id author title date pages extension mime words sentences flesch summary cache txt work_whsxjmpdbneuphtgnym6ryfc7q Gisela Beutner Initiation of Electron Transport Activity and a Decrease of Oxidative Stress Occur Simultaneously during Embryonic Heart Development 2015 1 .pdf application/pdf 1569 116 44 Initiation of Electron Transport Activity and a Decrease of Oxidative Stress Occur Simultaneously during Embryonic Heart Development We investigated the kinetics of MAC inhibition in mitochondria from wild type, Bak, and Bax knockout cell lines using Here we show that adrenergic signaling induces MCU tyrosine phosphorylation and accelerates mitochondrial Ca Pyk2 and MCU, which subsequently accelerates mitochondrial Ca2รพ uptake via confirmed that only two tyrosine sites were phosphorylated in response to adrenergic stimulation in situ using cell lines stably expressing MCU-YFs. In addition, overexpression of these MCU-YFs failed to increase mitochondrial Ca is required for activation of Akt survival pathways and mitochondrial function. At embryonic day (E) 9.5, mitochondrial ETC activity and oxidative phosphorylation (OXPHOS) are not coupled, Initiation of Electron Transport Activity and a Decrease of Oxidative Stress Occur Simultaneously during Embryonic Heart De ... The Stoichiometry between MICU1 and MCU Determines the Different Mitochondrial Ca2+ Uptake Phenotypes in Heart and Liver ./cache/work_whsxjmpdbneuphtgnym6ryfc7q.pdf ./txt/work_whsxjmpdbneuphtgnym6ryfc7q.txt