghkema3cc6pny	22	4	both	both	DT
work_clhxj3r6pndirghkema3cc6pny	22	5	sides	side	NNS
work_clhxj3r6pndirghkema3cc6pny	22	6	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	22	7	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	22	8	card	card	NN
work_clhxj3r6pndirghkema3cc6pny	22	9	included	include	VBD
work_clhxj3r6pndirghkema3cc6pny	22	10	:	:	:
work_clhxj3r6pndirghkema3cc6pny	22	11	1	1	LS
work_clhxj3r6pndirghkema3cc6pny	22	12	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	22	13	demographic	demographic	JJ
work_clhxj3r6pndirghkema3cc6pny	22	14	data	datum	NNS
work_clhxj3r6pndirghkema3cc6pny	22	15	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	22	16	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	22	17	recent	recent	JJ
work_clhxj3r6pndirghkema3cc6pny	22	18	photograph	photograph	NN
work_clhxj3r6pndirghkema3cc6pny	22	19	;	;	:
work_clhxj3r6pndirghkema3cc6pny	22	20	2	2	LS
work_clhxj3r6pndirghkema3cc6pny	22	21	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	22	22	he-	he-	POS
work_clhxj3r6pndirghkema3cc6pny	22	23	matological	matological	JJ
work_clhxj3r6pndirghkema3cc6pny	22	24	data	datum	NNS
work_clhxj3r6pndirghkema3cc6pny	22	25	including	include	VBG
work_clhxj3r6pndirghkema3cc6pny	22	26	reticulocyte	reticulocyte	NNP
work_clhxj3r6pndirghkema3cc6pny	22	27	count	count	NN
work_clhxj3r6pndirghkema3cc6pny	22	28	;	;	:
work_clhxj3r6pndirghkema3cc6pny	22	29	3	3	LS
work_clhxj3r6pndirghkema3cc6pny	22	30	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	22	31	medical	medical	JJ
work_clhxj3r6pndirghkema3cc6pny	22	32	data	datum	NNS
work_clhxj3r6pndirghkema3cc6pny	22	33	including	include	VBG
work_clhxj3r6pndirghkema3cc6pny	22	34	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	22	35	type	type	NN
work_clhxj3r6pndirghkema3cc6pny	22	36	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	22	37	SCD	SCD	NNP
work_clhxj3r6pndirghkema3cc6pny	22	38	,	,	,
work_clhxj3r6pndirghkema3cc6pny	22	39	its	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	22	40	complications	complication	NNS
work_clhxj3r6pndirghkema3cc6pny	22	41	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	22	42	co	co	JJ
work_clhxj3r6pndirghkema3cc6pny	22	43	-	-	JJ
work_clhxj3r6pndirghkema3cc6pny	22	44	morbid-	morbid-	JJ
work_clhxj3r6pndirghkema3cc6pny	22	45	ities	itie	NNS
work_clhxj3r6pndirghkema3cc6pny	22	46	if	if	IN
work_clhxj3r6pndirghkema3cc6pny	22	47	present	present	JJ
work_clhxj3r6pndirghkema3cc6pny	22	48	;	;	:
work_clhxj3r6pndirghkema3cc6pny	22	49	4	4	LS
work_clhxj3r6pndirghkema3cc6pny	22	50	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	22	51	all	all	DT
work_clhxj3r6pndirghkema3cc6pny	22	52	medications	medication	NNS
work_clhxj3r6pndirghkema3cc6pny	22	53	being	be	VBG
work_clhxj3r6pndirghkema3cc6pny	22	54	taken	take	VBN
work_clhxj3r6pndirghkema3cc6pny	22	55	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	22	56	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	22	57	patient	patient	NN
work_clhxj3r6pndirghkema3cc6pny	22	58	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	22	59	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	22	60	recommended	recommend	VBN
work_clhxj3r6pndirghkema3cc6pny	22	61	treatment	treatment	NN
work_clhxj3r6pndirghkema3cc6pny	22	62	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	22	63	VOCs	voc	NNS
work_clhxj3r6pndirghkema3cc6pny	22	64	including	include	VBG
work_clhxj3r6pndirghkema3cc6pny	22	65	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	22	66	name	name	NN
work_clhxj3r6pndirghkema3cc6pny	22	67	,	,	,
work_clhxj3r6pndirghkema3cc6pny	22	68	dose	dose	VB
work_clhxj3r6pndirghkema3cc6pny	22	69	,	,	,
work_clhxj3r6pndirghkema3cc6pny	22	70	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	22	71	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	22	72	route	route	NN
work_clhxj3r6pndirghkema3cc6pny	22	73	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	22	74	administration	administration	NN
work_clhxj3r6pndirghkema3cc6pny	22	75	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	22	76	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	22	77	analgesics	analgesic	NNS
work_clhxj3r6pndirghkema3cc6pny	22	78	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	22	79	ques-	ques-	NNP
work_clhxj3r6pndirghkema3cc6pny	22	80	tion	tion	NN
work_clhxj3r6pndirghkema3cc6pny	22	81	;	;	:
work_clhxj3r6pndirghkema3cc6pny	22	82	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	22	83	5	5	LS
work_clhxj3r6pndirghkema3cc6pny	22	84	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	22	85	my	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	22	86	name	name	NN
work_clhxj3r6pndirghkema3cc6pny	22	87	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	22	88	contact	contact	NN
work_clhxj3r6pndirghkema3cc6pny	22	89	information	information	NN
work_clhxj3r6pndirghkema3cc6pny	22	90	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	22	91	answering	answer	VBG
work_clhxj3r6pndirghkema3cc6pny	22	92	questions	question	NNS
work_clhxj3r6pndirghkema3cc6pny	22	93	if	if	IN
work_clhxj3r6pndirghkema3cc6pny	22	94	needed	need	VBN
work_clhxj3r6pndirghkema3cc6pny	22	95	.	.	.
work_clhxj3r6pndirghkema3cc6pny	23	1	It	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	23	2	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	23	3	not	not	RB
work_clhxj3r6pndirghkema3cc6pny	23	4	expensive	expensive	JJ
work_clhxj3r6pndirghkema3cc6pny	23	5	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	23	6	issue	issue	VB
work_clhxj3r6pndirghkema3cc6pny	23	7	these	these	DT
work_clhxj3r6pndirghkema3cc6pny	23	8	cards	card	NNS
work_clhxj3r6pndirghkema3cc6pny	23	9	.	.	.
work_clhxj3r6pndirghkema3cc6pny	24	1	A	a	DT
work_clhxj3r6pndirghkema3cc6pny	24	2	Polaroid	Polaroid	NNP
work_clhxj3r6pndirghkema3cc6pny	24	3	camera	camera	NN
work_clhxj3r6pndirghkema3cc6pny	24	4	available	available	JJ
work_clhxj3r6pndirghkema3cc6pny	24	5	at	at	IN
work_clhxj3r6pndirghkema3cc6pny	24	6	that	that	DT
work_clhxj3r6pndirghkema3cc6pny	24	7	time	time	NN
work_clhxj3r6pndirghkema3cc6pny	24	8	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	24	9	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	24	10	laminator	laminator	NN
work_clhxj3r6pndirghkema3cc6pny	24	11	were	be	VBD
work_clhxj3r6pndirghkema3cc6pny	24	12	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	24	13	only	only	JJ
work_clhxj3r6pndirghkema3cc6pny	24	14	equipments	equipment	NNS
work_clhxj3r6pndirghkema3cc6pny	24	15	needed	need	VBN
work_clhxj3r6pndirghkema3cc6pny	24	16	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	24	17	issue	issue	VB
work_clhxj3r6pndirghkema3cc6pny	24	18	these	these	DT
work_clhxj3r6pndirghkema3cc6pny	24	19	cards	card	NNS
work_clhxj3r6pndirghkema3cc6pny	24	20	.	.	.
work_clhxj3r6pndirghkema3cc6pny	25	1	Information	information	NN
work_clhxj3r6pndirghkema3cc6pny	25	2	on	on	IN
work_clhxj3r6pndirghkema3cc6pny	25	3	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	25	4	card	card	NN
work_clhxj3r6pndirghkema3cc6pny	25	5	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	25	6	revised	revise	VBN
work_clhxj3r6pndirghkema3cc6pny	25	7	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	25	8	updated	update	VBN
work_clhxj3r6pndirghkema3cc6pny	25	9	annually	annually	RB
work_clhxj3r6pndirghkema3cc6pny	25	10	.	.	.
work_clhxj3r6pndirghkema3cc6pny	26	1	Details	detail	NNS
work_clhxj3r6pndirghkema3cc6pny	26	2	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	26	3	this	this	DT
work_clhxj3r6pndirghkema3cc6pny	26	4	endeavor	endeavor	NN
work_clhxj3r6pndirghkema3cc6pny	26	5	were	be	VBD
work_clhxj3r6pndirghkema3cc6pny	26	6	published	publish	VBN
work_clhxj3r6pndirghkema3cc6pny	26	7	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	26	8	1990	1990	CD
work_clhxj3r6pndirghkema3cc6pny	26	9	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	26	10	1	1	CD
work_clhxj3r6pndirghkema3cc6pny	26	11	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	26	12	.	.	.
work_clhxj3r6pndirghkema3cc6pny	27	1	With	with	IN
work_clhxj3r6pndirghkema3cc6pny	27	2	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	27	3	advent	advent	NN
work_clhxj3r6pndirghkema3cc6pny	27	4	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	27	5	com-	com-	NN
work_clhxj3r6pndirghkema3cc6pny	27	6	puterization	puterization	NN
work_clhxj3r6pndirghkema3cc6pny	27	7	later	later	RB
work_clhxj3r6pndirghkema3cc6pny	27	8	on	on	RB
work_clhxj3r6pndirghkema3cc6pny	27	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	27	10	information	information	NN
work_clhxj3r6pndirghkema3cc6pny	27	11	on	on	IN
work_clhxj3r6pndirghkema3cc6pny	27	12	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	27	13	card	card	NN
work_clhxj3r6pndirghkema3cc6pny	27	14	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	27	15	computer-	computer-	NN
work_clhxj3r6pndirghkema3cc6pny	27	16	ized	ize	VBN
work_clhxj3r6pndirghkema3cc6pny	27	17	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	27	18	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	27	19	printed	print	VBN
work_clhxj3r6pndirghkema3cc6pny	27	20	copy	copy	NN
work_clhxj3r6pndirghkema3cc6pny	27	21	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	27	22	given	give	VBN
work_clhxj3r6pndirghkema3cc6pny	27	23	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	27	24	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	27	25	patient	patient	NN
work_clhxj3r6pndirghkema3cc6pny	27	26	.	.	.
work_clhxj3r6pndirghkema3cc6pny	28	1	Reactions	reaction	NNS
work_clhxj3r6pndirghkema3cc6pny	28	2	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	28	3	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	28	4	implementation	implementation	NN
work_clhxj3r6pndirghkema3cc6pny	28	5	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	28	6	this	this	DT
work_clhxj3r6pndirghkema3cc6pny	28	7	card	card	NN
work_clhxj3r6pndirghkema3cc6pny	28	8	were	be	VBD
work_clhxj3r6pndirghkema3cc6pny	28	9	mixed	mixed	JJ
work_clhxj3r6pndirghkema3cc6pny	28	10	.	.	.
work_clhxj3r6pndirghkema3cc6pny	29	1	Patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	29	2	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	29	3	their	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	29	4	families	family	NNS
work_clhxj3r6pndirghkema3cc6pny	29	5	loved	love	VBD
work_clhxj3r6pndirghkema3cc6pny	29	6	it	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	29	7	.	.	.
work_clhxj3r6pndirghkema3cc6pny	30	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	30	2	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	30	3	were	be	VBD
work_clhxj3r6pndirghkema3cc6pny	30	4	very	very	RB
work_clhxj3r6pndirghkema3cc6pny	30	5	compliant	compliant	JJ
work_clhxj3r6pndirghkema3cc6pny	30	6	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	30	7	carrying	carry	VBG
work_clhxj3r6pndirghkema3cc6pny	30	8	it	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	30	9	as	as	RB
work_clhxj3r6pndirghkema3cc6pny	30	10	faithfully	faithfully	RB
work_clhxj3r6pndirghkema3cc6pny	30	11	as	as	IN
work_clhxj3r6pndirghkema3cc6pny	30	12	they	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	30	13	carry	carry	VBP
work_clhxj3r6pndirghkema3cc6pny	30	14	their	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	30	15	medical	medical	JJ
work_clhxj3r6pndirghkema3cc6pny	30	16	cards	card	NNS
work_clhxj3r6pndirghkema3cc6pny	30	17	.	.	.
work_clhxj3r6pndirghkema3cc6pny	31	1	Some	some	DT
work_clhxj3r6pndirghkema3cc6pny	31	2	providers	provider	NNS
work_clhxj3r6pndirghkema3cc6pny	31	3	liked	like	VBD
work_clhxj3r6pndirghkema3cc6pny	31	4	it	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	31	5	very	very	RB
work_clhxj3r6pndirghkema3cc6pny	31	6	much	much	RB
work_clhxj3r6pndirghkema3cc6pny	31	7	because	because	IN
work_clhxj3r6pndirghkema3cc6pny	31	8	it	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	31	9	facilitated	facilitate	VBD
work_clhxj3r6pndirghkema3cc6pny	31	10	having	have	VBG
work_clhxj3r6pndirghkema3cc6pny	31	11	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	31	12	concise	concise	JJ
work_clhxj3r6pndirghkema3cc6pny	31	13	history	history	NN
work_clhxj3r6pndirghkema3cc6pny	31	14	about	about	IN
work_clhxj3r6pndirghkema3cc6pny	31	15	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	31	16	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	31	17	.	.	.
work_clhxj3r6pndirghkema3cc6pny	32	1	Others	other	NNS
work_clhxj3r6pndirghkema3cc6pny	32	2	denounced	denounce	VBD
work_clhxj3r6pndirghkema3cc6pny	32	3	it	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	32	4	as	as	IN
work_clhxj3r6pndirghkema3cc6pny	32	5	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	32	6	gimmick	gimmick	NN
work_clhxj3r6pndirghkema3cc6pny	32	7	that	that	WDT
work_clhxj3r6pndirghkema3cc6pny	32	8	would	would	MD
work_clhxj3r6pndirghkema3cc6pny	32	9	allow	allow	VB
work_clhxj3r6pndirghkema3cc6pny	32	10	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	32	11	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	32	12	abuse	abuse	VB
work_clhxj3r6pndirghkema3cc6pny	32	13	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	32	14	system	system	NN
work_clhxj3r6pndirghkema3cc6pny	32	15	.	.	.
work_clhxj3r6pndirghkema3cc6pny	33	1	Pharmacology	Pharmacology	NNP
work_clhxj3r6pndirghkema3cc6pny	33	2	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	33	3	Opioids	Opioids	NNP
work_clhxj3r6pndirghkema3cc6pny	33	4	While	while	IN
work_clhxj3r6pndirghkema3cc6pny	33	5	this	this	DT
work_clhxj3r6pndirghkema3cc6pny	33	6	controversy	controversy	NN
work_clhxj3r6pndirghkema3cc6pny	33	7	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	33	8	brewing	brew	VBG
work_clhxj3r6pndirghkema3cc6pny	33	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	33	10	interesting	interesting	JJ
work_clhxj3r6pndirghkema3cc6pny	33	11	developments	development	NNS
work_clhxj3r6pndirghkema3cc6pny	33	12	Manuscript	Manuscript	NNP
work_clhxj3r6pndirghkema3cc6pny	33	13	accepted	accept	VBN
work_clhxj3r6pndirghkema3cc6pny	33	14	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	33	15	publication	publication	NN
work_clhxj3r6pndirghkema3cc6pny	33	16	March	March	NNP
work_clhxj3r6pndirghkema3cc6pny	33	17	03	03	CD
work_clhxj3r6pndirghkema3cc6pny	33	18	,	,	,
work_clhxj3r6pndirghkema3cc6pny	33	19	2016	2016	CD
work_clhxj3r6pndirghkema3cc6pny	33	20	Cardeza	Cardeza	NNP
work_clhxj3r6pndirghkema3cc6pny	33	21	Foundation	Foundation	NNP
work_clhxj3r6pndirghkema3cc6pny	33	22	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	33	23	Hematologic	Hematologic	NNP
work_clhxj3r6pndirghkema3cc6pny	33	24	Research	Research	NNP
work_clhxj3r6pndirghkema3cc6pny	33	25	,	,	,
work_clhxj3r6pndirghkema3cc6pny	33	26	Department	Department	NNP
work_clhxj3r6pndirghkema3cc6pny	33	27	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	33	28	Medicine	Medicine	NNP
work_clhxj3r6pndirghkema3cc6pny	33	29	,	,	,
work_clhxj3r6pndirghkema3cc6pny	33	30	Jefferson	Jefferson	NNP
work_clhxj3r6pndirghkema3cc6pny	33	31	Medical	Medical	NNP
work_clhxj3r6pndirghkema3cc6pny	33	32	College	College	NNP
work_clhxj3r6pndirghkema3cc6pny	33	33	,	,	,
work_clhxj3r6pndirghkema3cc6pny	33	34	Thomas	Thomas	NNP
work_clhxj3r6pndirghkema3cc6pny	33	35	Jefferson	Jefferson	NNP
work_clhxj3r6pndirghkema3cc6pny	33	36	University	University	NNP
work_clhxj3r6pndirghkema3cc6pny	33	37	,	,	,
work_clhxj3r6pndirghkema3cc6pny	33	38	Philadelphia	Philadelphia	NNP
work_clhxj3r6pndirghkema3cc6pny	33	39	,	,	,
work_clhxj3r6pndirghkema3cc6pny	33	40	PA	pa	NN
work_clhxj3r6pndirghkema3cc6pny	33	41	19107	19107	CD
work_clhxj3r6pndirghkema3cc6pny	33	42	,	,	,
work_clhxj3r6pndirghkema3cc6pny	33	43	USA	USA	NNP
work_clhxj3r6pndirghkema3cc6pny	33	44	.	.	.
