id author title date pages extension mime words sentences flesch summary cache txt work_gewu5p6lcvepvfwrwrwkxnnwci David Weaver Shuttling of Membrane-Bound Cytochrome B5 between Mitochondria and ER 2012 1 .pdf application/pdf 1451 113 36 mitochondrial membranes which result in the dramatic increase of their permeability. study investigated how mtDNA T8993G (NARP)-induced inhibition of mitochondrial complex V altered mitochondrial dynamics in association with a protective mitochondrial phospholipid, cardiolipin (CL), as a potential therapeutic a result of three distinct lethal mitochondrial apoptotic insults including oxidative, Ca2þ and lipidstress. Intriguingly, melatonin, by differentially preserving CL during various stresses (oxidation > Ca2þ > lipid), rescuesdifferentially CL-altered mitochondrial dynamics and cell death (oxidation > CL to prevent its oxidization and/or depletion and, therefore, it exerts great potential in rescuing CL-dependent mitochondrial dynamics-associated mitochondrial pathologies for treatment of NARP-induced pathologies and diseases. of an outer mitochondrial membrane protein. Tunde Golenar1, Gyorgy Csordas1, Fabiana Perocchi2, Vamsi K. MICU1 in mitochondrial Ca2þ uptake, we used wild type HeLa cells (Ctrl), mtDNA T8993G Mutation-Induced Mitochondrial Complex V Inhibition Augments Cardiolipin-Dependent Alterations of Mitochondria ... Dichotomy between Mitochondrial Ca2+ Uptake and Martix [Ca2+] in MICU1 Deficient Cells ./cache/work_gewu5p6lcvepvfwrwrwkxnnwci.pdf ./txt/work_gewu5p6lcvepvfwrwrwkxnnwci.txt