[PDF] Mouse models of Rett syndrome: from behavioural phenotyping to preclinical evaluation of new therapeutic approaches | Semantic Scholar Skip to search formSkip to main content> Semantic Scholar's Logo Search Sign InCreate Free Account You are currently offline. Some features of the site may not work correctly. DOI:10.1097/FBP.0b013e32830c3645 Corpus ID: 33364486Mouse models of Rett syndrome: from behavioural phenotyping to preclinical evaluation of new therapeutic approaches @article{Ricceri2008MouseMO, title={Mouse models of Rett syndrome: from behavioural phenotyping to preclinical evaluation of new therapeutic approaches}, author={L. Ricceri and B. De Filippis and G. Laviola}, journal={Behavioural Pharmacology}, year={2008}, volume={19}, pages={501-517} } L. Ricceri, B. De Filippis, G. Laviola Published 2008 Medicine Behavioural Pharmacology Rett syndrome (RTT) is a neurodevelopmental disorder, primarily affecting girls. RTT causes severe cognitive, social, motor and physiological impairments and no cure currently exists. The discovery of a monogenic origin for RTT and the subsequent generation of RTT mouse models provided a major breakthrough for RTT research. Although the characterization of these mutant mice is far from complete, they recapitulate several RTT symptoms. This review provides an overview of the behavioural domains… Expand View on Wolters Kluwer rettsearch.org Save to Library Create Alert Cite Launch Research Feed Share This Paper 94 CitationsHighly Influential Citations 7 Background Citations 44 Methods Citations 6 Results Citations 9 View All Topics from this paper Rett Syndrome Neurodevelopmental Disorders Phenotype determination Evaluation Pharmacology 94 Citations Citation Type Citation Type All Types Cites Results Cites Methods Cites Background Has PDF Publication Type Author More Filters More Filters Filters Sort by Relevance Sort by Most Influenced Papers Sort by Citation Count Sort by Recency Rett syndrome treatment in mouse models: Searching for effective targets and strategies L. Ricceri, B. D. Filippis, G. Laviola Biology, Medicine Neuropharmacology 2013 34 Save Alert Research Feed Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome S. Veeraragavan, Y. Wan, +15 authors R. Samaco Biology, Medicine Human molecular genetics 2016 33 PDF View 1 excerpt Save Alert Research Feed The complexity of Rett syndrome models: Primary fibroblasts as a disease-in-a-dish reliable approach V. Cordone, Alessandra Pecorelli, F. Amicarelli, J. Hayek, G. Valacchi Medicine 2019 4 Save Alert Research Feed Experimental models of Rett syndrome based on Mecp2 dysfunction G. Calfa, A. Percy, L. Pozzo-Miller Biology, Medicine Experimental biology and medicine 2011 115 Save Alert Research Feed Deficient Purposeful Use of Forepaws in Female Mice Modelling Rett Syndrome B. De Filippis, M. Musto, L. Altabella, E. Romano, R. Canese, G. Laviola Psychology, Medicine Neural plasticity 2015 16 PDF Save Alert Research Feed Analysis of the Serotonergic System in a Mouse Model of Rett Syndrome Reveals Unusual Upregulation of Serotonin Receptor 5b S. Vogelgesang, Sabine Niebert, +4 authors M. Niebert Biology, Medicine Front. Mol. Neurosci. 2017 15 View 1 excerpt, cites background Save Alert Research Feed Rett Syndrome and MeCP2 V. Liyanage, M. Rastegar Biology, Medicine NeuroMolecular Medicine 2014 76 View 1 excerpt, cites methods Save Alert Research Feed Long-lasting beneficial effects of central serotonin receptor 7 stimulation in female mice modeling Rett syndrome B. De Filippis, V. Chiodi, +6 authors G. Laviola Psychology, Medicine Front. Behav. Neurosci. 2015 30 View 2 excerpts, cites results Save Alert Research Feed Stimulation of the brain serotonin receptor 7 rescues mitochondrial dysfunction in female mice from two models of Rett syndrome D. Valenti, Lidia de Bari, D. Vigli, E. Lacivita, Bianca De Filippis Biology, Medicine Neuropharmacology 2017 18 PDF Save Alert Research Feed Rett syndrome and the urge of novel approaches to study MeCP2 functions and mechanisms of action F. Bedogni, R. Rossi, F. Galli, Clementina Cobolli Gigli, N. Landsberger Biology, Medicine Neuroscience & Biobehavioral Reviews 2014 45 Save Alert Research Feed ... 1 2 3 4 5 ... References SHOWING 1-10 OF 117 REFERENCES SORT BYRelevance Most Influenced Papers Recency Evidence for abnormal early development in a mouse model of Rett syndrome M. Santos, A. Silva‐Fernandes, P. Oliveira, N. Sousa, P. Maciel Psychology, Medicine Genes, brain, and behavior 2007 82 Highly Influential View 8 excerpts, references background and results Save Alert Research Feed Behavioral and anatomical abnormalities in Mecp2 mutant mice: A model for Rett syndrome N. A. Stearns, L. R. Schaevitz, H. Bowling, N. Nag, J. Berger-Sweeney Psychology, Medicine Neuroscience 2007 187 Highly Influential PDF View 9 excerpts, references background and methods Save Alert Research Feed Mouse Behavioral Assays Relevant to the Symptoms of Autism * J. 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Villard Medicine The European journal of neuroscience 2007 124 PDF View 2 excerpts, references results and background Save Alert Research Feed A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome J. Guy, B. Hendrich, M. Holmes, J. Martin, A. Bird Biology, Medicine Nature Genetics 2001 1,403 Highly Influential PDF View 9 excerpts, references methods and background Save Alert Research Feed Comparative study of brain morphology in Mecp2 mutant mouse models of Rett syndrome Nadia P. Belichenko, P. Belichenko, H. Li, W. Mobley, U. Francke Biology, Medicine The Journal of comparative neurology 2008 76 PDF View 1 excerpt, references results Save Alert Research Feed Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. A. L. Collins, J. Levenson, +5 authors H. Zoghbi Medicine, Biology Human molecular genetics 2004 527 PDF View 2 excerpts, references background Save Alert Research Feed ... 1 2 3 4 5 ... 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