work_clhxj3r6pndirghkema3cc6pny	34	1	Email	email	NN
work_clhxj3r6pndirghkema3cc6pny	34	2	:	:	:
work_clhxj3r6pndirghkema3cc6pny	34	3	samir.ballas@jefferson.edu	samir.ballas@jefferson.edu	ADD
work_clhxj3r6pndirghkema3cc6pny	34	4	doi	doi	FW
work_clhxj3r6pndirghkema3cc6pny	34	5	:	:	:
work_clhxj3r6pndirghkema3cc6pny	34	6	http://dx.doi.org/10.14740/jocmr2508w	http://dx.doi.org/10.14740/jocmr2508w	NNP
work_clhxj3r6pndirghkema3cc6pny	34	7	Articles	Articles	NNPS
work_clhxj3r6pndirghkema3cc6pny	34	8	©	©	NNP
work_clhxj3r6pndirghkema3cc6pny	34	9	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	34	10	authors	author	NNS
work_clhxj3r6pndirghkema3cc6pny	34	11	|	|	NNP
work_clhxj3r6pndirghkema3cc6pny	34	12	Journal	Journal	NNP
work_clhxj3r6pndirghkema3cc6pny	34	13	compilation	compilation	NN
work_clhxj3r6pndirghkema3cc6pny	34	14	©	©	NNP
work_clhxj3r6pndirghkema3cc6pny	34	15	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	34	16	Clin	Clin	NNP
work_clhxj3r6pndirghkema3cc6pny	34	17	Med	Med	NNP
work_clhxj3r6pndirghkema3cc6pny	34	18	Res	Res	NNP
work_clhxj3r6pndirghkema3cc6pny	34	19	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	34	20	Elmer	Elmer	NNP
work_clhxj3r6pndirghkema3cc6pny	34	21	Press	Press	NNP
work_clhxj3r6pndirghkema3cc6pny	34	22	Inc	Inc	NNP
work_clhxj3r6pndirghkema3cc6pny	34	23	™	™	CD
work_clhxj3r6pndirghkema3cc6pny	34	24	|	|	NNP
work_clhxj3r6pndirghkema3cc6pny	34	25	www.jocmr.org358	www.jocmr.org358	NNP
work_clhxj3r6pndirghkema3cc6pny	34	26	Management	Management	NNP
work_clhxj3r6pndirghkema3cc6pny	34	27	Evolution	Evolution	NNP
work_clhxj3r6pndirghkema3cc6pny	34	28	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	34	29	Sickle	Sickle	NNP
work_clhxj3r6pndirghkema3cc6pny	34	30	Cell	Cell	NNP
work_clhxj3r6pndirghkema3cc6pny	34	31	Pain	Pain	NNP
work_clhxj3r6pndirghkema3cc6pny	34	32	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	34	33	Clin	Clin	NNP
work_clhxj3r6pndirghkema3cc6pny	34	34	Med	Med	NNP
work_clhxj3r6pndirghkema3cc6pny	34	35	Res	Res	NNP
work_clhxj3r6pndirghkema3cc6pny	34	36	.	.	.
work_clhxj3r6pndirghkema3cc6pny	35	1	2016;8(5):357	2016;8(5):357	CD
work_clhxj3r6pndirghkema3cc6pny	35	2	-	-	NNP
work_clhxj3r6pndirghkema3cc6pny	35	3	360	360	CD
work_clhxj3r6pndirghkema3cc6pny	35	4	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	35	5	basic	basic	JJ
work_clhxj3r6pndirghkema3cc6pny	35	6	science	science	NN
work_clhxj3r6pndirghkema3cc6pny	35	7	were	be	VBD
work_clhxj3r6pndirghkema3cc6pny	35	8	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	35	9	progress	progress	NN
work_clhxj3r6pndirghkema3cc6pny	35	10	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	35	11	understand	understand	VB
work_clhxj3r6pndirghkema3cc6pny	35	12	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	35	13	pharmaco-	pharmaco-	JJ
work_clhxj3r6pndirghkema3cc6pny	35	14	dynamics	dynamic	NNS
work_clhxj3r6pndirghkema3cc6pny	35	15	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	35	16	pharmacokinetics	pharmacokinetic	NNS
work_clhxj3r6pndirghkema3cc6pny	35	17	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	35	18	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	35	19	.	.	.
work_clhxj3r6pndirghkema3cc6pny	36	1	Foremost	foremost	RB
work_clhxj3r6pndirghkema3cc6pny	36	2	among	among	IN
work_clhxj3r6pndirghkema3cc6pny	36	3	these	these	DT
work_clhxj3r6pndirghkema3cc6pny	36	4	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	36	5	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	36	6	mechanism	mechanism	NN
work_clhxj3r6pndirghkema3cc6pny	36	7	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	36	8	action	action	NN
work_clhxj3r6pndirghkema3cc6pny	36	9	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	36	10	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	36	11	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	36	12	relieving	relieve	VBG
work_clhxj3r6pndirghkema3cc6pny	36	13	pain	pain	NN
work_clhxj3r6pndirghkema3cc6pny	36	14	.	.	.
work_clhxj3r6pndirghkema3cc6pny	37	1	In	in	IN
work_clhxj3r6pndirghkema3cc6pny	37	2	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	37	3	1970s	1970	NNS
work_clhxj3r6pndirghkema3cc6pny	37	4	,	,	,
work_clhxj3r6pndirghkema3cc6pny	37	5	it	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	37	6	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	37	7	hypothesized	hypothesize	VBN
work_clhxj3r6pndirghkema3cc6pny	37	8	that	that	IN
work_clhxj3r6pndirghkema3cc6pny	37	9	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	37	10	have	have	VB
work_clhxj3r6pndirghkema3cc6pny	37	11	receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	37	12	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	37	13	bind	bind	VB
work_clhxj3r6pndirghkema3cc6pny	37	14	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	37	15	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	37	16	activate	activate	VB
work_clhxj3r6pndirghkema3cc6pny	37	17	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	37	18	order	order	NN
work_clhxj3r6pndirghkema3cc6pny	37	19	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	37	20	relieve	relieve	VB
work_clhxj3r6pndirghkema3cc6pny	37	21	pain	pain	NN
work_clhxj3r6pndirghkema3cc6pny	37	22	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	37	23	2	2	CD
work_clhxj3r6pndirghkema3cc6pny	37	24	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	37	25	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	37	26	blocking	block	VBG
work_clhxj3r6pndirghkema3cc6pny	37	27	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	37	28	minimizing	minimize	VBG
work_clhxj3r6pndirghkema3cc6pny	37	29	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	37	30	transmission	transmission	NN
work_clhxj3r6pndirghkema3cc6pny	37	31	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	37	32	painful	painful	JJ
work_clhxj3r6pndirghkema3cc6pny	37	33	stimuli	stimulus	NNS
work_clhxj3r6pndirghkema3cc6pny	37	34	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	37	35	raising	raise	VBG
work_clhxj3r6pndirghkema3cc6pny	37	36	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	37	37	pain	pain	NN
work_clhxj3r6pndirghkema3cc6pny	37	38	threshold	threshold	NN
work_clhxj3r6pndirghkema3cc6pny	37	39	.	.	.
work_clhxj3r6pndirghkema3cc6pny	38	1	It	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	38	2	did	do	VBD
work_clhxj3r6pndirghkema3cc6pny	38	3	not	not	RB
work_clhxj3r6pndirghkema3cc6pny	38	4	take	take	VB
work_clhxj3r6pndirghkema3cc6pny	38	5	long	long	RB
work_clhxj3r6pndirghkema3cc6pny	38	6	after	after	IN
work_clhxj3r6pndirghkema3cc6pny	38	7	that	that	DT
work_clhxj3r6pndirghkema3cc6pny	38	8	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	38	9	identify	identify	VB
work_clhxj3r6pndirghkema3cc6pny	38	10	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	38	11	as	as	IN
work_clhxj3r6pndirghkema3cc6pny	38	12	ligands	ligand	NNS
work_clhxj3r6pndirghkema3cc6pny	38	13	that	that	WDT
work_clhxj3r6pndirghkema3cc6pny	38	14	bind	bind	VBP
work_clhxj3r6pndirghkema3cc6pny	38	15	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	38	16	stereospecific	stereospecific	NN
work_clhxj3r6pndirghkema3cc6pny	38	17	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	38	18	saturable	saturable	JJ
work_clhxj3r6pndirghkema3cc6pny	38	19	re-	re-	JJ
work_clhxj3r6pndirghkema3cc6pny	38	20	ceptors	ceptor	NNS
work_clhxj3r6pndirghkema3cc6pny	38	21	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	38	22	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	38	23	central	central	JJ
work_clhxj3r6pndirghkema3cc6pny	38	24	nervous	nervous	JJ
work_clhxj3r6pndirghkema3cc6pny	38	25	system	system	NN
work_clhxj3r6pndirghkema3cc6pny	38	26	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	38	27	other	other	JJ
work_clhxj3r6pndirghkema3cc6pny	38	28	tissues	tissue	NNS
work_clhxj3r6pndirghkema3cc6pny	38	29	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	38	30	3	3	CD
work_clhxj3r6pndirghkema3cc6pny	38	31	,	,	,
work_clhxj3r6pndirghkema3cc6pny	38	32	4	4	CD
work_clhxj3r6pndirghkema3cc6pny	38	33	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	38	34	.	.	.
work_clhxj3r6pndirghkema3cc6pny	39	1	These	these	DT
work_clhxj3r6pndirghkema3cc6pny	39	2	receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	39	3	are	be	VBP
work_clhxj3r6pndirghkema3cc6pny	39	4	transmembranous	transmembranous	JJ
work_clhxj3r6pndirghkema3cc6pny	39	5	G	g	NN
work_clhxj3r6pndirghkema3cc6pny	39	6	proteins	protein	NNS
work_clhxj3r6pndirghkema3cc6pny	39	7	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	39	8	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	39	9	as	as	IN
work_clhxj3r6pndirghkema3cc6pny	39	10	ligands	ligand	NNS
work_clhxj3r6pndirghkema3cc6pny	39	11	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	39	12	5	5	CD
work_clhxj3r6pndirghkema3cc6pny	39	13	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	39	14	.	.	.
work_clhxj3r6pndirghkema3cc6pny	40	1	In	in	IN
work_clhxj3r6pndirghkema3cc6pny	40	2	addition	addition	NN
work_clhxj3r6pndirghkema3cc6pny	40	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	40	4	recent	recent	JJ
work_clhxj3r6pndirghkema3cc6pny	40	5	elegant	elegant	JJ
work_clhxj3r6pndirghkema3cc6pny	40	6	studies	study	NNS
work_clhxj3r6pndirghkema3cc6pny	40	7	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	40	8	6	6	CD
work_clhxj3r6pndirghkema3cc6pny	40	9	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	40	10	10	10	CD
work_clhxj3r6pndirghkema3cc6pny	40	11	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	40	12	have	have	VBP
work_clhxj3r6pndirghkema3cc6pny	40	13	revealed	reveal	VBN
work_clhxj3r6pndirghkema3cc6pny	40	14	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	40	15	helical	helical	JJ
work_clhxj3r6pndirghkema3cc6pny	40	16	structure	structure	NN
work_clhxj3r6pndirghkema3cc6pny	40	17	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	40	18	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	40	19	opioid	opioid	JJ
work_clhxj3r6pndirghkema3cc6pny	40	20	receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	40	21	,	,	,
work_clhxj3r6pndirghkema3cc6pny	40	22	which	which	WDT
work_clhxj3r6pndirghkema3cc6pny	40	23	forms	form	VBZ
work_clhxj3r6pndirghkema3cc6pny	40	24	pockets	pocket	NNS
work_clhxj3r6pndirghkema3cc6pny	40	25	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	40	26	which	which	WDT
work_clhxj3r6pndirghkema3cc6pny	40	27	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	40	28	corresponding	corresponding	JJ
work_clhxj3r6pndirghkema3cc6pny	40	29	opioid	opioid	NN
work_clhxj3r6pndirghkema3cc6pny	40	30	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	40	31	ligand	ligand	NNP
work_clhxj3r6pndirghkema3cc6pny	40	32	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	40	33	fits	fit	VBZ
work_clhxj3r6pndirghkema3cc6pny	40	34	snugly	snugly	RB
work_clhxj3r6pndirghkema3cc6pny	40	35	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	40	36	Fig	fig	NN
work_clhxj3r6pndirghkema3cc6pny	40	37	.	.	.
work_clhxj3r6pndirghkema3cc6pny	41	1	2a	2a	CD
work_clhxj3r6pndirghkema3cc6pny	41	2	,	,	,
work_clhxj3r6pndirghkema3cc6pny	41	3	b	b	NN
work_clhxj3r6pndirghkema3cc6pny	41	4	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	41	5	.	.	.
work_clhxj3r6pndirghkema3cc6pny	42	1	Receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	42	2	mediate	mediate	VBP
work_clhxj3r6pndirghkema3cc6pny	42	3	two	two	CD
work_clhxj3r6pndirghkema3cc6pny	42	4	major	major	JJ
work_clhxj3r6pndirghkema3cc6pny	42	5	functions	function	NNS
work_clhxj3r6pndirghkema3cc6pny	42	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	42	7	chemical	chemical	NNP
work_clhxj3r6pndirghkema3cc6pny	42	8	recog-	recog-	NNP
work_clhxj3r6pndirghkema3cc6pny	42	9	nition	nition	NN
work_clhxj3r6pndirghkema3cc6pny	42	10	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	42	11	physiologic	physiologic	JJ
work_clhxj3r6pndirghkema3cc6pny	42	12	action	action	NN
work_clhxj3r6pndirghkema3cc6pny	42	13	.	.	.
work_clhxj3r6pndirghkema3cc6pny	43	1	Recognition	recognition	NN
work_clhxj3r6pndirghkema3cc6pny	43	2	is	be	VBZ
work_clhxj3r6pndirghkema3cc6pny	43	3	highly	highly	RB
work_clhxj3r6pndirghkema3cc6pny	43	4	specific	specific	JJ
work_clhxj3r6pndirghkema3cc6pny	43	5	,	,	,
work_clhxj3r6pndirghkema3cc6pny	43	6	such	such	JJ
work_clhxj3r6pndirghkema3cc6pny	43	7	that	that	IN
work_clhxj3r6pndirghkema3cc6pny	43	8	only	only	RB
work_clhxj3r6pndirghkema3cc6pny	43	9	L	l	NN
work_clhxj3r6pndirghkema3cc6pny	43	10	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	43	11	isomers	isomer	NNS
work_clhxj3r6pndirghkema3cc6pny	43	12	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	43	13	certain	certain	JJ
work_clhxj3r6pndirghkema3cc6pny	43	14	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	43	15	exert	exert	VBP
work_clhxj3r6pndirghkema3cc6pny	43	16	analgesic	analgesic	JJ
work_clhxj3r6pndirghkema3cc6pny	43	17	activity	activity	NN
work_clhxj3r6pndirghkema3cc6pny	43	18	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	43	19	11	11	CD
work_clhxj3r6pndirghkema3cc6pny	43	20	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	43	21	.	.	.
work_clhxj3r6pndirghkema3cc6pny	44	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	44	2	binding	bind	VBG
work_clhxj3r6pndirghkema3cc6pny	44	3	affinity	affinity	NN
work_clhxj3r6pndirghkema3cc6pny	44	4	varies	vary	VBZ
work_clhxj3r6pndirghkema3cc6pny	44	5	considerably	considerably	RB
work_clhxj3r6pndirghkema3cc6pny	44	6	among	among	IN
work_clhxj3r6pndirghkema3cc6pny	44	7	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	44	8	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	44	9	12	12	CD
work_clhxj3r6pndirghkema3cc6pny	44	10	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	44	11	.	.	.
work_clhxj3r6pndirghkema3cc6pny	45	1	Fentanyl	Fentanyl	NNP
work_clhxj3r6pndirghkema3cc6pny	45	2	,	,	,
work_clhxj3r6pndirghkema3cc6pny	45	3	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	45	4	example	example	NN
work_clhxj3r6pndirghkema3cc6pny	45	5	,	,	,
work_clhxj3r6pndirghkema3cc6pny	45	6	has	have	VBZ
work_clhxj3r6pndirghkema3cc6pny	45	7	higher	high	JJR
work_clhxj3r6pndirghkema3cc6pny	45	8	binding	binding	NN
work_clhxj3r6pndirghkema3cc6pny	45	9	affinity	affinity	NN
work_clhxj3r6pndirghkema3cc6pny	45	10	than	than	IN
work_clhxj3r6pndirghkema3cc6pny	45	11	morphine	morphine	NN
work_clhxj3r6pndirghkema3cc6pny	45	12	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	45	13	11	11	CD
work_clhxj3r6pndirghkema3cc6pny	45	14	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	45	15	.	.	.
work_clhxj3r6pndirghkema3cc6pny	46	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	46	2	binding	bind	VBG
work_clhxj3r6pndirghkema3cc6pny	46	3	affinities	affinity	NNS
work_clhxj3r6pndirghkema3cc6pny	46	4	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	46	5	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	46	6	appear	appear	VBP
work_clhxj3r6pndirghkema3cc6pny	46	7	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	46	8	correlate	correlate	VB
work_clhxj3r6pndirghkema3cc6pny	46	9	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	46	10	their	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	46	11	analgesic	analgesic	JJ
work_clhxj3r6pndirghkema3cc6pny	46	12	potencies	potency	NNS
work_clhxj3r6pndirghkema3cc6pny	46	13	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	46	14	13	13	CD
work_clhxj3r6pndirghkema3cc6pny	46	15	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	46	16	.	.	.
work_clhxj3r6pndirghkema3cc6pny	47	1	Physiologically	physiologically	RB
work_clhxj3r6pndirghkema3cc6pny	47	2	,	,	,
work_clhxj3r6pndirghkema3cc6pny	47	3	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	47	4	binding	bind	VBG
work_clhxj3r6pndirghkema3cc6pny	47	5	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	47	6	receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	47	7	,	,	,
work_clhxj3r6pndirghkema3cc6pny	47	8	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	47	9	initiate	initiate	VBP
work_clhxj3r6pndirghkema3cc6pny	47	10	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	47	11	series	series	NN
work_clhxj3r6pndirghkema3cc6pny	47	12	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	47	13	biochemi-	biochemi-	NN
work_clhxj3r6pndirghkema3cc6pny	47	14	cal	cal	NN
work_clhxj3r6pndirghkema3cc6pny	47	15	events	event	NNS
work_clhxj3r6pndirghkema3cc6pny	47	16	including	include	VBG
work_clhxj3r6pndirghkema3cc6pny	47	17	activation	activation	NN
work_clhxj3r6pndirghkema3cc6pny	47	18	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	47	19	G	g	NN
work_clhxj3r6pndirghkema3cc6pny	47	20	proteins	protein	NNS
work_clhxj3r6pndirghkema3cc6pny	47	21	,	,	,
work_clhxj3r6pndirghkema3cc6pny	47	22	inhibition	inhibition	NN
work_clhxj3r6pndirghkema3cc6pny	47	23	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	47	24	adenylate	adenylate	NN
work_clhxj3r6pndirghkema3cc6pny	47	25	cyclase	cyclase	NN
work_clhxj3r6pndirghkema3cc6pny	47	26	,	,	,
work_clhxj3r6pndirghkema3cc6pny	47	27	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	47	28	extrusion	extrusion	NN
work_clhxj3r6pndirghkema3cc6pny	47	29	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	47	30	potassium	potassium	NN
work_clhxj3r6pndirghkema3cc6pny	47	31	ions	ion	NNS
work_clhxj3r6pndirghkema3cc6pny	47	32	,	,	,
work_clhxj3r6pndirghkema3cc6pny	47	33	resulting	result	VBG
work_clhxj3r6pndirghkema3cc6pny	47	34	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	47	35	hyperpolarization	hyperpolarization	NN
work_clhxj3r6pndirghkema3cc6pny	47	36	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	47	37	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	47	38	membranes	membrane	NNS
work_clhxj3r6pndirghkema3cc6pny	47	39	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	47	40	14	14	CD
work_clhxj3r6pndirghkema3cc6pny	47	41	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	47	42	16	16	CD
work_clhxj3r6pndirghkema3cc6pny	47	43	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	47	44	;	;	:
work_clhxj3r6pndirghkema3cc6pny	47	45	this	this	DT
work_clhxj3r6pndirghkema3cc6pny	47	46	delays	delay	NNS
work_clhxj3r6pndirghkema3cc6pny	47	47	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	47	48	prevents	prevent	VBZ
work_clhxj3r6pndirghkema3cc6pny	47	49	transmission	transmission	NN
work_clhxj3r6pndirghkema3cc6pny	47	50	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	47	51	painful	painful	JJ
work_clhxj3r6pndirghkema3cc6pny	47	52	stimuli	stimulus	NNS
work_clhxj3r6pndirghkema3cc6pny	47	53	.	.	.
