id author title date pages extension mime words sentences flesch summary cache txt work_cdb3mgp56nhutjnqc54ksdhrjm Xingguo Liu Biophysical Properties of Mitochondria Undergoing Fusion 2010 1 .pdf application/pdf 1427 100 41 formation and fusion, we used organelle-targeted fluorescent proteins, including photoactivatable GFP, which allow tracking of individual mitochondria. Strikingly, 80-90% of the physical contacts between adjacent mitochondria did not result in fusion events. ionophore that induces matrix swelling evoked a decrease in mitochondrial motility leading to fewer contacts among mitochondria but the number of fusion Here we evaluated mitochondrial fusion dynamics in human skeletal muscle cells (HUSMC). Mitochondrial fusion events were evaluated by confocal imaging of cells expressing mitochondria matrix targeted DsRed and Recent studies have suggested that type 3 IP3Rs (IP3R3) are particularly important for mediating the Ca2þ transfer at the ER-mitochondrial interface. in the mitochondrial Ca2þ transfer we used two point mutants of the IP3R1, each IP3R isoform can support local ER-mitochondrial Ca2þ transfer and their Mitochondrial Fusion Dynamics in Human Skeletal Muscle-Derived Cells Mitochondrial Fusion Dynamics in Human Skeletal Muscle-Derived Cells ./cache/work_cdb3mgp56nhutjnqc54ksdhrjm.pdf ./txt/work_cdb3mgp56nhutjnqc54ksdhrjm.txt