id author title date pages extension mime words sentences flesch summary cache txt work_s64wlochtbh2vfjqkrdoyu35ye Oscar Teijido Hermida A Step Forward in Understanding the Mechanism of VDAC Voltage-Gating 2013 1 .pdf application/pdf 1580 128 52 The voltage dependent anion channel (VDAC) is involved in regulation of metabolite flux across the mitochondrial outer membrane (MOM). The 15 amino acid N-terminal sequence of HXK2 is responsible for mitochondrial binding and, when G6P, which is known to cause HXK2 detachment from the MOM, fully reverses the inhibition of tubulin-VDAC binding. Thus we propose a novel mechanism of mitochondrial respiration control in cancer cells through the competition between HXK2 and tubulin for VDAC binding. matrix [Ca2รพ] response in permeabilized shMICU1 cells. MICU1-dependent Threshold and Cooperativity of Mitochondrial Ca of MICU1 in HeLa cells causes lower threshold and decreased cooperativity of Silencing of MICU1 caused a leftward-shifted dose response and decreased cooperativity of mitochondrial Novel Mechanism of Mitochondrial Respiration Control through Competition between Hexokinase-2 and Tubulin for VDAC Binding Reprogramming of Mitochondrial Ca2+ Handling in MICU1-Deficient HeLa Cells MICU1-dependent Threshold and Cooperativity of Mitochondrial Ca2+ Uptake in the Liver ./cache/work_s64wlochtbh2vfjqkrdoyu35ye.pdf ./txt/work_s64wlochtbh2vfjqkrdoyu35ye.txt