work_clhxj3r6pndirghkema3cc6pny	48	1	Thus	thus	RB
work_clhxj3r6pndirghkema3cc6pny	48	2	,	,	,
work_clhxj3r6pndirghkema3cc6pny	48	3	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	48	4	riddle	riddle	NN
work_clhxj3r6pndirghkema3cc6pny	48	5	why	why	WRB
work_clhxj3r6pndirghkema3cc6pny	48	6	some	some	DT
work_clhxj3r6pndirghkema3cc6pny	48	7	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	48	8	respond	respond	VBP
work_clhxj3r6pndirghkema3cc6pny	48	9	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	48	10	one	one	CD
work_clhxj3r6pndirghkema3cc6pny	48	11	opioid	opioid	NN
work_clhxj3r6pndirghkema3cc6pny	48	12	but	but	CC
work_clhxj3r6pndirghkema3cc6pny	48	13	not	not	RB
work_clhxj3r6pndirghkema3cc6pny	48	14	another	another	DT
work_clhxj3r6pndirghkema3cc6pny	48	15	had	have	VBD
work_clhxj3r6pndirghkema3cc6pny	48	16	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	48	17	pathophysiologic	pathophysiologic	JJ
work_clhxj3r6pndirghkema3cc6pny	48	18	explanation	explanation	NN
work_clhxj3r6pndirghkema3cc6pny	48	19	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	48	20	17	17	CD
work_clhxj3r6pndirghkema3cc6pny	48	21	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	48	22	.	.	.
work_clhxj3r6pndirghkema3cc6pny	49	1	Parallel	parallel	NN
work_clhxj3r6pndirghkema3cc6pny	49	2	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	49	3	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	49	4	progress	progress	NN
work_clhxj3r6pndirghkema3cc6pny	49	5	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	49	6	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	49	7	pharmacodynamics	pharmacodynamic	NNS
work_clhxj3r6pndirghkema3cc6pny	49	8	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	49	9	opi-	opi-	NNS
work_clhxj3r6pndirghkema3cc6pny	49	10	oids	oid	NNS
work_clhxj3r6pndirghkema3cc6pny	49	11	mentioned	mention	VBN
work_clhxj3r6pndirghkema3cc6pny	49	12	above	above	RB
work_clhxj3r6pndirghkema3cc6pny	49	13	,	,	,
work_clhxj3r6pndirghkema3cc6pny	49	14	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	49	15	concomitant	concomitant	JJ
work_clhxj3r6pndirghkema3cc6pny	49	16	advance	advance	NN
work_clhxj3r6pndirghkema3cc6pny	49	17	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	49	18	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	49	19	phar-	phar-	NNP
work_clhxj3r6pndirghkema3cc6pny	49	20	macokinetics	macokinetics	NNPS
work_clhxj3r6pndirghkema3cc6pny	49	21	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	49	22	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	49	23	was	be	VBD
work_clhxj3r6pndirghkema3cc6pny	49	24	bubbling	bubble	VBG
work_clhxj3r6pndirghkema3cc6pny	49	25	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	49	26	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	49	27	surface	surface	NN
work_clhxj3r6pndirghkema3cc6pny	49	28	.	.	.
work_clhxj3r6pndirghkema3cc6pny	50	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	50	2	metabolism	metabolism	NN
work_clhxj3r6pndirghkema3cc6pny	50	3	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	50	4	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	50	5	includes	include	VBZ
work_clhxj3r6pndirghkema3cc6pny	50	6	two	two	CD
work_clhxj3r6pndirghkema3cc6pny	50	7	major	major	JJ
work_clhxj3r6pndirghkema3cc6pny	50	8	phases	phase	NNS
work_clhxj3r6pndirghkema3cc6pny	50	9	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	50	10	18	18	CD
work_clhxj3r6pndirghkema3cc6pny	50	11	,	,	,
work_clhxj3r6pndirghkema3cc6pny	50	12	19	19	CD
work_clhxj3r6pndirghkema3cc6pny	50	13	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	50	14	.	.	.
work_clhxj3r6pndirghkema3cc6pny	51	1	Figure	figure	NN
work_clhxj3r6pndirghkema3cc6pny	51	2	2	2	CD
work_clhxj3r6pndirghkema3cc6pny	51	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	52	1	Helical	helical	JJ
work_clhxj3r6pndirghkema3cc6pny	52	2	structure	structure	NN
work_clhxj3r6pndirghkema3cc6pny	52	3	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	52	4	opioid	opioid	JJ
work_clhxj3r6pndirghkema3cc6pny	52	5	receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	52	6	.	.	.
work_clhxj3r6pndirghkema3cc6pny	53	1	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	53	2	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	53	3	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	53	4	Morphine	Morphine	NNP
work_clhxj3r6pndirghkema3cc6pny	53	5	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	53	6	like	like	JJ
work_clhxj3r6pndirghkema3cc6pny	53	7	molecule	molecule	NN
work_clhxj3r6pndirghkema3cc6pny	53	8	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	53	9	yellow	yellow	NN
work_clhxj3r6pndirghkema3cc6pny	53	10	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	53	11	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	53	12	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	53	13	deep	deep	JJ
work_clhxj3r6pndirghkema3cc6pny	53	14	pocket	pocket	NN
work_clhxj3r6pndirghkema3cc6pny	53	15	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	53	16	blue	blue	NNP
work_clhxj3r6pndirghkema3cc6pny	53	17	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	53	18	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	53	19	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	53	20	μ	μ	NN
work_clhxj3r6pndirghkema3cc6pny	53	21	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	53	22	opioid	opioid	NN
work_clhxj3r6pndirghkema3cc6pny	53	23	recep-	recep-	NN
work_clhxj3r6pndirghkema3cc6pny	53	24	tor	tor	NN
work_clhxj3r6pndirghkema3cc6pny	53	25	.	.	.
work_clhxj3r6pndirghkema3cc6pny	54	1	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	54	2	b	b	NN
work_clhxj3r6pndirghkema3cc6pny	54	3	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	54	4	μ	μ	LS
work_clhxj3r6pndirghkema3cc6pny	54	5	-	-	:
work_clhxj3r6pndirghkema3cc6pny	54	6	Opioid	opioid	JJ
work_clhxj3r6pndirghkema3cc6pny	54	7	receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	54	8	from	from	IN
work_clhxj3r6pndirghkema3cc6pny	54	9	an	an	DT
work_clhxj3r6pndirghkema3cc6pny	54	10	intimate	intimate	JJ
work_clhxj3r6pndirghkema3cc6pny	54	11	pair	pair	NN
work_clhxj3r6pndirghkema3cc6pny	54	12	when	when	WRB
work_clhxj3r6pndirghkema3cc6pny	54	13	crystallized	crystallize	VBN
work_clhxj3r6pndirghkema3cc6pny	54	14	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	54	15	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	54	16	ligand	ligand	NN
work_clhxj3r6pndirghkema3cc6pny	54	17	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	54	18	yellow	yellow	NN
work_clhxj3r6pndirghkema3cc6pny	54	19	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	54	20	such	such	JJ
work_clhxj3r6pndirghkema3cc6pny	54	21	as	as	IN
work_clhxj3r6pndirghkema3cc6pny	54	22	morphine	morphine	NN
work_clhxj3r6pndirghkema3cc6pny	54	23	.	.	.
work_clhxj3r6pndirghkema3cc6pny	55	1	Knowing	know	VBG
work_clhxj3r6pndirghkema3cc6pny	55	2	how	how	WRB
work_clhxj3r6pndirghkema3cc6pny	55	3	an	an	DT
work_clhxj3r6pndirghkema3cc6pny	55	4	opioid	opioid	NN
work_clhxj3r6pndirghkema3cc6pny	55	5	molecule	molecule	NN
work_clhxj3r6pndirghkema3cc6pny	55	6	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	55	7	yellow	yellow	JJ
work_clhxj3r6pndirghkema3cc6pny	55	8	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	55	9	sticks	stick	NNS
work_clhxj3r6pndirghkema3cc6pny	55	10	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	55	11	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	55	12	pocket	pocket	NN
work_clhxj3r6pndirghkema3cc6pny	55	13	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	55	14	its	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	55	15	receptor	receptor	NN
work_clhxj3r6pndirghkema3cc6pny	55	16	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	55	17	blue	blue	NNP
work_clhxj3r6pndirghkema3cc6pny	55	18	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	55	19	could	could	MD
work_clhxj3r6pndirghkema3cc6pny	55	20	help	help	VB
work_clhxj3r6pndirghkema3cc6pny	55	21	scientists	scientist	NNS
work_clhxj3r6pndirghkema3cc6pny	55	22	design	design	VB
work_clhxj3r6pndirghkema3cc6pny	55	23	better	well	JJR
work_clhxj3r6pndirghkema3cc6pny	55	24	analgesics	analgesic	NNS
work_clhxj3r6pndirghkema3cc6pny	55	25	that	that	WDT
work_clhxj3r6pndirghkema3cc6pny	55	26	are	be	VBP
work_clhxj3r6pndirghkema3cc6pny	55	27	more	more	RBR
work_clhxj3r6pndirghkema3cc6pny	55	28	effective	effective	JJ
work_clhxj3r6pndirghkema3cc6pny	55	29	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	55	30	less	less	RBR
work_clhxj3r6pndirghkema3cc6pny	55	31	addictive	addictive	JJ
work_clhxj3r6pndirghkema3cc6pny	55	32	.	.	.
work_clhxj3r6pndirghkema3cc6pny	56	1	Credit	credit	NN
work_clhxj3r6pndirghkema3cc6pny	56	2	:	:	:
work_clhxj3r6pndirghkema3cc6pny	56	3	Kobilka	Kobilka	NNP
work_clhxj3r6pndirghkema3cc6pny	56	4	Lab	Lab	NNP
work_clhxj3r6pndirghkema3cc6pny	56	5	,	,	,
work_clhxj3r6pndirghkema3cc6pny	56	6	Nature	Nature	NNP
work_clhxj3r6pndirghkema3cc6pny	56	7	.	.	.
work_clhxj3r6pndirghkema3cc6pny	57	1	2012;485:321	2012;485:321	LS
work_clhxj3r6pndirghkema3cc6pny	57	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	57	3	6	6	CD
work_clhxj3r6pndirghkema3cc6pny	57	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	58	1	Used	use	VBN
work_clhxj3r6pndirghkema3cc6pny	58	2	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	58	3	permission	permission	NN
work_clhxj3r6pndirghkema3cc6pny	58	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	59	1	Figure	figure	NN
work_clhxj3r6pndirghkema3cc6pny	59	2	1	1	CD
work_clhxj3r6pndirghkema3cc6pny	59	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	60	1	Life	life	NN
work_clhxj3r6pndirghkema3cc6pny	60	2	expectancy	expectancy	NN
work_clhxj3r6pndirghkema3cc6pny	60	3	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	60	4	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	60	5	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	60	6	sickle	sickle	NN
work_clhxj3r6pndirghkema3cc6pny	60	7	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	60	8	disease	disease	NN
work_clhxj3r6pndirghkema3cc6pny	60	9	from	from	IN
work_clhxj3r6pndirghkema3cc6pny	60	10	1900	1900	CD
work_clhxj3r6pndirghkema3cc6pny	60	11	through	through	IN
work_clhxj3r6pndirghkema3cc6pny	60	12	2010	2010	CD
work_clhxj3r6pndirghkema3cc6pny	60	13	.	.	.
work_clhxj3r6pndirghkema3cc6pny	61	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	61	2	arrow	arrow	NN
work_clhxj3r6pndirghkema3cc6pny	61	3	indicates	indicate	VBZ
work_clhxj3r6pndirghkema3cc6pny	61	4	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	61	5	infliction	infliction	NN
work_clhxj3r6pndirghkema3cc6pny	61	6	point	point	NN
work_clhxj3r6pndirghkema3cc6pny	61	7	where	where	WRB
work_clhxj3r6pndirghkema3cc6pny	61	8	life	life	NN
work_clhxj3r6pndirghkema3cc6pny	61	9	expectancy	expectancy	NN
work_clhxj3r6pndirghkema3cc6pny	61	10	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	61	11	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	61	12	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	61	13	sickle	sickle	NN
work_clhxj3r6pndirghkema3cc6pny	61	14	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	61	15	disease	disease	NN
work_clhxj3r6pndirghkema3cc6pny	61	16	began	begin	VBD
work_clhxj3r6pndirghkema3cc6pny	61	17	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	61	18	increase	increase	VB
work_clhxj3r6pndirghkema3cc6pny	61	19	.	.	.
work_clhxj3r6pndirghkema3cc6pny	62	1	Adapted	adapt	VBN
work_clhxj3r6pndirghkema3cc6pny	62	2	from	from	IN
work_clhxj3r6pndirghkema3cc6pny	62	3	National	National	NNP
work_clhxj3r6pndirghkema3cc6pny	62	4	Heart	Heart	NNP
work_clhxj3r6pndirghkema3cc6pny	62	5	,	,	,
work_clhxj3r6pndirghkema3cc6pny	62	6	Lung	Lung	NNP
work_clhxj3r6pndirghkema3cc6pny	62	7	,	,	,
work_clhxj3r6pndirghkema3cc6pny	62	8	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	62	9	Blood	Blood	NNP
work_clhxj3r6pndirghkema3cc6pny	62	10	In-	In-	NNP
work_clhxj3r6pndirghkema3cc6pny	62	11	stitute	stitute	NN
work_clhxj3r6pndirghkema3cc6pny	62	12	.	.	.
work_clhxj3r6pndirghkema3cc6pny	63	1	Sickle	sickle	NN
work_clhxj3r6pndirghkema3cc6pny	63	2	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	63	3	research	research	NN
work_clhxj3r6pndirghkema3cc6pny	63	4	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	63	5	treatment	treatment	NN
work_clhxj3r6pndirghkema3cc6pny	63	6	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	63	7	cure	cure	NN
work_clhxj3r6pndirghkema3cc6pny	63	8	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	63	9	NIH	NIH	NNP
work_clhxj3r6pndirghkema3cc6pny	63	10	Publication	Publication	NNP
work_clhxj3r6pndirghkema3cc6pny	63	11	No	no	UH
work_clhxj3r6pndirghkema3cc6pny	63	12	.	.	.
work_clhxj3r6pndirghkema3cc6pny	64	1	02	02	CD
work_clhxj3r6pndirghkema3cc6pny	64	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	64	3	5214	5214	CD
work_clhxj3r6pndirghkema3cc6pny	64	4	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	64	5	.	.	.
work_clhxj3r6pndirghkema3cc6pny	65	1	Bethesda	Bethesda	NNP
work_clhxj3r6pndirghkema3cc6pny	65	2	,	,	,
work_clhxj3r6pndirghkema3cc6pny	65	3	MD	MD	NNP
work_clhxj3r6pndirghkema3cc6pny	65	4	:	:	:
work_clhxj3r6pndirghkema3cc6pny	65	5	US	US	NNP
work_clhxj3r6pndirghkema3cc6pny	65	6	Department	Department	NNP
work_clhxj3r6pndirghkema3cc6pny	65	7	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	65	8	Health	Health	NNP
work_clhxj3r6pndirghkema3cc6pny	65	9	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	65	10	Human	Human	NNP
work_clhxj3r6pndirghkema3cc6pny	65	11	Services	Services	NNPS
work_clhxj3r6pndirghkema3cc6pny	65	12	.	.	.
work_clhxj3r6pndirghkema3cc6pny	66	1	Articles	article	NNS
work_clhxj3r6pndirghkema3cc6pny	66	2	©	©	NNP
work_clhxj3r6pndirghkema3cc6pny	66	3	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	66	4	authors	author	NNS
work_clhxj3r6pndirghkema3cc6pny	66	5	|	|	NNP
work_clhxj3r6pndirghkema3cc6pny	66	6	Journal	Journal	NNP
work_clhxj3r6pndirghkema3cc6pny	66	7	compilation	compilation	NN
work_clhxj3r6pndirghkema3cc6pny	66	8	©	©	NNP
work_clhxj3r6pndirghkema3cc6pny	66	9	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	66	10	Clin	Clin	NNP
work_clhxj3r6pndirghkema3cc6pny	66	11	Med	Med	NNP
work_clhxj3r6pndirghkema3cc6pny	66	12	Res	Res	NNP
work_clhxj3r6pndirghkema3cc6pny	66	13	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	66	14	Elmer	Elmer	NNP
work_clhxj3r6pndirghkema3cc6pny	66	15	Press	Press	NNP
work_clhxj3r6pndirghkema3cc6pny	66	16	Inc	Inc	NNP
work_clhxj3r6pndirghkema3cc6pny	66	17	™	™	CD
work_clhxj3r6pndirghkema3cc6pny	66	18	|	|	NNP
work_clhxj3r6pndirghkema3cc6pny	66	19	www.jocmr.org	www.jocmr.org	IN
work_clhxj3r6pndirghkema3cc6pny	66	20	359	359	CD
work_clhxj3r6pndirghkema3cc6pny	66	21	Ballas	balla	NNS
work_clhxj3r6pndirghkema3cc6pny	66	22	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	66	23	Clin	Clin	NNP
work_clhxj3r6pndirghkema3cc6pny	66	24	Med	Med	NNP
work_clhxj3r6pndirghkema3cc6pny	66	25	Res	Res	NNP
work_clhxj3r6pndirghkema3cc6pny	66	26	.	.	.
