id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
work_3xxhy2hklbhwtaua3prq2lvyzq	Nicholaos Jones	Strategies of Explanatory Abstraction in Molecular Systems Biology	2018	16	.pdf	application/pdf	4952	316	38	Strategies of Explanatory Abstraction in Molecular Systems Biology perfect adaptation of chemotaxis in Escherichia coli (Barkai and Leibler 1997; Ma et al Mechanistic network for E.coli chemotaxis (Rao and Ordal 2009). the dynamical modeling strategy produces accounts that are mechanistic, by virtue of Let's treat the dynamical model driving this explanatory strategy as an initial baseline for dynamical modeling, represent mechanisms for E.coli chemotaxis. The topological analysis strategy proceeds by identifying a chemotaxis network known if the mechanistic details of E.coli's chemotaxis network were different, and even if the The topological model driving this second explanatory strategy is more abstract than the chemotaxis network for E.coli nor topological details about the structure of that dynamical, topological, and design explanatory strategies differ as I claim—specifically, mechanistic explanation for the perfect robustness of chemotaxis for B.subtilis. chemotaxis (in E.coli, B.subtilis, etc) apply mathematical techniques to network models. Then topological and organizational design explanatory strategies are mechanistic 	./cache/work_3xxhy2hklbhwtaua3prq2lvyzq.pdf	./txt/work_3xxhy2hklbhwtaua3prq2lvyzq.txt