work_clhxj3r6pndirghkema3cc6pny	67	1	2016;8(5):357	2016;8(5):357	CD
work_clhxj3r6pndirghkema3cc6pny	67	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	67	3	360	360	CD
work_clhxj3r6pndirghkema3cc6pny	67	4	Phase	Phase	NNP
work_clhxj3r6pndirghkema3cc6pny	67	5	I	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	67	6	involves	involve	VBZ
work_clhxj3r6pndirghkema3cc6pny	67	7	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	67	8	CYP	CYP	NNP
work_clhxj3r6pndirghkema3cc6pny	67	9	enzymes	enzyme	NNS
work_clhxj3r6pndirghkema3cc6pny	67	10	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	67	11	phase	phase	NN
work_clhxj3r6pndirghkema3cc6pny	67	12	II	ii	CD
work_clhxj3r6pndirghkema3cc6pny	67	13	metabolism	metabolism	NN
work_clhxj3r6pndirghkema3cc6pny	67	14	conjugates	conjugate	VBZ
work_clhxj3r6pndirghkema3cc6pny	67	15	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	67	16	drug	drug	NN
work_clhxj3r6pndirghkema3cc6pny	67	17	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	67	18	hydrophilic	hydrophilic	JJ
work_clhxj3r6pndirghkema3cc6pny	67	19	substances	substance	NNS
work_clhxj3r6pndirghkema3cc6pny	67	20	,	,	,
work_clhxj3r6pndirghkema3cc6pny	67	21	such	such	JJ
work_clhxj3r6pndirghkema3cc6pny	67	22	as	as	IN
work_clhxj3r6pndirghkema3cc6pny	67	23	glucu-	glucu-	NNP
work_clhxj3r6pndirghkema3cc6pny	67	24	ronic	ronic	NNP
work_clhxj3r6pndirghkema3cc6pny	67	25	acid	acid	NNP
work_clhxj3r6pndirghkema3cc6pny	67	26	,	,	,
work_clhxj3r6pndirghkema3cc6pny	67	27	sulfate	sulfate	NN
work_clhxj3r6pndirghkema3cc6pny	67	28	,	,	,
work_clhxj3r6pndirghkema3cc6pny	67	29	glycine	glycine	NN
work_clhxj3r6pndirghkema3cc6pny	67	30	,	,	,
work_clhxj3r6pndirghkema3cc6pny	67	31	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	67	32	glutathione	glutathione	NN
work_clhxj3r6pndirghkema3cc6pny	67	33	.	.	.
work_clhxj3r6pndirghkema3cc6pny	68	1	Glucuronidation	glucuronidation	NN
work_clhxj3r6pndirghkema3cc6pny	68	2	is	be	VBZ
work_clhxj3r6pndirghkema3cc6pny	68	3	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	68	4	most	most	RBS
work_clhxj3r6pndirghkema3cc6pny	68	5	important	important	JJ
work_clhxj3r6pndirghkema3cc6pny	68	6	phase	phase	NN
work_clhxj3r6pndirghkema3cc6pny	68	7	II	ii	CD
work_clhxj3r6pndirghkema3cc6pny	68	8	reaction	reaction	NN
work_clhxj3r6pndirghkema3cc6pny	68	9	.	.	.
work_clhxj3r6pndirghkema3cc6pny	69	1	It	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	69	2	is	be	VBZ
work_clhxj3r6pndirghkema3cc6pny	69	3	catalyzed	catalyze	VBN
work_clhxj3r6pndirghkema3cc6pny	69	4	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	69	5	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	69	6	enzyme	enzyme	NNS
work_clhxj3r6pndirghkema3cc6pny	69	7	uridine	uridine	NN
work_clhxj3r6pndirghkema3cc6pny	69	8	diphosphate	diphosphate	JJ
work_clhxj3r6pndirghkema3cc6pny	69	9	glucuronyltransferase	glucuronyltransferase	NN
work_clhxj3r6pndirghkema3cc6pny	69	10	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	69	11	UGT	UGT	NNP
work_clhxj3r6pndirghkema3cc6pny	69	12	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	69	13	.	.	.
work_clhxj3r6pndirghkema3cc6pny	70	1	Morphine	Morphine	NNP
work_clhxj3r6pndirghkema3cc6pny	70	2	,	,	,
work_clhxj3r6pndirghkema3cc6pny	70	3	hydromorphone	hydromorphone	NN
work_clhxj3r6pndirghkema3cc6pny	70	4	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	70	5	oxymorphone	oxymorphone	NN
work_clhxj3r6pndirghkema3cc6pny	70	6	are	be	VBP
work_clhxj3r6pndirghkema3cc6pny	70	7	metabo-	metabo-	RB
work_clhxj3r6pndirghkema3cc6pny	70	8	lized	lize	VBN
work_clhxj3r6pndirghkema3cc6pny	70	9	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	70	10	glucuronidation	glucuronidation	NN
work_clhxj3r6pndirghkema3cc6pny	70	11	,	,	,
work_clhxj3r6pndirghkema3cc6pny	70	12	whereas	whereas	IN
work_clhxj3r6pndirghkema3cc6pny	70	13	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	70	14	majority	majority	NN
work_clhxj3r6pndirghkema3cc6pny	70	15	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	70	16	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	70	17	other	other	JJ
work_clhxj3r6pndirghkema3cc6pny	70	18	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	70	19	are	be	VBP
work_clhxj3r6pndirghkema3cc6pny	70	20	metabolized	metabolize	VBN
work_clhxj3r6pndirghkema3cc6pny	70	21	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	70	22	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	70	23	cytochrome	cytochrome	JJ
work_clhxj3r6pndirghkema3cc6pny	70	24	P450	p450	NN
work_clhxj3r6pndirghkema3cc6pny	70	25	isoenzyme	isoenzyme	VBZ
work_clhxj3r6pndirghkema3cc6pny	70	26	system	system	NN
work_clhxj3r6pndirghkema3cc6pny	70	27	.	.	.
work_clhxj3r6pndirghkema3cc6pny	71	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	71	2	net	net	JJ
work_clhxj3r6pndirghkema3cc6pny	71	3	effect	effect	NN
work_clhxj3r6pndirghkema3cc6pny	71	4	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	71	5	an	an	DT
work_clhxj3r6pndirghkema3cc6pny	71	6	opioid	opioid	NN
work_clhxj3r6pndirghkema3cc6pny	71	7	depends	depend	VBZ
work_clhxj3r6pndirghkema3cc6pny	71	8	on	on	IN
work_clhxj3r6pndirghkema3cc6pny	71	9	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	71	10	availability	availability	NN
work_clhxj3r6pndirghkema3cc6pny	71	11	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	71	12	enzyme(s	enzyme(s	NNP
work_clhxj3r6pndirghkema3cc6pny	71	13	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	71	14	to	to	TO
work_clhxj3r6pndirghkema3cc6pny	71	15	convert	convert	VB
work_clhxj3r6pndirghkema3cc6pny	71	16	it	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	71	17	into	into	IN
work_clhxj3r6pndirghkema3cc6pny	71	18	metabolites	metabolite	NNS
work_clhxj3r6pndirghkema3cc6pny	71	19	that	that	WDT
work_clhxj3r6pndirghkema3cc6pny	71	20	could	could	MD
work_clhxj3r6pndirghkema3cc6pny	71	21	be	be	VB
work_clhxj3r6pndirghkema3cc6pny	71	22	active	active	JJ
work_clhxj3r6pndirghkema3cc6pny	71	23	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	71	24	inactive	inactive	JJ
work_clhxj3r6pndirghkema3cc6pny	71	25	.	.	.
work_clhxj3r6pndirghkema3cc6pny	72	1	Briefly	briefly	RB
work_clhxj3r6pndirghkema3cc6pny	72	2	,	,	,
work_clhxj3r6pndirghkema3cc6pny	72	3	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	72	4	CYP2D6	cyp2d6	JJ
work_clhxj3r6pndirghkema3cc6pny	72	5	genotypes	genotype	NNS
work_clhxj3r6pndirghkema3cc6pny	72	6	are	be	VBP
work_clhxj3r6pndirghkema3cc6pny	72	7	categorized	categorize	VBN
work_clhxj3r6pndirghkema3cc6pny	72	8	into	into	IN
work_clhxj3r6pndirghkema3cc6pny	72	9	phenotypes	phenotype	NNS
work_clhxj3r6pndirghkema3cc6pny	72	10	based	base	VBN
work_clhxj3r6pndirghkema3cc6pny	72	11	on	on	IN
work_clhxj3r6pndirghkema3cc6pny	72	12	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	72	13	activity	activity	NN
work_clhxj3r6pndirghkema3cc6pny	72	14	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	72	15	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	72	16	variant	variant	JJ
work_clhxj3r6pndirghkema3cc6pny	72	17	enzymes	enzyme	NNS
work_clhxj3r6pndirghkema3cc6pny	72	18	.	.	.
work_clhxj3r6pndirghkema3cc6pny	73	1	Ultrarapid	ultrarapid	JJ
work_clhxj3r6pndirghkema3cc6pny	73	2	metabolizers	metabolizer	NNS
work_clhxj3r6pndirghkema3cc6pny	73	3	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	73	4	UMs	UMs	NNP
work_clhxj3r6pndirghkema3cc6pny	73	5	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	73	6	have	have	VBP
work_clhxj3r6pndirghkema3cc6pny	73	7	greater	great	JJR
work_clhxj3r6pndirghkema3cc6pny	73	8	than	than	IN
work_clhxj3r6pndirghkema3cc6pny	73	9	normal	normal	JJ
work_clhxj3r6pndirghkema3cc6pny	73	10	activ-	activ-	NN
work_clhxj3r6pndirghkema3cc6pny	73	11	ity	ity	NN
work_clhxj3r6pndirghkema3cc6pny	73	12	due	due	IN
work_clhxj3r6pndirghkema3cc6pny	73	13	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	73	14	duplication	duplication	NN
work_clhxj3r6pndirghkema3cc6pny	73	15	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	73	16	triplication	triplication	NN
work_clhxj3r6pndirghkema3cc6pny	73	17	,	,	,
work_clhxj3r6pndirghkema3cc6pny	73	18	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	73	19	active	active	JJ
work_clhxj3r6pndirghkema3cc6pny	73	20	alleles	allele	NNS
work_clhxj3r6pndirghkema3cc6pny	73	21	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	73	22	20	20	CD
work_clhxj3r6pndirghkema3cc6pny	73	23	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	73	24	23	23	CD
work_clhxj3r6pndirghkema3cc6pny	73	25	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	73	26	,	,	,
work_clhxj3r6pndirghkema3cc6pny	73	27	extensive	extensive	JJ
work_clhxj3r6pndirghkema3cc6pny	73	28	metabolizers	metabolizer	NNS
work_clhxj3r6pndirghkema3cc6pny	73	29	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	73	30	EMs	em	NNS
work_clhxj3r6pndirghkema3cc6pny	73	31	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	73	32	have	have	VBP
work_clhxj3r6pndirghkema3cc6pny	73	33	normal	normal	JJ
work_clhxj3r6pndirghkema3cc6pny	73	34	enzyme	enzyme	NNS
work_clhxj3r6pndirghkema3cc6pny	73	35	activity	activity	NN
work_clhxj3r6pndirghkema3cc6pny	73	36	,	,	,
work_clhxj3r6pndirghkema3cc6pny	73	37	intermediate	intermediate	JJ
work_clhxj3r6pndirghkema3cc6pny	73	38	metabolizers	metabolizer	NNS
work_clhxj3r6pndirghkema3cc6pny	73	39	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	73	40	IMs	im	NNS
work_clhxj3r6pndirghkema3cc6pny	73	41	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	73	42	have	have	VBP
work_clhxj3r6pndirghkema3cc6pny	73	43	decreased	decrease	VBN
work_clhxj3r6pndirghkema3cc6pny	73	44	enzyme	enzyme	NNS
work_clhxj3r6pndirghkema3cc6pny	73	45	activ-	activ-	JJ
work_clhxj3r6pndirghkema3cc6pny	73	46	ity	ity	NN
work_clhxj3r6pndirghkema3cc6pny	73	47	,	,	,
work_clhxj3r6pndirghkema3cc6pny	73	48	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	73	49	poor	poor	JJ
work_clhxj3r6pndirghkema3cc6pny	73	50	metabolizers	metabolizer	NNS
work_clhxj3r6pndirghkema3cc6pny	73	51	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	73	52	PMs	PMs	NNP
work_clhxj3r6pndirghkema3cc6pny	73	53	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	73	54	have	have	VBP
work_clhxj3r6pndirghkema3cc6pny	73	55	absent	absent	JJ
work_clhxj3r6pndirghkema3cc6pny	73	56	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	73	57	little	little	JJ
work_clhxj3r6pndirghkema3cc6pny	73	58	enzyme	enzyme	NNS
work_clhxj3r6pndirghkema3cc6pny	73	59	activity	activity	NN
work_clhxj3r6pndirghkema3cc6pny	73	60	.	.	.
work_clhxj3r6pndirghkema3cc6pny	74	1	Thus	thus	RB
work_clhxj3r6pndirghkema3cc6pny	74	2	,	,	,
work_clhxj3r6pndirghkema3cc6pny	74	3	fentanyl	fentanyl	NN
work_clhxj3r6pndirghkema3cc6pny	74	4	,	,	,
work_clhxj3r6pndirghkema3cc6pny	74	5	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	74	6	example	example	NN
work_clhxj3r6pndirghkema3cc6pny	74	7	,	,	,
work_clhxj3r6pndirghkema3cc6pny	74	8	is	be	VBZ
work_clhxj3r6pndirghkema3cc6pny	74	9	normally	normally	RB
work_clhxj3r6pndirghkema3cc6pny	74	10	metabolized	metabolize	VBN
work_clhxj3r6pndirghkema3cc6pny	74	11	into	into	IN
work_clhxj3r6pndirghkema3cc6pny	74	12	inactive	inactive	JJ
work_clhxj3r6pndirghkema3cc6pny	74	13	metabolites	metabolite	NNS
work_clhxj3r6pndirghkema3cc6pny	74	14	.	.	.
work_clhxj3r6pndirghkema3cc6pny	75	1	Patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	75	2	who	who	WP
work_clhxj3r6pndirghkema3cc6pny	75	3	are	be	VBP
work_clhxj3r6pndirghkema3cc6pny	75	4	UMs	um	NNS
work_clhxj3r6pndirghkema3cc6pny	75	5	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	75	6	fentanyl	fentanyl	NN
work_clhxj3r6pndirghkema3cc6pny	75	7	would	would	MD
work_clhxj3r6pndirghkema3cc6pny	75	8	rapidly	rapidly	RB
work_clhxj3r6pndirghkema3cc6pny	75	9	convert	convert	VB
work_clhxj3r6pndirghkema3cc6pny	75	10	it	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	75	11	into	into	IN
work_clhxj3r6pndirghkema3cc6pny	75	12	inactive	inactive	JJ
work_clhxj3r6pndirghkema3cc6pny	75	13	metabolites	metabolite	NNS
work_clhxj3r6pndirghkema3cc6pny	75	14	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	75	15	mini-	mini-	NNP
work_clhxj3r6pndirghkema3cc6pny	75	16	mal	mal	NNP
work_clhxj3r6pndirghkema3cc6pny	75	17	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	75	18	absent	absent	JJ
work_clhxj3r6pndirghkema3cc6pny	75	19	analgesic	analgesic	JJ
work_clhxj3r6pndirghkema3cc6pny	75	20	effect	effect	NN
work_clhxj3r6pndirghkema3cc6pny	75	21	requiring	require	VBG
work_clhxj3r6pndirghkema3cc6pny	75	22	increasing	increase	VBG
work_clhxj3r6pndirghkema3cc6pny	75	23	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	75	24	dose	dose	NN
work_clhxj3r6pndirghkema3cc6pny	75	25	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	75	26	fentanyl	fentanyl	NN
work_clhxj3r6pndirghkema3cc6pny	75	27	.	.	.
work_clhxj3r6pndirghkema3cc6pny	76	1	On	on	IN
work_clhxj3r6pndirghkema3cc6pny	76	2	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	76	3	other	other	JJ
work_clhxj3r6pndirghkema3cc6pny	76	4	hand	hand	NN
work_clhxj3r6pndirghkema3cc6pny	76	5	,	,	,
work_clhxj3r6pndirghkema3cc6pny	76	6	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	76	7	who	who	WP
work_clhxj3r6pndirghkema3cc6pny	76	8	are	be	VBP
work_clhxj3r6pndirghkema3cc6pny	76	9	PMs	pm	NNS
work_clhxj3r6pndirghkema3cc6pny	76	10	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	76	11	fentanyl	fentanyl	NN
work_clhxj3r6pndirghkema3cc6pny	76	12	would	would	MD
work_clhxj3r6pndirghkema3cc6pny	76	13	experience	experience	VB
work_clhxj3r6pndirghkema3cc6pny	76	14	prompt	prompt	JJ
work_clhxj3r6pndirghkema3cc6pny	76	15	relief	relief	NN
work_clhxj3r6pndirghkema3cc6pny	76	16	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	76	17	relatively	relatively	RB
work_clhxj3r6pndirghkema3cc6pny	76	18	small	small	JJ
work_clhxj3r6pndirghkema3cc6pny	76	19	doses	dose	NNS
work_clhxj3r6pndirghkema3cc6pny	76	20	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	76	21	fentanyl	fentanyl	NN
work_clhxj3r6pndirghkema3cc6pny	76	22	but	but	CC
work_clhxj3r6pndirghkema3cc6pny	76	23	higher	high	JJR
work_clhxj3r6pndirghkema3cc6pny	76	24	doses	dose	NNS
work_clhxj3r6pndirghkema3cc6pny	76	25	could	could	MD
work_clhxj3r6pndirghkema3cc6pny	76	26	be	be	VB
work_clhxj3r6pndirghkema3cc6pny	76	27	toxic	toxic	JJ
work_clhxj3r6pndirghkema3cc6pny	76	28	due	due	IN
work_clhxj3r6pndirghkema3cc6pny	76	29	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	76	30	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	76	31	accu-	accu-	NN
work_clhxj3r6pndirghkema3cc6pny	76	32	mulation	mulation	NN
work_clhxj3r6pndirghkema3cc6pny	76	33	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	76	34	unmetabolized	unmetabolized	JJ
work_clhxj3r6pndirghkema3cc6pny	76	35	fentanyl	fentanyl	NN
work_clhxj3r6pndirghkema3cc6pny	76	36	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	76	37	24	24	CD
work_clhxj3r6pndirghkema3cc6pny	76	38	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	76	39	.	.	.
work_clhxj3r6pndirghkema3cc6pny	77	1	Phase	phase	NN
work_clhxj3r6pndirghkema3cc6pny	77	2	I	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	77	3	metabolism	metabolism	NN
work_clhxj3r6pndirghkema3cc6pny	77	4	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	77	5	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	77	6	involves	involve	VBZ
work_clhxj3r6pndirghkema3cc6pny	77	7	primarily	primarily	RB
work_clhxj3r6pndirghkema3cc6pny	77	8	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	77	9	CYP3A4	CYP3A4	NNP
work_clhxj3r6pndirghkema3cc6pny	77	10	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	77	11	CYP2D6	CYP2D6	NNP
work_clhxj3r6pndirghkema3cc6pny	77	12	en-	en-	NNP
work_clhxj3r6pndirghkema3cc6pny	77	13	zymes	zyme	NNS
work_clhxj3r6pndirghkema3cc6pny	77	14	.	.	.
work_clhxj3r6pndirghkema3cc6pny	78	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	78	2	CYP3A4	CYP3A4	NNP
work_clhxj3r6pndirghkema3cc6pny	78	3	enzyme	enzyme	NNS
work_clhxj3r6pndirghkema3cc6pny	78	4	metabolizes	metabolize	VBZ
work_clhxj3r6pndirghkema3cc6pny	78	5	more	more	JJR
work_clhxj3r6pndirghkema3cc6pny	78	6	than	than	IN
work_clhxj3r6pndirghkema3cc6pny	78	7	50	50	CD
work_clhxj3r6pndirghkema3cc6pny	78	8	%	%	NN
work_clhxj3r6pndirghkema3cc6pny	78	9	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	78	10	all	all	DT
work_clhxj3r6pndirghkema3cc6pny	78	11	drugs	drug	NNS
work_clhxj3r6pndirghkema3cc6pny	78	12	;	;	:
work_clhxj3r6pndirghkema3cc6pny	78	13	consequently	consequently	RB
work_clhxj3r6pndirghkema3cc6pny	78	14	,	,	,
work_clhxj3r6pndirghkema3cc6pny	78	15	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	78	16	metabolized	metabolize	VBN
work_clhxj3r6pndirghkema3cc6pny	78	17	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	78	18	this	this	DT
work_clhxj3r6pndirghkema3cc6pny	78	19	enzyme	enzyme	NNS
work_clhxj3r6pndirghkema3cc6pny	78	20	have	have	VBP
work_clhxj3r6pndirghkema3cc6pny	78	21	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	78	22	high	high	JJ
work_clhxj3r6pndirghkema3cc6pny	78	23	risk	risk	NN
work_clhxj3r6pndirghkema3cc6pny	78	24	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	78	25	drug	drug	NN
work_clhxj3r6pndirghkema3cc6pny	78	26	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	78	27	drug	drug	NN
work_clhxj3r6pndirghkema3cc6pny	78	28	interactions	interaction	NNS
work_clhxj3r6pndirghkema3cc6pny	78	29	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	78	30	19	19	CD
work_clhxj3r6pndirghkema3cc6pny	78	31	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	78	32	.	.	.
work_clhxj3r6pndirghkema3cc6pny	79	1	Conclusion	conclusion	NN
work_clhxj3r6pndirghkema3cc6pny	79	2	Together	together	RB
work_clhxj3r6pndirghkema3cc6pny	79	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	79	4	current	current	JJ
work_clhxj3r6pndirghkema3cc6pny	79	5	data	datum	NNS
work_clhxj3r6pndirghkema3cc6pny	79	6	on	on	IN
work_clhxj3r6pndirghkema3cc6pny	79	7	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	79	8	pharmacodynamics	pharmacodynamic	NNS
work_clhxj3r6pndirghkema3cc6pny	79	9	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	79	10	phar-	phar-	NNP
work_clhxj3r6pndirghkema3cc6pny	79	11	macokinetics	macokinetic	NNS
work_clhxj3r6pndirghkema3cc6pny	79	12	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	79	13	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	79	14	show	show	VBP
work_clhxj3r6pndirghkema3cc6pny	79	15	great	great	JJ
work_clhxj3r6pndirghkema3cc6pny	79	16	variability	variability	NN
work_clhxj3r6pndirghkema3cc6pny	79	17	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	79	18	genotypes	genotype	NNS
work_clhxj3r6pndirghkema3cc6pny	79	19	among	among	IN
work_clhxj3r6pndirghkema3cc6pny	79	20	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	79	21	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	79	22	extreme	extreme	JJ
work_clhxj3r6pndirghkema3cc6pny	79	23	variability	variability	NN
work_clhxj3r6pndirghkema3cc6pny	79	24	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	79	25	individual	individual	JJ
work_clhxj3r6pndirghkema3cc6pny	79	26	responses	response	NNS
work_clhxj3r6pndirghkema3cc6pny	79	27	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	79	28	opioids	opioid	NNS
work_clhxj3r6pndirghkema3cc6pny	79	29	.	.	.
work_clhxj3r6pndirghkema3cc6pny	80	1	Determining	determine	VBG
work_clhxj3r6pndirghkema3cc6pny	80	2	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	80	3	pharmacogenetics	pharmacogenetic	NNS
work_clhxj3r6pndirghkema3cc6pny	80	4	profile	profile	NN
work_clhxj3r6pndirghkema3cc6pny	80	5	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	80	6	each	each	DT
work_clhxj3r6pndirghkema3cc6pny	80	7	patient	patient	NN
work_clhxj3r6pndirghkema3cc6pny	80	8	facilitates	facilitate	VBZ
work_clhxj3r6pndirghkema3cc6pny	80	9	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	80	10	choice	choice	NN
work_clhxj3r6pndirghkema3cc6pny	80	11	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	80	12	drugs	drug	NNS
work_clhxj3r6pndirghkema3cc6pny	80	13	that	that	WDT
work_clhxj3r6pndirghkema3cc6pny	80	14	would	would	MD
work_clhxj3r6pndirghkema3cc6pny	80	15	be	be	VB
work_clhxj3r6pndirghkema3cc6pny	80	16	efficacious	efficacious	JJ
work_clhxj3r6pndirghkema3cc6pny	80	17	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	80	18	that	that	DT
work_clhxj3r6pndirghkema3cc6pny	80	19	patient	patient	NN
work_clhxj3r6pndirghkema3cc6pny	80	20	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	80	21	avoid	avoid	VB
work_clhxj3r6pndirghkema3cc6pny	80	22	those	those	DT
work_clhxj3r6pndirghkema3cc6pny	80	23	drugs	drug	NNS
work_clhxj3r6pndirghkema3cc6pny	80	24	associated	associate	VBN
work_clhxj3r6pndirghkema3cc6pny	80	25	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	80	26	harmful	harmful	JJ
work_clhxj3r6pndirghkema3cc6pny	80	27	drug	drug	NN
work_clhxj3r6pndirghkema3cc6pny	80	28	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	80	29	drug	drug	NN
work_clhxj3r6pndirghkema3cc6pny	80	30	interaction	interaction	NN
work_clhxj3r6pndirghkema3cc6pny	80	31	.	.	.
work_clhxj3r6pndirghkema3cc6pny	81	1	This	this	DT
work_clhxj3r6pndirghkema3cc6pny	81	2	approach	approach	NN
work_clhxj3r6pndirghkema3cc6pny	81	3	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	81	4	diagnostics	diagnostic	NNS
work_clhxj3r6pndirghkema3cc6pny	81	5	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	81	6	thera-	thera-	NNP
work_clhxj3r6pndirghkema3cc6pny	81	7	peutics	peutics	NNP
work_clhxj3r6pndirghkema3cc6pny	81	8	ushers	usher	NNS
work_clhxj3r6pndirghkema3cc6pny	81	9	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	81	10	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	81	11	dawn	dawn	NN
work_clhxj3r6pndirghkema3cc6pny	81	12	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	81	13	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	81	14	new	new	JJ
work_clhxj3r6pndirghkema3cc6pny	81	15	field	field	NN
work_clhxj3r6pndirghkema3cc6pny	81	16	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	81	17	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	81	18	management	management	NN
work_clhxj3r6pndirghkema3cc6pny	81	19	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	81	20	individual	individual	JJ
work_clhxj3r6pndirghkema3cc6pny	81	21	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	81	22	based	base	VBN
work_clhxj3r6pndirghkema3cc6pny	81	23	on	on	IN
work_clhxj3r6pndirghkema3cc6pny	81	24	their	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	81	25	unique	unique	JJ
work_clhxj3r6pndirghkema3cc6pny	81	26	pharmacogenet-	pharmacogenet-	NN
work_clhxj3r6pndirghkema3cc6pny	81	27	ics	ics	NN
work_clhxj3r6pndirghkema3cc6pny	81	28	,	,	,
work_clhxj3r6pndirghkema3cc6pny	81	29	phenotypic	phenotypic	NN
work_clhxj3r6pndirghkema3cc6pny	81	30	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	81	31	biomarker	biomarker	NN
work_clhxj3r6pndirghkema3cc6pny	81	32	characteristics	characteristic	NNS
work_clhxj3r6pndirghkema3cc6pny	81	33	.	.	.
work_clhxj3r6pndirghkema3cc6pny	82	1	This	this	DT
work_clhxj3r6pndirghkema3cc6pny	82	2	future	future	NN
work_clhxj3r6pndirghkema3cc6pny	82	3	ap-	ap-	NN
work_clhxj3r6pndirghkema3cc6pny	82	4	proach	proach	NN
work_clhxj3r6pndirghkema3cc6pny	82	5	is	be	VBZ
work_clhxj3r6pndirghkema3cc6pny	82	6	referred	refer	VBN
work_clhxj3r6pndirghkema3cc6pny	82	7	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	82	8	as	as	RB
work_clhxj3r6pndirghkema3cc6pny	82	9	personalized	personalized	JJ
work_clhxj3r6pndirghkema3cc6pny	82	10	medicine	medicine	NN
work_clhxj3r6pndirghkema3cc6pny	82	11	or	or	CC
work_clhxj3r6pndirghkema3cc6pny	82	12	,	,	,
work_clhxj3r6pndirghkema3cc6pny	82	13	more	more	RBR
work_clhxj3r6pndirghkema3cc6pny	82	14	recent-	recent-	XX
work_clhxj3r6pndirghkema3cc6pny	82	15	ly	ly	XX
work_clhxj3r6pndirghkema3cc6pny	82	16	,	,	,
work_clhxj3r6pndirghkema3cc6pny	82	17	precision	precision	NN
work_clhxj3r6pndirghkema3cc6pny	82	18	medicine	medicine	NN
work_clhxj3r6pndirghkema3cc6pny	82	19	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	82	20	25	25	CD
work_clhxj3r6pndirghkema3cc6pny	82	21	]	]	-RRB-
work_clhxj3r6pndirghkema3cc6pny	82	22	.	.	.
work_clhxj3r6pndirghkema3cc6pny	83	1	It	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	83	2	has	have	VBZ
work_clhxj3r6pndirghkema3cc6pny	83	3	already	already	RB
work_clhxj3r6pndirghkema3cc6pny	83	4	been	be	VBN
work_clhxj3r6pndirghkema3cc6pny	83	5	implemented	implement	VBN
work_clhxj3r6pndirghkema3cc6pny	83	6	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	83	7	certain	certain	JJ
work_clhxj3r6pndirghkema3cc6pny	83	8	cancer	cancer	NN
work_clhxj3r6pndirghkema3cc6pny	83	9	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	83	10	receiving	receive	VBG
work_clhxj3r6pndirghkema3cc6pny	83	11	chemotherapy	chemotherapy	NN
work_clhxj3r6pndirghkema3cc6pny	83	12	.	.	.
work_clhxj3r6pndirghkema3cc6pny	84	1	We	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	84	2	hope	hope	VBP
work_clhxj3r6pndirghkema3cc6pny	84	3	that	that	IN
work_clhxj3r6pndirghkema3cc6pny	84	4	this	this	DT
work_clhxj3r6pndirghkema3cc6pny	84	5	methodology	methodology	NN
work_clhxj3r6pndirghkema3cc6pny	84	6	would	would	MD
work_clhxj3r6pndirghkema3cc6pny	84	7	be	be	VB
work_clhxj3r6pndirghkema3cc6pny	84	8	approved	approve	VBN
work_clhxj3r6pndirghkema3cc6pny	84	9	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	84	10	sponsored	sponsor	VBN
work_clhxj3r6pndirghkema3cc6pny	84	11	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	84	12	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	84	13	insurance	insurance	NN
work_clhxj3r6pndirghkema3cc6pny	84	14	companies	company	NNS
work_clhxj3r6pndirghkema3cc6pny	84	15	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	84	16	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	84	17	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	84	18	SCD	SCD	NNP
work_clhxj3r6pndirghkema3cc6pny	84	19	.	.	.
work_clhxj3r6pndirghkema3cc6pny	85	1	In	in	IN
work_clhxj3r6pndirghkema3cc6pny	85	2	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	85	3	mean-	mean-	JJ
work_clhxj3r6pndirghkema3cc6pny	85	4	time	time	NN
work_clhxj3r6pndirghkema3cc6pny	85	5	,	,	,
work_clhxj3r6pndirghkema3cc6pny	85	6	listening	listen	VBG
work_clhxj3r6pndirghkema3cc6pny	85	7	,	,	,
work_clhxj3r6pndirghkema3cc6pny	85	8	believing	believe	VBG
work_clhxj3r6pndirghkema3cc6pny	85	9	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	85	10	respecting	respect	VBG
work_clhxj3r6pndirghkema3cc6pny	85	11	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	85	12	patient	patient	NN
work_clhxj3r6pndirghkema3cc6pny	85	13	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	85	14	sickle	sickle	NN
work_clhxj3r6pndirghkema3cc6pny	85	15	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	85	16	pain	pain	NN
work_clhxj3r6pndirghkema3cc6pny	85	17	should	should	MD
work_clhxj3r6pndirghkema3cc6pny	85	18	be	be	VB
work_clhxj3r6pndirghkema3cc6pny	85	19	maintained	maintain	VBN
work_clhxj3r6pndirghkema3cc6pny	85	20	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	85	21	now	now	RB
work_clhxj3r6pndirghkema3cc6pny	85	22	as	as	IN
work_clhxj3r6pndirghkema3cc6pny	85	23	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	85	24	approach	approach	NN
work_clhxj3r6pndirghkema3cc6pny	85	25	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	85	26	in-	in-	JJ
work_clhxj3r6pndirghkema3cc6pny	85	27	dividualized	dividualized	JJ
work_clhxj3r6pndirghkema3cc6pny	85	28	therapy	therapy	NN
work_clhxj3r6pndirghkema3cc6pny	85	29	.	.	.
work_clhxj3r6pndirghkema3cc6pny	86	1	Acknowledgement	acknowledgement	NN
work_clhxj3r6pndirghkema3cc6pny	86	2	Supported	support	VBN
work_clhxj3r6pndirghkema3cc6pny	86	3	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	86	4	part	part	NN
work_clhxj3r6pndirghkema3cc6pny	86	5	by	by	IN
work_clhxj3r6pndirghkema3cc6pny	86	6	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	86	7	adult	adult	NN
work_clhxj3r6pndirghkema3cc6pny	86	8	Sickle	Sickle	NNP
work_clhxj3r6pndirghkema3cc6pny	86	9	Cell	Cell	NNP
work_clhxj3r6pndirghkema3cc6pny	86	10	Program	Program	NNP
work_clhxj3r6pndirghkema3cc6pny	86	11	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	86	12	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	86	13	Com-	Com-	NNP
work_clhxj3r6pndirghkema3cc6pny	86	14	monwealth	monwealth	NN
work_clhxj3r6pndirghkema3cc6pny	86	15	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	86	16	Pennsylvania	Pennsylvania	NNP
work_clhxj3r6pndirghkema3cc6pny	86	17	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	86	18	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	86	19	Philadelphia	Philadelphia	NNP
work_clhxj3r6pndirghkema3cc6pny	86	20	Region	Region	NNP
work_clhxj3r6pndirghkema3cc6pny	86	21	.	.	.
work_clhxj3r6pndirghkema3cc6pny	87	1	Conflict	conflict	NN
work_clhxj3r6pndirghkema3cc6pny	87	2	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	87	3	Interest	Interest	NNP
work_clhxj3r6pndirghkema3cc6pny	87	4	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	87	5	author	author	NN
work_clhxj3r6pndirghkema3cc6pny	87	6	declares	declare	VBZ
work_clhxj3r6pndirghkema3cc6pny	87	7	no	no	DT
work_clhxj3r6pndirghkema3cc6pny	87	8	competing	compete	VBG
work_clhxj3r6pndirghkema3cc6pny	87	9	financial	financial	JJ
work_clhxj3r6pndirghkema3cc6pny	87	10	interests	interest	NNS
work_clhxj3r6pndirghkema3cc6pny	87	11	.	.	.
work_clhxj3r6pndirghkema3cc6pny	88	1	References	reference	NNS
work_clhxj3r6pndirghkema3cc6pny	88	2	1	1	CD
work_clhxj3r6pndirghkema3cc6pny	88	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	89	1	Ballas	Ballas	NNP
work_clhxj3r6pndirghkema3cc6pny	89	2	SK	SK	NNP
work_clhxj3r6pndirghkema3cc6pny	89	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	90	1	Treatment	treatment	NN
work_clhxj3r6pndirghkema3cc6pny	90	2	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	90	3	pain	pain	NN
work_clhxj3r6pndirghkema3cc6pny	90	4	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	90	5	adults	adult	NNS
work_clhxj3r6pndirghkema3cc6pny	90	6	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	90	7	sickle	sickle	NN
work_clhxj3r6pndirghkema3cc6pny	90	8	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	90	9	disease	disease	NN
work_clhxj3r6pndirghkema3cc6pny	90	10	.	.	.
work_clhxj3r6pndirghkema3cc6pny	91	1	Am	Am	NNP
work_clhxj3r6pndirghkema3cc6pny	91	2	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	91	3	Hematol	Hematol	NNP
work_clhxj3r6pndirghkema3cc6pny	91	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	92	1	1990;34(1):49	1990;34(1):49	CD
work_clhxj3r6pndirghkema3cc6pny	92	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	92	3	54	54	CD
work_clhxj3r6pndirghkema3cc6pny	92	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	93	1	2	2	LS
work_clhxj3r6pndirghkema3cc6pny	93	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	94	1	Pert	Pert	NNP
work_clhxj3r6pndirghkema3cc6pny	94	2	CB	CB	NNP
work_clhxj3r6pndirghkema3cc6pny	94	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	94	4	Snyder	Snyder	NNP
work_clhxj3r6pndirghkema3cc6pny	94	5	SH	SH	NNP
work_clhxj3r6pndirghkema3cc6pny	94	6	.	.	.
work_clhxj3r6pndirghkema3cc6pny	95	1	Opiate	Opiate	NNP
work_clhxj3r6pndirghkema3cc6pny	95	2	receptor	receptor	NN
work_clhxj3r6pndirghkema3cc6pny	95	3	:	:	:
work_clhxj3r6pndirghkema3cc6pny	95	4	demonstration	demonstration	NN
work_clhxj3r6pndirghkema3cc6pny	95	5	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	95	6	nervous	nervous	JJ
work_clhxj3r6pndirghkema3cc6pny	95	7	tissue	tissue	NN
work_clhxj3r6pndirghkema3cc6pny	95	8	.	.	.
work_clhxj3r6pndirghkema3cc6pny	96	1	Science	science	NN
work_clhxj3r6pndirghkema3cc6pny	96	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	97	1	1973;179(4077):1011	1973;179(4077):1011	NNP
work_clhxj3r6pndirghkema3cc6pny	97	2	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	97	3	1014	1014	CD
work_clhxj3r6pndirghkema3cc6pny	97	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	98	1	3	3	LS
work_clhxj3r6pndirghkema3cc6pny	98	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	99	1	Beckett	Beckett	NNP
work_clhxj3r6pndirghkema3cc6pny	99	2	AH	AH	NNP
work_clhxj3r6pndirghkema3cc6pny	99	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	99	4	Casy	Casy	NNP
work_clhxj3r6pndirghkema3cc6pny	99	5	AF	AF	NNP
work_clhxj3r6pndirghkema3cc6pny	99	6	.	.	.
work_clhxj3r6pndirghkema3cc6pny	100	1	Synthetic	synthetic	JJ
work_clhxj3r6pndirghkema3cc6pny	100	2	analgesics	analgesic	NNS
work_clhxj3r6pndirghkema3cc6pny	100	3	:	:	:
work_clhxj3r6pndirghkema3cc6pny	100	4	stereochemi-	stereochemi-	NN
work_clhxj3r6pndirghkema3cc6pny	100	5	cal	cal	NN
work_clhxj3r6pndirghkema3cc6pny	100	6	considerations	consideration	NNS
work_clhxj3r6pndirghkema3cc6pny	100	7	.	.	.
work_clhxj3r6pndirghkema3cc6pny	101	1	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	101	2	Pharm	Pharm	NNP
work_clhxj3r6pndirghkema3cc6pny	101	3	Pharmacol	Pharmacol	NNP
work_clhxj3r6pndirghkema3cc6pny	101	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	102	1	1954;6(12):986-	1954;6(12):986-	CD
work_clhxj3r6pndirghkema3cc6pny	102	2	1001	1001	CD
work_clhxj3r6pndirghkema3cc6pny	102	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	103	1	4	4	LS
work_clhxj3r6pndirghkema3cc6pny	103	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	104	1	Snyder	Snyder	NNP
work_clhxj3r6pndirghkema3cc6pny	104	2	SH	SH	NNP
work_clhxj3r6pndirghkema3cc6pny	104	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	105	1	Drug	drug	NN
work_clhxj3r6pndirghkema3cc6pny	105	2	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	105	3	neurotransmitter	neurotransmitter	NN
work_clhxj3r6pndirghkema3cc6pny	105	4	receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	105	5	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	105	6	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	105	7	brain	brain	NN
work_clhxj3r6pndirghkema3cc6pny	105	8	.	.	.
work_clhxj3r6pndirghkema3cc6pny	106	1	Science	science	NN
work_clhxj3r6pndirghkema3cc6pny	106	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	107	1	1984;224(4644):22	1984;224(4644):22	LS
work_clhxj3r6pndirghkema3cc6pny	107	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	107	3	31	31	CD
work_clhxj3r6pndirghkema3cc6pny	107	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	108	1	5	5	CD
work_clhxj3r6pndirghkema3cc6pny	108	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	109	1	Waldhoer	Waldhoer	NNP
work_clhxj3r6pndirghkema3cc6pny	109	2	M	M	NNP
work_clhxj3r6pndirghkema3cc6pny	109	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	109	4	Bartlett	Bartlett	NNP
work_clhxj3r6pndirghkema3cc6pny	109	5	SE	SE	NNP
work_clhxj3r6pndirghkema3cc6pny	109	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	109	7	Whistler	Whistler	NNP
work_clhxj3r6pndirghkema3cc6pny	109	8	JL	JL	NNP
work_clhxj3r6pndirghkema3cc6pny	109	9	.	.	.
work_clhxj3r6pndirghkema3cc6pny	110	1	Opioid	opioid	JJ
work_clhxj3r6pndirghkema3cc6pny	110	2	receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	110	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	111	1	Annu	Annu	NNP
work_clhxj3r6pndirghkema3cc6pny	111	2	Rev	Rev	NNP
work_clhxj3r6pndirghkema3cc6pny	111	3	Biochem	Biochem	NNP
work_clhxj3r6pndirghkema3cc6pny	111	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	112	1	2004;73:953	2004;73:953	CD
work_clhxj3r6pndirghkema3cc6pny	112	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	112	3	990	990	CD
work_clhxj3r6pndirghkema3cc6pny	112	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	113	1	6	6	CD
work_clhxj3r6pndirghkema3cc6pny	113	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	114	1	Cox	Cox	NNP
work_clhxj3r6pndirghkema3cc6pny	114	2	BM	BM	NNP
work_clhxj3r6pndirghkema3cc6pny	114	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	115	1	Recent	recent	JJ
work_clhxj3r6pndirghkema3cc6pny	115	2	developments	development	NNS
work_clhxj3r6pndirghkema3cc6pny	115	3	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	115	4	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	115	5	study	study	NN
work_clhxj3r6pndirghkema3cc6pny	115	6	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	115	7	opioid	opioid	NNP
work_clhxj3r6pndirghkema3cc6pny	115	8	re-	re-	JJ
work_clhxj3r6pndirghkema3cc6pny	115	9	ceptors	ceptor	NNS
work_clhxj3r6pndirghkema3cc6pny	115	10	.	.	.
work_clhxj3r6pndirghkema3cc6pny	116	1	Mol	Mol	NNP
work_clhxj3r6pndirghkema3cc6pny	116	2	Pharmacol	Pharmacol	NNP
work_clhxj3r6pndirghkema3cc6pny	116	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	117	1	2013;83(4):723	2013;83(4):723	CD
work_clhxj3r6pndirghkema3cc6pny	117	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	117	3	728	728	CD
work_clhxj3r6pndirghkema3cc6pny	117	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	118	1	7	7	LS
work_clhxj3r6pndirghkema3cc6pny	118	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	119	1	Granier	Granier	NNP
work_clhxj3r6pndirghkema3cc6pny	119	2	S	S	NNP
work_clhxj3r6pndirghkema3cc6pny	119	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	119	4	Manglik	Manglik	NNP
work_clhxj3r6pndirghkema3cc6pny	119	5	A	A	NNP
work_clhxj3r6pndirghkema3cc6pny	119	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	119	7	Kruse	Kruse	NNP
work_clhxj3r6pndirghkema3cc6pny	119	8	AC	AC	NNP
work_clhxj3r6pndirghkema3cc6pny	119	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	119	10	Kobilka	Kobilka	NNP
work_clhxj3r6pndirghkema3cc6pny	119	11	TS	TS	NNP
work_clhxj3r6pndirghkema3cc6pny	119	12	,	,	,
work_clhxj3r6pndirghkema3cc6pny	119	13	Thian	Thian	NNP
work_clhxj3r6pndirghkema3cc6pny	119	14	FS	FS	NNP
work_clhxj3r6pndirghkema3cc6pny	119	15	,	,	,
work_clhxj3r6pndirghkema3cc6pny	119	16	Weis	Weis	NNP
work_clhxj3r6pndirghkema3cc6pny	119	17	WI	WI	NNP
work_clhxj3r6pndirghkema3cc6pny	119	18	,	,	,
work_clhxj3r6pndirghkema3cc6pny	119	19	Kobilka	Kobilka	NNP
work_clhxj3r6pndirghkema3cc6pny	119	20	BK	BK	NNP
work_clhxj3r6pndirghkema3cc6pny	119	21	.	.	.
work_clhxj3r6pndirghkema3cc6pny	120	1	Structure	structure	NN
work_clhxj3r6pndirghkema3cc6pny	120	2	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	120	3	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	120	4	delta	delta	NN
work_clhxj3r6pndirghkema3cc6pny	120	5	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	120	6	opioid	opioid	NN
work_clhxj3r6pndirghkema3cc6pny	120	7	re-	re-	JJ
work_clhxj3r6pndirghkema3cc6pny	120	8	ceptor	ceptor	NN
work_clhxj3r6pndirghkema3cc6pny	120	9	bound	bind	VBN
work_clhxj3r6pndirghkema3cc6pny	120	10	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	120	11	naltrindole	naltrindole	NNP
work_clhxj3r6pndirghkema3cc6pny	120	12	.	.	.
work_clhxj3r6pndirghkema3cc6pny	121	1	Nature	nature	NN
work_clhxj3r6pndirghkema3cc6pny	121	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	122	1	2012;485(7398):400-	2012;485(7398):400-	CD
work_clhxj3r6pndirghkema3cc6pny	122	2	404	404	CD
work_clhxj3r6pndirghkema3cc6pny	122	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	123	1	8	8	LS
work_clhxj3r6pndirghkema3cc6pny	123	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	124	1	Manglik	Manglik	NNP
work_clhxj3r6pndirghkema3cc6pny	124	2	A	A	NNP
work_clhxj3r6pndirghkema3cc6pny	124	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	124	4	Kruse	Kruse	NNP
work_clhxj3r6pndirghkema3cc6pny	124	5	AC	AC	NNP
work_clhxj3r6pndirghkema3cc6pny	124	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	124	7	Kobilka	Kobilka	NNP
work_clhxj3r6pndirghkema3cc6pny	124	8	TS	TS	NNP
work_clhxj3r6pndirghkema3cc6pny	124	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	124	10	Thian	Thian	NNP
work_clhxj3r6pndirghkema3cc6pny	124	11	FS	FS	NNP
work_clhxj3r6pndirghkema3cc6pny	124	12	,	,	,
work_clhxj3r6pndirghkema3cc6pny	124	13	Mathiesen	Mathiesen	NNP
work_clhxj3r6pndirghkema3cc6pny	124	14	JM	JM	NNP
work_clhxj3r6pndirghkema3cc6pny	124	15	,	,	,
work_clhxj3r6pndirghkema3cc6pny	124	16	Sunahara	Sunahara	NNP
work_clhxj3r6pndirghkema3cc6pny	124	17	RK	RK	NNP
work_clhxj3r6pndirghkema3cc6pny	124	18	,	,	,
work_clhxj3r6pndirghkema3cc6pny	124	19	Pardo	Pardo	NNP
work_clhxj3r6pndirghkema3cc6pny	124	20	L	L	NNP
work_clhxj3r6pndirghkema3cc6pny	124	21	,	,	,
work_clhxj3r6pndirghkema3cc6pny	124	22	et	et	NNP
work_clhxj3r6pndirghkema3cc6pny	124	23	al	al	NNP
work_clhxj3r6pndirghkema3cc6pny	124	24	.	.	.
work_clhxj3r6pndirghkema3cc6pny	125	1	Crystal	crystal	JJ
work_clhxj3r6pndirghkema3cc6pny	125	2	structure	structure	NN
work_clhxj3r6pndirghkema3cc6pny	125	3	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	125	4	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	125	5	micro	micro	JJ
work_clhxj3r6pndirghkema3cc6pny	125	6	-	-	JJ
work_clhxj3r6pndirghkema3cc6pny	125	7	opioid	opioid	JJ
work_clhxj3r6pndirghkema3cc6pny	125	8	receptor	receptor	NN
work_clhxj3r6pndirghkema3cc6pny	125	9	bound	bind	VBN
work_clhxj3r6pndirghkema3cc6pny	125	10	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	125	11	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	125	12	morphinan	morphinan	NN
work_clhxj3r6pndirghkema3cc6pny	125	13	antagonist	antagonist	NN
work_clhxj3r6pndirghkema3cc6pny	125	14	.	.	.
work_clhxj3r6pndirghkema3cc6pny	126	1	Nature	nature	NN
work_clhxj3r6pndirghkema3cc6pny	126	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	127	1	2012;485(7398):321	2012;485(7398):321	CD
work_clhxj3r6pndirghkema3cc6pny	127	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	127	3	326	326	CD
work_clhxj3r6pndirghkema3cc6pny	127	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	128	1	9	9	CD
work_clhxj3r6pndirghkema3cc6pny	128	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	129	1	Thompson	Thompson	NNP
work_clhxj3r6pndirghkema3cc6pny	129	2	AA	AA	NNP
work_clhxj3r6pndirghkema3cc6pny	129	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	129	4	Liu	Liu	NNP
work_clhxj3r6pndirghkema3cc6pny	129	5	W	W	NNP
work_clhxj3r6pndirghkema3cc6pny	129	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	129	7	Chun	Chun	NNP
work_clhxj3r6pndirghkema3cc6pny	129	8	E	E	NNP
work_clhxj3r6pndirghkema3cc6pny	129	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	129	10	Katritch	Katritch	NNP
work_clhxj3r6pndirghkema3cc6pny	129	11	V	V	NNP
work_clhxj3r6pndirghkema3cc6pny	129	12	,	,	,
work_clhxj3r6pndirghkema3cc6pny	129	13	Wu	Wu	NNP
work_clhxj3r6pndirghkema3cc6pny	129	14	H	H	NNP
work_clhxj3r6pndirghkema3cc6pny	129	15	,	,	,
work_clhxj3r6pndirghkema3cc6pny	129	16	Vardy	Vardy	NNP
work_clhxj3r6pndirghkema3cc6pny	129	17	E	E	NNP
work_clhxj3r6pndirghkema3cc6pny	129	18	,	,	,
work_clhxj3r6pndirghkema3cc6pny	129	19	Huang	Huang	NNP
work_clhxj3r6pndirghkema3cc6pny	129	20	XP	XP	NNP
work_clhxj3r6pndirghkema3cc6pny	129	21	,	,	,
work_clhxj3r6pndirghkema3cc6pny	129	22	et	et	NNP
work_clhxj3r6pndirghkema3cc6pny	129	23	al	al	NNP
work_clhxj3r6pndirghkema3cc6pny	129	24	.	.	.
work_clhxj3r6pndirghkema3cc6pny	130	1	Structure	structure	NN
work_clhxj3r6pndirghkema3cc6pny	130	2	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	130	3	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	130	4	nociceptin	nociceptin	NN
work_clhxj3r6pndirghkema3cc6pny	130	5	/	/	SYM
work_clhxj3r6pndirghkema3cc6pny	130	6	orphanin	orphanin	NNP
work_clhxj3r6pndirghkema3cc6pny	130	7	FQ	FQ	NNP
work_clhxj3r6pndirghkema3cc6pny	130	8	receptor	receptor	NN
work_clhxj3r6pndirghkema3cc6pny	130	9	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	130	10	complex	complex	NN
work_clhxj3r6pndirghkema3cc6pny	130	11	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	130	12	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	130	13	peptide	peptide	JJ
work_clhxj3r6pndirghkema3cc6pny	130	14	mimetic	mimetic	JJ
work_clhxj3r6pndirghkema3cc6pny	130	15	.	.	.
work_clhxj3r6pndirghkema3cc6pny	131	1	Nature	nature	NN
work_clhxj3r6pndirghkema3cc6pny	131	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	132	1	2012;485(7398):395	2012;485(7398):395	CD
work_clhxj3r6pndirghkema3cc6pny	132	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	132	3	399	399	CD
work_clhxj3r6pndirghkema3cc6pny	132	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	133	1	10	10	CD
work_clhxj3r6pndirghkema3cc6pny	133	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	134	1	Wu	Wu	NNP
work_clhxj3r6pndirghkema3cc6pny	134	2	H	H	NNP
work_clhxj3r6pndirghkema3cc6pny	134	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	134	4	Wacker	Wacker	NNP
work_clhxj3r6pndirghkema3cc6pny	134	5	D	D	NNP
work_clhxj3r6pndirghkema3cc6pny	134	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	134	7	Mileni	Mileni	NNP
work_clhxj3r6pndirghkema3cc6pny	134	8	M	M	NNP
work_clhxj3r6pndirghkema3cc6pny	134	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	134	10	Katritch	Katritch	NNP
work_clhxj3r6pndirghkema3cc6pny	134	11	V	V	NNP
work_clhxj3r6pndirghkema3cc6pny	134	12	,	,	,
work_clhxj3r6pndirghkema3cc6pny	134	13	Han	Han	NNP
work_clhxj3r6pndirghkema3cc6pny	134	14	GW	GW	NNP
work_clhxj3r6pndirghkema3cc6pny	134	15	,	,	,
work_clhxj3r6pndirghkema3cc6pny	134	16	Vardy	Vardy	NNP
work_clhxj3r6pndirghkema3cc6pny	134	17	E	E	NNP
work_clhxj3r6pndirghkema3cc6pny	134	18	,	,	,
work_clhxj3r6pndirghkema3cc6pny	134	19	Liu	Liu	NNP
work_clhxj3r6pndirghkema3cc6pny	134	20	W	W	NNP
work_clhxj3r6pndirghkema3cc6pny	134	21	,	,	,
work_clhxj3r6pndirghkema3cc6pny	134	22	et	et	NNP
work_clhxj3r6pndirghkema3cc6pny	134	23	al	al	NNP
work_clhxj3r6pndirghkema3cc6pny	134	24	.	.	.
work_clhxj3r6pndirghkema3cc6pny	135	1	Structure	structure	NN
work_clhxj3r6pndirghkema3cc6pny	135	2	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	135	3	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	135	4	human	human	JJ
work_clhxj3r6pndirghkema3cc6pny	135	5	kappa	kappa	NNP
work_clhxj3r6pndirghkema3cc6pny	135	6	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	135	7	opioid	opioid	NN
work_clhxj3r6pndirghkema3cc6pny	135	8	recep-	recep-	NN
work_clhxj3r6pndirghkema3cc6pny	135	9	tor	tor	NN
work_clhxj3r6pndirghkema3cc6pny	135	10	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	135	11	complex	complex	NN
work_clhxj3r6pndirghkema3cc6pny	135	12	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	135	13	JDTic	JDTic	NNP
work_clhxj3r6pndirghkema3cc6pny	135	14	.	.	.
work_clhxj3r6pndirghkema3cc6pny	136	1	Nature	nature	NN
work_clhxj3r6pndirghkema3cc6pny	136	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	137	1	2012;485(7398):327-	2012;485(7398):327-	CD
work_clhxj3r6pndirghkema3cc6pny	137	2	332	332	CD
work_clhxj3r6pndirghkema3cc6pny	137	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	138	1	11	11	CD
work_clhxj3r6pndirghkema3cc6pny	138	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	139	1	Leysen	Leysen	NNP
work_clhxj3r6pndirghkema3cc6pny	139	2	JE	JE	NNP
work_clhxj3r6pndirghkema3cc6pny	139	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	139	4	Gommeren	Gommeren	NNP
work_clhxj3r6pndirghkema3cc6pny	139	5	W	W	NNP
work_clhxj3r6pndirghkema3cc6pny	139	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	139	7	Niemegeers	Niemegeers	NNPS
work_clhxj3r6pndirghkema3cc6pny	139	8	CJ	CJ	NNP
work_clhxj3r6pndirghkema3cc6pny	139	9	.	.	.
work_clhxj3r6pndirghkema3cc6pny	140	1	[	[	-LRB-
work_clhxj3r6pndirghkema3cc6pny	140	2	3H]Sufen-	3h]sufen-	CD
work_clhxj3r6pndirghkema3cc6pny	140	3	tanil	tanil	NN
work_clhxj3r6pndirghkema3cc6pny	140	4	,	,	,
work_clhxj3r6pndirghkema3cc6pny	140	5	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	140	6	superior	superior	JJ
work_clhxj3r6pndirghkema3cc6pny	140	7	ligand	ligand	NN
work_clhxj3r6pndirghkema3cc6pny	140	8	for	for	IN
work_clhxj3r6pndirghkema3cc6pny	140	9	mu	mu	NNP
work_clhxj3r6pndirghkema3cc6pny	140	10	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	140	11	opiate	opiate	NNP
work_clhxj3r6pndirghkema3cc6pny	140	12	receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	140	13	:	:	:
work_clhxj3r6pndirghkema3cc6pny	140	14	binding	bind	VBG
work_clhxj3r6pndirghkema3cc6pny	140	15	properties	property	NNS
work_clhxj3r6pndirghkema3cc6pny	140	16	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	140	17	regional	regional	JJ
work_clhxj3r6pndirghkema3cc6pny	140	18	distribution	distribution	NN
work_clhxj3r6pndirghkema3cc6pny	140	19	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	140	20	rat	rat	NN
work_clhxj3r6pndirghkema3cc6pny	140	21	brain	brain	NN
work_clhxj3r6pndirghkema3cc6pny	140	22	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	140	23	spinal	spinal	JJ
work_clhxj3r6pndirghkema3cc6pny	140	24	cord	cord	NN
work_clhxj3r6pndirghkema3cc6pny	140	25	.	.	.
work_clhxj3r6pndirghkema3cc6pny	141	1	Eur	Eur	NNP
work_clhxj3r6pndirghkema3cc6pny	141	2	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	141	3	Pharmacol	Pharmacol	NNP
work_clhxj3r6pndirghkema3cc6pny	141	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	142	1	1983;87(2	1983;87(2	LS
work_clhxj3r6pndirghkema3cc6pny	142	2	-	-	:
work_clhxj3r6pndirghkema3cc6pny	142	3	3):209	3):209	NN
work_clhxj3r6pndirghkema3cc6pny	142	4	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	142	5	225	225	CD
work_clhxj3r6pndirghkema3cc6pny	142	6	.	.	.
work_clhxj3r6pndirghkema3cc6pny	143	1	12	12	CD
work_clhxj3r6pndirghkema3cc6pny	143	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	144	1	Kosterlitz	Kosterlitz	NNP
work_clhxj3r6pndirghkema3cc6pny	144	2	WH	WH	NNP
work_clhxj3r6pndirghkema3cc6pny	144	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	145	1	Opiate	Opiate	NNP
work_clhxj3r6pndirghkema3cc6pny	145	2	actions	action	NNS
work_clhxj3r6pndirghkema3cc6pny	145	3	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	145	4	guinea	guinea	NNP
work_clhxj3r6pndirghkema3cc6pny	145	5	pig	pig	NNP
work_clhxj3r6pndirghkema3cc6pny	145	6	ileum	ileum	NNP
work_clhxj3r6pndirghkema3cc6pny	145	7	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	145	8	mouse	mouse	NNP
work_clhxj3r6pndirghkema3cc6pny	145	9	vas	vas	NNP
work_clhxj3r6pndirghkema3cc6pny	145	10	deferens	deferens	NNP
work_clhxj3r6pndirghkema3cc6pny	145	11	.	.	.
work_clhxj3r6pndirghkema3cc6pny	146	1	Neurosci	Neurosci	NNP
work_clhxj3r6pndirghkema3cc6pny	146	2	Res	Res	NNP
work_clhxj3r6pndirghkema3cc6pny	146	3	Bull	Bull	NNP
work_clhxj3r6pndirghkema3cc6pny	146	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	147	1	1975:13:68	1975:13:68	CD
work_clhxj3r6pndirghkema3cc6pny	147	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	147	3	70	70	CD
work_clhxj3r6pndirghkema3cc6pny	147	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	148	1	13	13	CD
work_clhxj3r6pndirghkema3cc6pny	148	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	149	1	Martin	Martin	NNP
work_clhxj3r6pndirghkema3cc6pny	149	2	WR	WR	NNP
work_clhxj3r6pndirghkema3cc6pny	149	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	149	4	Eades	Eades	NNP
work_clhxj3r6pndirghkema3cc6pny	149	5	CG	CG	NNP
work_clhxj3r6pndirghkema3cc6pny	149	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	149	7	Thompson	Thompson	NNP
work_clhxj3r6pndirghkema3cc6pny	149	8	JA	JA	NNP
work_clhxj3r6pndirghkema3cc6pny	149	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	149	10	Huppler	Huppler	NNP
work_clhxj3r6pndirghkema3cc6pny	149	11	RE	RE	NNP
work_clhxj3r6pndirghkema3cc6pny	149	12	,	,	,
work_clhxj3r6pndirghkema3cc6pny	149	13	Gilbert	Gilbert	NNP
work_clhxj3r6pndirghkema3cc6pny	149	14	PE	PE	NNP
work_clhxj3r6pndirghkema3cc6pny	149	15	.	.	.
work_clhxj3r6pndirghkema3cc6pny	150	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	150	2	effects	effect	NNS
work_clhxj3r6pndirghkema3cc6pny	150	3	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	150	4	morphine-	morphine-	NN
work_clhxj3r6pndirghkema3cc6pny	150	5	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	150	6	nalorphine-	nalorphine-	NN
work_clhxj3r6pndirghkema3cc6pny	150	7	like	like	IN
work_clhxj3r6pndirghkema3cc6pny	150	8	drugs	drug	NNS
work_clhxj3r6pndirghkema3cc6pny	150	9	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	150	10	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	150	11	nondependent	nondependent	NN
work_clhxj3r6pndirghkema3cc6pny	150	12	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	150	13	morphine	morphine	NN
work_clhxj3r6pndirghkema3cc6pny	150	14	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	150	15	dependent	dependent	JJ
work_clhxj3r6pndirghkema3cc6pny	150	16	chronic	chronic	JJ
work_clhxj3r6pndirghkema3cc6pny	150	17	spinal	spinal	JJ
work_clhxj3r6pndirghkema3cc6pny	150	18	dog	dog	NN
work_clhxj3r6pndirghkema3cc6pny	150	19	.	.	.
work_clhxj3r6pndirghkema3cc6pny	151	1	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	151	2	Pharmacol	Pharmacol	NNP
work_clhxj3r6pndirghkema3cc6pny	151	3	Exp	Exp	NNP
work_clhxj3r6pndirghkema3cc6pny	151	4	Ther	Ther	NNP
work_clhxj3r6pndirghkema3cc6pny	151	5	.	.	.
work_clhxj3r6pndirghkema3cc6pny	152	1	1976;197(3):517	1976;197(3):517	NNP
work_clhxj3r6pndirghkema3cc6pny	152	2	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	152	3	532	532	CD
work_clhxj3r6pndirghkema3cc6pny	152	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	153	1	14	14	CD
work_clhxj3r6pndirghkema3cc6pny	153	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	154	1	Herz	Herz	NNP
work_clhxj3r6pndirghkema3cc6pny	154	2	A	A	NNP
work_clhxj3r6pndirghkema3cc6pny	154	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	154	4	Teschemacher	Teschemacher	NNP
work_clhxj3r6pndirghkema3cc6pny	154	5	HJ	HJ	NNP
work_clhxj3r6pndirghkema3cc6pny	154	6	.	.	.
work_clhxj3r6pndirghkema3cc6pny	155	1	Activities	activity	NNS
work_clhxj3r6pndirghkema3cc6pny	155	2	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	155	3	sites	site	NNS
work_clhxj3r6pndirghkema3cc6pny	155	4	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	155	5	antino-	antino-	NN
work_clhxj3r6pndirghkema3cc6pny	155	6	ciceptive	ciceptive	JJ
work_clhxj3r6pndirghkema3cc6pny	155	7	action	action	NN
work_clhxj3r6pndirghkema3cc6pny	155	8	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	155	9	morphine	morphine	NN
work_clhxj3r6pndirghkema3cc6pny	155	10	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	155	11	like	like	JJ
work_clhxj3r6pndirghkema3cc6pny	155	12	analgesics	analgesic	NNS
work_clhxj3r6pndirghkema3cc6pny	155	13	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	155	14	kinetics	kinetic	NNS
work_clhxj3r6pndirghkema3cc6pny	155	15	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	155	16	distribution	distribution	NN
work_clhxj3r6pndirghkema3cc6pny	155	17	following	follow	VBG
work_clhxj3r6pndirghkema3cc6pny	155	18	intravenous	intravenous	JJ
work_clhxj3r6pndirghkema3cc6pny	155	19	intracerebral	intracerebral	JJ
work_clhxj3r6pndirghkema3cc6pny	155	20	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	155	21	intraventricular	intraventricular	JJ
work_clhxj3r6pndirghkema3cc6pny	155	22	application	application	NN
work_clhxj3r6pndirghkema3cc6pny	155	23	.	.	.
work_clhxj3r6pndirghkema3cc6pny	156	1	Adv	Adv	NNP
work_clhxj3r6pndirghkema3cc6pny	156	2	Drug	Drug	NNP
work_clhxj3r6pndirghkema3cc6pny	156	3	Res	Res	NNP
work_clhxj3r6pndirghkema3cc6pny	156	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	157	1	1971:6:79	1971:6:79	CD
work_clhxj3r6pndirghkema3cc6pny	157	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	158	1	15	15	CD
work_clhxj3r6pndirghkema3cc6pny	158	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	159	1	Simon	Simon	NNP
work_clhxj3r6pndirghkema3cc6pny	159	2	EJ	EJ	NNP
work_clhxj3r6pndirghkema3cc6pny	159	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	159	4	Hiller	Hiller	NNP
work_clhxj3r6pndirghkema3cc6pny	159	5	JM	JM	NNP
work_clhxj3r6pndirghkema3cc6pny	159	6	.	.	.
work_clhxj3r6pndirghkema3cc6pny	160	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	160	2	opiate	opiate	NN
work_clhxj3r6pndirghkema3cc6pny	160	3	receptors	receptor	VBZ
work_clhxj3r6pndirghkema3cc6pny	160	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	161	1	Annu	Annu	NNP
work_clhxj3r6pndirghkema3cc6pny	161	2	Rev	Rev	NNP
work_clhxj3r6pndirghkema3cc6pny	161	3	Pharmacol	Pharmacol	NNP
work_clhxj3r6pndirghkema3cc6pny	161	4	Toxicol	Toxicol	NNP
work_clhxj3r6pndirghkema3cc6pny	161	5	.	.	.
work_clhxj3r6pndirghkema3cc6pny	162	1	1978;18:371	1978;18:371	CD
work_clhxj3r6pndirghkema3cc6pny	162	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	162	3	394	394	CD
work_clhxj3r6pndirghkema3cc6pny	162	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	163	1	16	16	CD
work_clhxj3r6pndirghkema3cc6pny	163	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	164	1	Snyder	Snyder	NNP
work_clhxj3r6pndirghkema3cc6pny	164	2	SH	SH	NNP
work_clhxj3r6pndirghkema3cc6pny	164	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	165	1	Opiate	Opiate	NNP
work_clhxj3r6pndirghkema3cc6pny	165	2	receptors	receptor	NNS
work_clhxj3r6pndirghkema3cc6pny	165	3	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	165	4	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	165	5	brain	brain	NN
work_clhxj3r6pndirghkema3cc6pny	165	6	.	.	.
work_clhxj3r6pndirghkema3cc6pny	166	1	N	N	NNP
work_clhxj3r6pndirghkema3cc6pny	166	2	Engl	Engl	NNP
work_clhxj3r6pndirghkema3cc6pny	166	3	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	166	4	Med	Med	NNP
work_clhxj3r6pndirghkema3cc6pny	166	5	.	.	.
work_clhxj3r6pndirghkema3cc6pny	167	1	1977;296(5):266	1977;296(5):266	NNP
work_clhxj3r6pndirghkema3cc6pny	167	2	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	167	3	271	271	CD
work_clhxj3r6pndirghkema3cc6pny	167	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	168	1	17	17	CD
work_clhxj3r6pndirghkema3cc6pny	168	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	169	1	Ballas	Ballas	NNP
work_clhxj3r6pndirghkema3cc6pny	169	2	SK	SK	NNP
work_clhxj3r6pndirghkema3cc6pny	169	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	170	1	Pathophysiology	pathophysiology	NN
work_clhxj3r6pndirghkema3cc6pny	170	2	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	170	3	principles	principle	NNS
work_clhxj3r6pndirghkema3cc6pny	170	4	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	170	5	manage-	manage-	JJ
work_clhxj3r6pndirghkema3cc6pny	170	6	ment	ment	NN
work_clhxj3r6pndirghkema3cc6pny	170	7	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	170	8	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	170	9	many	many	JJ
work_clhxj3r6pndirghkema3cc6pny	170	10	faces	face	NNS
work_clhxj3r6pndirghkema3cc6pny	170	11	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	170	12	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	170	13	acute	acute	JJ
work_clhxj3r6pndirghkema3cc6pny	170	14	vaso	vaso	JJ
work_clhxj3r6pndirghkema3cc6pny	170	15	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	170	16	occlusive	occlusive	JJ
work_clhxj3r6pndirghkema3cc6pny	170	17	cri-	cri-	JJ
work_clhxj3r6pndirghkema3cc6pny	170	18	sis	sis	NN
work_clhxj3r6pndirghkema3cc6pny	170	19	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	170	20	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	170	21	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	170	22	sickle	sickle	NN
work_clhxj3r6pndirghkema3cc6pny	170	23	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	170	24	disease	disease	NN
work_clhxj3r6pndirghkema3cc6pny	170	25	.	.	.
work_clhxj3r6pndirghkema3cc6pny	171	1	Eur	Eur	NNP
work_clhxj3r6pndirghkema3cc6pny	171	2	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	171	3	Haematol	Haematol	NNP
work_clhxj3r6pndirghkema3cc6pny	171	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	172	1	2015;95(2):113	2015;95(2):113	CD
work_clhxj3r6pndirghkema3cc6pny	172	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	172	3	123	123	CD
work_clhxj3r6pndirghkema3cc6pny	172	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	173	1	Articles	article	NNS
work_clhxj3r6pndirghkema3cc6pny	173	2	©	©	NNP
work_clhxj3r6pndirghkema3cc6pny	173	3	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	173	4	authors	author	NNS
work_clhxj3r6pndirghkema3cc6pny	173	5	|	|	NNP
work_clhxj3r6pndirghkema3cc6pny	173	6	Journal	Journal	NNP
work_clhxj3r6pndirghkema3cc6pny	173	7	compilation	compilation	NN
work_clhxj3r6pndirghkema3cc6pny	173	8	©	©	NNP
work_clhxj3r6pndirghkema3cc6pny	173	9	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	173	10	Clin	Clin	NNP
work_clhxj3r6pndirghkema3cc6pny	173	11	Med	Med	NNP
work_clhxj3r6pndirghkema3cc6pny	173	12	Res	Res	NNP
work_clhxj3r6pndirghkema3cc6pny	173	13	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	173	14	Elmer	Elmer	NNP
work_clhxj3r6pndirghkema3cc6pny	173	15	Press	Press	NNP
work_clhxj3r6pndirghkema3cc6pny	173	16	Inc	Inc	NNP
work_clhxj3r6pndirghkema3cc6pny	173	17	™	™	CD
work_clhxj3r6pndirghkema3cc6pny	173	18	|	|	NNP
work_clhxj3r6pndirghkema3cc6pny	173	19	www.jocmr.org360	www.jocmr.org360	NNP
work_clhxj3r6pndirghkema3cc6pny	173	20	Management	Management	NNP
work_clhxj3r6pndirghkema3cc6pny	173	21	Evolution	Evolution	NNP
work_clhxj3r6pndirghkema3cc6pny	173	22	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	173	23	Sickle	Sickle	NNP
work_clhxj3r6pndirghkema3cc6pny	173	24	Cell	Cell	NNP
work_clhxj3r6pndirghkema3cc6pny	173	25	Pain	Pain	NNP
work_clhxj3r6pndirghkema3cc6pny	173	26	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	173	27	Clin	Clin	NNP
work_clhxj3r6pndirghkema3cc6pny	173	28	Med	Med	NNP
work_clhxj3r6pndirghkema3cc6pny	173	29	Res	Res	NNP
work_clhxj3r6pndirghkema3cc6pny	173	30	.	.	.
work_clhxj3r6pndirghkema3cc6pny	174	1	2016;8(5):357	2016;8(5):357	CD
work_clhxj3r6pndirghkema3cc6pny	174	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	174	3	360	360	CD
work_clhxj3r6pndirghkema3cc6pny	174	4	18	18	CD
work_clhxj3r6pndirghkema3cc6pny	174	5	.	.	.
work_clhxj3r6pndirghkema3cc6pny	175	1	Hollenberg	Hollenberg	NNP
work_clhxj3r6pndirghkema3cc6pny	175	2	PF	PF	NNP
work_clhxj3r6pndirghkema3cc6pny	175	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	176	1	Characteristics	characteristic	NNS
work_clhxj3r6pndirghkema3cc6pny	176	2	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	176	3	common	common	JJ
work_clhxj3r6pndirghkema3cc6pny	176	4	properties	property	NNS
work_clhxj3r6pndirghkema3cc6pny	176	5	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	176	6	inhibitors	inhibitor	NNS
work_clhxj3r6pndirghkema3cc6pny	176	7	,	,	,
work_clhxj3r6pndirghkema3cc6pny	176	8	inducers	inducer	NNS
work_clhxj3r6pndirghkema3cc6pny	176	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	176	10	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	176	11	activators	activator	NNS
work_clhxj3r6pndirghkema3cc6pny	176	12	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	176	13	CYP	CYP	NNP
work_clhxj3r6pndirghkema3cc6pny	176	14	enzymes	enzyme	NNS
work_clhxj3r6pndirghkema3cc6pny	176	15	.	.	.
work_clhxj3r6pndirghkema3cc6pny	177	1	Drug	Drug	NNP
work_clhxj3r6pndirghkema3cc6pny	177	2	Metab	Metab	NNP
work_clhxj3r6pndirghkema3cc6pny	177	3	Rev.	Rev.	NNP
work_clhxj3r6pndirghkema3cc6pny	178	1	2002;34(1	2002;34(1	LS
work_clhxj3r6pndirghkema3cc6pny	178	2	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	178	3	2):17	2):17	CD
work_clhxj3r6pndirghkema3cc6pny	178	4	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	178	5	35	35	CD
work_clhxj3r6pndirghkema3cc6pny	178	6	.	.	.
work_clhxj3r6pndirghkema3cc6pny	179	1	19	19	CD
work_clhxj3r6pndirghkema3cc6pny	179	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	180	1	Smith	Smith	NNP
work_clhxj3r6pndirghkema3cc6pny	180	2	HS	HS	NNP
work_clhxj3r6pndirghkema3cc6pny	180	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	181	1	Opioid	opioid	JJ
work_clhxj3r6pndirghkema3cc6pny	181	2	metabolism	metabolism	NN
work_clhxj3r6pndirghkema3cc6pny	181	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	182	1	Mayo	Mayo	NNP
work_clhxj3r6pndirghkema3cc6pny	182	2	Clin	Clin	NNP
work_clhxj3r6pndirghkema3cc6pny	182	3	Proc	Proc	NNP
work_clhxj3r6pndirghkema3cc6pny	182	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	183	1	2009;84(7):613	2009;84(7):613	CD
work_clhxj3r6pndirghkema3cc6pny	183	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	183	3	624	624	CD
work_clhxj3r6pndirghkema3cc6pny	183	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	184	1	20	20	CD
work_clhxj3r6pndirghkema3cc6pny	184	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	185	1	Sery	Sery	NNP
work_clhxj3r6pndirghkema3cc6pny	185	2	O	O	NNP
work_clhxj3r6pndirghkema3cc6pny	185	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	185	4	Hrazdilova	Hrazdilova	NNP
work_clhxj3r6pndirghkema3cc6pny	185	5	O	O	NNP
work_clhxj3r6pndirghkema3cc6pny	185	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	185	7	Matalova	Matalova	NNP
work_clhxj3r6pndirghkema3cc6pny	185	8	E	E	NNP
work_clhxj3r6pndirghkema3cc6pny	185	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	185	10	Sevcik	Sevcik	NNP
work_clhxj3r6pndirghkema3cc6pny	185	11	P.	P.	NNP
work_clhxj3r6pndirghkema3cc6pny	185	12	Pain	Pain	NNP
work_clhxj3r6pndirghkema3cc6pny	185	13	re-	re-	JJ
work_clhxj3r6pndirghkema3cc6pny	185	14	search	search	NN
work_clhxj3r6pndirghkema3cc6pny	185	15	update	update	NN
work_clhxj3r6pndirghkema3cc6pny	185	16	from	from	IN
work_clhxj3r6pndirghkema3cc6pny	185	17	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	185	18	genetic	genetic	JJ
work_clhxj3r6pndirghkema3cc6pny	185	19	point	point	NN
work_clhxj3r6pndirghkema3cc6pny	185	20	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	185	21	view	view	NN
work_clhxj3r6pndirghkema3cc6pny	185	22	.	.	.
work_clhxj3r6pndirghkema3cc6pny	186	1	Pain	Pain	NNP
work_clhxj3r6pndirghkema3cc6pny	186	2	Pract	Pract	NNP
work_clhxj3r6pndirghkema3cc6pny	186	3	.	.	.
work_clhxj3r6pndirghkema3cc6pny	187	1	2005;5(4):341	2005;5(4):341	CD
work_clhxj3r6pndirghkema3cc6pny	187	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	187	3	348	348	CD
work_clhxj3r6pndirghkema3cc6pny	187	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	188	1	21	21	CD
work_clhxj3r6pndirghkema3cc6pny	188	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	189	1	Shord	Shord	NNP
work_clhxj3r6pndirghkema3cc6pny	189	2	SS	SS	NNP
work_clhxj3r6pndirghkema3cc6pny	189	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	189	4	Cavallari	Cavallari	NNP
work_clhxj3r6pndirghkema3cc6pny	189	5	LH	LH	NNP
work_clhxj3r6pndirghkema3cc6pny	189	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	189	7	Gao	Gao	NNP
work_clhxj3r6pndirghkema3cc6pny	189	8	W	W	NNP
work_clhxj3r6pndirghkema3cc6pny	189	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	189	10	Jeong	Jeong	NNP
work_clhxj3r6pndirghkema3cc6pny	189	11	HY	HY	NNP
work_clhxj3r6pndirghkema3cc6pny	189	12	,	,	,
work_clhxj3r6pndirghkema3cc6pny	189	13	Deyo	Deyo	NNP
work_clhxj3r6pndirghkema3cc6pny	189	14	K	K	NNP
work_clhxj3r6pndirghkema3cc6pny	189	15	,	,	,
work_clhxj3r6pndirghkema3cc6pny	189	16	Patel	Patel	NNP
work_clhxj3r6pndirghkema3cc6pny	189	17	SR	SR	NNP
work_clhxj3r6pndirghkema3cc6pny	189	18	,	,	,
work_clhxj3r6pndirghkema3cc6pny	189	19	Camp	Camp	NNP
work_clhxj3r6pndirghkema3cc6pny	189	20	JR	JR	NNP
work_clhxj3r6pndirghkema3cc6pny	189	21	,	,	,
work_clhxj3r6pndirghkema3cc6pny	189	22	et	et	NNP
work_clhxj3r6pndirghkema3cc6pny	189	23	al	al	NNP
work_clhxj3r6pndirghkema3cc6pny	189	24	.	.	.
work_clhxj3r6pndirghkema3cc6pny	190	1	The	the	DT
work_clhxj3r6pndirghkema3cc6pny	190	2	pharmacokinetics	pharmacokinetic	NNS
work_clhxj3r6pndirghkema3cc6pny	190	3	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	190	4	codeine	codeine	NN
work_clhxj3r6pndirghkema3cc6pny	190	5	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	190	6	its	-PRON-	PRP$
work_clhxj3r6pndirghkema3cc6pny	190	7	metabolites	metabolite	NNS
work_clhxj3r6pndirghkema3cc6pny	190	8	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	190	9	Blacks	black	NNS
work_clhxj3r6pndirghkema3cc6pny	190	10	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	190	11	sickle	sickle	NN
work_clhxj3r6pndirghkema3cc6pny	190	12	cell	cell	NN
work_clhxj3r6pndirghkema3cc6pny	190	13	disease	disease	NN
work_clhxj3r6pndirghkema3cc6pny	190	14	.	.	.
work_clhxj3r6pndirghkema3cc6pny	191	1	Eur	Eur	NNP
work_clhxj3r6pndirghkema3cc6pny	191	2	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	191	3	Clin	Clin	NNP
work_clhxj3r6pndirghkema3cc6pny	191	4	Pharmacol	Pharmacol	NNP
work_clhxj3r6pndirghkema3cc6pny	191	5	.	.	.
work_clhxj3r6pndirghkema3cc6pny	192	1	2009;65(7):651	2009;65(7):651	LS
work_clhxj3r6pndirghkema3cc6pny	192	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	192	3	658	658	CD
work_clhxj3r6pndirghkema3cc6pny	192	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	193	1	22	22	CD
work_clhxj3r6pndirghkema3cc6pny	193	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	194	1	McGregor	McGregor	NNP
work_clhxj3r6pndirghkema3cc6pny	194	2	LM	LM	NNP
work_clhxj3r6pndirghkema3cc6pny	194	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	194	4	Stewart	Stewart	NNP
work_clhxj3r6pndirghkema3cc6pny	194	5	CF	CF	NNP
work_clhxj3r6pndirghkema3cc6pny	194	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	194	7	Crews	Crews	NNP
work_clhxj3r6pndirghkema3cc6pny	194	8	KR	KR	NNP
work_clhxj3r6pndirghkema3cc6pny	194	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	194	10	Tagen	Tagen	NNP
work_clhxj3r6pndirghkema3cc6pny	194	11	M	M	NNP
work_clhxj3r6pndirghkema3cc6pny	194	12	,	,	,
work_clhxj3r6pndirghkema3cc6pny	194	13	Wozni-	Wozni-	NNP
work_clhxj3r6pndirghkema3cc6pny	194	14	ak	ak	NNP
work_clhxj3r6pndirghkema3cc6pny	194	15	A	A	NNP
work_clhxj3r6pndirghkema3cc6pny	194	16	,	,	,
work_clhxj3r6pndirghkema3cc6pny	194	17	Wu	Wu	NNP
work_clhxj3r6pndirghkema3cc6pny	194	18	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	194	19	,	,	,
work_clhxj3r6pndirghkema3cc6pny	194	20	McCarville	McCarville	NNP
work_clhxj3r6pndirghkema3cc6pny	194	21	MB	MB	NNP
work_clhxj3r6pndirghkema3cc6pny	194	22	,	,	,
work_clhxj3r6pndirghkema3cc6pny	194	23	et	et	NNP
work_clhxj3r6pndirghkema3cc6pny	194	24	al	al	NNP
work_clhxj3r6pndirghkema3cc6pny	194	25	.	.	.
work_clhxj3r6pndirghkema3cc6pny	195	1	Dose	dose	VB
work_clhxj3r6pndirghkema3cc6pny	195	2	escalation	escalation	NN
work_clhxj3r6pndirghkema3cc6pny	195	3	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	195	4	in-	in-	JJ
work_clhxj3r6pndirghkema3cc6pny	195	5	travenous	travenous	JJ
work_clhxj3r6pndirghkema3cc6pny	195	6	irinotecan	irinotecan	NNP
work_clhxj3r6pndirghkema3cc6pny	195	7	using	use	VBG
work_clhxj3r6pndirghkema3cc6pny	195	8	oral	oral	JJ
work_clhxj3r6pndirghkema3cc6pny	195	9	cefpodoxime	cefpodoxime	NN
work_clhxj3r6pndirghkema3cc6pny	195	10	:	:	:
work_clhxj3r6pndirghkema3cc6pny	195	11	a	a	DT
work_clhxj3r6pndirghkema3cc6pny	195	12	phase	phase	NN
work_clhxj3r6pndirghkema3cc6pny	195	13	I	-PRON-	PRP
work_clhxj3r6pndirghkema3cc6pny	195	14	study	study	VBP
work_clhxj3r6pndirghkema3cc6pny	195	15	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	195	16	pediatric	pediatric	JJ
work_clhxj3r6pndirghkema3cc6pny	195	17	patients	patient	NNS
work_clhxj3r6pndirghkema3cc6pny	195	18	with	with	IN
work_clhxj3r6pndirghkema3cc6pny	195	19	refractory	refractory	JJ
work_clhxj3r6pndirghkema3cc6pny	195	20	solid	solid	JJ
work_clhxj3r6pndirghkema3cc6pny	195	21	tumors	tumor	NNS
work_clhxj3r6pndirghkema3cc6pny	195	22	.	.	.
work_clhxj3r6pndirghkema3cc6pny	196	1	Pediatr	Pediatr	NNP
work_clhxj3r6pndirghkema3cc6pny	196	2	Blood	Blood	NNP
work_clhxj3r6pndirghkema3cc6pny	196	3	Cancer	Cancer	NNP
work_clhxj3r6pndirghkema3cc6pny	196	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	197	1	2012;58(3):372	2012;58(3):372	CD
work_clhxj3r6pndirghkema3cc6pny	197	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	197	3	379	379	CD
work_clhxj3r6pndirghkema3cc6pny	197	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	198	1	23	23	CD
work_clhxj3r6pndirghkema3cc6pny	198	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	199	1	Neafsey	Neafsey	NNP
work_clhxj3r6pndirghkema3cc6pny	199	2	P	P	NNP
work_clhxj3r6pndirghkema3cc6pny	199	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	199	4	Ginsberg	Ginsberg	NNP
work_clhxj3r6pndirghkema3cc6pny	199	5	G	G	NNP
work_clhxj3r6pndirghkema3cc6pny	199	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	199	7	Hattis	Hattis	NNP
work_clhxj3r6pndirghkema3cc6pny	199	8	D	D	NNP
work_clhxj3r6pndirghkema3cc6pny	199	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	199	10	Sonawane	Sonawane	NNP
work_clhxj3r6pndirghkema3cc6pny	199	11	B.	B.	NNP
work_clhxj3r6pndirghkema3cc6pny	200	1	Genetic	genetic	JJ
work_clhxj3r6pndirghkema3cc6pny	200	2	polymorphism	polymorphism	NN
work_clhxj3r6pndirghkema3cc6pny	200	3	in	in	IN
work_clhxj3r6pndirghkema3cc6pny	200	4	cytochrome	cytochrome	JJ
work_clhxj3r6pndirghkema3cc6pny	200	5	P450	P450	NNP
work_clhxj3r6pndirghkema3cc6pny	200	6	2D6	2D6	NNP
work_clhxj3r6pndirghkema3cc6pny	200	7	(	(	-LRB-
work_clhxj3r6pndirghkema3cc6pny	200	8	CYP2D6	CYP2D6	NNP
work_clhxj3r6pndirghkema3cc6pny	200	9	)	)	-RRB-
work_clhxj3r6pndirghkema3cc6pny	200	10	:	:	:
work_clhxj3r6pndirghkema3cc6pny	200	11	Pop-	Pop-	NNP
work_clhxj3r6pndirghkema3cc6pny	200	12	ulation	ulation	NN
work_clhxj3r6pndirghkema3cc6pny	200	13	distribution	distribution	NN
work_clhxj3r6pndirghkema3cc6pny	200	14	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	200	15	CYP2D6	cyp2d6	JJ
work_clhxj3r6pndirghkema3cc6pny	200	16	activity	activity	NN
work_clhxj3r6pndirghkema3cc6pny	200	17	.	.	.
work_clhxj3r6pndirghkema3cc6pny	201	1	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	201	2	Toxicol	Toxicol	NNP
work_clhxj3r6pndirghkema3cc6pny	201	3	Envi-	Envi-	NNPS
work_clhxj3r6pndirghkema3cc6pny	201	4	ron	ron	NNP
work_clhxj3r6pndirghkema3cc6pny	201	5	Health	Health	NNP
work_clhxj3r6pndirghkema3cc6pny	201	6	B	B	NNP
work_clhxj3r6pndirghkema3cc6pny	201	7	Crit	Crit	NNP
work_clhxj3r6pndirghkema3cc6pny	201	8	Rev.	Rev.	NNP
work_clhxj3r6pndirghkema3cc6pny	202	1	2009;12(5	2009;12(5	LS
work_clhxj3r6pndirghkema3cc6pny	202	2	-	-	:
work_clhxj3r6pndirghkema3cc6pny	202	3	6):334	6):334	NN
work_clhxj3r6pndirghkema3cc6pny	202	4	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	202	5	361	361	CD
work_clhxj3r6pndirghkema3cc6pny	202	6	.	.	.
work_clhxj3r6pndirghkema3cc6pny	203	1	24	24	CD
work_clhxj3r6pndirghkema3cc6pny	203	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	204	1	Lotsch	Lotsch	NNP
work_clhxj3r6pndirghkema3cc6pny	204	2	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	204	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	204	4	Skarke	Skarke	NNP
work_clhxj3r6pndirghkema3cc6pny	204	5	C	C	NNP
work_clhxj3r6pndirghkema3cc6pny	204	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	204	7	Liefhold	Liefhold	NNP
work_clhxj3r6pndirghkema3cc6pny	204	8	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	204	9	,	,	,
work_clhxj3r6pndirghkema3cc6pny	204	10	Geisslinger	Geisslinger	NNP
work_clhxj3r6pndirghkema3cc6pny	204	11	G.	G.	NNP
work_clhxj3r6pndirghkema3cc6pny	204	12	Genetic	Genetic	NNP
work_clhxj3r6pndirghkema3cc6pny	204	13	predictors	predictor	NNS
work_clhxj3r6pndirghkema3cc6pny	204	14	of	of	IN
work_clhxj3r6pndirghkema3cc6pny	204	15	the	the	DT
work_clhxj3r6pndirghkema3cc6pny	204	16	clinical	clinical	JJ
work_clhxj3r6pndirghkema3cc6pny	204	17	response	response	NN
work_clhxj3r6pndirghkema3cc6pny	204	18	to	to	IN
work_clhxj3r6pndirghkema3cc6pny	204	19	opioid	opioid	JJ
work_clhxj3r6pndirghkema3cc6pny	204	20	analgesics	analgesic	NNS
work_clhxj3r6pndirghkema3cc6pny	204	21	:	:	:
work_clhxj3r6pndirghkema3cc6pny	204	22	clinical	clinical	JJ
work_clhxj3r6pndirghkema3cc6pny	204	23	utility	utility	NN
work_clhxj3r6pndirghkema3cc6pny	204	24	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	204	25	future	future	JJ
work_clhxj3r6pndirghkema3cc6pny	204	26	perspectives	perspective	NNS
work_clhxj3r6pndirghkema3cc6pny	204	27	.	.	.
work_clhxj3r6pndirghkema3cc6pny	205	1	Clin	Clin	NNP
work_clhxj3r6pndirghkema3cc6pny	205	2	Pharmacoki-	Pharmacoki-	NNP
work_clhxj3r6pndirghkema3cc6pny	205	3	net	net	NN
work_clhxj3r6pndirghkema3cc6pny	205	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	206	1	2004;43(14):983	2004;43(14):983	CD
work_clhxj3r6pndirghkema3cc6pny	206	2	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	206	3	1013	1013	CD
work_clhxj3r6pndirghkema3cc6pny	206	4	.	.	.
work_clhxj3r6pndirghkema3cc6pny	207	1	25	25	CD
work_clhxj3r6pndirghkema3cc6pny	207	2	.	.	.
work_clhxj3r6pndirghkema3cc6pny	208	1	Jameson	Jameson	NNP
work_clhxj3r6pndirghkema3cc6pny	208	2	JL	JL	NNP
work_clhxj3r6pndirghkema3cc6pny	208	3	,	,	,
work_clhxj3r6pndirghkema3cc6pny	208	4	Longo	Longo	NNP
work_clhxj3r6pndirghkema3cc6pny	208	5	DL	DL	NNP
work_clhxj3r6pndirghkema3cc6pny	208	6	.	.	.
work_clhxj3r6pndirghkema3cc6pny	209	1	Precision	precision	NN
work_clhxj3r6pndirghkema3cc6pny	209	2	medicine	medicine	NN
work_clhxj3r6pndirghkema3cc6pny	209	3	-	-	HYPH
work_clhxj3r6pndirghkema3cc6pny	209	4	person-	person-	NN
work_clhxj3r6pndirghkema3cc6pny	209	5	alized	alize	VBD
work_clhxj3r6pndirghkema3cc6pny	209	6	,	,	,
work_clhxj3r6pndirghkema3cc6pny	209	7	problematic	problematic	JJ
work_clhxj3r6pndirghkema3cc6pny	209	8	,	,	,
work_clhxj3r6pndirghkema3cc6pny	209	9	and	and	CC
work_clhxj3r6pndirghkema3cc6pny	209	10	promising	promising	NN
work_clhxj3r6pndirghkema3cc6pny	209	11	.	.	.
work_clhxj3r6pndirghkema3cc6pny	210	1	N	N	NNP
work_clhxj3r6pndirghkema3cc6pny	210	2	Engl	Engl	NNP
work_clhxj3r6pndirghkema3cc6pny	210	3	J	J	NNP
work_clhxj3r6pndirghkema3cc6pny	210	4	Med	Med	NNP
work_clhxj3r6pndirghkema3cc6pny	210	5	.	.	.
work_clhxj3r6pndirghkema3cc6pny	211	1	2015;372(23):2229	2015;372(23):2229	CD
work_clhxj3r6pndirghkema3cc6pny	211	2	-	-	SYM
work_clhxj3r6pndirghkema3cc6pny	211	3	2234	2234	CD
work_clhxj3r6pndirghkema3cc6pny	211	4	.	.	.